Patents Represented by Attorney, Agent or Law Firm Michael R. Williams
  • Patent number: 8029814
    Abstract: Described herein is (E)-6,10-dimethyl-5,9-undecadien-2-ol (geranyl acetol), termed here fuscumol, which has been identified as a male-produced pheromone emitted by Tetropium fuscum (F.) and Tetropium cinnamopterum. Also described are novel derivatives thereof e.g. esters, methods for the synthesis thereof and to a composition comprising fuscumol plus host volatiles e.g. a synthetic blend of monoterpenes plus ethanol, for attracting male and female T. fuscum and female T. cinnamopterum.
    Type: Grant
    Filed: September 25, 2008
    Date of Patent: October 4, 2011
    Assignee: Her Majesty the Queen in Right of Canada as represented by the Minister of Natural Resources, Canada, Canadian Forest Service
    Inventors: Peter Silk, Jon Sweeney
  • Patent number: 8012489
    Abstract: Recombinant VSV viral particles and the use thereof as vaccines for immunization are described.
    Type: Grant
    Filed: July 28, 2003
    Date of Patent: September 6, 2011
    Inventors: Steven Jones, Heinz Feldmann, Ute Stroeher
  • Patent number: 7964341
    Abstract: The invention relates to the discovery of a human endogenous retrovirus (HERV) family, Type I HERV-K (HML-2) which appear to be active in vitro and in vivo, infectious, and which have the have the salient features and properties of foamy retroviruses. Based on its natural replication in humans, and that it protects the host from viral and tumor transformation, this non-pathogenic endogenous virus could be developed as a replication competent gene therapy vector. It also is expected to have much higher efficacy than other vectors as it crosses the bloodbrain barrier and infects almost all cell types in the host (proliferating or not). It may naturally lyse tumor cells or infected cells, and thus could even be used without genetic modification. Of course, this vector could be used in traditional ways with it ability to replicate genetically removed.
    Type: Grant
    Filed: March 20, 2006
    Date of Patent: June 21, 2011
    Inventors: Marian Laderoute, Antonio Giulivi, Francisco Diaz-Mitoma, Louise Larocque
  • Patent number: 7820171
    Abstract: Herein, it is shown that strong specific anti-methanogen avian antibodies can be produced when chickens are immunized with an optimal dose of methane producing bacterial antigen (methanogen) formulated with an appropriate adjuvant. The antibodies can in turn be used to reduce methane gas production from an animal by administering an effective amount of the anti-methanogen antibodies to the animal, thereby reducing methane gas evolved by the animal compared to an untreated or mock treated control animal of similar age and condition.
    Type: Grant
    Filed: April 14, 2008
    Date of Patent: October 26, 2010
    Inventor: Pradip Maiti
  • Patent number: 7814863
    Abstract: Methods and systems for providing liquid feed to livestock deliver the liquid feed to a feeding station at a temperature below that of the mother's natural milk to encourage use of the liquid feed by the young as a supplement and not a replacement. A second reservoir expands the capacity of the system without increasing the size of the mixing reservoir. The second reservoir is equipped with selectively operable refrigeration and heating elements to facilitate cooling of the liquid feed or heating of a cleaning solution. A peroxide doser introduces small quantifies of peroxide to clean the liquid feed and prevent gorging. Orifices through which feed is discharged at feeding stations decrease in cross sectional area along the circulation line in the direction of flow to counteract variation in discharge flow rates caused by a pressure differential in the liquid feed along the line.
    Type: Grant
    Filed: October 24, 2007
    Date of Patent: October 19, 2010
    Inventors: John Hare, Gerard Grant Coyston
  • Patent number: 7419108
    Abstract: A method of corn fractionation wherein the resulting high starch concentration endosperm is subsequently used for ethanol production or dry milling is described. The method includes: providing substantially cleaned corn kernels, tempering the corn; screen processing to properly size the com fractions; density separation of the primary fractions; rolling and/or screening the products to produce three main fractions consisting of high starch Endosperm, high oil Germ and high fiber Bran.
    Type: Grant
    Filed: February 7, 2006
    Date of Patent: September 2, 2008
    Inventor: Glen Foster
  • Patent number: 7410589
    Abstract: The invention relates to a method of treating manure such that odor from the manure is significantly reduced or eliminated and producing therefrom recyclable water, value-added biosolids and ammonia. Specifically, the manure is combined with lime at high pH. The material is mixed under negative pressure and the basic conditions cause ammonia to be evolved from the manure which is then drawn off and recovered. A coagulating agent is then added which further promotes floc formation within the manure. Following further mixing, flocs are separated from the liquid portion. A struvite-promoting chemical and a coagulant are then added to the liquid portion which causes further floc formation, and the flocs are again separated from the substantially clear liquid. It is of note that as a result of this process, the solids are highly hydrophobic and dry very quickly. It is of further note that solids isolated from either step can be combined and sold, for example, as fertilizer, as discussed below.
    Type: Grant
    Filed: July 26, 2002
    Date of Patent: August 12, 2008
    Inventor: Gurunathan Lakshman
  • Patent number: 7410522
    Abstract: A liquid fertilizer is described. The fertilizer comprises a mixture of soluble and insoluble forms of nutrients. The fertilizer provides both quick release and slow release nutrients to plants, meaning that a single application of the fertilizer supplies nutrients to growing plants for an extended period of time, from 1-28 days.
    Type: Grant
    Filed: November 7, 2001
    Date of Patent: August 12, 2008
    Inventor: Kerry Green
  • Patent number: 7402575
    Abstract: Methods and compositions for treating myocardial dysfunction or inflammation are described. The methods of the invention involve administering an agent that can inhibit lysozyme to an animal in need thereof. Preferred lysozyme inhibitors include TAC and chitobiose.
    Type: Grant
    Filed: January 23, 2004
    Date of Patent: July 22, 2008
    Inventors: Steven N. Mink, Hans Jacobs, Deepak Bose, Krika Duke, R. Bruce Light
  • Patent number: 7399872
    Abstract: Methods of converting cannabidiol to ?8-tetrahydrocannabinol or ?9-tetrahydrocannabinol are described. The described methods produce higher yields and higher purity compared to prior art methods.
    Type: Grant
    Filed: March 7, 2002
    Date of Patent: July 15, 2008
    Inventors: G. R. Barrie Webster, Leonard P. Sarna, Raphael Mechoulam
  • Patent number: 7393997
    Abstract: The present invention relates to methods for the use of the Arabidopsis “BREVIPEDICELLUS” (BP) gene for alteration of plant architecture, in particular alteration of the morphology of the inflorescence of a flowering plant. The methods of the present invention provide a means to alter the development of the peduncle, notably the inflorescence branches, and the pedicels that subtend the individual flowers as well as aspects of flower structure such as the style, and subsequent seed pods, of a flowering plant. The invention also relates to methods to identify and isolate polynucleotides encoding genes with BP-related functions from other plant species and methods for utilizing said polynucleotides to alter the inflorescence of said plant species. Furthermore, the invention encompasses transgenic plants generated by the methods disclosed, and nucleotide sequences for use in generating the transgenic plants.
    Type: Grant
    Filed: March 28, 2002
    Date of Patent: July 1, 2008
    Inventors: Raju Datla, Tim Dumonceaux, Prakash Venglat, Vivijan Babic, Wilf Keller, Gopalan Selvaraj
  • Patent number: 7355092
    Abstract: Genetic vaccine which comprises plasmid(s) containing genes coding for antigens of enterotoxigenic Escherichia coli (ETEC) strains is disclosed. Additionally, plasmids may consist of multiple copies of the same antigen (i.e. K88 or K99 fimbrial antigen) or multiple antigens (ie. K88 and K99 fimbrial antigens) and genetic adjuvants such as cytokines (IL-2, IL-4 & GM-CSF), costimulatory molecules (CD80 & CD86) or chemokines or immunostimulatory sequences. A method for isolating antibodies from chicken egg yolk for passive immunization of animals, as well as humans to control diarrhoeal diseases using the genetic vaccines is also disclosed.
    Type: Grant
    Filed: December 27, 2000
    Date of Patent: April 8, 2008
    Inventors: Ronald Marquardt, Suk-Hyeon Cho, Peter Loewen, Srinivasa Madhyastha
  • Patent number: 7323617
    Abstract: A transgenic mouse whose genome comprises a Tie-2 promoter operably linked to a cDNA encoding calreticulin (CRT) is described.
    Type: Grant
    Filed: February 5, 2007
    Date of Patent: January 29, 2008
    Inventor: Nasrin Mesaeli
  • Patent number: 7318930
    Abstract: A composition which causes adult boring bark beetles to discontinue boring, discontinue laying eggs and become disoriented and bore out of the tree or cease boring altogether and die is described. Additional tests have shown that beetles will not infest a tree which has been treated with the composition. Furthermore, the composition also causes beetle larvae to cease boring and die and also causes egg sacks to shrivel and die.
    Type: Grant
    Filed: November 6, 2002
    Date of Patent: January 15, 2008
    Inventor: William Steed
  • Patent number: 7297838
    Abstract: Development of an efficient and cost-effective doubled haploid production system and genetic transformation system are the prerequisite to initiate haploid breeding and genetic modification in flax respectively. Pre-culturing anthers on a high osmotic, high auxin and high mineral salt concentration for a period of time before transfer to a low osmotic, low auxin and low salt concentration significantly increased the overall efficiency of regeneration or anther efficiency than directly culturing anthers on a low osmotic, low auxin and low salt concentration medium. This culture procedure also dramatically reduced the frequency of shoot regeneration from somatic cells in anther culture. Using this procedure, a highly efficient anther culture-derived callus based transformation system was developed.
    Type: Grant
    Filed: November 12, 2002
    Date of Patent: November 20, 2007
    Inventors: Yurong Chen, Joseph Clifford Paul Dribnenki
  • Patent number: 7280866
    Abstract: A non-invasive tool for skin disease diagnosis would be a useful clinical adjunct. The purpose of this study was to determine whether visible/near-infrared spectroscopy can be used to non-invasively characterize skin diseases. In-vivo visible- and near-infrared spectra (400-2500 nm) of skin neoplasms (actinic keratoses, basal cell carcinomata, banal common acquired melanocytic nevi, dysplastic melanocytic nevi, actinic lentigines and seborrheic keratoses) were collected by placing a fiber optic probe on the skin. Paired t-tests, repeated measures analysis of variance and linear discriminant analysis were used to determine whether significant spectral differences existed and whether spectra could be classified according to lesion type. Paired t-tests showed significant differences (p<0.05) between normal skin and skin lesions in several areas of the visible/near-infrared spectrum. In addition, significant differences were found between the lesion groups by analysis of variance.
    Type: Grant
    Filed: October 5, 2000
    Date of Patent: October 9, 2007
    Assignee: National Research Council of Canada
    Inventors: Laura M. McIntosh, Michael Jackson, Henry Mantsch, II, James R. Mansfield, A. Neil Crowson, John W. P. Toole
  • Patent number: 7201895
    Abstract: The present invention provides novel nucleic acids, novel polypeptide sequences encoded by these nucleic acids, methods for production thereof, and uses thereof, for a novel ELR-CXC chemokine receptor antagonist.
    Type: Grant
    Filed: March 1, 2002
    Date of Patent: April 10, 2007
    Assignee: University of Saskatchewan Technologies Inc.
    Inventors: John R. Gordon, Fang Li
  • Patent number: 7186882
    Abstract: A transgenic mouse whose genome comprises a transcriptional control region operably linked to a cDNA encoding calreticulin (CRT) is described.
    Type: Grant
    Filed: March 18, 2004
    Date of Patent: March 6, 2007
    Inventor: Nasrin Mesaeli
  • Patent number: 7179469
    Abstract: The use of a food portion comprising dry and/or wet distiller's grain for preventing, treating or ameliorating cardiovascular pathologies is described.
    Type: Grant
    Filed: April 30, 2004
    Date of Patent: February 20, 2007
    Inventor: Rajat Sethi
  • Patent number: 7090971
    Abstract: A method of identifying compounds capable of modulating trans-glutaminase (TG) kinase activity is described. The method involves adding a test compound to a mixture of TG and a suitable TG kinase substrate, incubating the mixture under conditions promoting TG kinase activity, and determining if the test compound activates or modulates TG kinase activity as indicated by greater than expected TG-mediated phosphorylation of the TG kinase substrate or if the test compound inhibits TG kinase activity as indicated by lower than expected TG-mediated phosphorylation of the TG kinase substrate as compared to a control comprising TG and a suitable TG kinase substrate incubated under conditions promoting TG kinase activity.
    Type: Grant
    Filed: January 24, 2005
    Date of Patent: August 15, 2006
    Inventors: Suresh Mishra, Liam J. Murphy