Abstract: A non-invasive method of testing for inflammatory bowel disease using a domain specific monoclonal antibody is described. A unique 18 residue amino acid sequence overexpressed in COX-2 has been identified for making and using the monoclonal antibody.
Abstract: The provides compounds for the treatment of sickle-cell disease. In particular, the invention provides 5-membered heterocyclic anti-sickling agents that are highly effective and non-toxic, and methods for their use. The compounds include analogues and derivatives of naturally occurring occurring 5-hydroxymethyl-2-furfuraldehyde, 5-Ethyl-2-furfuraldehyde, 5-Methyl-2-furfuraldehyde, and 2-furfuraldehyde, and prodrug forms of the compound.
Type:
Grant
Filed:
December 3, 2003
Date of Patent:
January 9, 2007
Assignee:
Xechem International, Inc.
Inventors:
Martin K. Safo, Richmond Danso-Danquah, Samuel Nokuri, Faik N. Musayev, Gajanan S. Joshi, James C. Burnett, Donald J. Abraham
Abstract: A unique writing instrument. Preferred is an open-ended barrel in a wishbone configuration. A method of producing the writing instrument is also described.
Abstract: A method for isolating viable, biologically substantially pure exfoliated fecal colonocytes at normal ambient temperature is described. Immunocoprocytes and inflammatory cells indicative of certain gastrointestinal conditions and a noninvasive method for detecting colorectal cancer are set forth. Composition of transport and suspension media for isolation of colonocytes are detailed.
Abstract: The invention discloses an isolated, biologically pure culture of a microorganism, Bacillus licheniformis, strain SB3086 for use as an environmentally desirable biofungicide. The invention also discloses a method for enhancing biofungicidal activity of a microbial agent. The inventional further discloses a nutrient composition comprising a microbial agent and a method for controlling plant fungal diseases and infestation of Aspergillis niger utilizing, said strain.
Abstract: The invention discloses a Gram-positive microorganism, Bacillus megaterium that effectively and efficiently degrades fats, oils and grease. A composition comprising said microorganism and a method for degrading fatty acids and grease are also disclosed. Availability of glycerol to the biodegrading microorganism was discovered to enhance biodegradation.
Type:
Grant
Filed:
April 23, 2002
Date of Patent:
November 16, 2004
Assignee:
Novozymes Biologicals, Inc.
Inventors:
Jessi Lind Tisinger, Domenic A. Paone, Jonathan Leder, David J. Drahos
Abstract: A unique writing instrument. Preferred is a bow shaped barrel with an arched and hinged or flexible upper member and a rigid lower member. A method of producing the writing instrument is also described.
Abstract: A comfortable grip attachment to an article. Preferred is a bristle grip in various shapes and sizes. A method of producing the grip is also described.
Abstract: The invention relates to a novel process for preparation of a biomarker specific for O-acetylated sialic acid and useful for the diagnosis, monitoring outcome of treatment and prediction of relapse of acute lymphoblastic leukemia, said process comprising the steps of (I) separating serum from the blood of patients of acute lymphoblastic leukemia; (ii) separation of low molecular weight fractions and galactose binding proteins from the serum on affinity matrix; (iii) passing the galactose free protein fraction obtained in step (ii) over another affinity matrix to capture O-acetyl sialic acid specific protein fraction; (iv) eluting specific protein fraction with a buffer at alkaline pH in the range of 8.0-11.
Abstract: The invention discloses a Gram-positive microorganism, Bacillus megaterium, that effectively and efficiently degrades fats, oils and grease. A composition comprising said microorganism and a method for degrading fatty acids and grease are also disclosed.
Type:
Grant
Filed:
May 18, 2001
Date of Patent:
November 18, 2003
Inventors:
Jessi Lind Tisinger, David Joseph Drahos, Jonathan Leder, Domenic Anthony Paone
Abstract: A method for isolating viable, biologically substantially pure exfoliated fecal colonocytes at normal ambient temperature is described. Immunocoprocytes and inflammatory cells indicative of certain gastrointestinal conditions and a noninvasive method for detecting colorectal cancer are set forth. Composition of transport and suspension media for isolation of colonocytes are detailed.
Abstract: A method for isolating viable, biologically substantially pure exfoliated fecal colonocytes at normal ambient temperature is described. Immunocoprocytes and inflammatory cells indicative of certain gastrointestinal conditions and a noninvasive method for detecting colorectal cancer are set forth. Composition of transport and suspension media for isolation of colonocytes are detailed.
Abstract: A method for isolating viable, biologically substantially pure exfoliated fecal colonocytes at normal ambient temperature is described. Immunocoprocytes and inflammatory cells indicative of certain gastrointestinal conditions and a noninvasive method for detecting colorectal cancer are set forth. Composition of transport and suspension media for isolation of colonocytes are detailed.
Abstract: The invention discloses an isolated, biologically pure culture of a microorganism, Bacillus licheniformis, strain SB3086 for use as an environmentally desirable biofungicide. The invention also discloses a formulation comprising said bacterium and a method for controlling plant fungal diseases and infestation of Aspergillis niger utilizing said strain.
Abstract: A method for isolating viable, biologically substantially pure exfoliated fecal colonocytes at normal ambient temperature is described. Immunocoprocytes and inflammatory cells indicative of certain gastrointestinal conditions and a noninvasive method for detecting colorectal cancer are set forth. Composition of transport and suspension media for isolation of colonocytes are detailed.
Abstract: The present invention is directed to a new soluble double metal salt of group IA and IIA of (−) hydroxycitric acid of general formula I:
where X is IA group metal: Li or Na or K or Rb or Cs or Fr
where Y is IIA group metal: Be or Mg or Ca or Sr or Ba or Ra
where the concentration of X in the salt varies from 1.5-51.0%,
the concentration of Y in the salts varies from 2.0-50.9%,
the concentration of HCA in the salt varies from 31.0-93.0% depending on the nature of X and Y.
This invention more particularly relates to new soluble double metal salt of group IA and IIA of (−) hydroxycitric acid of general formula II.
Abstract: A method for isolating viable, biologically substantially pure exfoliated fecal colonocytes at normal ambient temperature is described. Immunocoprocytes and inflammatory cells indicative of certain gastrointestinal conditions and a noninvasive method for detecting colorectal cancer are set forth. Composition of transport and suspension media for isolation of colonocytes are detailed.
Abstract: The present invention defines a herbal composition for the treatment of chronic obstructive pulmonary disease, bronchitis and respiratory disorders and a process for preparing the same.
Abstract: This invention relates to a process of preparing storage stable aqueous Azadirachtin containing Azadirachtin A to provide a predominant pesticidal composition which comprises the steps of diluting 50,000-100,000 ppm Azadirachtin with 25,000 to 50,000 Azadirachtin A weight/volume with ethanol water solvent in a ratio in the range 100-70:0-30 volume/volume to produce 2,000-40,000 ppm Azadirachtin containing 1,000-20,000 ppm of Azadirachtin A weight/volume. This is followed by emulsifying of the diluted Azadirachtin with non-ionic and non-toxic emulsifying agents in an amount ranging from 0.2 to 30% and neem oil 20-50% volume/volume. The pH of the emulsified diluted Azadirachtin is adjusted to 3.5 to 6.0 by adding an alkali solution. 1-2.5% of a sunscreen like p.aminobenzoic acid or its esters and 1-10% oleic acid volume/volume are added to create a micro-emulsion for stabilizing the composition with a good bio-efficacy.
Type:
Grant
Filed:
August 27, 1998
Date of Patent:
February 27, 2001
Assignee:
Dalmia Center for Research and Development