Patents Represented by Attorney Philip C. Strassburger
  • Patent number: 5402886
    Abstract: A storage container for catheters having a separable portion of the front wall detachable from the container to ease removal of the catheter from the container is disclosed. The top portion is preferably separated from the side walls along external score lines at the intersection of the front and side walls. The separable portion of the front wall is preferably hinged on the bottom edge, which is perforated, easing complete separation of the separable portion from the front wall. Internal score lines on the inside surface of the separable portion of the front wall, parallel and proximate the external score lines are preferably provided to form flaps when the top portion of the front wall is detached from the container. The flaps prevent the top of the catheter package from falling out of the container. The separable portion of the front wall enables the catheter to be easily removed from the storage container without it being damaged.
    Type: Grant
    Filed: July 16, 1993
    Date of Patent: April 4, 1995
    Assignee: Schneider (USA) Inc.
    Inventor: Timothy M. McGlinch
  • Patent number: 5385913
    Abstract: Compounds of the formula ##STR1## and the pharmaceutically acceptable salts thereof, wherein Q, X and R are as defined below. The compounds of formula I are broad spectrum mammalian antibacterial agents and exhibit favorable selectivity against procaryotic cells.
    Type: Grant
    Filed: March 26, 1992
    Date of Patent: January 31, 1995
    Assignee: Pfizer Inc.
    Inventor: Paul R. McGuirk
  • Patent number: 5380860
    Abstract: A method for preparing a compound of the formula ##STR1## wherein Q is C--H or N; R.sup.1 is C.sub.1-C.sub.4 alkyl, benzyl or p-nitrobenzyl and X and Y are independently selected from fluoro and chloro comprising reacting a compound of the formula ##STR2## wherein Q is >C--H or N; X and Y are independently selected from fluoro and chloro; and Z is fluoro, chloro, 1-imidazolyl or substituted 1-imidazolyl, wherein the 1-imidazolyl group is substituted with one or two substituents independently selected from C.sub.1 to C.sub.4 alkyl, with a compound of the formula[M.sup.n+ ].sub.p [V.sup.p- ].sub.nwherein M is an alkaline earth metal, Cu or Mn, n is 2, V.sup.p-, wherein p is 1 or 2, is an anion of the formula ##STR3## or a dianion of the formula ##STR4## and R.sup.1 is C.sub.1 to C.sub.6 alkyl or paranitrobenzyl, with the proviso that when Z is 1-imidazolyl or substituted 1-imidazole, M is magnesium, copper or manganese and with the proviso that when Z is fluoro, chloro or bromo, V.sup.
    Type: Grant
    Filed: January 24, 1992
    Date of Patent: January 10, 1995
    Assignee: Pfizer Inc.
    Inventors: Frank R. Busch, Richard S. Lehner, Brian T. O'Neill
  • Patent number: 5368567
    Abstract: This disclosure is directed to the design of a dilatation catheter having two or more associated fluidcarrying tubes, the operative or distal end of one of which supplies fluid to inflate an expansible balloon and the operable or distal end of the other of which supplies an injectable dye or contrast enhancing fluid adjacent the proximal end of the balloon.
    Type: Grant
    Filed: August 9, 1993
    Date of Patent: November 29, 1994
    Assignee: Schneider (USA) Inc.
    Inventor: Jeffrey A. Lee
  • Patent number: 5359370
    Abstract: Disclosed is an eyewear system designed to improve the comfort, fit, functionability, and modularity of the eyewear. Features include a 180.degree. reflex spring hinge which improves comfort, fit, and safety; a sway-hinge mechanism that allows the temples to be independently adjusted to improve comfort and fit of the eyewear behind the ears; a strap-pad which has been ergonomically designed to fit different shaped and sized noses and can be positioned for wearer comfort and convenience; a frame and lens construction that allows for modularity by the easy removal and replacement of the lens, temples, tops of frames, and nose pieces; and accessories that can be added to the eyewear to provide a greater degree of comfort and to protect the face from ultraviolet radiation and the wind.
    Type: Grant
    Filed: February 1, 1993
    Date of Patent: October 25, 1994
    Assignee: Mugnier Design
    Inventor: Marc Mugnier
  • Patent number: 5338846
    Abstract: A process for preparing a compounds of the formula ##STR1## or a pharmaceutically acceptable acid addition salt thereof, which comprises reacting a piperazine salt of the formula ##STR2## with an alkyl halide containing compound of the formula ##STR3## in water with a reagent to neutralize the hydrohalic acid and heating the mixture under conditions which are suitable to effect the coupling of said piperazine salt with said alkyl halide containing compound.
    Type: Grant
    Filed: April 20, 1993
    Date of Patent: August 16, 1994
    Assignee: Pfizer Inc.
    Inventors: Frank R. Busch, Paul Bowles, Douglas John, Meldrum Allen, Sabeto A. DiRoma, Dennis M. Godek
  • Patent number: 5338740
    Abstract: The present invention relates to novel heterocyclic derivatives of the formulaAr--W--Hetwherein Ar, W and Het are as defined below, and related compounds, pharmaceutical compositions comprising such compounds, and the use of such compounds as regulators of the action of angiotensin II in mammals. The compounds of this invention are useful in the treatment and prevention of hypertension, glaucoma, renal disease, congestive heart failure, cognitive dysfunction, and other conditions in which the action of angiotensin II is implicated. This invention also relates to pharmaceutical compositions containing these compounds and to methods of inhibiting angiotensin II in mammals by administration of such compounds.
    Type: Grant
    Filed: July 13, 1993
    Date of Patent: August 16, 1994
    Assignee: Pfizer Inc.
    Inventors: Philip C. Carpino, Ronald T. Wester, Paul A. Da Silva Jardine
  • Patent number: 5336771
    Abstract: The present invention relates to processes and intermediates for the preparation of spiro-heteroazolones. The latter compounds are useful as aldose reductase inhibitors.
    Type: Grant
    Filed: October 14, 1992
    Date of Patent: August 9, 1994
    Assignee: Pfizer Inc.
    Inventors: Charles W. Murtiashaw, George J. Quallich
  • Patent number: 5292749
    Type: Grant
    Filed: June 5, 1992
    Date of Patent: March 8, 1994
    Assignee: Pfizer Inc.
    Inventor: Alan Stobie
  • Patent number: 5270206
    Abstract: Process for the pancreatic lipase mediated transesterification method for the optical resolution of endo-norborneol; derived optically active 5-(3-(exo-bicyclo[2.2.1]hept-2-yloxy)-4-methoxyphenyl)-3,4,5,6-tetrahydrop yrimidin-2(1H)-ones; and stepwise process and intermediate therefor.
    Type: Grant
    Filed: May 8, 1992
    Date of Patent: December 14, 1993
    Assignee: Pfizer Inc.
    Inventor: Nicholas A. Saccomano
  • Patent number: 5231104
    Abstract: A series of novel 1-(phenethyl) and 1-(2-heteroarylethyl)-3-substituted piperidine derivatives have been prepared, including their pharmaceutically acceptable salts and various novel key intermediates therefor. The 3-substituent present in these compounds is an unsubstituted or substituted diphenylmethoxy group or a diphenylmethoxy-derived group, while the 1-substituent is unsubstituted or substituted phenethyl or 1-(2-heteroarylethyl) wherein the heteroaryl moiety is thienyl, pyridyl or pyrazinyl. These compounds in the form of both their racemates and 3R-isomers, are useful in therapy as smooth muscle muscarinic receptor antagonists and therefore, are of value in the treatment diseases associated with altered motility and/or smooth muscle tone.
    Type: Grant
    Filed: February 5, 1992
    Date of Patent: July 27, 1993
    Assignee: Pfizer Inc.
    Inventors: David Alker, Peter E. Cross, Robert M. Wallis
  • Patent number: D354971
    Type: Grant
    Filed: July 26, 1993
    Date of Patent: January 31, 1995
    Assignee: Mugnier Design
    Inventor: Marc Mugnier
  • Patent number: D355202
    Type: Grant
    Filed: July 26, 1993
    Date of Patent: February 7, 1995
    Assignee: Mugnier Design
    Inventor: Marc Mugnier
  • Patent number: D355203
    Type: Grant
    Filed: July 26, 1993
    Date of Patent: February 7, 1995
    Assignee: Mugnier Design
    Inventor: Marc Mugnier