Abstract: A method for destroying retinal pigment epithelial cells in an eye in order to prevent the occurrence of proliferative vitreoretinopathy. A solution containing a basement membrane binding agent conjugated to a cytotoxic agent is introduced into the vitreous chamber. The solution is maintained in the vitreous chamber for a period of time sufficient to permit the basement membrane binding agent to bind to basement membranes lining the vitreous chamber. The solution is then removed from the vitreous chamber, whereby a portion of the basement membrane binding agent remains bonded to basement membranes within the vitreous chamber, thereby exposing retinal pigment epithelial cells disposed on the basement membrane to the cytotoxic agent.

Abstract: A surface treated intraocular lens implant for use in the replacement of a cataracts natural lens to prevent posterior cellular opacification. The surface treated intraocular lens includes one or more carbohydrates covalently bound to the surface of the intraocular lens implant and a carbohydrate binding agent conjugated to a cytotoxic agent for binding said carbohydrates. The cytotoxic agent present on the intraocular lens implant serves to destroy residual lens epithelial cells within the lens capsule thereby preventing posterior cellular opacification of the intraocular lens implant.

Abstract: A method for destroying residual lens epithelial cells in an eye in order to prevent the occurrence of posterior chamber opacification. A solution containing a basement membrane binding agent conjugated to a cytotoxic agent is introduced into the lens capsule. The solution is maintained in the lens capsule for a period of time sufficient to permit the basement membrane binding agent to bind to basement membranes within the lens capsule. The solution is then removed from the lens capsule, whereby a portion of the basement membrane binding agent remains bonded to basement membranes within the lens capsule, thereby exposing residual lens epithelial cells disposed on the basement membrane to the cytotoxic agent.

Abstract: A method and apparatus for applying a lubricant coating to surgical needles utilizes a belt coating system with two endless belts. The endless belts have confronting running sides and are rotated in opposite directions for feeding the surgical needles therebetween. The needles are fed between the confronting running sides and are pressed lightly between the endless belts, whose surfaces have been wetted with the lubricant solution. The needles are cured after coating.

Abstract: This invention relates to materials for medical or veterinary use that possess considerably improved properties with regard to friction. The invention also relates to the production of such materials from existing materials that possess suitable bulk properties, but inappropriate frictional properties. This invention also relates to a hydrophilic coating material that provides improved frictional properties.

Abstract: A method for destroying residual lens epithelial cells in an eye in order to prevent the occurrence of posterior chamber opacification. A solution containing a basement membrane binding agent conjugated to a cytotoxic agent is introduced into the lens capsule. The solution is maintained in the lens capsule for a period of time sufficient to permit the basement membrane binding agent to bind to basement membranes within the lens capsule. The solution is then removed from the lens capsule, whereby a portion of the basement membrane binding agent remains bonded to basement membranes within the lens capsule, thereby exposing residual lens epithelial cells disposed on the basement membrane to the cytotoxic agent.

Abstract: A surgical fastener is comprised of a center span with two locking arms extending therefrom, each locking arm containing an indentation adapted to receive a locking point and an indentation adapted to receive a locking nub. An inner bendable member extends from the center span terminating in a staple point member, the staple point member terminating in a tissue piercing point. An outer bendable member extends from the staple point member parallel to the inner bendable member, terminating in a locking point and locking nub. In the closed position the locking point of the outer bendable member locks into the indentation in the locking arm, to lock the staple in the closed position. In the open position the locking nub of the outer bendable member locks into the locking nub indentation in the locking arm to hold the staple in the open position.

Abstract: An aqueous silicone coating composition containing a reactive siloxane polymer and a non-reactive dimethylpolysiloxane in an aqueous carrier having an effective amount of at least one dispersing agent to disperse the siloxanes throughout the aqueous carrier. Also provided is a method of lubricating substrates by applying an aqueous silicone coating composition to the substrate and curing the silicone thereon, as well as lubricated surgical needles prepared by that method.

Abstract: A method and apparatus for applying a lubricant coating to surgical needles utilizes a belt coating system with two endless belts. The endless belts have confronting running sides and are rotated in opposite directions for feeding the surgical needles therebetween. The needles are fed between the confronting running sides and are pressed lightly between the endless belts, whose surfaces have been wetted with the lubricant solution. The needles are cured after coating.

Abstract: This invention relates to materials for medical or veterinary use that possess considerably improved properties with regard to friction. The invention also relates to the production of such materials from existing materials that possess suitable bulk properties, but inappropriate frictional properties. This invention also relates to a hydrophilic coating material that provides improved frictional properties.

Abstract: A CDU hanger mount assembly and hanger is provided. The mount assembly and hanger allows the CDU to be supported by an object for supporting the CDU while the connecting point between the hanger mount and the pivot end of the hanger may be selectively moved from a point midway between the front and back of the CDU top toward the back of the CDU. This allows the CDU to be less displaced from the vertical upon displacing contact with an object such as a bedframe piece. The hanger and hanger mount assembly allows the alignment of the indicia on the CDU with the top surface of the material collected in the CDU to be a more accurate representation of the actual volume of material collected in the CDU. The mount assembly and hanger may also be used with medical devices other than CDUs.

Abstract: A guide wire feeding device for operation by a single hand of a physician is disclosed. The device includes an elastic locking ring which allows the guide wire to be fixed in relative position with the feeding device if desired.

Abstract: A diagnostic composition suitable for administration to a warm-blooded animal comprising somatostatin or a molecule capable of interacting with the somatostatin receptor labeled with a radionuclide by means of a chelate ligand capable of administration to an animal to produce reliable visual imaging of tumors or therapeutic effects on tumors.

Abstract: A diagnostic composition suitable for administration to a warm-blooded animal comprising hirudin or a molecule capable of interacting with the hirudin receptor labeled with a radionuclide by means of a chelate ligand capable of administration to an animal to produce reliable visual imaging of thrombus.

Abstract: The use of continuous deionization as an alternative or substitute method for the purification of a crude magnetic resonate.

Abstract: Methods and compositions for enhancing magnetic resonance imaging in at least a portion of a warm-blooded animal.