Patents Represented by Attorney Salvatore R. Conte
  • Patent number: 6177476
    Abstract: A method of replenishing plasmalogens in mammals comprising treatment with a plasmalogen-replenishing-effective amount of one or more stantially pure monoethers of glycerols and their carboxylic acid ester derivatives of Formula I: wherein R is a C12-C22 linear or branched alkyl or alkenyl group; and R1 and R2 are, each independently, hydrogen or an acyl moiety {—C(═O)—R3} wherein R3 is a linear or branched C1-C30 alkyl or alkenyl; and pharmaceutically-acceptable salts thereof, is disclosed. Nutritional supplements, dietary supplements and food additives comprising one or more substantially pure compounds of Formula I is also disclosed.
    Type: Grant
    Filed: August 27, 1998
    Date of Patent: January 23, 2001
    Assignee: Clarion Pharmaceuticals Inc.
    Inventors: Andrew C. Peterson, Thaddeus P. Pruss
  • Patent number: 5387688
    Abstract: Novel piperidinyl intermediates as set forth below wherein R, R.sup.1 and Ar are as set forth in the specification and W is either hydrogen or benzyloxycarbonyl. The intermediates are useful in the preparation of N-phenyl-N-(4-piperidinyl) amides having potent analgesic activity.
    Type: Grant
    Filed: December 11, 1992
    Date of Patent: February 7, 1995
    Assignee: Glaxo Inc.
    Inventors: Paul L. Feldman, Marcus F. Brackeen
  • Patent number: 5214148
    Abstract: N-Phenyl-N-(4-piperdinyl)amide derivatives are disclosed having the general formula (I): ##STR1## wherein X, Ar, R and R.sup.1 are defined, including isomeric forms thereof and acid addition salts thereof. The compounds exhibit analgesic activity. The invention embraces the compounds (I), pharmaceutical compositions of (I) and methods of providing analgesia with (I). Also included are certain novel intermediates for making (I).
    Type: Grant
    Filed: July 2, 1992
    Date of Patent: May 25, 1993
    Assignee: Glaxo Inc.
    Inventors: Paul L. Feldman, Marcus F. Brackeen
  • Patent number: 5130321
    Abstract: N-Phenyl-N-(4-piperdinyl)amide derivatives are disclosed having the general formula (I): ##STR1## wherein X, Ar, R and R.sup.1 are defined, including isomeric forms thereof and acid addition salts thereof. The compounds exhibit analgesic activity. The invention embraces the compounds (I), pharmaceutical compositions of (I) and methods of providing analgesia with (I). Also included are certain novel intermediates for making (I).
    Type: Grant
    Filed: December 18, 1990
    Date of Patent: July 14, 1992
    Assignee: Glaxo Inc.
    Inventors: Paul L. Feldman, Marcus F. Brackeen
  • Patent number: 5126455
    Abstract: A method of preparing certain substituted alkali metal 4-carboxy-piperidine salts (I) by alkaline hydrolysis of certain novel substituted 1,3,8-triazaspiro[4.5]decane-2, 4-diones (IV) which in turn are obtained from certain novel substituted chlorosulphonylamido piperidines (III).
    Type: Grant
    Filed: June 10, 1991
    Date of Patent: June 30, 1992
    Assignee: GLAXO Inc.
    Inventors: Paul L. Feldman, Marcus F. Brackeen
  • Patent number: 5039804
    Abstract: A method of preparing certain substituted alkali metal 4-carboxy-piperidine salts (I) by alkaline hydrolysis of certain novel substituted 1,3,8-triazaspiro[4.5]decane-2, 4-diones (IV) which in turn are obtained from certain novel substituted chlorosulphonylamido piperidines (III).
    Type: Grant
    Filed: December 13, 1989
    Date of Patent: August 13, 1991
    Assignee: Glaxo Inc.
    Inventors: Paul L. Feldman, Marcus F. Brackeen
  • Patent number: 5019583
    Abstract: N-Phenyl-N-(4-piperdinyl)amide derivatives are disclosed having the general formula (I): ##STR1## wherein X is a member selected from the group consisting of alkoxy-carbonyl-lower alkyl, lower alkyl-carbonyloxy-lower alkyl, alkenyloxy-carbonyl-lower alkyl, and (C.sub.1-2)alkoxy-(C.sub.1-2)-alkoxy-carbonyl-lower alkyl, and Ar, R, R.sup.1 and R.sup.2 are defined hereinafter, including isomeric forms thereof and acid addition salts thereof. The compounds exhibit analgesic activity having relatively short durations of analgesic action. The invention embraces the compounds (I), pharmaceutical compositions of (I) and methods of providing analgesia with (I). Also included are certain novel intermediates for making (I).
    Type: Grant
    Filed: December 11, 1989
    Date of Patent: May 28, 1991
    Assignee: Glaxo Inc.
    Inventors: Paul L. Feldman, Michael K. James, Marcus F. Brackeen, Michael R. Johnson, Harry J. Leighton
  • Patent number: 4778674
    Abstract: A pressurized aerosol composition containing zeolite, surfactant, water and propellant in prescribed amounts and ratios which, upon discharge from an aerosol container, produces a characteristically dry foam.
    Type: Grant
    Filed: May 28, 1986
    Date of Patent: October 18, 1988
    Assignee: Richardson-Vicks Inc.
    Inventors: Anil J. Gupte, Rodger E. Bogardus
  • Patent number: 4758630
    Abstract: Zinc and strontium unmixed partial salts of lower alkyl vinyl ether-maleic acid copolymers useful as denture adhesives.
    Type: Grant
    Filed: October 27, 1986
    Date of Patent: July 19, 1988
    Assignee: Richardson-Vicks Inc.
    Inventors: Nutan B. Shah, Michael C. Gounaris, Kenneth T. Holeva
  • Patent number: 4758432
    Abstract: Method and pharmaceutical composition for topically treating skin inflammatory disorders by administering to the inflamed area a therapeutically effective amount of candelilla wax or a saturated hydrocarbon fraction from candelilla wax comprising a mixture of saturated straight chain C.sub.29 -C.sub.33 hydrocarbons, predominantly C.sub.31 hydrocarbon.
    Type: Grant
    Filed: October 15, 1984
    Date of Patent: July 19, 1988
    Assignee: Richardson-Vicks Inc.
    Inventors: David Yeung, Eugene Gans, Sergio Nacht
  • Patent number: 4720353
    Abstract: A stable water-in-oil emulsion composition for topical therapeutic administration comprising:a. a dispersed aqueous phase comprising water optionally containing a pharmaceutically acceptable electrolyte dissolved therein;b. a pharmaceutically acceptable continuous oil phase comprising mineral oil and a volatile silicone fluid;c. an organopolysiloxane emulsifier of Formula (I) hereinafter described;d. PPG-20 Methyl Glucose Ether Distearate; ande. an active drug component for topical application.
    Type: Grant
    Filed: April 14, 1987
    Date of Patent: January 19, 1988
    Assignee: Richardson-Vicks Inc.
    Inventor: Stephen R. Bell
  • Patent number: 4705681
    Abstract: An improved hair treating or conditioning composition that decreases the friction between hairs thereby facilitating in combing and brushing of hair treated therewith contains a formulation which is a mixture of d-panthenyl ethyl ether and d-panthenol in a weight ratio of about 9 parts d-panthenol ethyl ester to about 1 part d-panthenol. Such hair treating or conditioning compositions also exhibit decreased damaged to hair treated therewith due at least in part to a decrease or reduction in abrasion between hairs.
    Type: Grant
    Filed: March 20, 1985
    Date of Patent: November 10, 1987
    Assignee: Richardson-Vicks Limited
    Inventors: Daniel Maes, Norman Brudney
  • Patent number: 4666716
    Abstract: Antidiarrheal compositions showing enhanced antidiarrheal activity comprise a non-steroidal anti-inflammatory drug compound and a polymeric hydroabsorptive agent. A patient in need of remedial or preventive treatment of diarrhea symptoms is administered an antidiarrheally effective amount of said antidiarrheal compositions.
    Type: Grant
    Filed: September 4, 1984
    Date of Patent: May 19, 1987
    Assignee: Richardson-Vicks Inc.
    Inventors: Bhogilal B. Sheth, Sheri A. Gilbert, Jane F. Kinsel
  • Patent number: 4656043
    Abstract: A stable aqueous hair conditioning shampoo composition comprising an aqueous solution of hydrogen peroxide, a specific anionic surfactant, at least one nonionic surfactant, an acidic pH-producing agent and one or more hair conditioning components.
    Type: Grant
    Filed: September 13, 1985
    Date of Patent: April 7, 1987
    Assignee: Richardson-Vicks Inc.
    Inventors: Geoffrey R. Hawkins, Oksana A. Kowcz
  • Patent number: 4626427
    Abstract: Preparation being effective against bad breath, particularly caused by strongly smelling food stuffs or cigarettes, alcohol and the like, consisting of cardamom seeds which are individually or jointly coated by a shell mass comprising a sugar mass or the like.
    Type: Grant
    Filed: September 16, 1985
    Date of Patent: December 2, 1986
    Assignee: Richardson-Vicks Inc.
    Inventors: Horst G. P. Wienecke, Karl-Wilhelm Stock
  • Patent number: 4623667
    Abstract: Method and pharmaceutical composition for topically treating skin inflammatory disorders by administering to the inflamed area a therapeutically effective amount of a substantially non-polar hydrocarbon fraction from beeswax comprising a mixture of (i) a major proportion of saturated straight chain C.sub.21 -C.sub.33 hydrocarbons and (ii) a minor proportion of mono-unsaturated long chain hydrocarbons.
    Type: Grant
    Filed: June 28, 1985
    Date of Patent: November 18, 1986
    Assignee: Richardson-Vicks Inc.
    Inventors: Eugene Gans, Sergio Nacht, David Yeung
  • Patent number: 4615739
    Abstract: An oil-in-water-in-oil coating composition comprising (a) an oil continuous phase comprising a solution of an oil soluble resin or drying oil or mixtures thereof in a water immiscible solvent, (b) an aqueous discontinuous phase comprising an emulsion with pH of about 4 to 10 of water insoluble resin in an aqueous medium, and (c) an effective dispersing amount of a dispersing agent for dispersing (b) in (a) consisting essentially of hydrated starch or a hydrated starch component.
    Type: Grant
    Filed: February 28, 1985
    Date of Patent: October 7, 1986
    Assignee: Formby's Inc.
    Inventors: Leonard R. Clark, Robert W. West
  • Patent number: 4612034
    Abstract: An improved herbicidal formulation comprising a mixture of the isopropylamine salt of glyphosate and an effective potentiating amount of an ammonium, quaternary alkyl ammonium, alkali metal or alkaline earth metal thiocyanate.
    Type: Grant
    Filed: November 28, 1983
    Date of Patent: September 16, 1986
    Assignee: J. T. Baker Chemical Company
    Inventors: Paul J. Kruger, George Schwartzkopf
  • Patent number: 4609674
    Abstract: A stabilized clear benzoyl peroxide composition is provided comprising from about 0.1 to about 3.8% by weight anhydrous benzoyl peroxide in C.sub.6 -C.sub.10 triglycerides.
    Type: Grant
    Filed: June 11, 1984
    Date of Patent: September 2, 1986
    Assignee: Richardson-Vicks Inc.
    Inventor: Anil J. Gupte
  • Patent number: 4606825
    Abstract: A method of separating and recovering immunoglobulin G from biological fluids by liquid chromatographic or solid phase extraction processes utilizing, as the solid phase, a carboxylated form of silica gel or controlled pore glass bearing non-cross-linked covalently bound polyethylenimine functions.
    Type: Grant
    Filed: April 22, 1985
    Date of Patent: August 19, 1986
    Assignee: J. T. Baker Chemical Company
    Inventors: Laura J. Crane, David R. Nau