Abstract: The present invention relates to a peptide comprising amino acids according to Formula (I): ((X)l(Y)m)n wherein l, m and n are integers from 0 to 10; X and Y, which may be the same or different, are an amino acid selected from the group consisting of hydrophobic amino acids and/or cationic amino acids, for use as a medicaments.

Abstract: An interventional catheter assembly comprising a catheter for insertion and guidance to a target site in a body lumen or a cavity and an operating head mounted in proximity to a distal end of the catheter and comprising a system for removing obstructive material from the target site is provided. In certain embodiments, the catheter assembly includes at least one aspiration port located proximal to the operating head that communicates with a first sealed lumen for withdrawing fluids and obstructive material from the target site, together with at least one liquid infusion port penetrating the catheter and located proximal to the at least one aspiration port that communicates with a second sealed lumen for supplying fluid to a location in proximity to the target site.

Abstract: Provided are methods, such as high throughput methods, of assessing or measuring the ability of an enzyme to modify the topology (e.g. supercoil topology) of a target nucleic acid, the methods comprising the steps of: (a) providing a solid support to which a capture nucleic acid is or may be immobilized, which capture nucleic acid is capable of binding the target nucleic acid in a manner that is proportional to the supercoil topology of said target nucleic acid (e.g. by triplex formation); (b) incubating a test mixture comprising (i) the enzyme, (ii) the target nucleic acid, (iii) capture nucleic acid, in the presence of (iv) said solid support, such that supercoiled target nucleic acid bound by the capture nucleic acid is immobilized to the solid support, (c) determining the amount of target nucleic acid bound by said capture nucleic acid in step (b) e.g. by use of a detectable label. The method may be used to screen for modulators of the enzyme activity.

Abstract: This invention relates to a screening method for the identification of agents which modulate the activity of a DNA replication protein as a target for intervention in cancer therapy and includes agents which modulate said activity. The invention also relates to the use of the DNA replication protein, and its RNA transcripts in the prognosis and diagnosis of proliferative disease e.g., cancer.

Abstract: Systems and methods for the generation of compost are provided. In one embodiment, the system for generating compost comprises a positively aerated floor, a semi gas and liquid impermeable compost cover sized to cover a compost biomass pile placed on the positively aerated floor, and a suction system positioned under or substantially close to the compost cover and generally near a top of the compost biomass pile, wherein the floor comprises a plurality of channels connected to at least one gas flow pipe installed below or above grade, wherein gas drawn by suction system at the top of the biomass compost pile maintains a negative pressure across the compost cover, thereby generating suction between the compost cover and the top of the compost biomass pile, and wherein the compost cover directs substantially all of the gas flow towards the suction system.

Abstract: A device for picking up solid material within a flexible bag is provided. The disclosed device comprises an outer body; an inner body substantially and slidably enclosed by the outer body; at least one spring mounted between the outer body and the inner body, wherein the inner and outer bodies each comprises an open end, wherein the inner body comprises an edge margin which is slidably protrudable from the open end of the outer body, wherein an elastic band is stretchably fittable around the protruding edge margin, wherein the outer body can be pushed downwards over the protruding edge margin of the inner body, causing the elastic band to be dislodged from the edge margin of the inner body.

Abstract: Systems and methods for noninvasive assessment of cardiac tissue properties and cardiac parameters using ultrasound techniques are disclosed. Determinations of myocardial tissue stiffness, tension, strain, strain rate, and the like, may be used to assess myocardial contractility, myocardial ischemia and infarction, ventricular filling and atrial pressures, and diastolic functions. Non-invasive systems in which acoustic techniques, such as ultrasound, are employed to acquire data relating to intrinsic tissue displacements are disclosed. Non-invasive systems in which ultrasound techniques are used to acoustically stimulate or palpate target cardiac tissue, or induce a response at a cardiac tissue site that relates to cardiac tissue properties and/or cardiac parameters are also disclosed.

Abstract: Crop protection compositions, formulated as powder, granules or water-based, of active compounds having foliar or systemic action are characterized in that they comprise, in the case of herbicide preparations, at least one herbicide from the groups of the urea derivatives or sulphonylureas, the carbamates, biscarbamates, diphenyl ethers, pyridolylacetic acid derivatives, pyridazines, triazines, triazinones, uracils, benzofuran derivatives, glyphosate or glufosinate, in the case of fungicide preparations, at least one fungicide from the group of the morpholines, azoles, phthalimides or piperidines, in the case of insecticide preparations, at least one insecticide from the group of the pyrethroids, carbamates or organophosphates, or possible salts or esters of the abovementioned groups of active compounds, at least one inorganic adsorbent and at least one surfactant, preferably from the group of the ethoxylated C6-to C20-alcohols, preferably C8- to C16-alcohols, the ethoxylated castor oils or the alkyl ether su

Abstract: An orthodontic bracket is provided. The bracket includes a rear wall coming to rest on a buccal or lingual tooth surface; and two guide surfaces running at right angles to one another, for guiding an archwire with a rectangular cross section, wherein the two guide surfaces are arranged distanced to the rear wall. A first gingival web runs below the first guide surface and at least one second occlusal web runs above the first guide surface, with a second passage being left free between the first web and the rear wall, and a first passage being left free between the second web and the rear wall.

Abstract: The invention relates to antigenic polypeptides expressed by pathogenic microbes, vaccines comprising said polypeptides; therapeutic antibodies directed to said polypeptides and methods to manufacture said polypeptides, vaccines and antibodies.

Abstract: A linear motor with an integrated guidance comprising a base plate comprising at least two side walls, and a travel plate guideably connected to the base plate in a linearly movable manner, wherein the travel plate comprises at least two rails and is connected to a plurality of rollers, wherein the plurality of rollers travel on the at least two rails.

Abstract: The present invention relates to antigenic polypeptides expressed by pathogenic microbes, including antigenic polypeptides encoded by the nucleic acid sequence of FIG. 1, vaccines comprising the antigenic polypeptides and therapeutic antibodies directed to the antigenic polypeptides.

Abstract: An oscillatory device incorporating a limited angle torque motor capable of oscillating one or more end effector(s) is provided. The device may additionally incorporate an ultrasound transducer and/or a waveguide structure.

Abstract: Isolated polynucleotides encoding polypeptides active in lignin, fructan and tannin biosynthetic pathways are provided, together with expression vectors and host cells comprising such isolated polynucleotides. Methods for the use of such polynucleotides and polypeptides are also provided.

Abstract: A nest and stack container system is provided. The system comprises a plurality of containers in various sizes, allowing the stacking of smaller sized containers on a larger sized container. Alternatively, the large container may be stacked on at least two adjacently-arranged small containers. The inventive nest and stack containers allow flexible handling of various sizes of storage containers. Individual containers can be stacked and nested among each other, and in combination, stacks of containers can be formed in any desired sequence of large and small containers, with individual containers each being placed in a slip-proof manner on top of another container.

Abstract: Novel isolated plant polynucleotide promoter sequences are provided, together with genetic constructs comprising such polynucleotides. Methods for using such constructs in modulating the transcription of DNA sequences of interest are also disclosed, together with transgenic plants comprising such constructs.

Abstract: An interventional catheter assembly has an operating head [400] and catheter system [300] that are inserted and navigated within a patient's body while an operator controls the system externally of the operating head. Fluidic communication is provided between the operating head and the external system controls, and rotation is provided to the operating head by means of an external drive system. Numerous system controls are provided, along with various operating systems, sealing assemblies, actuators, torque transfer systems, and the like are provided. Some systems and controls are provided in a control pod [200] and some controls, as well as displays, are provided in a console unit [100]. Control pod [200], catheter system [300] and operating head [400] may be provided as a sterile, single use interventional catheter system, while the console unit [100] may be provided as a multiple use device that communicates with the sterile, single use interventional catheter system during operation.

Abstract: Systems and methods for the generation of compost are provided. In one embodiment, the system for generating compost comprises an aeration floor having a plurality of gas flow apertures that connect to a network of gas flow channels, and a compost cover constructed of a gas and liquid impermeable fabric that is provided with a plurality of ports that permit the passage of gas and liquid through the compost cover. A compost biomass is placed on the aeration floor and the compost cover is placed over the compost biomass. An air suction manifold, connected to an outlet of the gas flow channels, draws exhaust gases from the compost biomass, through the plurality of gas flow apertures and through the gas flow channels. The exhaust gases are then conveyed to an air distributor and directed to an odor control device for substantially eliminating odors.