Patents Represented by Attorney, Agent or Law Firm William J. McNichol, Jr.
-
Patent number: 8293723Abstract: Inclusion compounds consisting of certain Angiotensin II AT1 receptors antagonist and cyclodextrins are described. These inclusion compounds are useful in the treatment of hypertension.Type: GrantFiled: December 23, 2010Date of Patent: October 23, 2012Assignee: Universidade Federal de Minas GeraisInventors: Ruben Dario Sinisterra Millan, Robson Augusto Souza Dos Santos, Frederic Jean Georges Frezard, Washington Xavier De Paula
-
Patent number: 7329641Abstract: The functional characteristics of heme proteins can be modified to produce hemoglobins that can be used as blood substitutes in different therapeutic applications. Stable polymers of tetrameric hemoglobin, and of myoglobin molecules, are provided for use in the blood substitutes.Type: GrantFiled: November 1, 2004Date of Patent: February 12, 2008Assignee: Temple University of the Commonwealth System of Higher EducationInventors: Clara Fronticelli, William S. Brinigar
-
Patent number: 6836613Abstract: A method of creating uniform adhesive layers in a planar optical display is disclosed. The method includes providing an adhesive reservoir, providing at least two optical panels, placing spacers between the optical panels, thereby forming a stack of optical panels having at least one uniform gap between adjacent ones of the optical panels, placing the stack into a panel reservoir having a height and a width, which panel reservoir is connected to the adhesive reservoir by a fluid path, and injecting adhesive from the adhesive reservoir through the fluid path into the bottom of the panel reservoir until each uniform gap is filled. A method of producing a black cladding layer having small particulate size for use in a planar optical display is also disclosed. The method includes providing black pigment having a fine particulate size of approximately 0.Type: GrantFiled: December 24, 2002Date of Patent: December 28, 2004Assignee: Brookhaven Science AssociatesInventors: Leonard DeSanto, Calvin Brewster
-
Patent number: 6832727Abstract: A display scanner includes an optical panel having a plurality of stacked optical waveguides. The waveguides define an inlet face at one end and a screen at an opposite end, with each waveguide having a core laminated between cladding. A projector projects a scan beam of light into the panel inlet face for transmission from the screen as a scan line to scan a barcode. A light sensor at the inlet face detects a return beam reflected from the barcode into the screen. A decoder decodes the return beam detected by the sensor for reading the barcode. In an exemplary embodiment, the optical panel also displays a visual image thereon.Type: GrantFiled: April 30, 1999Date of Patent: December 21, 2004Assignee: Brookhaven Science AssociatesInventor: James T. Veligdan
-
Patent number: 6825922Abstract: A system for measuring the external surface profile of a component using a non-contact optical technique which scans the field of view with a spot of light through a range of angles by utilizing a rotating mirror system and which precisely determines the angular position of the spot of light during scanning.Type: GrantFiled: September 26, 2003Date of Patent: November 30, 2004Assignee: Metron Systems, Inc.Inventors: Kyle S. Johnston, Joseph A. Franklin, Spencer G. Nelson, Charles M. Bass
-
Patent number: 6790869Abstract: Compositions and methods for prevention or treatment of disease are provided which comprise analogs of Resveratrol.Type: GrantFiled: May 18, 2001Date of Patent: September 14, 2004Assignee: Rutgers, The State University of New JerseyInventors: Geetha Ghai, Kuang Yu Chen, Robert T. Rosen, Mingfu Wang, Nitin Telang, Martin Lipkin, Chi-Tang H
-
Patent number: 6787160Abstract: A composition and method for delivering sulfur to skin and absorbing irritants in the skin. A high sorption base is employed which comprises non-swelling clay, gum, swelling clay, silicon and combinations thereof. The absorption of the irritants does not hinder the delivery of the active ingredient to the skin.Type: GrantFiled: December 20, 2002Date of Patent: September 7, 2004Assignee: Medicis Pharmaceutical CorporationInventors: Jonah Shacknai, Eugene H. Gans
-
Patent number: 6785007Abstract: A system and method for measuring the profile of an external surface of a part is provided. The system includes a source of light that directs light onto a region of the external surface of the part. The system also includes a linear, light-sensitive sensor, and a lens used to image locations within the region onto the sensor. The source of light and the sensor are located substantially within the same plane such that the sensor detects substantially only light scattered, diffracted, or reflected from the region and travelling substantially within the plane. The system additionally includes a re-positionable mirror that re-directs the light emitted from the source of light to the plurality of locations within the region and re-directs light scattered, diffracted, or reflected from the plurality of locations within the region to the lens and the sensor.Type: GrantFiled: June 27, 2002Date of Patent: August 31, 2004Assignees: Metron Systems, Inc., The Boeing CompanyInventors: Kyle S. Johnston, Tomas E. Lock, Thomas R. Clary, Spencer G. Nelson, Heath M. Greenberg
-
Patent number: 6782178Abstract: An optical panel is disclosed. A plurality of stacked planar optical waveguides are used to guide light from an inlet face to an outlet face of an optical panel. Each of the optical waveguides comprises a planar sheet of core material having a central plane. The core material has an index of refraction which decreases as the distance from the central plane increases. The decrease in the index of refraction occurs gradually and continuously.Type: GrantFiled: October 3, 2002Date of Patent: August 24, 2004Assignee: Brookhaven Science AssociatesInventor: James T. Veligdan
-
Patent number: 6765001Abstract: The present invention comprises a composition, method of enhancing potency and method of delivering corticosteroids in a vehicle comprising at least two penetration enhancers, and solvents and emulsifiers. The propylene glycol and penetration enhancers are present in ratio to the total of the propylene glycol, penetration enhancers, and solvents and emulsifiers of at least about 0.70.Type: GrantFiled: December 21, 2001Date of Patent: July 20, 2004Assignee: Medicis Pharmaceutical CorporationInventors: Eugene H. Gans, Mitchell S. Wortzman
-
Patent number: 6755534Abstract: A spatially modulated light beam is projected, reflected, and redirected through a prismatic optical panel to form a video image for direct viewing thereon.Type: GrantFiled: August 24, 2001Date of Patent: June 29, 2004Assignee: Brookhaven Science AssociatesInventors: James T. Veligdan, Leonard DeSanto, Calvin Brewster
-
Patent number: 6751019Abstract: An ultrathin mesh optical panel and a method of use and making are disclosed. One embodiment of the optical panel includes a plurality of optical waveguides, wherein each optical waveguide is formed of a mesh material surrounding an optically clear core. The optical panel further includes a light generator. Each optical waveguide internally reflects the light incoming at the inlet of the waveguide to the outlet of the waveguide. The optical panel may optionally include a light redirecting coupling layer and/or a diffuser. An alternate embodiment of the ultrathin optical panel includes a plurality of optical waveguides, wherein the mesh material serves as the light transmissive material. A method of making and using is applicable to both major embodiments. A modification of either embodiment is disclosed wherein the optical waveguide is aligned to be non-perpendicular to the panel face.Type: GrantFiled: June 11, 2001Date of Patent: June 15, 2004Assignee: Scram Technologies, Inc.Inventors: Leonard DeSanto, Calvin Brewster
-
Patent number: 6741779Abstract: An optical display panel which provides improved viewing contrast for front projection applications, and a method of producing a stacked optical waveguide panel for front projection applications, are disclosed. The optical panel includes a plurality of stacked optical waveguides, wherein each waveguide has a back face and an outlet face at opposing ends of each waveguide, and wherein each waveguide is formed of a core between an opposing pair of cladding layers, and at least one reflector connected to the back face of at least one waveguide, wherein the at least one reflector receives image light incident through at least one waveguide from the outlet face, and wherein the at least one reflector redirects the image light back through the at least one waveguide out of the outlet face. In the preferred embodiment, the outlet face is rendered black by inclusion of black within or between cladding layers.Type: GrantFiled: March 14, 2003Date of Patent: May 25, 2004Assignee: Scram Technologies, Inc.Inventor: James T. Veligdan
-
Patent number: 6719430Abstract: An ultrathin optical panel, and a method of producing an ultrathin optical panel, are disclosed, including stacking a plurality of glass sheets, which sheets may be coated with a transparent cladding substance or may be uncoated, fastening together the plurality of stacked coated glass sheets using an epoxy or ultraviolet adhesive, applying uniform pressure to the stack, curing the stack, sawing the stack to form an inlet face on a side of the stack and an outlet face on an opposed side of the stack, bonding a coupler to the inlet face of the stack, and fastening the stack, having the coupler bonded thereto, within a rectangular housing having an open front which is aligned with the outlet face, the rectangular housing having therein a light generator which is optically aligned with the coupler. The light generator is preferably placed parallel to and proximate with the inlet face, thereby allowing for a reduction in the depth of the housing.Type: GrantFiled: May 13, 2003Date of Patent: April 13, 2004Assignee: Scram Technologies, Inc.Inventors: Christopher T. Cotton, James T. Veligdan
-
Patent number: 6715886Abstract: An ultrathin optical panel, and a method of producing an ultrathin optical panel, are disclosed, including stacking a plurality of glass sheets, which sheets may be coated with a transparent cladding substance or may be uncoated, fastening together the plurality of stacked coated glass sheets using an epoxy or ultraviolet adhesive, applying uniform pressure to the stack, curing the stack, sawing the stack to form an inlet face on a side of the stack and an outlet face on an opposed side of the stack, bonding a coupler to the inlet face of the stack, and fastening the stack, having the coupler bonded thereto, within a rectangular housing having an open front which is aligned with the outlet face, the rectangular housing having therein a light generator which is optically aligned with the coupler. The light generator is preferably placed parallel to and proximate with the inlet face, thereby allowing for a reduction in the depth of the housing.Type: GrantFiled: April 25, 2002Date of Patent: April 6, 2004Assignee: Scram Technologies, Inc.Inventors: Christopher T. Cotton, James T. Veligdan
-
Patent number: 6704484Abstract: An optical system for projecting an image onto an input surface of a display to be observed by an observer at an output surface of the display is disclosed. The optical system comprises an image source, an imaging element, and a telescope. The optical system may also include a telecentric element and/or path-reduction prism. The display may comprise, for example, a plurality of stacked optical waveguides, each having a first end and a second end, wherein the input surface is defined by the plurality of first ends, and wherein the output surface is defined by the plurality of second ends. The optical system is preferably used when the tilt angle of the input surface is different than the tilt angle of the output surface. The optical system provides for a magnification to the input surface to be different than a magnification to the output surface.Type: GrantFiled: September 29, 2000Date of Patent: March 9, 2004Assignee: Scram Technologies, Inc.Inventor: Christopher T. Cotton
-
Patent number: 6685792Abstract: An optical panel having a small inlet, and a method of making a small inlet optical panel, are disclosed, which optical panel includes a individually coating, stacking, and cutting a first plurality of stacked optical waveguides to form an outlet face body with an outlet face, individually coating, stacking, and cutting a second plurality of stacked optical waveguides to form an inlet face body with an inlet face, and connecting an optical coupling element to the first plurality and second plurality of stacked optical waveguides, wherein the optical coupling element redirects light along a parallel axis of the inlet face to a parallel axis of the outlet face. In the preferred embodiment of the present invention, the inlet face is disposed obliquely with and askew from the outlet face.Type: GrantFiled: April 20, 2001Date of Patent: February 3, 2004Assignee: Brookhaven Science AssociatesInventors: James T. Veligdan, David E. Slobodin
-
Patent number: 6673065Abstract: A laser scalpel includes a ribbon optical waveguide extending therethrough and terminating at a slender optical cutting tip. A laser beam is emitted along the height of the cutting tip for cutting tissue therealong.Type: GrantFiled: July 31, 2000Date of Patent: January 6, 2004Assignee: Brookhaven Science AssociatesInventor: James T. Veligdan
-
Patent number: 6663856Abstract: Methods of inhibiting growth of cancer cells and treating cancer in a patient by administration of a vector expressing pRb2/p130 are provided.Type: GrantFiled: June 2, 1998Date of Patent: December 16, 2003Assignee: Thomas Jefferson UniversityInventor: Antonio Giordano
-
Patent number: D495485Type: GrantFiled: August 29, 2003Date of Patent: September 7, 2004Inventor: Benjamin D. Gordon