Abstract: A method, software, database, and system in which a query attribute is used as the basis for accessing stored attribute combinations and their frequencies of occurrence for individuals; and tabulating, based on frequencies of occurrence, those attribute combinations that are most likely to co-occur with the query attribute.
Type:
Grant
Filed:
October 3, 2022
Date of Patent:
April 4, 2023
Assignee:
23andMe, Inc.
Inventors:
Andrew Alexander Kenedy, Charles Anthony Eldering
Abstract: A method, software, database and system for attribute partner identification and social network based attribute analysis are presented in which attribute profiles associated with individuals can be compared and potential partners identified. Connections can be formed within social networks based on analysis of genetic and non-genetic data. Degrees of attribute separation (genetic and non-genetic) can be utilized to analyze relationships and to identify individuals who might benefit from being connected.
Type:
Grant
Filed:
May 13, 2022
Date of Patent:
March 7, 2023
Assignee:
23andMe, Inc.
Inventors:
Andrew Alexander Kenedy, Charles Anthony Eldering
Abstract: A system and method are presented in which known genetic attributes associated with a condition are used to seed the determination of additional attributes which are associated with the condition. Based on the learning, the additional attributes (genetic, behavioral, or both) provide for an increased correlation between the combined attributes and the condition. For behavioral attributes, a measure of the impact of the behavioral attribute on the risk of the condition can be transmitted to another device or system.
Type:
Grant
Filed:
October 4, 2018
Date of Patent:
February 14, 2023
Assignee:
23andMe, Inc.
Inventors:
Andrew Alexander Kenedy, Charles Anthony Eldering
Abstract: A method, software, database and system for attribute partner identification and social network based attribute analysis are presented in which attribute profiles associated with individuals can be compared and potential partners identified. Connections can be formed within social networks based on analysis of genetic and non-genetic data. Degrees of attribute separation (genetic and non-genetic) can be utilized to analyze relationships and to identify individuals who might benefit from being connected.
Type:
Grant
Filed:
April 26, 2022
Date of Patent:
February 14, 2023
Assignee:
23andMe, Inc.
Inventors:
Andrew Alexander Kenedy, Charles Anthony Eldering
Abstract: The present disclosure provides binding proteins, such as antibodies and antigen-binding fragments, which specifically bind to human CD96 receptor protein (hu-CD96) and are capable of decreasing, inhibiting, and/or fully-blocking immune regulatory effects mediated by hu-CD96. The present disclosure also provides methods of using the antibodies (and compositions thereof) to treat diseases and conditions responsive to decreasing, inhibiting and/or blocking immune regulatory function or activity mediated by CD96 binding to CD155, including effects arising from CD96 interactions with CD226 and/or TIGIT.
Type:
Grant
Filed:
December 18, 2019
Date of Patent:
January 17, 2023
Assignee:
23andMe, Inc.
Inventors:
Yu Chen, Chingwei Vivian Lee, Germaine Fuh-Kelly, Zuoan Yi, Yao-ming Huang, Valentine Yeung, Krista Maureen McCutcheon, Samuel Nalle, Augusta Eleanor Broughton, Louise Scharf, Navneet Singh, Tina Thai, Shouhua Xiao
Abstract: A method, software, database and system for attribute partner identification and social network based attribute analysis are presented in which attribute profiles associated with individuals can be compared and potential partners identified. Connections can be formed within social networks based on analysis of genetic and non-genetic data. Degrees of attribute separation (genetic and non-genetic) can be utilized to analyze relationships and to identify individuals who might benefit from being connected.
Type:
Grant
Filed:
February 15, 2021
Date of Patent:
January 3, 2023
Assignee:
23andMe, Inc.
Inventors:
Andrew Alexander Kenedy, Charles Anthony Eldering
Abstract: Displaying an indication of ancestral data is disclosed. An indication that a genetic interval corresponds to a reference interval that has a likelihood of having one or more ancestral origins is received. One or more graphic display parameters are determined based at least in part on the indication. An indication of the one or more ancestral origins is visually displayed using the one or more graphic display parameters.
Type:
Grant
Filed:
February 28, 2022
Date of Patent:
December 20, 2022
Assignee:
23andMe, Inc.
Inventors:
John Michael Macpherson, Brian Thomas Naughton, Joanna Louise Mountain
Abstract: Ancestry deconvolution includes obtaining unphased genotype data of an individual; phasing, using one or more processors, the unphased genotype data to generate phased haplotype data; using a learning machine to classify portions of the phased haplotype data as corresponding to specific ancestries respectively and generate initial classification results; and correcting errors in the initial classification results to generate modified classification results.
Type:
Grant
Filed:
January 28, 2021
Date of Patent:
December 6, 2022
Assignee:
23andMe, Inc.
Inventors:
Chuong Do, Eric Durand, John Michael Macpherson
Abstract: The disclosed embodiments concern methods, apparatus, systems and computer program products for determining and displaying pedigrees based on IBD data. Some implementations use a probabilistic relationship model to obtain various likelihoods of various potential relationships based on pairwise IBD data and pairwise age data. Some implementations build large pedigrees by combining smaller pedigrees. Some implementations display pedigree graphs with various features that are informative and easy to understand.
Type:
Grant
Filed:
September 11, 2020
Date of Patent:
November 29, 2022
Assignee:
23andMe, Inc.
Inventors:
Ethan M. Jewett, Andrew C. Seaman, Kimberly F. McManus, William A. Freyman, Cordell T. Blakkan, Adam Auton, Joanna L. Mountain, Susan M. Furest, Rachel E. Lopatin, Hang Xu, Hilary M. Vance
Abstract: A method, software, database and system for attribute partner identification and social network based attribute analysis are presented in which attribute profiles associated with individuals can be compared and potential partners identified. Connections can be formed within social networks based on analysis of genetic and non-genetic data. Degrees of attribute separation (genetic and non-genetic) can be utilized to analyze relationships and to identify individuals who might benefit from being connected.
Type:
Grant
Filed:
April 28, 2022
Date of Patent:
November 29, 2022
Assignee:
23andMe, Inc.
Inventors:
Andrew Alexander Kenedy, Charles Anthony Eldering
Abstract: An embodiment may involve storing, by a computing device and in a database, a set of pangenetic attributes of a set of individuals, wherein the pangenetic attributes of the set are respectively and statistically associated with products; based on the statistical associations between the pangenetic attributes and the products, determining, by the computing device, product recommendations for a second set of individuals; receiving, by the computing device and from the second set of individuals, a plurality of measures of satisfaction with the product recommendations; based on the plurality of measures of satisfaction, learning, by the computing device, an association between a subset of the pangenetic attributes and a particular product; and storing, by the computing device and in the database, the learned association, wherein the learned association provides a basis for subsequent recommendations of the particular product when a subsequent individual exhibits the subset of the pangenetic attributes.
Type:
Grant
Filed:
March 25, 2021
Date of Patent:
November 29, 2022
Assignee:
23andMe, Inc.
Inventors:
Andrew Alexander Kenedy, Charles Anthony Eldering
Abstract: A method, software, database and system for determining an optimal treatment for an illness in an individual and for determining the impact (e.g., side effects and intended benefits) of the treatment in the individual are presented in which an attribute profile of the individual containing genetic and non-genetic attributes is compared against a database containing combinations genetic and non-genetic attributes that are statistically associated with successful treatment of the illness in other individuals.
Abstract: Determining relative relationships of people who share a common ancestor within at least a threshold number of generations includes: receiving recombinable deoxyribonucleic acid (DNA) sequence information of a first user and recombinable DNA sequence information of a plurality of users; processing, using one or more computer processors, the recombinable DNA sequence information of the plurality of users in parallel; determining, based at least in part on a result of processing the recombinable DNA information of the plurality of users in parallel, a predicted degree of relationship between the first user and a user among the plurality of users, the predicted degree of relative relationship corresponding to a number of generations within which the first user and the second user share a common ancestor.
Type:
Grant
Filed:
January 14, 2022
Date of Patent:
November 22, 2022
Assignee:
23andMe, Inc.
Inventors:
Lawrence Hon, Serge Saxonov, Brian Thomas Naughton, Joanna Louise Mountain, Anne Wojcicki, Linda Avey
Abstract: A method, software, database and system for attribute partner identification and social network based attribute analysis are presented in which attribute profiles associated with individuals can be compared and potential partners identified. Connections can be formed within social networks based on analysis of genetic and non-genetic data. Degrees of attribute separation (genetic and non-genetic) can be utilized to analyze relationships and to identify individuals who might benefit from being connected.
Type:
Grant
Filed:
April 28, 2022
Date of Patent:
November 8, 2022
Assignee:
23andMe, Inc.
Inventors:
Andrew Alexander Kenedy, Charles Anthony Eldering
Abstract: A method, software, database, and system in which a query attribute is used as the basis for accessing stored attribute combinations and their frequencies of occurrence for individuals; and tabulating, based on frequencies of occurrence, those attribute combinations that are most likely to co-occur with the query attribute.
Type:
Grant
Filed:
July 26, 2022
Date of Patent:
October 25, 2022
Assignee:
23andMe, Inc.
Inventors:
Andrew Alexander Kenedy, Charles Anthony Eldering
Abstract: Inferring a characteristic of an individual is disclosed. An indication that a first user and a second user have at least one shared chromosomal segment is received. Information about the second user is obtained. A characteristic of the first user is inferred based at least in part on the information about the second user.
Type:
Grant
Filed:
October 22, 2020
Date of Patent:
October 11, 2022
Assignee:
23andMe, Inc.
Inventors:
John Michael Macpherson, Brian Thomas Naughton, Joanna Louise Mountain
Abstract: A method, software, database and system for attribute partner identification and social network based attribute analysis are presented in which attribute profiles associated with individuals can be compared and potential partners identified. Connections can be formed within social networks based on analysis of genetic and non-genetic data. Degrees of attribute separation (genetic and non-genetic) can be utilized to analyze relationships and to identify individuals who might benefit from being connected.
Type:
Grant
Filed:
January 26, 2022
Date of Patent:
May 31, 2022
Assignee:
23andMe, Inc.
Inventors:
Andrew Alexander Kenedy, Charles Anthony Eldering