Patents Assigned to Ajou University Industry-Academic Cooperation Foundation
  • Publication number: 20230248263
    Abstract: Provided are a method, apparatus and system for prediction of a neonatal brain development prognosis. The computing device includes a memory; and at least one processor performing communication with the memory, wherein the processor is configured to extract cerebral blood flow (CBF) and brain tissue relaxation times T1 and T2 from the input magnetic resonance imaging (MRI) of a subject newborn; generate brain neurodevelopment prediction data of the subject newborn using a pregenerated brain neurodevelopment prediction model; and control the output of the generated brain neurodevelopment prediction data of the subject newborn.
    Type: Application
    Filed: December 27, 2022
    Publication date: August 10, 2023
    Applicants: THE CATHOLIC UNIVERSITY OF KOREA INDUSTRY-ACADEMIC COOPERATION FOUNDATION, AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
    Inventors: Hyun Gi KIM, Jang Hoon LEE
  • Publication number: 20230211461
    Abstract: The present invention relates to a surface treatment method for dental zirconia, including sandblasting the surface of three types of dental zirconia (3Y-TZP, 4Y-PSZ and 5Y-PSZ) with alumina particles, and this method optimizes sandblasting conditions for each type of zirconia and enhances mechanical properties by strengthening residual stress. In addition, a dental article including dental zirconia made by the surface treatment method for zirconia, and suitable protocols for the durable bond between resin cements and high-translucent zirconia are suggested.
    Type: Application
    Filed: November 29, 2022
    Publication date: July 6, 2023
    Applicant: AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
    Inventor: Hee-Kyung KIM
  • Patent number: 11691880
    Abstract: The present embodiments relate to a method for manufacturing a two-dimensional material using a top-down method, the method includes the steps of preparing a bulk crystal, forming a metal layer on the bulk crystal, and then attaching a thermal release tape on the metal layer, exfoliating a two-dimensional material to which the metal layer and the thermal release tape have been attached from the bulk crystal, transferring the two-dimensional material to which the metal layer and the thermal release tape have been attached onto a substrate, and removing the thermal release tape and the metal layer from the substrate onto which the two-dimensional material has been transferred.
    Type: Grant
    Filed: July 29, 2021
    Date of Patent: July 4, 2023
    Assignee: AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
    Inventors: Jaehyun Lee, Jiyun Moon
  • Patent number: 11692227
    Abstract: A method of screening a skin whitening agent uses the stromal cell-derived factor 1 (SDF1) promoter region, the correlation between the expression amount of the skin pigment and the expression of the SDF1 promoter is observed and thus it is expected to be available in systems for pre-screening pigmentation substances and pigment reduction materials, and the drugs screened by the method is used for treatment of skin pigment-related diseases.
    Type: Grant
    Filed: July 17, 2019
    Date of Patent: July 4, 2023
    Assignee: AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
    Inventors: Hee Young Kang, Tae Jun Park, Jung Eun Yoon
  • Patent number: 11692019
    Abstract: The present invention relates to a heterodimeric Fc-fused protein comprising a first Fc region and a second Fc region of an immunoglobulin Fc pair and a physiologically active protein composed of two or more different subunits, wherein one or more subunits of the physiologically active protein are linked separately to one or more ends of the N-terminus or C-terminus of the first Fc region and/or the second Fc region, and CH3 domains of the first Fc region and the second Fc region are mutated so as to promote the heterodimeric Fc formation. Moreover, the present invention relates to a pharmaceutical composition comprising the heterodimeric Fc-fused protein.
    Type: Grant
    Filed: May 28, 2020
    Date of Patent: July 4, 2023
    Assignee: Ajou University Industry-Academic Cooperation Foundation
    Inventors: Yong Sung Kim, Keunok Jung, Ji Hee Ha, Dong Ki Choi, Hye Ji Choi, Ye Jin Kim
  • Publication number: 20230203661
    Abstract: The present invention relates to an apparatus and method for forming a silicon nitride film by performing plasma enhanced atomic layer deposition (PE-ALD) employing very high frequency (VHF). An atomic layer deposition apparatus according to an embodiment of the present invention may comprise: a chamber providing a space in which a process is performed; a substrate support unit for supporting a substrate in the chamber; a gas supply unit for supplying gas to the chamber; an exhaust unit for discharging gas in the chamber; a plasma generation unit installed in the chamber to generate plasma in the chamber; and a VHF (very high frequency) power source for applying a VHF band signal to the plasma generation unit.
    Type: Application
    Filed: December 28, 2022
    Publication date: June 29, 2023
    Applicant: AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
    Inventors: Il Kwon OH, Min-Jeong RHEE
  • Publication number: 20230200683
    Abstract: A self-tilt training apparatus according to an exemplary embodiment of the present disclosure includes a storage unit which stores a daily training setting value including a training tilt angle and a training time of a patient, a first sensor unit which includes a plurality of sensors in close contact with the patient and measures the tilt angle of the patient and a motion of the patient, a control unit which determines whether the patient stands up according to the set training tilt angle at the time of starting the training and whether the patient maintains the tilt angle during the training time on the basis of the daily training setting value and the measurement values of the first sensor unit, and an output unit which outputs a message, through any one or more manners of sight, touch, and hearing, according to a direction of the control unit.
    Type: Application
    Filed: May 7, 2021
    Publication date: June 29, 2023
    Applicant: AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
    Inventors: Jun Young CHOI, Tae Joon KIM
  • Patent number: 11684793
    Abstract: The present invention relates to a non-thermal atmospheric-pressure plasma keloid treatment device and a use thereof. The non-thermal atmospheric-pressure plasma keloid treatment device according to the present invention has effects of inhibiting collagen deposition in keloid fibroblasts and mobility thereof, and thus, is expected to be greatly useful for preventing and treating keloids.
    Type: Grant
    Filed: July 27, 2018
    Date of Patent: June 27, 2023
    Assignee: AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
    Inventors: Chul Ho Kim, Sung Un Kang
  • Publication number: 20230197466
    Abstract: Disclosed is a plasma etching method. The plasma etching method comprises: a first step for evaporating liquid perfluoropropyl carbinol (PPC); a second step for supplying a discharge gas including the evaporated PPC and argon gas to a plasma chamber in which an object to be etched is arranged; and a third step for discharging the discharge gas to generate plasma, and using the plasma to plasma-etch the object to be etched.
    Type: Application
    Filed: March 2, 2021
    Publication date: June 22, 2023
    Applicant: AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
    Inventors: Chang-Koo KIM, Jun-Hyun KIM
  • Publication number: 20230190522
    Abstract: The present invention provides a device for diagnosing and treating ocular deviation, comprising: an eye mask which is worn by an examinee, and in which an eye movement capturing means for capturing the eye movement of the examinee is provided; a temperature-regulating pipe which is inserted into the ear of the examinee and which increases or decreases the temperature inside the ear of the examinee; a heat source supply part for supplying a heat source to the temperature-regulating pipe from the outside in order to increase and decrease the temperature of the temperature-regulating pipe; a fixing main body which is worn by the examinee, and which has a mounting hole, in which the temperature-regulating pipe is mounted, in order to fix the temperature-regulating pipe inserted into the ear of the examinee; and a control part, which is connected to the eye movement capturing means and the heat source supply part, receives an image of the eye captured by the eye movement capturing means, and extracts center coord
    Type: Application
    Filed: May 18, 2021
    Publication date: June 22, 2023
    Applicant: AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
    Inventor: Ji Man HONG
  • Publication number: 20230181922
    Abstract: The present invention provides a nasal disease treatment aid device, comprising: a nose cover which forms a dome so as to cover the nose of a user and covers the nose while being positioned on the nose of the user; a fixing member which is connected to the left and right sides of the nose cover and fixed to the head of the user so that the nose cover is fixed to the nose of the user; insertion members having, interposed therebetween, a support body provided in the inner space of the nose cover and extending outward from the left and right sides of the support body and are formed in tubular shapes each having a hollow inside that communicates back and forth so as to allow the user to breathe through the nostrils; LED light sources which are provided on one side of each of the insertion members and irradiate therapeutic light into the inside of the nose; and low-frequency stimulation units which are provided on each of the left and right sides of the nose cover and physically stimulate paranasal sinuses while i
    Type: Application
    Filed: May 4, 2021
    Publication date: June 15, 2023
    Applicant: AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
    Inventor: In Su PARK
  • Publication number: 20230184147
    Abstract: Disclosed herein is a meta-muffler for reducing broadband noise. The meta-muffler includes: a flow pipe through which a fluid flows; an outer barrel disposed outside the flow pipe to be spaced apart from the flow pipe; and multiple metastructures arranged in a flow direction of the fluid and each comprising an opening opened parallel to the flow direction of the fluid, a resonance chamber disposed between the flow pipe and the outer barrel and communicating with the flow pipe through the opening, and a neck adjustment member extending from the outer barrel toward the flow pipe to be spaced apart from the opening in the flow direction of the fluid. The meta-muffler can increase transmission loss of noise flowing through the flow pipe through maximization of energy loss of sound waves entering the resonance chamber of the metastructure and can effectively attenuate noise over a wide band ranging from low frequencies to high frequencies.
    Type: Application
    Filed: February 6, 2023
    Publication date: June 15, 2023
    Applicants: CENTER FOR ADVANCED META-MATERIALS, AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
    Inventors: Byung Hun AN, Jin Woo LEE, Hak Joo LEE
  • Publication number: 20230189650
    Abstract: Provided is a preparation method for a thermoelectric composite. The preparation method for a thermoelectric composite comprises the steps of: preparing a base substrate containing a first binary metal oxide; and providing a metal precursor and a reaction material containing oxygen (O) onto the base substrate to form a material film containing a second biliary metal oxide resulting from the reaction of the metal precursor and the reaction material, wherein in the step of forming the material film, a 2-dimensional electron gas is generated between the base substrate and the material film as the material film is formed on the base substrate.
    Type: Application
    Filed: February 2, 2023
    Publication date: June 15, 2023
    Applicants: Industry-University Cooperation Foundation Hanyang University Erica Campus, Ajou University Industry-Academic Cooperation Foundation
    Inventors: Tae Joo Park, Sang Woon Lee, Dae Woong Kim, Tae Jun Seok, Jae Hyun Yoon, Ji Hyeon Choi
  • Publication number: 20230174579
    Abstract: The present invention relates to a composition for preventing or treating Behcet’s disease and rheumatoid arthritis, the composition containing a peptide or a mixture thereof as an active ingredient. More specifically, an intraperitoneal injection or application of P1 to P5 peptides or a mixture thereof as a skin external preparation to a mouse animal model having Behcet’s disease caused by autoimmune response was found to ameliorate skin ulcers and skin inflammation in the Behcet’s disease mouse model, and an arthritis amelioration effect on a rheumatoid arthritis animal model was also observed. Accordingly, the composition containing P1 to P5 peptides or mixtures thereof as active ingredients can be provided as medicine for Behcet’s disease and rheumatoid arthritis.
    Type: Application
    Filed: December 4, 2020
    Publication date: June 8, 2023
    Applicant: AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
    Inventor: Seonghyang SOHN
  • Publication number: 20230178341
    Abstract: A plasma etching method is disclosed. The plasma etching method comprises: a first step for vaporizing liquid pentafluoropropanol (PFP); a second step for supplying discharge gas comprising the vaporized PFP and argon gas into a plasma chamber in which an object to be etched is placed; and a third step for discharging the discharge gas to generate plasma and etching the object by using the plasma.
    Type: Application
    Filed: March 2, 2021
    Publication date: June 8, 2023
    Applicant: AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
    Inventors: Chang-Koo KIM, Jun-Hyun KIM
  • Patent number: 11666604
    Abstract: Disclosed are a multilayered cell sheet of cardiac stem cells (CSCs) and a method of manufacturing the same. In particular, the present disclosure provides a method of manufacturing a multilayered cell sheet according to a single step culture procedure by using, as a three-dimensional matrix, a biodegradable natural polymer hydrogel and embedding CSCs in the hydrogel. The multilayered cell sheet of the present disclosure does not require any special device for the manufacturing, is manageable with good physicomechanical property, increases a cell engraftment rate after transplantation based on sufficient accumulation of various growth and protective factors and extracellular matrix between cells, and is also self-assembled by the cell-mediated hydrogel compaction, making nutrients transfer easy. Therefore, the multilayered cell sheet of the CSCs is expected to be usefully applicable as a therapeutic agent for myocardium regeneration.
    Type: Grant
    Filed: December 18, 2017
    Date of Patent: June 6, 2023
    Assignees: INJE UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION, AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
    Inventors: Young-Il Yang, Ki-Dong Park, Won-Jin Lee, Min-Young Choi, Kyung-Min Park, Yun-Ki Lee
  • Publication number: 20230167034
    Abstract: Provided is a surface treatment method for dental zirconia, which includes sandblasting the surfaces of three types of dental zirconia (3Y-TZP, 4Y-PSZ and 5Y-PSZ) with alumina particles, and when sandblasting conditions are optimized for each type of zirconia, the microstructure destruction of a subsurface layer may be minimized and compressive stress may be reinforced by a phase change, thereby improving mechanical properties, and the penetration of resin cement through microcracks inhibits crack propagation and thus is advantageous in increasing bonding efficiency of dental zirconia. In addition, a dental article including dental zirconia made by the surface treatment method for zirconia, and clinically suitable sandblasting protocols are provided.
    Type: Application
    Filed: November 29, 2022
    Publication date: June 1, 2023
    Applicant: AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
    Inventor: Hee-Kyung KIM
  • Patent number: 11661927
    Abstract: A driving device includes a first driving element and a first flexible structure. The first driving element includes a first wire extending in a first direction and includes a shape memory alloy. The first flexible structure has a certain width in a second direction perpendicular to the first direction, and when the first wire contracts in the first direction, the first flexible structure has a height increasing in a third direction perpendicular to both the first direction and the second direction. The driving device further includes a second driving element including a second wire and a second flexible structure, the second wire extending in the first direction and including a shape memory alloy. The second flexible structure has a certain width in the second direction, and when the second wire contracts in the first direction, the second flexible structure has a height increasing in the third direction.
    Type: Grant
    Filed: September 17, 2021
    Date of Patent: May 30, 2023
    Assignees: SAMSUNG ELECTRONICS CO., LTD., AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
    Inventors: Bongsu Shin, Jesung Koh, Hongseok Lee, Dongjin Kim, Baekgyeom Kim
  • Patent number: 11654903
    Abstract: A moving object escape prevention method includes: controlling, by a processor of a moving object, to drive the moving object based on autonomous driving; detecting, by the processor, whether a collision occurred by the moving object; in response to detecting the collision, transmitting, by the processor, a collision occurrence notification signal and position information of the moving object to an Intelligent Transportation System Infrastructure (ITSI); receiving, by the processor, escape-related information from the ITSI. The receiving escape-related information includes: determining, by the ITSI, whether or not the moving object escapes based on position information of the moving object; receiving, by the processor, accident handling information from the ITSI upon determining that the moving object does not escape, and receiving, by the processor, an escape warning message from the ITSI when the position information of the moving object changes.
    Type: Grant
    Filed: January 27, 2021
    Date of Patent: May 23, 2023
    Assignees: HYUNDAI MOTOR COMPANY, KIA MOTORS CORPORATION, AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
    Inventors: Jae Jun Ha, Ilsoo Yun, Sangmin Park, Sungho Park, Harim Jeong, Cheolwoo Kwon, Jiwon Kim, Kiyeon Park
  • Publication number: 20230142077
    Abstract: The present invention relates to a method for preventing or treating angiogenesis-related diseases using a liquid type plasma. More specifically, the present invention relates to a method for preparing a liquid type plasma for preventing or treating angiogenesis-related diseases, a pharmaceutical composition for preventing or treating angiogenesis-related diseases using a liquid type plasma prepared by the method, and a method for preventing or treating angiogenesis-related diseases using the liquid type plasma.
    Type: Application
    Filed: October 17, 2022
    Publication date: May 11, 2023
    Applicant: AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
    Inventors: Chul Ho KIM, Sung Un KANG