Abstract: The compound (7R,8R,9R)-2,3-Dimethyl-8-hydroxy-7-(2-methoxyethoxy)-9-phenyl-7,8,9,10-tetrahydro-imidazo-[1,2-h] [1,7] naphthyridine inhibits the secretion of gastric acid.
Abstract: Compounds of a certain formula (I), in which R1, R2, R3, R4, R5 and X have the meanings indicated in the description, are novel effective compounds with anti-proliferative and/or apoptosis inducing activity.
Type:
Application
Filed:
January 26, 2006
Publication date:
May 29, 2008
Applicant:
ALTANA PHARMA AG
Inventors:
Matthias Vennemann, Thomas Bar, Jurgen Braunger, Petra Gimmnich, Thomas Beckers, Mathias Schmidt, Thomas Ciossek, Sandra Nappe
Abstract: Compounds of a certain formula (I), in which R1, R2, R3, R31, R4, R5, R51 and Har have the meanings indicated in the description, are novel effective PDE4 inhibitors.
Type:
Application
Filed:
January 31, 2006
Publication date:
May 22, 2008
Applicant:
ALTANA Pharma AG
Inventors:
Ulrich Kautz, Beate Schmidt, Dieter Flockerzi, Maria Vittoria Chiesa, Armin Hatzelmann, Christof Zitt, Johannes Barsig, Andrea Wohlsen, Degenhard Marx, Hans-Peter Kley
Abstract: The invention provides compounds of the formula (I) in which the substituents and symbols are as defined in the description. The compounds inhibit the secretion of gastric acid.
Type:
Application
Filed:
December 6, 2005
Publication date:
May 22, 2008
Applicant:
Altana Pharma AG
Inventors:
Christof Brehm, Wilm Buhr, M. Vittoria Chiesa, Andreas Palmer, Peter Jan Zimmermann, Wolfgang-Alexander Simon, Stefan Postius, Wolfgang Kromer
Abstract: The invention is directed to processes for preparing cyclic benzimidazoles, which compounds have gastric secretion inhibiting and excellent gastric and intestinal protective action properties.
Abstract: The invention provides compounds of the formula (I) in which the substituents and symbols are as defined in the description. The compounds inhibit the secretion of gastric acid.
Type:
Application
Filed:
October 13, 2005
Publication date:
May 15, 2008
Applicant:
Altana Pharma AG
Inventors:
Wilm Buhr, Peter Jan Zimmermann, Christof Brehm, Adreas Palmer, M.Vittoria Chiesa, Wolfgang-Alexander Simon, Stefan Postius, Wolfgang Kromer, Georg Rast, Udo Doelling
Abstract: Compounds of a certain formula (I), in which Ra and Rb have the meanings indicated in the description, are novel effective compounds with anti-proliferative and apoptosis inducing activity.
Type:
Application
Filed:
February 8, 2006
Publication date:
April 24, 2008
Applicant:
ALTANA Pharma AG
Inventors:
Klaus Pekari, Mathias Schmidt, Thomas Bar, Thomas Beckers, Bjorn Bartels
Abstract: The compounds of formula (I) in which R1, R2, R3, R4 and R11 have the meanings as given in the description are novel effective iNOS inhibitors.
Abstract: The invention provides compounds of the formula 1, in which the substituents and symbols are defined in the description. The compounds inhibit the secretion of gastric acid.
Abstract: The invention relates to compounds of the formula 1, in which R1, R2, R3, Arom and PG have the meanings as indicated in the description. These compounds are valuable intermediates for the preparation of pharmaceutically active compounds.
Abstract: The present invention relates to 8-substituted imidazopyridines of a certain formula (1) in which the substitutents and symbols have the meanings indicated in the description. The compounds have gastric secretion inhibiting and excellent gastric and intestinal protective action properties.
Type:
Grant
Filed:
November 15, 2003
Date of Patent:
February 5, 2008
Assignee:
Altana Pharma AG
Inventors:
Wilm Buhr, Jörg Senn-Bilfinger, Peter Jan Zimmermann
Abstract: The invention relates to compounds of the formula (1) where the substituents and symbols are as defined in the description. The compounds are valuable intermediates for preparing active pharmaceutical ingredients.
Type:
Grant
Filed:
February 12, 2003
Date of Patent:
January 1, 2008
Assignee:
Altana Pharma AG
Inventors:
Wilm Buhr, Jörg Senn-Bilfinger, Peter Jan Zimmerman, Peter Zimmerman
Abstract: The invention relates to compounds of the formula (1) wherein the substituents and symbols have the meanings indicated in the description. The compounds have gastric acid secretion inhibiting and excellent gastric and intestinal protective action properties.
Abstract: The invention relates to cyclic benzimidazoles of formula 1, in which the substituents and symbols have the meanings indicated in the description. The compounds have gastric secretion inhibiting and excellent gastric and intestinal protective action properties.
Type:
Grant
Filed:
April 2, 2004
Date of Patent:
December 11, 2007
Assignee:
Altana Pharma AG
Inventors:
Wilm Buhr, M. Vittoria Chiesa, Peter Jan Zimmermann