Abstract: The invention relates to 6,7,8,9-Tetrahydro-3H-imidazo[4,5-h]quinolines of formula 1, in which the substituents and symbols have the meanings indicated in the description. The compounds have gastric secretion inhibiting and excellent gastric and intestinal protective action properties.
Abstract: The present invention relates to the field of pharmaceutical technology and describes a novel advantageous preparation for an active ingredient. The novel preparation is suitable for producing a large number of pharmaceutical dosage forms. In the new preparation an active ingredient is present essentially uniformly dispersed in an excipient matrix composed of one or more excipients selected from the group of fatty alcohol, triglyceride, partial glyceride and fatty acid ester.
Type:
Grant
Filed:
December 6, 2001
Date of Patent:
February 13, 2007
Assignee:
Altana Pharma AG
Inventors:
Rango Dietrich, Rudolf Linder, Hartmut Ney
Abstract: Novel surfactant protein C esters suitable for preparing pharmaceutical compositions for the treatment of infant respiratory distress syndrome and adult respiratory distress syndrome are described.
Abstract: The invention relates to the use of certain proton pump inhibitors in the treatment of pathological manifestations induced or influenced by free radicals.
Abstract: A compliance monitor (20) is attachable to or forms part of a drug delivery device, such as an inhaler (2). The monitor comprises a flexible portion (38) to enable a switch which is actuated by a user when delivering a dose of medicament. The monitor further comprises a sensor for sensing whether the device is properly positioned in contact with or relative to the user's body for administration of the medicament. For example, where the device is an inhaler and the sensor a temperature sensor, temperature variations caused by insertion of an inhaler mouthpiece into the user's mouth indicate whether the dose has been delivered into the patient's mouth. A memory in the compliance monitor stores a compliance record indicating whether or not the device was properly positioned each time a dose was delivered.
Type:
Application
Filed:
September 22, 2004
Publication date:
February 1, 2007
Applicant:
Altana Pharma AG
Inventors:
Robert Jongejan, Antje-Henriette Fink-Wagner, Christopher Ferris
Abstract: The compounds of formula (I) in which R1, R2, R3, R4 and R11 have the meanings as given in the description are novel effective iNOS inhibitors.
Abstract: The compounds of Formula (I) in which R1, R2, R3, R4, R5 and A have the meanings as given in the description are novel effective iNOS inhibitors.
Abstract: The invention relates to pharmaceutical compositions containing combinations of salmeterol and ciclesonide and the use of such pharmaceutical compositions in medicine, in particular, the prophylaxis and treatment of respiratory disease.
Abstract: The invention relates to the use of certain known PIDE4 inhibitors for the treatment of diabetes mellitus and accompanying disorders thereof.
Abstract: A rapidly disintegrating tablet for oral administration of acid-labile active ingredients is described. The rapidly disintegrating tablet for oral administration of an acid-labile active ingredient comprises a plurality of individual active ingredient units together with pharmaceutical excipients, where the acid-labile active ingredient is present in the individual active ingredient units in a matrix composed of a mixture comprising at least one solid paraffin and one or more substances from the group of fatty alcohol, triglyceride and fatty acid ester, and where excipients which, on oral intake of the tablet, bring about rapid disintegration of the tablet are present.
Type:
Grant
Filed:
December 6, 2001
Date of Patent:
December 12, 2006
Assignee:
Altana Pharma AG
Inventors:
Rango Dietrich, Hartmut Ney, Rudolf Linder
Abstract: The invention relates to compounds of the formula (I), in which the substituents and symbols have the meanings indicated in the description. The compounds are valuable intermediates for the preparation of pharmaceutical active compounds.
Abstract: The invention relates to imidazopyridines of a certain formula 1, in which the substituents and symbols have the meanings indicated in the description. The compounds have gastric secretion-inhibiting properties.
Type:
Grant
Filed:
May 24, 2004
Date of Patent:
November 28, 2006
Assignee:
Altana Pharma AG
Inventors:
Jörg Senn-Bilfinger, Wilm Buhr, Peter Zimmermann, Bernhard Kohl
Abstract: The compounds of formula I in which R1 is 1–4C-alkoxy, A is 1–4C-alkylene, B represents 3H-imidazo[4,5-b]pyridin-2-yl, 3H-imidazo[4,5-b]pyridin-2-yl substituted by R2 and/or R3, 9H-purin-8-yl or 9H-purin-8-yl substituted by R4 and/or R5, are effective iNOS inhibitors.
Abstract: Recombinant surfactant protein A and pharmaceutical compositions based thereon are useful for the prevention or treatment of pulmonary infection and inflammation.
Type:
Grant
Filed:
January 18, 2000
Date of Patent:
November 14, 2006
Assignee:
Altana Pharma AG
Inventors:
Wolfram Steinhilber, Jeffrey A. Whitsett, Ann Marie Levine, Thomas R. Korfhagen
Abstract: The invention relates to the 1,5-naphthalene disulfonic acid addition salt of the compound of the formula 1, or a solvate or hydrate thereof. The compound according to the invention is a valuable intermediate for the preparation of therapeutically active compounds.
Type:
Application
Filed:
May 13, 2004
Publication date:
October 19, 2006
Applicant:
Altana Pharma AG
Inventors:
Peter Zimmermann, Christian Scheufler, Bernhard Kohl
Abstract: Compounds of formula (1) in which the substituents have the meanings mentioned in the description, are suitable for the prevention and treatment of gastrointestinal diseases.
Abstract: Compounds of the formula I, in which M, A1, A2, K1 and K2 have the meanings given in the description are novel effective tryptase inhibitors.