Patents Assigned to Arizona Board of Regents
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Patent number: 11952379Abstract: This invention is in the field of medicinal pharmacology. In particular, the invention relates to a new class of small-molecules having a pyrazino-pyrimidine-dione (or related) structure which function as modulators (activators, inhibitors) of protease activated receptor type 2 (PAR2), and their use as therapeutics for the treatment of conditions involving PAR2 activity (e.g., asthma, chronic pain, cancer and/or vascular disorders).Type: GrantFiled: April 9, 2019Date of Patent: April 9, 2024Assignees: Arizona Board of Regents on Behalf of the University of Arizona, Board of Regents, The University of Texas SystemInventors: Scott A. Boitano, Josef Vagner, Theodore J. Price, Greg Dussor
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Patent number: 11952637Abstract: Provided herein are methods and compositions for rapid, highly sensitive detection of SARS-CoV-2 in biological samples. In particular, provided herein is a rapid, low-cost method for detecting SARS-CoV-2 that provides reliable, visible test results and does not require PCR reagents, elaborate biosafety precautions, or sophisticated laboratory equipment.Type: GrantFiled: June 11, 2021Date of Patent: April 9, 2024Assignees: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY, THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTOInventors: Alexander Green, Keith Pardee, Margot Karlikow, Kaiyue Wu, Masoud Norouzi
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Patent number: 11950026Abstract: A light projection system including a light source and a light controller to generate modulatable beams of light and an angular light modulator (ALM) positioned to selectively direct the light from each beam. The light controller can be a spatial light modulator or a processor programmed to control light output. The angular light modulator may be a digital micromirror device (DMD). The ALM may be configured to direct the images into diffraction orders or using scanning the images. A LIDAR system to detect a position of an object including a first source of a two-dimensional array of beams of light and ALM to project light into a selected one of a plurality of directions. An illumination system, comprising a first angular-spatial light modulator (ASLM) and a second ASLM system configured such a first beam and a second beam of light intersect.Type: GrantFiled: April 13, 2018Date of Patent: April 2, 2024Assignee: ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONAInventors: Yuzuru Takashima, Brandon Hellman, Braden Smith
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Patent number: 11944967Abstract: Sub-micrometer bioparticles are separated by size in a microfluidic channel utilizing a ratchet migration mechanism. A structure within the microfluidic channel includes an array of micro-posts arranged in laterally shifted rows. Reservoirs are disposed at each end of the microfluidic channel. A biased AC potential is applied across the channel via electrodes immersed into fluid in each of the reservoirs to induce a non-uniform electric field through the microfluidic channel. The applied potential comprises a first waveform with a first frequency that induces electro-kinetic flow of sub-micrometer bioparticles in the microfluidic channel, and an intermittent superimposed second waveform with a higher frequency. The second waveform selectively induces a dielectrophoretic trapping force to selectively impart ratchet migration based on particle size for separating the sub-micrometer bioparticles by size in the microfluidic channel.Type: GrantFiled: November 12, 2021Date of Patent: April 2, 2024Assignee: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITYInventors: Alexandra Ros, Daihyun Kim, Jinghui Luo
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Patent number: 11945107Abstract: A method of controlling a drive motor for a powered ankle exoskeleton is disclosed. The method includes modeling motor drive current as a linear function of desired torque and ankle angular velocity, and then controlling motor current as a function of measured torque and determined ankle angular velocity.Type: GrantFiled: March 19, 2021Date of Patent: April 2, 2024Assignee: ARIZONA BOARD OF REGENTS ON BEHALF OF NORTHERN ARIZONA UNIVERSITYInventors: Zachary Forest Lerner, Greg Orekhov, Jason Luque
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Patent number: 11945985Abstract: Compounds of General Formula I may harvest electrogenerated excitons via metal-assisted delayed fluorescence (MADF). The compounds have utility in light emitting diodes and light emitting devices.Type: GrantFiled: May 11, 2021Date of Patent: April 2, 2024Assignee: Arizona Board of Regents on behalf of Arizona State UniversityInventors: Jian Li, Jiang Wu
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Patent number: 11947128Abstract: A gaze tracking platform for human-machine interface device, such as a wearable Augmented Reality Near-to-Eye Display. The gaze tracking method, digital illumination assisted analog feedback tracking employs neither auxiliary camera nor digital image processing of human eye image that confronts challenges in gaze tracking speed, power, cost and space. Instead, an analog-digital hybrid method to track the gaze inspired by the groove tracking method that is widely adopted for optical data storage systems. In the method, a digital micromirror device generates angular modulated and infrared illuminating beam. The cornea reflects the infrared light and a segmented photodiode detects the reflection while providing a feedback servo signal to the digital micromirror device controller. The feedback signal is integrated over a time provides the variation gaze. Moreover, infrared and angularly modulated illumination is time-multiplexed with information displayed in visible wavelength.Type: GrantFiled: September 14, 2020Date of Patent: April 2, 2024Assignee: ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONAInventor: Yuzuru Takashima
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Publication number: 20240103908Abstract: Provided herein are dynamic adaptive scheduling (DAS) systems. In some embodiments, the DAS systems include a first scheduler, a second scheduler that is slower than the first scheduler, and a runtime preselection classifier that is operably connected to the first scheduler and the second scheduler, which runtime preselection classifier is configured to effect selective use of the first scheduler or the second scheduler to perform a given scheduling task. Related systems, computer readable media, and additional methods are also provided.Type: ApplicationFiled: September 19, 2023Publication date: March 28, 2024Applicants: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY, WISCONSIN ALUMNI RESEARCH FOUNDATION, UNIVERSITY OF ARIZONA, BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEMInventors: Chaitali CHAKRABARTI, Umit OGRAS, Ahmet GOKSOY, Anish KRISHNAKUMAR, Ali AKOGLU, Md Sahil HASSAN, Radu MARCULESCU, Allen-Jasmin FARCAS
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Publication number: 20240099602Abstract: A system and associated methods for accurate localization of seizure onset zone (SOZ) from independent components (IC) of resting state functional magnetic resonance imaging (rs-fMRI) to improve surgical outcomes in children with Drug Resistant Epilepsy (DRE) are disclosed. The system and methods define a phased approach, where fMRI noise-related biomarkers are used through high fidelity image processing techniques to eliminate noise ICs. Then SOZ markers are used through a maximum likelihood-based classifier to determine SOZ localizing ICs.Type: ApplicationFiled: September 25, 2023Publication date: March 28, 2024Applicant: Arizona Board of Regents on Behalf of Arizona State UniversityInventors: Ayan Banerjee, Sandeep Gupta, Varina Boerwinkle
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Patent number: 11937561Abstract: Modular cultivation systems utilized in a Vertical Farm or Plant Factory is described herein. The modular cultivation system has a growing module that includes an expandable and collapsible support frame with growing boards or pods, lighting boards, and an irrigation system arranged within the support frame to maximize the quantity of crops that can be grown within an available volume of space in a Vertical Farm unit, warehouse or greenhouse per unit time. The modular cultivation system further includes a mover robot for moving the growing module. The Vertical Farm relies on an ambulatory cultivation system and a cyclical automated operational protocol for planting, growing and harvesting made possible by the ambulatory growing module. Thus, access for crop planting, maintenance and harvesting is conveniently carried out through automation, that is, by commanding a specific ambulatory cultivation system to move autonomously to designated locations in the vertical farm.Type: GrantFiled: February 24, 2021Date of Patent: March 26, 2024Assignee: ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONAInventors: Joel L. Cuello, Yaser Mehdipour, Jack Welchert
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Publication number: 20240095425Abstract: Systems and methods are provided for predicting microhardness properties of a weld that defines a weld joint between at least two workpieces. The system includes a processor programmed to: receive temperature data that includes temperature values each attributed to a corresponding one of a plurality of points of the weld at corresponding times during a welding process used to produce the weld, determine peak temperature values and cooling rate values for each of the points of the weld based on the temperature values, predict a three-dimensional (3D) distribution of microhardness values of the weld based on a machine learning method that evaluates the peak temperature values and the cooling rate values, and generate display data based on the 3D distribution of microhardness values.Type: ApplicationFiled: September 20, 2022Publication date: March 21, 2024Applicants: GM GLOBAL TECHNOLOGY OPERATIONS LLC, Arizona Board of Regents on behalf of Arizona State UniversityInventors: Ying Lu, Junjie Ma, Hui-ping Wang, Mitchell Poirier, Baixuan Yang, Jay Oswald
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Publication number: 20240091309Abstract: Synthetic antimicrobial peptides, compositions comprising thereof, and methods of use for modulating one or more symptoms of an infection in a subject are disclosed. In some aspects, the infection is caused by mycobacteria, for example, a nontuberculous mycobacterium such as Mycobacterium abscessus. In other aspects, the infection is caused by Escherichia coli, Pseudomonas aeruginosa, or methicillin-resistant Staphylococcus aureus (MRSA). Also disclosed are methods of identifying synthetic antimicrobial peptides against a pathogen with no known effective treatment using a library of synthetic peptides.Type: ApplicationFiled: September 11, 2023Publication date: March 21, 2024Applicant: Arizona Board of Regents on Behalf of Arizona State UniversityInventors: Shelley HAYDEL, Christopher DIEHNELT
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Publication number: 20240096490Abstract: A processor is configured to implement a machine learning model that is trained to select transcripts in blood for distinguishing neurodegenerative diseases. The algorithm is developed via machine learning and leverages concepts associated with blood-based changes in mRNA gene expression for differentiating patients of any neurodegenerative disease regardless of the proteins or their post-translational modifications occurring in disease.Type: ApplicationFiled: January 28, 2022Publication date: March 21, 2024Applicant: Arizona Board of Regents on Behalf of Arizona State UniversityInventors: Carol J. Huseby, Paul Coleman
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Publication number: 20240096047Abstract: Based on traffic images characteristics, a general pre-processing system and method reduces input size of neural network object recognition models to focus on necessary regions. The system includes a light neural network (binary or low precision; based on configuration) to detect target regions for further processing and applies a deeper model to those specific regions. The present disclosure provides experimentation results on various types of methods, such as conventional convolutional neural networks, transformers, and adaptive models, to show the scalability of the system.Type: ApplicationFiled: September 1, 2023Publication date: March 21, 2024Applicant: Arizona Board of Regents on Behalf of Arizona State UniversityInventors: Mohammad Farhadi, Yezhou Yang, Rahul Santhosh Kumar Varma
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Publication number: 20240095528Abstract: A method for increasing the temperature-resiliency of a neural network, the method comprising loading a neural network model into a resistive nonvolatile in-memory-computing chip, training the deep neural network model using a progressive knowledge distillation algorithm as a function of a teacher model, the algorithm comprising injecting, using a clean model as the teacher model, low-temperature noise values into a student model and changing, now using the student model as the teacher model, the low-temperature noises to high-temperature noises, and training the deep neural network model using a batch normalization adaptation algorithm, wherein the batch normalization adaptation algorithm includes training a plurality of batch normalization parameters with respect to a plurality of thermal variations.Type: ApplicationFiled: September 8, 2023Publication date: March 21, 2024Applicant: Arizona Board of Regents on behalf of Arizona State UniversityInventors: Jae-sun Seo, Jian Meng, Li Yang, Deliang Fan
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Publication number: 20240096073Abstract: A consensus-based decentralized multi-robot approach is presented for reconstructing a discrete distribution of features, modeled as an occupancy grid map, that represent information contained in a bounded planar 2D environment, such as visual cues used for navigation or semantic labels associated with object detection. The robots explore the environment according to a random walk modeled by a discrete-time discrete-state (DTDS) Markov chain and estimate the feature distribution from their own measurements and the estimates communicated by neighboring robots, using a distributed Chernoff fusion protocol. Under this decentralized fusion protocol, each robot's feature distribution converges to the ground truth distribution in an almost sure sense.Type: ApplicationFiled: September 11, 2023Publication date: March 21, 2024Applicant: Arizona Board of Regents on behalf of Arizona State UniversityInventors: Aniket Shirsat, Spring Berman, Shatadal Mishra, Wenlong Zhang
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Publication number: 20240091092Abstract: Systems and methods for a wearable “exo-shell” to improve the gait of elderly people during obstacle avoidance tasks are disclosed. With payload and energy expenditure as a main focus of this design, the present system leverages switchable, passive systems, in combination with lightweight materials that minimize additional metabolic costs, while remaining as “transparent” to the user as possible when inactive.Type: ApplicationFiled: June 6, 2023Publication date: March 21, 2024Applicant: Arizona Board of Regents on Behalf of Arizona State UniversityInventors: Daniel Aukes, Dongting Li
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Patent number: 11935843Abstract: Systems for physical unclonable function (“PUF”) generation, PUF devices, and methods for manufacturing PUF devices. In one implementation, the system includes a plurality of PUF devices and an electronic controller. Each of the plurality of PUF devices include a first electrochemically-inactive electrode, a second electrochemically-inactive electrode, and a layer of silicon suboxide. The layer of silicon suboxide is positioned directly between the first electrochemically-inactive electrode and the second electrochemically-inactive electrode. The electronic controller is communicably coupled to the plurality of PUF devices. The electronic controller is configured to read binary values associated with the plurality of PUF devices.Type: GrantFiled: December 4, 2020Date of Patent: March 19, 2024Assignee: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITYInventor: Michael Kozicki
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Patent number: 11932739Abstract: Composite material can include a matrix material, a fiber dispersed in the matrix material, and an ultraviolet (UV)-light sensitive mechanophore grafted to a surface of the fiber. A method for making a fiber-reinforced polymer composite can include contacting a fiber in a first solution, rinsing and then drying intermediate fiber, contacting dried fiber in a third solution, rinsing, and then drying the rinsed fiber thereby generating functionalized fiber that is sensitive to ultraviolet light. The functionalized fiber can be combined with a polymer matrix material, cured, and irradiated, thereby generating a fiber-reinforced polymer composite.Type: GrantFiled: November 16, 2021Date of Patent: March 19, 2024Assignee: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITYInventors: Ryan Gunckel, Lenore Dai, Aditi Chattopadhyay, Bonsung Koo
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Patent number: 11936782Abstract: The performance of quantum key distribution by systems and methods that use wavelength division multiplexing and encode information using both wavelength and polarization of photons of two or more wavelengths. Multi-wavelength polarization state encoding schemes allow ternary-coded digits, quaternary-coded digits and higher-radix digits to be represented by single photons. Information expressed in a first radix can be encoded in a higher radix and combined with a string of key values to produce a datastream having all allowed digit values of that radix in a manner that allows eavesdropping to be detected without requiring the sender and receiver to exchange additional information after transmission of the information.Type: GrantFiled: February 1, 2023Date of Patent: March 19, 2024Assignee: ARIZONA BOARD OF REGENTS ON BEHALF OF NORTHERN ARIZONA UNIVERSITYInventors: Bertrand F. Cambou, Ines Montano, Ryan Behunin, Vince Rodriguez