Abstract: A disposable kit for a medical apparatus includes a tray and a subassembly with sections foldably connected to each other. At least one of the sections can fold itself onto the tray so that the subassembly encloses a region of the tray. When the tray is laid on the subassembly in a predetermined position, elevated channel regions formed on a front side of the tray and facing the subassembly can accommodate component installations of the subassembly, and a section of the subassembly can be folded to the rear side of the tray so that component installations on that section can be accommodated in elevated channel regions formed on the rear side of the tray. In this manner, the subassembly forms a hard-shell that at least partially surrounds the tray and protects pre-installed or packed pressure-sensitive components, parts and or regions of the disposable kit.

Abstract: A machine for extracorporeal blood treatment including a housing for accommodating operational components of the machine for extracorporeal blood treatment and a light-emitting unit having no diffusion disk for displaying an operating and/or therapy condition of the machine according to the principle of ambient light. The light-emitting unit is arranged in a predetermined sequence and/or with predetermined shaping on at least one portion of the housing. The light-emitting unit is a flexible light conductor having at least one end-face light coupling surface at a first end and at least one end-face light output surface at a second end or alternatively a self-luminous flat and/or flexible OLED unit.

Abstract: A method for extracorporeal blood treatment using a medical device including at least a dialyzer device, with the following steps: start of blood treatment by means of hemodialysis on the basis of default values for the hemodialysis; determination of current values or ratios of at least one blood flow, an ultrafiltration quantity, a substitution quantity or a type of substitution; recording of a therapy progress on the basis of an output signal of a sensor means; determination of a time of formation of a secondary membrane on the dialyzer by determination of a cross rate in the dialyzer device; change from the hemodialysis to a hemodiafiltration with post-dilution after a predetermined period of time has elapsed; and regulation of the substitution quantity during hemodiafiltration with post-dilution. Corresponding tools for carrying out the method are arranged in a device for extracorporeal blood treatment.

Abstract: A hose mount of a blood treatment machine, having a hose connection element as a component of the machine's internal hosing including at least one rigid sleeve portion that is adapted to position a flexible hose radially outside over the free end of the at least one sleeve portion, an axial stop formed or arranged on the outer circumference of the sleeve portion at a distance from the free end, and a flexible collar arranged or formed on the at least one sleeve element toward the free end with an axial distance to the axial stop in order to define an external circumferential groove between itself and the axial stop.

Abstract: A method and device for linearizing an optical sensor in a dialysis apparatus. The method includes introducing a sensor to the dialysate-side drain line, determining the linear range of the optical sensor, backwards extrapolating the data from the linear range and correcting the data from the non-linear range.

Abstract: Methods of combined sterilization and integrity testing of dialyzers such as hollow fiber dialyzers are disclosed. Sterilization and integrity testing may be performed by treating the dialyzer with a sterilization fluid for sterilizing at least the blood-side compartment of the dialyzer and for wetting the dialysis membrane of the dialyzer with the sterilization fluid, and carrying out an integrity testing of the dialysis membrane wetted with the sterilization fluid, wherein the sterilization fluid is selected from aqueous solutions containing peroxide and/or ozone, the peroxide being selected from peroxides which disintegrate into water, oxygen and/or volatile organic compounds, and from aqueous solutions containing chlorine, bromine and/or iodine.

Abstract: A sterile filter module/dialyzer packaging including a filter module, preferably a dialyzer, sterile-packaged in a primary packaging. The filter module having an essentially cylindrical central section and a filter module connection formed at the end of the central section. The primary packaging is a blister packaging with a plastic molded part as a lower section forming a receiving compartment for the filter module and a soft upper foil which, with the lower section, closes the receiving compartment for the filter module. The upper foil is fixed onto the lower section so as to be hermetically sealed and the filter module is fixed at least in sections by means of form fit.

Abstract: A device for extracorporeal blood treatment, in particular a dialysis machine, including a peristaltic pump for conveying fluid from a low-pressure side to a high-pressure side, the peristaltic pump comprising a rotor which is rotatable around a rotor axis and a support area which is formed around the rotor axis in an arcuate manner, with an elastically deformable fluid line being able to be positioned between the rotor and the support area and being deformed between the rotor and the support area with rotation of the rotor while forming a cross-sectional constriction, so that upon rotation of the rotor with respect to the support area a fluid in the fluid line is conveyed from the low-pressure side to the high-pressure side. The device includes a machine housing part realized as a formed sheet metal part, wherein the support area is formed in the machine housing part by plastic deformation.

Abstract: A dialysis machine with machine-internal fluidics for dialysis fluid and a housing that at least partially encapsulates the fluidics, wherein the fluidics comprise an input line for fresh dialysis fluid to a dialyzer and an output line for used dialysis fluid from the dialyzer, each line equipped at their end sides with a connection port for a releasably coupling with the dialyzer, wherein the port of the input line and the port of the output line are each formed as a coupling integrated into the housing.

Abstract: Tamperproof closures for use on a container are disclosed. The closure includes a base which can be arranged on a container port and can be connected thereto in a fluid-tight manner as well as a closure part connected to the base via a predetermined breaking point. Each of the base and the closure part includes at least one force-enhancing means by which a movement of the base and the closure part relative to each other can be force-assisted in terms of destruction of the predetermined breaking point. The movement of the base and the closure part relative to each other can be a rotary movement of the closure part with respect to the base in the opening direction of the closure part and each force-enhancing means can be a handle in the form of a lever projecting radially from both the base and the closure part with respect to the axis of rotation of the rotary movement.

Abstract: The invention relates to a medical device for extracorporeal blood treatment comprising an extracorporeal blood circulation having at least one tube and at least two sensor units measuring on the tube with different operating principles, wherein portions of the tube are adapted to be coupled to the at least two sensor units for measurement. According to the invention, each sensor unit consists of a sensor-specific component and a sensor-neutral component, wherein the sensor-neutral components of the sensor units are formed to be identical whereas the sensor-specific components are different in response to the operating principle and comprise a respective specific sensor system.

Abstract: Methods and systems for identifying a malfunction in the extracorporeal blood circulation of a dialysis machine are disclosed. The malfunction may be identified by detecting at least one state parameter; determining a first evaluation criterion for identifying a malfunction in the extracorporeal blood circulation (FEB); using the first evaluation criterion, making a decision with respect to the presence of a malfunction in the extracorporeal blood circulation, generating a first error signal, and monitoring the detected state parameter; determining at least one further evaluation criterion; using the at least one further evaluation criterion, making a decision with respect to the presence of a malfunction in the extracorporeal blood circulation and generating at least one further error signal; combining the first error signal and the at least one further error signal to result in a combined error signal; and triggering an alarm if the combined error signal exceeds a predetermined limit value.

Abstract: Apparatus and control methods for determining a distribution volume of at least one uremic substance in a dialysis patient are disclosed. The apparatus may include a dialyzer, an optional flow rate measuring system for detecting the flow rate of a dialysis fluid through the dialyzer, a dialysis fluid measuring system for detecting at least one dialysis fluid parameter that depends on the at least one substance in the dialysis fluid, and a computer for establishing a dialysis dose based on the dialysis fluid parameter and for establishing the distribution volume based on the dialysis dose taking a clearance factor and dialysis duration into account.

Abstract: A detecting device for a medium inside a tube portion comprises at least one light source being arranged at a first position relative to the tube portion adapted to be transilluminated with light and being configured to irradiate light onto the tube portion, a detector unit being arranged at a second position relative to the tube portion and being configured to receive light from the at least one light source passed through the tube portion and to analyze a medium inside the tube portion in a spatially resolving manner, and a homogenizing device being arranged at a position between the at least one light source and the tube portion and being configured, for detecting and quantifying differences in brightness due to local differences of the medium inside the tube portion, to create a homogenous and/or isotropic distribution of the light from the at least one light source before the light enters into the tube portion.

Abstract: The invention concerns a device for extra-corporal blood treatment, including an extra-corporal blood circulation for the pumping of blood, where individual components of the extra-corporal blood circulation are inside and outside of a casing of the device, and a base socket is attached below the casing, which includes a collection trough in which liquids leaking inside the casing can be collected. The device has a sensor with which the presence of liquid within the collection trough is measurable. The device includes receptacle resources for the reception of leaking liquids occurring outside of the casing, where the receptacle resources are developed so that, above a specified quantity, they route leaking liquids into the collection trough.

Abstract: A connector for connecting a dialyzer to a fluid-carrying line is disclosed, wherein the connector includes a coupling portion, especially a male Hansen connector portion, for fluid-tight connection to a connector element, especially a female Hansen connector adapter, of the line. In a flow channel of the connector, a shut-off device is integrated, which below a predetermined pressure or when no fluid communication is provided between the dialyzer and the line shuts off the flow cross-section of the flow channel.

Abstract: Blood treatment/dialysis systems are disclosed. The systems include a water treatment unit, preferably of the reverse osmosis type, whose outlet has connected thereto a water supply line provided with a number of branch connections having fluidly coupled thereto blood treatment/dialysis machines in a selective manner, and a drain line through which exhausted blood treatment fluid can be discharged from fluidly coupled blood treatment/dialysis machines. Also disclosed is a machine-external heat exchanger, which is connected to the water supply line upstream of the branch connections on one side and to the drain line on the other side.

Abstract: A system for acquiring or measuring information relating to a state of dialysance, identifying a dialyzer apparatus, or identifying a membrane filter device during the operation of the dialyzer apparatus in a dialysis treatment of a patient. The dialyzer apparatus includes a housing having an internal volume portion and a membrane filter device arranged within the internal volume portion. The housing allows transmission of radiation. A sensor device connected to the housing of the dialyzer apparatus includes a signal receiving device designed to receive a radiation signal, from the housing, the signal characteristic of the state or the identification of the dialyzer apparatus or of the membrane filter unit of the dialyzer apparatus.

Abstract: A device for integrating a monitor in a case comprises a support element made from plastic material and having a recess which corresponds to a predetermined visible area of the monitor. The support element includes a plurality of apertures which are arranged at a predetermined distribution outside the recess for passing through positioning and/or retaining elements and placing the support element at a predetermined position on a sheet-metal case in which the support element can be received, and a frame section which projects from a base area of the support element on a rear side thereof and is arranged in sandwich design for receiving components of the monitor. The components of the monitor received in the frame section are adapted to be fixed to the support element, and the support element is adapted to be fixed to the at least one of positioning or retaining elements on the sheet-metal case.

Abstract: The invention relates to an extracorporeal blood treatment machine, such as a dialysis machine, comprising leakage detection as well as to a method of detecting leakages in the dialysis fluid circuit of a dialysis machine, wherein at least part of the dialysis fluid system to be monitored in terms of leakage is accommodated in a hermetically sealed housing and the housing is or can be ventilated in a controlled manner, and wherein a parameter, such as the air humidity of the air flowing into the housing is compared to a corresponding parameter, preferably air humidity of the air flowing out of the housing.