Abstract: Connector systems for a fluid container for pharmaceutical solutions are disclosed. The systems include an outer part adapted for insertion into a fluid conducting system and an inner part arranged in said outer part. The outer part includes a tamper-evident closure connected thereto at a predetermined breaking point that can be manually removed. An external side of the inner part abuts an internal side of the outer part. A closure element attached to the inner part prevents a flow of fluid through the inner part. The inner part and the outer part having provided thereon at least one fluid conducting element, such as a furrow, a flute, a depression or a groove. Medical supply systems comprising a bag, such as a dialysis bag, having such systems are also described.

Abstract: A recirculation device of an extracorporeal blood treatment device is disclosed with a preferably universal medical fluid container to which an arterial line section of a fluid conducting system of the extracorporeal blood treatment device can be connected as an option. Furthermore, the recirculation device has a 3-way switch, preferably a 3-way valve, which is arranged directly downstream of the universal medical fluid container. A conduit of the 3-way switch is preferably coupled with a spike or a similar connecting device or is formed in one piece together with it.

Abstract: An apparatus for performing blood therapy having a plurality of pumps for engaging blood and fluid tubing is characterized by a plurality of manually mounted and disengagable panels installed on the sides of the apparatus housing, the panels having pump engaging tubing mounted on the inside of the respective panels.

Abstract: A method and a device for determining a recirculation during a dialysis on the basis of the response of the dialysis system to an alteration of a system-related operating value are described. Recirculation may be determined by establishing, at the side of the dialysis liquid, a reference parameter that represents the concentration of uremic toxins from the extracorporeal circulation, and calculating a target parameter for a system-related target operational value from the reference parameter, presetting the system-related target operational value and establishing an actual parameter related to the system-related target operational value, determining an actual comparative value from the actual parameter and the reference parameter related to the system-related target operational value and comparing the actual comparative value with a system-specific target comparative value related to the system-related target operational value, and converting the comparison result into a recirculation degree.

Abstract: Disclosed is a filling device of a fluid conducting system of an extracorporeal blood treatment device that includes a spike for connecting to the single fluid connector of a medical fluid container and a manually operable fluid blocking mechanism arranged directly downstream of the spike that fluidly connects with the spike while the filling device is in operation. The fluid blocking mechanism has at least one fluid outlet connector that is adapted so that a line section or hose of the fluid conducting system such as the arterial line section of a blood purification device can be connected to it in a detachable manner while the filling device is in operation.

Abstract: Tube roller pumps for blood treatment devices are disclosed. The pumps include a curved surface with a rotor rotatable therein. The rotor attaches via a shaft reception to a drive shaft of the pump. The rotor has a first locking element for axially locking the rotor on the shaft and a second locking element for rotationally coupling the shaft and the rotor. The shaft reception and the drive shaft guide the rotor to a position on the shaft, when pushed onto the shaft, and, at this position, the first element may be moved by the shaft from locked to released. The rotor, when pushed further onto the shaft, is moved to another position at which the first element is automatically moved back to locked and the second element may be brought into manual engagement with the shaft to transmit torque from the shaft to the rotor.

Abstract: Disclosed is a filling and recirculation device of a fluid conducting system for blood treatment which has a fluid connector and a three-dimensional four-way valve with a first valve plane on which an inlet connector for the fluid container, an arterial line connector, and a valve-internal coupling connector are arranged and a second valve plane on which an outlet connector and a venous line connector are arranged. The venous line connector is permanently connected with the valve-internal coupling connector. A manually operable valve rotary piston of the four-way valve has a first control section assigned to the first valve plane and a second control section assigned to the second valve plane.

Abstract: The described system and method for blood treatment are configured to detect at least two hemodynamic parameters, for example the blood pressure and the relative blood volume, during the blood treatment. At least two fuzzy modules receive measuring values of the hemodynamic parameters as input variables, wherein the output signals transmitted by the fuzzy modules are weighted by at least one weighting module. A setting means effectuates setting of at least one variable, for example an ultrafiltration rate, a dialysis fluid conductivity or a dialysis fluid temperature, in response to the output signal transmitted by the weighting module. In this way, e.g. threatening intradialytic hypotensive episodes can be detected and avoided. The system can be designed as a dialyzer for hemodialysis, hemofiltration or hemodiafiltration.

Abstract: Disclosed is an anti-contamination device for preventing contamination of a fluid stored in a fluid container with a spike and a manually operable fluid blocking mechanism arranged directly downstream of the spike. A non-return valve is arranged between the spike and the fluid blocking mechanism, and that valve is adapted to allow only a flow from the spike in the direction of the manually operable fluid blocking mechanism.

Abstract: Systems and methods are disclosed for detecting an interruption of connection between a blood treatment apparatus and a patient blood circulation. The system includes a line shut-off for blocking the venous fluid line arranged between the blood treatment apparatus and a connector, an arterial fluid line arranged between the blood treatment apparatus and the patient blood circulation, a pressure sensor arranged in the venous fluid line or the arterial fluid line for measuring pressure, and a control and evaluation unit for evaluating a pressure curve in time of the pressure measured by the pressure sensor during blocking of the venous fluid line to detect an interruption or disturbance of the connection between the first connection means and the patient blood circulation.

Abstract: A machine for extracorporeal blood treatment comprising a machine-side fluid circuit is disclosed. The machine comprises a heat exchanger for heating cold purification fluid freshly supplied on its intake side, for which purpose used still warm purification fluid flows past its opposite discharge side for a heat exchange, and a circulation valve for changing over between a blood purification mode in which the used purification fluid is disposed of in an open fluid circuit through the discharge side of the heat exchanger into a drain and a disinfection mode in which hot disinfectant is circulated in a closed circuit. The circulation valve is connected downstream of the heat exchanger with respect to the discharge side thereof.

Abstract: Methods and apparatus are disclosed for determining a substance in a fluid excreted/extracted from the body or spent dialysate, e.g., for determining a quality measure for the dialysis, such as the concentration of selected toxic substances, and/or for determining a removed total quantity of uremic toxins during a dialysis with a dialysis apparatus. A concentration of a substance in the fluid may be determined by: detecting, by an absorption sensor, a first extinction signal of the fluid at an analysis wavelength at a defined first pH value of the fluid; adjusting, by a pH adjusting device, a second pH value of the fluid which differs from the first pH value; detecting, by the absorption sensor, a second extinction signal of the fluid at the analysis wavelength at the second pH value; and processing/comparing the two extinction signals for the first and the second pH values and determining an absolute concentration of the substance dissolved in the fluid.

Abstract: A lid apparatus for a medical device for extracorporeal blood treatment that includes a lid which is hinged by means of at least one pivot joint at the medical device is disclosed. The pivot joint includes thereby a first joint section which may be positioned at the lid, and a second joint section which may be connectable to the medical device, wherein the joint sections are pivotable about a pivot axis at least between a first position, in which the lid is open, and a second position, in which the lid covers at least a part of the medical device, wherein also the joint sections are latchable in at least one pivoting position.

Abstract: Holding devices for a medical device including a holder and a second component part by which the holder is coupled or adapted to be coupled are disclosed. The holder has a receiving portion into which a functional member can be detachably introduced. The holder further includes a pivot portion about which the holder is pivoted about an axis of rotation to a support of the second component part, wherein the support is movable vis-à-vis the second component part in a spring-loaded manner. The second component part includes a recess within which the pivot portion and the support are arranged so that upon pivoting the holder about the axis of rotation merely the receiving portion protrudes from the recess. Medical devices for extracorporeal blood treatment including a holding device of this type are also disclosed.

Abstract: The present invention relates to a method and a device for the measurement of pressure signals in a blood treatment system, whereby system changes can be identified and can be differentiated additionally reliably between system changes in blood flow direction and in transmembrane direction in order to enable a targeted action.

Abstract: Medical devices for extracorporeal blood treatment including tube roller pumps. Tube roller pumps including a pump housing having a bent bearing surface and a rotor being rotatable inside the bearing surface, wherein a tubing segment can be introduced between the bearing surface and the rotor in the form of a loop. A stationary first receiving portion for accommodating one end of the loop-shaped tubing segment and a rocker arm including a second receiving portion for accommodating the other end of the loop-shaped tubing segment is located at the pump housing, wherein the rocker arm is rotatable about a pivoting axis so that the second receiving portion with the tubing segment can be brought into at least two different positions and that a first position represents a threading position and a second position represents an unthreading position for the tubing segment.

Abstract: Methods and devices implementing, for detecting a recirculation, at the side of a dialysis solution, by a blood-sided administration of a bolus are disclosed. Recirculation may be detected by: measuring a first light absorbance value (ad) of a dialysis solution (d) draining off a dialyzer using a spectrometer, prior to the administration of the bolus; venous administration of the bolus having a predefined volume (QBven) at the venous access; measuring a second light absorbance value (bd) of the draining dialysis solution using a spectrometer, after the administration of the bolus; and determining a change in the absorbance value between the first (ad) and second (bd) measured absorbance values due to the presence of a bolus in the dialysis solution during recirculation as a basis for the recirculation quantification.