Abstract: The present invention covers aminothiazole compounds of general formula (I), in which R1, R2, R3 and R4 are as defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds and the use of said compounds for manufacturing pharmaceutical compositions for the treatment and/or prophylaxis of diseases, in particular of diacylglycerol kinase zeta (DGK?) regulated disorders, as a sole agent or in combination with other active ingredients.

Abstract: The present invention relates to novel Mannose-binding lectin (MBL)-associated serine protease (MASP) inhibitory compounds, as well as analogues and derivatives thereof, to processes for the preparation thereof, to the use thereof alone or in combinations for treatment and/or prevention of diseases and to the use thereof for production of medicaments for treatment and/or prevention of diseases, especially for treatment and/or prevention of renal and cardiovascular disorders and of ischemia reperfusion injuries.

Abstract: The invention relates to a method and a system for pesticide management of an arable field, in particular taking into account health-related data of pollinators. The invention also relates to a computer program product and to a storage medium.

Abstract: The present invention relates to pharmaceutical compositions and combinations comprising regorafenib or its hydrate, solvate, metabolite or pharmaceutically acceptable salt or a polymorph thereof and a PD-1/PD-L1(2) inhibitor for treating, preventing or managing diseases and conditions including hyperproliferative disorders such as cancer in humans and other mammals.

Abstract: The present disclosure relates to substituted thiophene carboxamides and analogues thereof of formula (I) that may be used for protecting plants from bacterial diseases, in particular from bacterial diseases caused by bacteria belonging to the genus Xanthomonas.

Abstract: The present invention includes compounds of formula (I) and methods for its preparation and treatment of disorders with activated peroxisome preoliferator-activated receptor gamma (PPARG), particularly cancer.

Abstract: The present disclosure relates to a liquid pharmaceutical formulation comprising a DOSA-derived tetra-chelate of formula (I), in which M is an ion of a paramagnetic metal, preferably a Gd3+ ion, and R1, R2, R3, R4 and R5 are as defined in the claims, in a pharmaceutical acceptable solvent. The present disclosure also relates to a method of preparation of said liquid pharmaceutical formulation and to a method of imaging involving said liquid pharmaceutical formulation.

Abstract: The invention relates to a system, a method and the use of the system according to the invention for controlling undesirable plants, in particular on railway tracks, using electrical energy.

Abstract: The invention relates to the monitoring of products by means of active radio tags. According to the invention, packagings of products are provided with an active radio tag that detects at least one environmental condition and/or at least one packaging state, and which emits a signal at time intervals, which provides information about a unique identifier and at least one state in which the respective product is found. The signal is picked up by a receiver that extracts the unique identifier and the state information and transmits same together with location information to an external server.

Abstract: The invention relates to the monitoring of products by means of active radio tags. According to the invention, packagings of products are provided with an active radio tag that detects at least one environmental condition and/or at least one packaging state, and which emits a signal at time intervals, which provides information about a unique identifier and at least one state in which the respective product is found. The signal is picked up by a receiver that extracts the unique identifier and the state information and transmits same together with location information to an external server.

Abstract: The invention relates to the monitoring of products by means of active radio tags. According to the invention, packagings of products are provided with an active radio tag that detects at least one environmental condition and/or at least one packaging state, and which emits a signal at time intervals, which provides information about a unique identifier and at least one state in which the respective product is found. The signal is picked up by a receiver that extracts the unique identifier and the state information and transmits same together with location information to an external server.

Abstract: The invention relates to the monitoring of products by means of active radio tags. According to the invention, packagings of products are provided with an active radio tag that detects at least one environmental condition and/or at least one packaging state, and which emits a signal at time intervals, which provides information about a unique identifier and at least one state in which the respective product is found. The signal is picked up by a receiver that extracts the unique identifier and the state information and transmits same together with location information to an external server.

Abstract: The invention relates to novel compounds of the formula (I) in which X, R1, R2, R3, V and n have the meanings given above, to the use thereof as acaricides and/or insecticides for controlling animal pests and to methods and intermediates for the preparation thereof.

Abstract: The present disclosure is concerned with the technical field of marking objects with optically readable codes and reading out (decoding) the codes. Subjects of the present disclosure are a method, a system and a computer program product for decoding optically readable codes introduced in surfaces of objects.

Abstract: Systems, methods, and computer programs disclosed herein relate to training a machine learning model to generate multimodal representations of objects, and to the use of said representations for predictive purposes.

Abstract: The invention relates to a method for transferring a pourable medium (10) from a first vessel (12) into a second vessel (14), by means of a robot arm (16), wherein a movement 118) of the robot arm (16) can be controlled by at least one movement parameter (BP), including, inter alia, the following method steps: d) determining the mass of the medium (10) transferred into the second vessel (14) as an actual filling mass (IFM), and also the variation over time of the actual filling mass (IFM) of the medium (30; as an actual mass flow (IMS), by means of a balance 124), c) calculating a correcting mass flow (StMS) as a correcting variable (26) of a first control circuit (28) while taking into account the actual filling mass (FM) and the intended filling mass (SFM), f) using the correcting variable (26) of die first control circuit (28) as a reference variable (30) of a second control circuit (32) for the purpose that the calculated correcting mass flow (StMS) is used as the intended mass flow (SMS), g) calculating

Abstract: A system, method, and computer program product for predicting, anticipating, and/or assessing tissue characteristics obtains measurement information associated with a parameter of a voxel of tissue of a patient measured at two or more time points, the two or more time points occurring before one or more characteristics of the voxel of the tissue are separable in an image generated based on the parameter of the voxel measured at a single time point of the two or more time points, and determines, based on the parameter of the voxel at the two or more time points, the one or more characteristics of the voxel of the tissue.

Abstract: The invention relates to substituted S-alaninate derivatives and to processes for their preparation, and also to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular vascular disorders, preferably thrombotic or thromboembolic disorders and/or thrombotic or thromboembolic complications.

Abstract: The present invention relates to the technical field of producing artificial contrast-enhanced radiological images by way of machine learning methods.

Abstract: A method for providing a prediction of a representation of an examination region that was generated using a medical image technique involving a contrast agent may include receiving a first representation in frequency space of an examination region of an examination object, receiving a second representation in the frequency space of the examination region of the examination object, providing the first representation and the second representation as an input to a predictive machine learning model that is configured to provide, as an output, a prediction of a representation in the frequency space of the examination region with an amount of the contrast agent administered during a medical imaging technique, receiving the output of the predictive machine learning model based on the input, and converting the output of the predictive machine learning model to a representation in real space of the examination region of the examination object.