Patents Assigned to Bayer Aktiengesellschaft
  • Patent number: 11911913
    Abstract: The invention relates to a method for transferring a pourable medium (10) from a first vessel (12) into a second vessel (14), by means of a robot arm (16), wherein a movement 118) of the robot arm (16) can be controlled by at least one movement parameter (BP), including, inter alia, the following method steps: d) determining the mass of the medium (10) transferred into the second vessel (14) as an actual filling mass (IFM), and also the variation over time of the actual filling mass (IFM) of the medium (30; as an actual mass flow (IMS), by means of a balance 124), c) calculating a correcting mass flow (StMS) as a correcting variable (26) of a first control circuit (28) while taking into account the actual filling mass (FM) and the intended filling mass (SFM), f) using the correcting variable (26) of die first control circuit (28) as a reference variable (30) of a second control circuit (32) for the purpose that the calculated correcting mass flow (StMS) is used as the intended mass flow (SMS), g) calculating
    Type: Grant
    Filed: November 21, 2019
    Date of Patent: February 27, 2024
    Assignee: BAYER AKTIENGESELLSCHAFT
    Inventors: Leslaw Mleczko, Armin Schweiger, Kathrin Wegener, Carl-Helmut Coulon
  • Patent number: 11912692
    Abstract: The invention relates to substituted S-alaninate derivatives and to processes for their preparation, and also to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular vascular disorders, preferably thrombotic or thromboembolic disorders and/or thrombotic or thromboembolic complications.
    Type: Grant
    Filed: August 11, 2023
    Date of Patent: February 27, 2024
    Assignee: Bayer Aktiengesellschaft
    Inventors: Hartmut Beck, Stefanie Mesch, Alexandros Vakalopoulos, Nils Pfaff, Stefanie Zimmermann, Markus Follmann, Elisabeth Kersten, Guillaume Levilain, Kartrin Partikel, Andreas Peter Broehl, Stefan Heitmeier, Julia Dietze-Torres, Lutz Lehmann, Kersten Matthias Gericke, Frank Süßmeier, Lars Bärfacker, Alexander Hillisch, Adrian Tersteegen, Anja Buchmüller, Christoph Gerdes
  • Patent number: 11915361
    Abstract: A system, method, and computer program product for predicting, anticipating, and/or assessing tissue characteristics obtains measurement information associated with a parameter of a voxel of tissue of a patient measured at two or more time points, the two or more time points occurring before one or more characteristics of the voxel of the tissue are separable in an image generated based on the parameter of the voxel measured at a single time point of the two or more time points, and determines, based on the parameter of the voxel at the two or more time points, the one or more characteristics of the voxel of the tissue.
    Type: Grant
    Filed: September 17, 2020
    Date of Patent: February 27, 2024
    Assignee: BAYER AKTIENGESELLSCHAFT
    Inventors: Martin Rohrer, Gesine Knobloch, Arthur Uber, III
  • Publication number: 20240050053
    Abstract: The present invention relates to the technical field of producing artificial contrast-enhanced radiological images by way of machine learning methods.
    Type: Application
    Filed: November 29, 2021
    Publication date: February 15, 2024
    Applicant: Bayer Aktiengesellschaft
    Inventors: Matthias LENGA, Marvin PURTORAB
  • Publication number: 20240050054
    Abstract: A method for providing a prediction of a representation of an examination region that was generated using a medical image technique involving a contrast agent may include receiving a first representation in frequency space of an examination region of an examination object, receiving a second representation in the frequency space of the examination region of the examination object, providing the first representation and the second representation as an input to a predictive machine learning model that is configured to provide, as an output, a prediction of a representation in the frequency space of the examination region with an amount of the contrast agent administered during a medical imaging technique, receiving the output of the predictive machine learning model based on the input, and converting the output of the predictive machine learning model to a representation in real space of the examination region of the examination object.
    Type: Application
    Filed: November 29, 2021
    Publication date: February 15, 2024
    Applicant: Bayer Aktiengesellschaft
    Inventors: Matthias LENGA, Marvin PURTORAB
  • Patent number: 11897904
    Abstract: Benzoylamides of the general formula (I) are described as herbicides. In this formula (I), B, X1 and X2 represent N, O or S(O)n. R, Ra, Rb and Rx represent radicals such as hydrogen, halogen, (C1-C6)-alkyl, halo-(C1-C6)-alkyl, (C1-C6)-alkyloxy and cyano.
    Type: Grant
    Filed: November 15, 2018
    Date of Patent: February 13, 2024
    Assignee: Bayer Aktiengesellschaft
    Inventors: Frank Memmel, Ralf Braun, Christian Waldraff, Gunter Karig, Simon Doerner-Rieping, Isolde Haeuser-Hahn, Anu Bheemaiah Machettira, Hansjoerg Dietrich, Elmar Gatzweiler, Christopher Hugh Rosinger
  • Patent number: 11897867
    Abstract: The present invention provides 6-phenyl-4,5-dihydropyridazin-3(2H)-one derivatives of formula (I): The present invention provides 6-phenyl-4,5-dihydropyridazin-3(2H)-one derivatives of formula (I):
    Type: Grant
    Filed: August 2, 2018
    Date of Patent: February 13, 2024
    Assignees: Bayer Aktiengesellschaft, Bayer Pharma Aktiengesellschaft, The Broad Institute, Inc.
    Inventors: Manuel Ellermann, Timothy Lewis
  • Patent number: 11891404
    Abstract: The present invention relates to substituted macrocyclic indole derivatives of general formula (I): in which R1, R2, R3, R4, R5, R6, A and L are as defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds, and the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular of hyperproliferative disorders, as a sole agent or in combination with other active ingredients.
    Type: Grant
    Filed: September 8, 2022
    Date of Patent: February 6, 2024
    Assignees: Bayer Aktiengesellschaft, Bayer Pharma Aktiengesellschaft, The Broad Institute, Inc.
    Inventors: Kai Thede, Anne Mengel, Clara Christ, Joachim Kuhnke, Sarah Anna Liesa Johannes, Philipp Buchgraber, Ulrich Klar, Ulrike Rauh, Stefan Kaulfuss, Amaury Ernesto Fernandez-Montalvan, Nicolas Werbeck, Ursula Moenning, Katrin Nowak-Reppel, Sven Wittrock, David McKinney, Michael H. Serrano-Wu, Chris Lemke, Mark Fitzgerald, Christopher Nasveschuk, Kiel Lazarski, Steven James Ferrara, Laura Furst, Guo Wei, Patrick Ryan McCarren, Rebecca Ann Harvey
  • Patent number: 11884643
    Abstract: The present disclosure relates to thienyloxazolones and analogues thereof of formula (III) that may be used for protecting plants from bacterial diseases, in particular from bacterial diseases caused by bacteria belonging to the genus Xanthomonas.
    Type: Grant
    Filed: July 3, 2019
    Date of Patent: January 30, 2024
    Assignee: Bayer Aktiengesellschaft
    Inventors: David Bernier, Stéphane Brunet, Jérémy Dufour, Thomas Knobloch, Lionel Nicolas, Tomoki Tsuchiya
  • Publication number: 20240016152
    Abstract: The present invention relates to active compound combinations, in particular within a fungicide composition, which comprise as compound (A) a compound of formula (I) and as compound (B) a further fungicidally active compound as specified below. Moreover, the invention relates to compositions comprising such compound combination and to the use of the compound combinations and the fungicide compositions as biologically active agent, especially for control of phytopathogenic fungi in crop protection and in the protection of industrial materials and as plant growth regulators.
    Type: Application
    Filed: June 16, 2021
    Publication date: January 18, 2024
    Applicant: Bayer Aktiengesellschaft
    Inventors: Agostinos Michael KLÜKEN, Julie GEIST, Cyril MONTAGNE, Anthony MILLET, Lionel NICOLAS, Tomoki TSUCHIYA
  • Patent number: 11864557
    Abstract: The present invention relates to novel heteroaryl-triazole and heteroaryl-tetrazole compounds of the general formula (I), in which the structural elements Y, Q1, Q2, R1, R2, R3, R4 and R5 have the meaning given in the description, to formulations and compositions comprising such compounds and for their use in the control of animal pests including arthropods and insects in plant protection and to their use for control of ectoparasites on animals.
    Type: Grant
    Filed: September 29, 2022
    Date of Patent: January 9, 2024
    Assignee: BAYER AKTIENGESELLSCHAFT
    Inventors: Alexander Arlt, Werner Hallenbach, Hans-Georg Schwarz, Martin Fuesslein, Heinz-Juergen Wroblowsky, Estella Buscato Arsequell, Marc Linka, Kerstin Ilg, Arunas Jonas Damijonaitis, Ulrich Ebbinghaus-Kintscher, Ulrich Goergens, Yolanda Cancho Grande, Peter Jeschke, Joachim Telser, Iring Heisler, Andreas Turberg
  • Publication number: 20240005650
    Abstract: Systems, methods, and computer programs disclosed herein relate to training of machine learning models on the basis of image training data with a limited number of labeled images.
    Type: Application
    Filed: November 12, 2021
    Publication date: January 4, 2024
    Applicant: Bayer Aktiengesellschaft
    Inventors: Jonas DIPPEL, Steffen VOGLER, Johannes HÖHNE
  • Publication number: 20240000767
    Abstract: The present invention relates to a combination of selective blockers of TASK-1 and TASK-3 channels, in particular substituted imidazo [1,2-a]pyrimidine and substituted imidazo [1,2-a]pyridine derivatives of formula (II) and ?2-Adrenoceptor subtype C (alpha-2C) antagonists, in particular substituted heterocyclic carboxamides of formula (I) for the treatment and/or prophylaxis of sleep-related breathing disorders, preferably obstructive and central sleep apneas and snoring.
    Type: Application
    Filed: July 5, 2021
    Publication date: January 4, 2024
    Applicant: Bayer Aktiengesellschaft
    Inventors: Martina DELBECK, Michael HAHN
  • Publication number: 20230416249
    Abstract: Compounds of formula (I) processes for their production and their use as pharmaceuticals.
    Type: Application
    Filed: May 10, 2023
    Publication date: December 28, 2023
    Applicants: Bayer Aktiengesellschaft, Bayer Pharma Aktiengesellschaft, The Broad Institute, Inc., Dana-Farber Cancer Institute, Inc.
    Inventors: Stephan SIEGEL, Franziska SIEGEL, Volker SCHULZE, Markus BERGER, Keith GRAHAM, Ulrich KLAR, Jeremie Xavier G. MORTIER, Detlev SÜLZLE, Ulf BÖMER, Daniel KORR, Jens SCHRÖDER, Matthew MEYERSON, Heidi GREULICH, Bethany KAPLAN
  • Publication number: 20230405015
    Abstract: The present invention provides a method of treatment of sarcoma comprising administering to a patient in need thereof a compound of general formula (I), in which R1, R2, R3, and R4, are as defined herein, alone or in pharmaceutical compositions or combinations comprising said compounds as a sole agent or in combination with other active ingredients.
    Type: Application
    Filed: August 31, 2023
    Publication date: December 21, 2023
    Applicants: Bayer Aktiengesellschaft, The Broad Institute, Inc., Dana-Farber Cancer Institute, Inc.
    Inventors: Martin LANGE, Stefan KAULFUSS, Charlotte Christine KOPITZ, Heidi GREULICH, Xiaoyun WU, Matthew MEYERSON
  • Patent number: 11834434
    Abstract: Substituted 2-heteroaryloxypyridines and salts thereof and use thereof as herbicidal active substances Substituted 2-heteroaryloxypyridines of the general formula (I) are described, and their use as herbicides, in particular for controlling broad-leaved weeds and/or weed grasses in crops of useful plants and/or as plant growth regulators for influencing the growth of crops of useful plants. The present invention further relates to herbicidal and/or plant growth-regulating compositions comprising one or more compounds of the general formula (I).
    Type: Grant
    Filed: June 19, 2019
    Date of Patent: December 5, 2023
    Assignee: Bayer Aktiengesellschaft
    Inventors: Michael Charles McLeod, Ralf Braun, Anu Bheemaiah Machettira, Dirk Schmutzler, Elisabeth Asmus, Christopher Hugh Rosinger, Elmar Gatzweiler
  • Patent number: 11819025
    Abstract: The present invention relates to novel active compound combinations comprising at least one known compound of the formula (I) and at least one further active compound, which combinations are highly suitable for controlling animal and microbial pests such as unwanted insects and/or unwanted acarids and/or unwanted nematodes.
    Type: Grant
    Filed: October 12, 2018
    Date of Patent: November 21, 2023
    Assignee: Bayer Aktiengesellschaft
    Inventors: Silvia Cerezo-Galvez, Christian Marienhagen, Holger Weckwert, Wolfgang Thielert, Marita John
  • Patent number: 11820687
    Abstract: Systems and methods for treating liquid effluent, the effluent including contaminants capable of biodegradation, using biodegradation beds. While the effluent holding tank is housed within a containment facility in the event of holding tank rupture or leakage, the biodegradation beds and an excess effluent sump are housed adjacent but outside the containment facility. In some aspects, the biodegradation beds are covered with generally transparent covers to allow sunlight to heat the bed contents and effluent for degradation and evaporation purposes while avoiding introduction of unwanted ambient precipitation.
    Type: Grant
    Filed: April 26, 2019
    Date of Patent: November 21, 2023
    Assignee: Bayer Aktiengesellschaft
    Inventor: Dale Andrew Watchman
  • Publication number: 20230365524
    Abstract: The present invention provides triazolone compounds of general formula (I): in which R1, R2, R3, R4, and R5 are as defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds and the use of said compounds for manufacturing pharmaceutical compositions for the treatment and prophylaxis of diseases, in particular hyperproliferative disorders, as a sole agent or in combination with other active ingredients.
    Type: Application
    Filed: April 20, 2023
    Publication date: November 16, 2023
    Applicants: Bayer Aktiengesellschaft, Bayer Pharma Aktiengesellschaft, The Broad Institute, Inc., President and Fellows of Harvard College, The General Hospital Corporation
    Inventors: Stefan Nikolaus GRADL, Duy NGUYEN, Knut EIS, Judith GÜNTHER, Timo STELLFELD, Andreas JANZER, Sven CHRISTIAN, Thomas MÜLLER, Sherif El SHEIKH, Han Jie ZHOU, Changjia ZHAO, David B. SYKES, Steven James FERRARA, Kery LIU, Michael KRÖBER, Claudia MERZ, Michael NIEHUES, Martina SCHÄFER, Katja ZIMMERMANN, Carl Friedrich NISING
  • Publication number: 20230354812
    Abstract: The present invention relates to oxadiazinylpyridazine compounds and the uses thereof for controlling phytopathogenic microorganisms such as phytopathogenic fungi. It also relates to processes and intermediates for preparing these compounds.
    Type: Application
    Filed: June 16, 2021
    Publication date: November 9, 2023
    Applicant: Bayer Aktiengesellschaft
    Inventors: Julie GEIST, Cyril MONTAGNE, Lionel NICOLAS, Tomoki TSUCHIYA, Vincent THOMAS, Dominique LOQUE