Abstract: A method and apparatus for determining the position of each eye of a human operator (12) with respect to a fixed reference point or with respect to each other by using electro-oculogram signals produced by eye movement. Human operator (12) wears sensor assembly (10) which includes a plurality of sensors (14) which are arranged to monitor right and left, as well as horizontal and vertical eye movement. The sensed electro-oculogram signals are processed by a microprocessor (60) into separate positional signals representing upward movement, downward movement, movement to the left, movement to the right, convergence, and divergence. These positional signals are used to control three dimensional imagery on a computer, video game, or other apparatus to be controlled, or for strabismus measurement and diagnosis.

Abstract: A method and apparatus for determining the position of each eye of a human operator (12) with respect to a fixed reference point or with respect to each other by using electro-oculogram signals produced by eye movement. Human operator (12) wears sensor assembly (10) which includes a plurality of sensors (14) which are arranged to monitor right and left, as well as horizontal and vertical eye movement. The sensed electro-oculogram signals are processed by a microprocessor (60) into separate positional signals representing upward movement, downward movement, movement to the left, movement to the right, convergence, and divergence. These positional signals are used to control three dimensional imagery on a computer, video game, or other apparatus to be controlled, or for strabismus measurement and diagnosis.

Abstract: There is disclosed an improved method for testing for the presence of a particular microorganism or group of microorganisms characterized by a particular enzyme. The method uses a dye-forming substrate throughout a polymer matrix or on the surface of a solid support member that forms a colored precipitate when cleaved by the enzyme. The precipitate is concentrated to the polymer matrix and/or solid support member to create a visible reaction product, wherein the amount of dye-forming substrate needed is independent of the sample size. The present invention further comprises an enzyme indicator device comprising a dye-forming substrate throughout a polymer system or on the surface of a solid support member.

Abstract: There is disclosed a process and a device for detecting and measuring (1) the amount of enzyme present as a detecting system following a nucleic acid hybridization reaction or immunoreaction; (2) the level and activity of free enzyme in a biological sample; (3) the level of enzyme from contaminating microorganisms present in a sample; and (4) enzymes from pure culture isolates for microbial identification and antimicrobial susceptibility testing.

Abstract: A method and apparatus for determining the position of each eye of a human operator (12) with respect to a fixed reference point or with respect to each other by using electro-oculogram signals produced by eye movement. Human operator (12) wears sensor assembly (10) which includes a plurality of sensors (14) which are arranged to monitor right and left, as well as horizontal and vertical eye movement. The sensed electro-oculogram signals are processed by a microprocessor (60) into separate positional signals representing upward movement, downward movement, movement to the left, movement to the right, convergence, and divergence. These positional signals are used to control three dimensional imagery on a computer, video game, or other apparatus to be controlled, or for strabismus measurement and diagnosis.

Abstract: There is disclosed a process and a device for detecting and measuring (1) the amount of enzyme present as a detecting system following a nucleic acid hybridization reaction or immunoreaction; (2) the level and activity of free enzyme in a biological sample; (3) the level of enzyme from contaminating microorganisms present in a sample; and (4) enzymes from pure culture isolates for microbial identification and antimicrobial susceptibility testing.

Abstract: A device for detecting the presence of a particular motile organism within a sample are disclosed. The sample may be derived from dry milk, raw meat, poultry or a clinical specimen. A preferred method of using the device includes inoculating a selective enrichment medium containing a chemotactic attractant with the sample and contacting the selective enrichment medium with a nonselective motility medium containing a chemotactic attractant in a concentration less than the attractant concentration in the selective enrichment medium. Upon incubation, the motile organism metabolizes the chemotactic attractant, allowing the organism to move into the motility medium where it interacts with antibodies specific for the organism, thereby causing the formation of a persistent immobilization band. The device is particularly useful in detecting Salmonella.This application is a divisional of U.S. Ser. No. 773,201, filed Sep. 9, 1985 and issued as U.S. Pat. NO. 4,920,063 on Apr.

Abstract: There is disclosed an apparatus, a device, and a method using the inventive device and apparatus for the sequential enrichment of a particular microorganism to a threshold level to allow for its detection. The use of the apparatus for sequential microbial enrichment shortens the time period normally spent to enrich samples to permit the growth of enough microorganisms to detect the particular microorganism(s) of interest. The invention eliminates the need for multiple manual transfers of potentially biohazardous materials.

Abstract: Methods and associated devices for detecting the presence of a particular motile organism within a sample are disclosed. The sample may be derived from dry milk, raw meat, poultry or a clinical specimen. A preferred method includes inoculating a selective enrichment medium containing a chemotactic attractant with the sample and contacting the selective enrichment medium with a nonselective motility medium containing a chemotatic attractant in a concentration less than the attractant concentration in the selective enrichment medium. Upon incubation, the motile organism metabolizes the chemotactic attractant, allowing the organism to move into the motility medium where it interacts with antibodies specific for the organism, thereby causing the formation of a persistent immobilization band. The methods are particularly useful in detecting Salmonella.

Abstract: A device is adapted for containing a volume of growth medium and employed for detection of gas produced by a microorganism or microorganisms putatively contained within a test sample and added to the growth medium, comprising a primary chamber, a dome defined by the top surface of the primary chamber and communicating therewith, the dome establishing a fluid level and adapted for collection of gas produced by a microorganism within the growth medium, and a fill section adjacent to and communicating with one end of the primary chamber, the fill section spaced apart from the dome and extending above the fluid level, and further defining an opening for the addition of a test sample. The device may be sealed by means of a removable closure. An apparatus also consists of an array of substantially identical devices is also disclosed.