Patents Assigned to Biotronik AG
  • Balloon catheter, in particular for delivering drugs or stents in the region of a stenosis
    Patent number: 9770575
    Abstract: A balloon catheter, in particular for delivering medicaments, stents or medicament-coated stents in the region of a stenosis, comprising an outer shaft (4) an inner shaft (6), and a balloon (7) at the distal catheter end, which balloon is dilatable by a feedable pressure fluid and which is attached with its proximal end (8) to the outer shaft (4) and with its distal end (9) to the inner shaft (6) which protrudes the outer shaft (4) in the distal direction, and a cover sheath (15) which is seated in a covering position over the contracted balloon (7) and is displaceably guided on the outer shaft (4) and which is displaceable on the outer shaft (4) in the proximal direction via its front opening (17) by the dilating balloon (7) while continuously releasing the same from distal to proximal.
    Type: Grant
    Filed: October 27, 2011
    Date of Patent: September 26, 2017
    Assignee: Biotronik AG
    Inventors: Matthias Wesselmann, Tobias Brunner, Hans Lang
  • Medical device for evaluating a temperature signal
    Patent number: 9770292
    Abstract: A medical device including an evaluation unit and an electrode line. The electrode line includes at least one temperature sensor. The temperature sensor delivers a temperature signal to the evaluation unit. The evaluation unit evaluates periodic fluctuations of a signal level of the temperature signal and generates an evaluation output signal qualifying constant wall touching of the electrode line according to whether periodic fluctuations of a signal level of the temperature signal lie below or above a predetermined limit value.
    Type: Grant
    Filed: September 10, 2014
    Date of Patent: September 26, 2017
    Assignee: BIOTRONIK AG
    Inventor: Christian Moss
  • Cobalt alloy for medical implants and stent comprising the alloy
    Patent number: 9757224
    Abstract: An embodiment of the invention relates to a cobalt-based alloy, which due to the composition exhibits twinning as the dominating deformation mechanism: Cr: 13.0 to 30.0% by weight Mn: 2.0 to 10.0% by weight W: 2.0 to 18.0% by weight Fe: 5.0 to 15.0% by weight C: 0.002 to 0.5% by weight N: 0 to 0.2% by weight Si: 0 to 2.0% by weight Ni: 0 to 5.0% by weight wherein the aforementioned alloying components and manufacturing-related impurities add up to 100% by weight, and the following restrictions according to formulas (1) and (2) apply to the contents of nitrogen and carbon, and the following restrictions according to formula (3) apply to the contents of oxygen, phosphorus and sulfur: 0.003%?C+N?0.5% weight??(1) N/C(wt. %)?1.00 for 0.07%<C<0.15% (weight)??(2) O+P+S<0.10% weight??(3).
    Type: Grant
    Filed: June 5, 2013
    Date of Patent: September 12, 2017
    Assignee: BIOTRONIK AG
    Inventor: Bodo Gerold
  • Catheter shaft comprising welded tubes
    Patent number: 9682211
    Abstract: One embodiment of the invention relates to a catheter shaft comprising (i) a first tube made of an extrudable copolymer that has reactive groups, and (ii) a second tube made of a polymeric material, which can be welded to the first tube, wherein the polymeric material of the second tube can be welded to the first tube at a temperature ?200° C.
    Type: Grant
    Filed: March 7, 2013
    Date of Patent: June 20, 2017
    Assignee: Biotronik AG
    Inventors: Alwin Schwitzer, Hans Lang
  • Release device for releasing a medical implant from a catheter and catheter comprising a release device
    Patent number: 9649212
    Abstract: A release device for releasing a medical implant from an insertion device, having an indirect or direct clamping body for clamping the implant in the insertion device, the clamping device having a proximal end, and having a distal end, wherein the clamping body has at least one web, at least one extension and at least two clamping surface regions, wherein the extension is oriented substantially in the radial direction of the clamping body, and wherein the at least two clamping surface regions are substantially pointing toward one another and are aligned substantially parallel to one another, wherein the at least one web or the at least one extension has at least one of the two clamping surface regions, and wherein the at least two clamping surface regions and/or the at least one extension connect/connects to at least one region of the implant in the clamped state.
    Type: Grant
    Filed: November 28, 2012
    Date of Patent: May 16, 2017
    Assignee: BIOTRONIK AG
    Inventor: Amir Fargahi
  • Elastic cap for the protection of the distal end of a catheter having an inner and an outer hose
    Patent number: 9604032
    Abstract: An elastic cap for covering the distal end of a catheter having inner and outer hoses, characterized in that the cap consists essentially of an elastic material, has a cavity in which the distal end of the inner and the outer hose of a catheter can be received, and the cap has a first opening via which the cavity is accessible from the outside, wherein prior to receiving the distal end of the catheter, the first opening has a diameter which is not larger than the outer diameter of the inner hose of the catheter and wherein the first opening is elastically expandable to a diameter which corresponds to the outer diameter of the outer hose.
    Type: Grant
    Filed: April 26, 2012
    Date of Patent: March 28, 2017
    Assignee: BIOTRONIK AG
    Inventor: Amir Fargahi
  • Microstructured absorbable implant
    Patent number: 9504554
    Abstract: The production of microstructured surfaces in magnesium alloys, containing zinc as the major alloying element, in particular in absorbable implants such as stents, wherein microstructures in sizes of up to 5 ?m (micrometers) are generated on a magnesium alloy base body of the absorbable implant, for example of the absorbable stent, by way of optionally combined, pickling and electrochemical micropolishing processes, and allow better adhesion of a polymer coating (including higher break resistance) and higher corrosion resistance. The microstructured surface is produced out of the bulk material and exhibits no delamination from the base material during the mechanical deformation of the implant.
    Type: Grant
    Filed: January 2, 2014
    Date of Patent: November 29, 2016
    Assignee: BIOTRONIK AG
    Inventors: Ullrich Bayer, Monika Badendieck, Susanne Peters, Thomas Drobek, Okechukwu Anopuo
  • Implant and method for producing the same
    Patent number: 9486337
    Abstract: A method for producing a semifinished part (20) for an implant, in particular for an intraluminal endoprosthesis, which comprises the following steps: a) providing a first sleeve (11) from a first metallic material and at least one second sleeve (12, 13) from a second metallic material, b) arranging the first sleeve (11) and the at least one second sleeve (12, 13) into one another in such a manner that the sleeve combination (10) forms at least a press fit between said sleeves, and c) forming the sleeve combination (10) at an increased temperature by means of extrusion. The invention further includes a method for producing an implant, to a corresponding semifinished part or a corresponding implant, respectively.
    Type: Grant
    Filed: April 15, 2013
    Date of Patent: November 8, 2016
    Assignee: BIOTRONIK AG
    Inventors: Ullrich Bayer, Bernd Block, Daniel Lootz, Jan Hannemann, Nils Venohr
  • Implant and method for producing the same
    Patent number: 9480779
    Abstract: The present invention relates to an implant, in particular an intraluminal endoprosthesis, the body of which comprises at least predominantly a material with iron as the main constituent. For accelerating the degradation, the material comprises sulfur as first minor constituent with a concentration of more than 0.2% by weight and not more than 1% by weight, preferably not more than 0.5% by weight, and comprises as second minor constituent at least one element of the group which comprises calcium, manganese and magnesium. Furthermore, a method for producing such an implant is described.
    Type: Grant
    Filed: June 20, 2011
    Date of Patent: November 1, 2016
    Assignee: BIOTRONIK AG
    Inventor: Ullrich Bayer
  • Implant comprising an active-agent-containing coating covering the implant at least in sections
    Patent number: 9452243
    Abstract: The invention relates to an implant comprising an active-agent-containing coating which covers the implant at least in sections. The coating is composed of at least two subsections; a first subsection contains the at least one active substance, and a second subsection contains an auxiliary agent.
    Type: Grant
    Filed: November 29, 2011
    Date of Patent: September 27, 2016
    Assignee: BIOTRONIK AG
    Inventors: Matthias Gratz, Alexander Borck, Alexander Rzany, Robert Schmiedl, Matthias Fringes, Claus Harder
  • Stent made of a cobalt alloy
    Patent number: 9427500
    Abstract: A stent made entirely or partially of a cobalt alloy having the following composition: Co: 18.36-66.85% by weight Cr: 17.0-30.0% by weight Mn: 4.0-10.0% by weight W: 9.0-18.0% by weight Fe: 3.0-20.0% by weight C: 0.03-0.5% by weight N: 0.1-1.0% by weight Si: 0-2.0% by weight O: 0-0.05% by weight with the alloying components and production-related impurities adding up to 100% by weight and (i) a PRE value for corrosion resistance, which is derived from the weight percentages of the alloying components according to formula (1) PRE=[Cr]+1.65×[W]+30×[N]??(1) ranges between 34 and 89; and (ii) for the contents of nitrogen and carbon the following restrictions according to formula (2) and (3) apply 0.15?C+N?1.00??(2) 0.25?C+N?1.00??(3).
    Type: Grant
    Filed: June 10, 2013
    Date of Patent: August 30, 2016
    Assignee: BIOTRONIK AG
    Inventor: Bodo Gerold
  • Rapamycin 40-O-cyclic hydrocarbon esters, compositions and methods
    Patent number: 9408884
    Abstract: A new class of rapamycin 40-O-cyclic hydrocarbon esters is disclosed. The 40-O position of the rapamycin ester has the form 40-O—R, where R is C(O)—(CH2)n-X, n is 0, 1 or 2, and X is a cyclic hydrocarbon having 3-8 carbons, optionally containing one or more unsaturated bonds, and one or more linear (CH2)n) and/or cyclic (X) carbon atoms may have an OH or halide group. Also disclosed are therapeutic compositions and methods that employ the novel analogs.
    Type: Grant
    Filed: June 3, 2013
    Date of Patent: August 9, 2016
    Assignee: Biotronik AG
    Inventors: Ronald E. Betts, John Dang Nguyen
  • Method for preparing biological tissue
    Patent number: 9402934
    Abstract: A method for preparing tissue for medical applications, in particular tissue for use for an artificial heart valve, wherein the method has the steps of decellularizing the tissue by means of a detergent and subsequently cross-linking the collagen fibers of the tissue by means of a suitable cross-linking agent. At least one lipopeptide, such as surfactin, for example, is used as the detergent for decellularization.
    Type: Grant
    Filed: July 26, 2014
    Date of Patent: August 2, 2016
    Assignee: BIOTRONIK AG
    Inventors: Alexander Rzany, Wilhelm Erdbruegger
  • Material composition having reduced friction coefficient used for medical tubes
    Patent number: 9352072
    Abstract: Mixtures made of PE and COC, in particular for use in medical materials, so as to reduce the frictional forces. The mixtures comprising or consisting of PE and COC, wherein ?70% by weight, preferably ?90% by weight, and still more preferably 100% by weight, relative to the total mass of PE, of PE in the mixture is HDPE.
    Type: Grant
    Filed: May 16, 2013
    Date of Patent: May 31, 2016
    Assignee: Biotronik AG
    Inventor: Alwin Schwitzer
  • Medical valve implant for implantation in an animal body and/or human body
    Patent number: 9345572
    Abstract: A medical valve implant (10a, 10b) for implantation in an animal body and/or human body, comprising a base body (12a, 12b) that includes a collar (16a, 16b) extending in circumferential direction (14a, 14b), wherein the collar (16a, 16b) includes at least one first cell structure (18a, 18b) which is provided to form, in the intended end state, an intended inner cross section (24a, 24b) of base body (12a, 12b) that is matched to an intended outer cross section (20a, 20b) of an implant structure (22a, 22b).
    Type: Grant
    Filed: August 25, 2011
    Date of Patent: May 24, 2016
    Assignee: BIOTRONIK AG
    Inventors: Nils Le Cerf, Adalberto Sebastiao Camim
  • Implant, system formed of an implant and a catheter, and method for producing such a system
    Patent number: 9198781
    Abstract: An implant (10, 10?, 10?, 10?), in particular an intraluminal endoprosthesis, with an open-worked, hollow cylindrical and/or hollow conical main structure (11), wherein the main structure (11) can adopt a compressed state or an expanded state. To simplify final assembly by the doctor, a first tubular shaft (16, 16?) is additionally provided, on the outer face of which the main structure (11) is arranged in the compressed state, at least in portion, wherein the first shaft (16, 16?) has a first connection portion (20, 23), with which the first shaft (16, 16?) can be connected to the inner shaft (32, 32?, 32a, 32b) of a catheter (30, 30?, 30?). A corresponding system formed of an implant of this type and of a catheter (30, 30?, 30?) and a method for producing such a system.
    Type: Grant
    Filed: September 9, 2013
    Date of Patent: December 1, 2015
    Assignee: BIOTRONIK AG
    Inventors: Anita Bardill, Adrian Blaser, Aldo Jakob
  • RAPAMYCIN 40-O-CYCLIC HYDROCARBON ESTERS, COMPOSITIONS AND METHODS
    Publication number: 20150297662
    Abstract: A new class of rapamycin 40-O-cyclic hydrocarbon esters is disclosed. The 40-O position of the rapamycin ester has the form 40-O—R, where R is C(O)—(CH2)n-X, n is 0, 1 or 2, and X is a cyclic hydrocarbon having 3-8 carbons, optionally containing one or more unsaturated bonds, and one or more linear (CH2)n) and/or cyclic (X) carbon atoms may have an OH or halide group. Also disclosed are therapeutic compositions and methods that employ the novel analogs.
    Type: Application
    Filed: June 3, 2013
    Publication date: October 22, 2015
    Applicant: BIOTRONIK AG
    Inventors: Ronald E. Betts, John Dang Nguyen
  • Release device for disengaging a medical implant from a catheter and catheter having a release device
    Patent number: 9149380
    Abstract: A release device for disengaging a medical implant from an insertion device, in which the implant is releasable by a relative movement between a first insertion element and a second insertion element, comprising a body having a proximal end, which faces toward a user in the usage state, and a distal end, which is remote from the user in the usage state, a toothed rack having a first speed range and a second speed range being provided between the proximal end and the distal end, the toothed rack being provided to generate a targeted relative movement between the first insertion element and the second insertion element of the insertion device. Furthermore, the invention relates to an insertion device having such a release device.
    Type: Grant
    Filed: September 13, 2012
    Date of Patent: October 6, 2015
    Assignee: BIOTRONIK AG
    Inventor: Amir Fargahi
  • Implant with a surface layer having a topographic modification
    Patent number: 9138512
    Abstract: The present invention refers to an implant with a surface layer having a topographic modification. The topographic modification includes a line pattern with ridge and groove widths of 0.9 to 1.1 ?m and a ridge height of more than 0.9 ?m.
    Type: Grant
    Filed: August 25, 2011
    Date of Patent: September 22, 2015
    Assignee: Biotronik AG
    Inventors: Aldo Ferrari, Vartan Kurtcuoglu, Philipp Schoen, Jens Ulmer, Alexander Borck, Matthias Gratz, Alexander Rzany, Robert Schmiedl, Dimos Poulikakos, Bjoern Klocke
  • CRIMPING TOOL FOR A PROSTHETIC DEVICE AND METHOD FOR CRIMPING A PROSTHETIC DEVICE WITH A CRIMPING TOOL
    Publication number: 20150250587
    Abstract: A crimping tool and method for reducing an external dimension of a compressible prosthetic device, said the crimping tool comprising a first member comprising a first control surface collapsible between a first state and a second state, the first member having a first open end configured for introducing the prosthetic device when the first control surface is in the first state, and a second open end configured for allowing locking of the prosthetic device when introduced into the first member; an engagement portion that moves the first control surface from the first state to the second state; and an actuator portion for moving the first member along the longitudinal axis allowing the engagement portion to interact with the first member.
    Type: Application
    Filed: July 31, 2013
    Publication date: September 10, 2015
    Applicant: BIOTRONIK AG
    Inventors: Brian Murphy, Markus Hepke, Nils Le Cerf