Abstract: The disclosure relates to systems and methods for irrigated bipolar radiofrequency ablation. Some examples of the system include an elongate inner electrode assembly and an elongate outer electrode assembly. An irrigation path for irrigation fluid flow is defined between the outer surface of the inner electrode assembly and the outer surface of the outer electrode assembly.

Abstract: A clipping system includes an adapter configured to be mounted over an insertion device and a clip including first and second jaws movable between an insertion configuration and an initial deployed configuration. A first extending member is releasably coupled to the clip and movably connected to the adapter to permit a movement of the clip relative to the adapter from the insertion configuration to the initial deployed configuration. The first extending member is configured to permit withdrawal of the adapter away from the clip to place the system in a review configuration to enhance a visual observation of the clip. The first extending member is operable to retract the clip over the adapter so that the clip is forced open, freeing the clip from tissue on which it has been clipped. The first extending member is configured to release the clip therefrom in a final deployed configuration.

Abstract: A system for maintaining patency of a body lumen may include a first endoprosthesis configured to shift from a straightened configuration to a helical configuration defining a plurality of loops, and a second endoprosthesis configured to shift from a radially collapsed configuration toward a radially expanded configuration. The plurality of loops defines a passage having an inner diameter. At least a portion of the second endoprosthesis is disposed within the passage in the radially expanded configuration. A method of maintaining patency of a body lumen may include advancing a first endoprosthesis into a first body lumen in a straightened configuration, deploying the first endoprosthesis within the first body lumen in a helical configuration defining a plurality of loops, advancing a second endoprosthesis into the first body lumen in a radially collapsed configuration, and shifting the second endoprosthesis to a radially expanded configuration within the plurality of loops.

Abstract: An illustrative stent may comprise an elongated tubular member having a first end and a second end and an intermediate region disposed therebetween. The elongated tubular member configured to move between a collapsed configuration and an expanded configuration. The elongated tubular member may comprise at least one twisted filament, such as a knitted filament having a plurality of twisted knit stitches with intermediate rung portions extending between adjacent twisted knit stitches, or a plurality of helical filaments twisted with a plurality of longitudinal filaments.

Abstract: The present disclosure relates generally to the field of medical devices. In particular, the present disclosure relates to delivering a variable length stent within a patient. In one example, a stent may include a body comprising coils about a longitudinal axis of the stent and along the length of the stent between a proximal end and a distal end in a substantially helical pattern. The coils may define a lumen along the longitudinal axis through the center of the body. A distal tube may have a wall extending from the distal end of the body. A first aperture may extend through the wall of the distal tube into the lumen. A distal retention member may extend from the distal tube. A distal suture may have a mid-portion. The mid-portion may extend through the first aperture.

Abstract: A mandrel for forming a stent with a tapered profile and one or more anti-migration features includes a first stent shaping segment having a first diameter, a second stent shaping segment having a second diameter less than the first diameter and a tapered segment disposed therebetween. A third stent shaping segment is releasably securable to the second stent shaping segment and has a third diameter greater than the second diameter. One or more movable pins are outwardly extendable from corresponding apertures formed within the tapered segment. An actuation element is engagable with the first stent shaping segment and includes a tapered surface configured to engage the one or more movable pins and support the one or more movable pins extended from the corresponding apertures.

Abstract: A system includes a first cavity with an open upper proximal end and a distal end including a plurality of ports. A second cavity can be concentric with and advanceable through the open upper proximal end of the first cavity. The second cavity can include an open upper proximal end. A plunger can be on a distal end of the second cavity. The plunger can be configured to move a first constituent from the first cavity through at least one of the plurality of ports. A plunger rod can be advanceable through the open upper proximal end of the second cavity and configured to move a second constituent from the first cavity through at least one of the plurality of ports.

Abstract: A medical device includes a handle having a first end and a second end, a mixer positioned within the handle and an adapter coupled to the second end of the handle. A delivery needle includes a distal end, a proximal end, and a lumen extending from the distal end to the proximal end. The proximal end of the delivery needle is coupled to the first end of the handle. A sensor cable includes a distal end and a proximal end, and the proximal end of the sensor cable is positioned within the handle, and the distal end extends distally through the lumen of the delivery needle.

Abstract: A laser system may include a controller configured to direct a plurality of temporally spaced-apart electrical pulses to a device that optically pumps a lasing medium, and a lasing medium configured to output a quasi-continuous laser pulse in response to the optical pumping. The plurality of temporally spaced-apart electrical pulses may include (a) a first electrical pulse configured to excite the lasing medium to an energy level below a lasing threshold of the lasing medium, and (b) multiple second electrical pulses following the first electrical pulse. The quasi-continuous laser pulse is output in response to the multiple second electrical pulses.

Abstract: A cell encapsulation device for implantation in a body includes one or more cell encapsulation layers, each of the one or more cell encapsulation layers including at least one membrane and a guide tube. The at least one membrane is semipermeable. The least one membrane forms a chamber for encapsulating cells and at least one access port through the at least one membrane. The guide tube extends into the chamber from the at least one access port. The guide tube includes a porous wall along at least a portion of its length. The guide tube is capable of guiding movement of a catheter within the chamber.

Abstract: A device for aseptic delivery of biological material from a vial includes a tubular barrel, a filter assembly, and a dispersion assembly. The dispersion assembly is at least partially disposed within the tubular barrel. The dispersion assembly includes a dispersion element, a piston, and a one-way valve. The dispersion element is in fluid communication with the vial to disperse the biological material from the vial. The piston is disposed at the distal end of the dispersion assembly and is in sealing contact with the tubular barrel. The one-way valve forms a fluid passageway in fluid communication with the dispersion element and the tubular barrel. The one-way valve is configured to allow a flow of the dispersed biological material from the dispersion element, through the fluid passageway, and into the tubular barrel, and to prevent a flow of the dispersed biological material from the tubular barrel into the dispersion assembly.

Abstract: A medical dispensing device which includes a catheter, an applicator tip at a distal end of the catheter, the catheter and the applicator tip defining a lumen having a longitudinal axis and a distal opening, a plunger in the lumen and movable along the longitudinal axis, and a plurality of elements in the lumen proximal to the distal opening and distal to the plunger, the plurality of elements stacked along the longitudinal axis for dispersement of one element at a time through the distal opening via a force applied by the plunger.

Abstract: A fluid management and medical device system may include a fluid management system and a medical device. The fluid management system may include a pump configured to pump fluid to the medical device and a processing device configured to control the pump to maintain a target fluid flow range. The medical device may include an elongate shaft in fluid communication with the pump of the fluid management system, a pressure sensor, and a workstation in electronic communication with the pressure sensor and the processing device of the fluid management system. The processing device may be configured to adjust a fluid flow rate based on data received from the pressure sensor of the medical device and configured to verify the medical device is in a patient's body prior to adjusting the fluid flow rate based on the data received from the pressure sensor.

Abstract: A method of braiding a stent includes braiding a number of elongate filaments around a mandrel using tensioned braiding carriers without spooling the filaments to the tensioned braiding carriers to form a braided stent having atraumatic ends.

Abstract: A deployment system includes a sheath, a torque able shaft having a handle positioned at its proximal end, a detachable helical first suture anchor positioned at the shafts distal end and an elongate suture fixedly coupled to the suture anchor. The deployment system can be positioned at a first tissue, and the shaft rotated to advance the helical first suture anchor into engagement with the first tissue. The shaft is detached from the first suture anchor thereby deploying it at the first tissue location. Then, the deployment system is removed from the patient, and a second suture anchor is coupled to the distal end of the shaft. The deployment system is re-inserted into the patient and the distal end of the system is moved adjacent a second tissue location, and the process is repeated for a second suture anchor at the second tissue location.

Abstract: A medical device, comprising a handle, wherein the handle includes a movable body and a stationary body; an end cap, the end cap comprising an inner cap and an outer cap, wherein the inner cap is coupled to the movable body by a control element such that movement of the movable body relative to the stationary body extends the inner cap relative to the outer cap; and a patch disposed between the inner cap and the outer cap such that movement of the inner cap relative to the outer cap at least partially deploys the patch.

Abstract: According to one aspect, a fastening device may include a coupling body having (1) a portion configured to couple to a distal end of a medical device, (2) a cartridge holder, and (3) an anvil pivotably coupled to the cartridge holder. The cartridge holder and the anvil may extend distally from the portion and may be configured to extend distally of a distalmost face of the medical device when the portion is coupled to the distal end of the medical device. A flexible member may be configured to extend through a channel of the medical device. A fastener cartridge may be coupled to a distal end of the flexible member, including at least one fastener, and may be configured for releasable coupling to the cartridge holder.

Abstract: Devices, systems, and methods for a valve for a medical device. The valve may include a valve stem. An elongate body of the valve stem may include a first opening and a second opening fluidly coupled to one another via a lumen. The valve stem may include a first seal and a second seal extending circumferentially around the elongate body. The elongate body, the first seal, and the second seal may be formed from a single material. The single material may be a thermoplastic elastomer or other suitable material. The valve stem may include recessed portion proximate the seals of the valve stem to facilitate bending or flexing of the seals as the valve stem translates within a valve well.

Abstract: Devices, systems, and methods facilitating navigation through a body passage, particularly a tortuous body passage. An expandable member is mounted with respect to an element of the device or system and is shiftable from a delivery configuration to an expanded configuration. In the expanded configuration, the expandable member facilitates navigation of the device and/or system through a tortuous section of the body passage. The expandable member may include an expandable basket-like element formed of one or more elements shiftable from a generally elongated configuration when the expandable member is in the delivery configuration to a curved or bowed configuration when the expandable member is in the expanded configuration. Additionally or alternatively, the expandable member may include an inflatable balloon. The system and method may include delivering a device such as a locator element to a target site to be identified from a remote location.