Abstract: Method for applying loose, free-flowing powder compositions to the skin from a dispensing container utilizing a dispensing ball or roller containing filamentous hair-like projections over its exterior surface, and dry antiperspirant powder compositions based on particulate aluminum and/or zirconium chlorohydrate as the active antiperspirant ingredient including minor amounts of a surfactant vehicle to aid in maintaining the powder on the skin after contact therewith.

Abstract: Foam products are disclosed which are produced by incorporating active materials, utilizing in situ methods, into the cell structure of hydrophillic polyurethane foams. The products obtained are characterized by a controlled rate of release of the active material from the foam structure.

Abstract: A novel chemical compounds of the formula ##STR1## wherein R is hydrogen or branched or straight chain lower alkyl of from 1-6 carbon atoms as well as methods for preparing such compounds.

Abstract: Basic dithienyl compounds are prepared by hydrolysis of a compound of the formula ##STR1## wherein R is hydrogen or lower alkyl.

Abstract: The compound 7-chloro-2-methyl-3,3a-dihydro-2H,9H-isoxazolo(3,2-b)(1,3)-benzoxazin-9-on e is produced by reacting a mixture of tetrahydrofuran and crotonaldehyde with 5-chlorosalicylhydroxamic acid. The compound has demonstrated utility as a uricosuric agent.

Abstract: A method for lowering serum uric acid is disclosed which comprises administering to a human for its uricosuric activity a pharmaceutical composition comprising 7-chloro-2-methyl-3,3a-dihydro-2H,9H-isoxazolo (3,2-b) (1,3)-benzoxazin-9-one.7-chloro-2-methyl-3,3a-dihydro-2H,9H-isoxazolo (3,2-b) (1,3) benzoxazin-9-one is a useful compound having valuable pharmacological properties, for example, it is a valuable anti-inflammatory agent, as evidenced by its ability to inhibit the local edema formation characteristic of inflammatory states when administered systemically to warm-blooded animals.

Abstract: A process for the production of 2-methyl-2-sec. butyl-1,3-propanediol from crotyl alcohol is disclosed. The diol obtained is useful in the manufacture of 2-methyl-2-(1-methylpropyl)-1,3-propanediol dicarbamate a valuable antihypertensive agent.

Abstract: A method for suppressing the release of histamine from sensitized leukocytes in warm blooded animals which comprises administering internally to said animals compounds of the formula: ##STR1## wherein n is a whole integer from 1 to 4; X is halogen and Z is COOH, CH.sub.2 OR or ##STR2## R being a lower alkyl chain of from 1 to 6 carbon atoms and pharmaceutically acceptable salts of those compounds wherein Z is COOH, in sufficient amount to suppress the release of histamine from said cells.

Abstract: Novel 2,3-disubstituted-1,2,4-benzothiadiazine 1,1-dioxides of the formula: ##STR1## wherein X is hydrogen or chlorine. The novel compositions have been obtained by an unexpected side chain chlorination and have been found to be useful in medicinal chemistry as antihypertensives.

Abstract: Chemical compounds of the formula: ##STR1## wherein X is hydrogen, hydroxy, halogen, lower alkyl, lower alkoxy, nitro, amino, acetamido, sulfonamido or trifluoromethyl, and each R is selected from the group consisting of hydrogen and lower alkyl. Said compounds have valuable anti-inflammatory activity in standard laboratory animals.

Abstract: N-methyl-4-piperidinyl.alpha.-benzoyloxy-.alpha.-cyclopentylphenylacetate. The novel ester in the form of its free base or as a salt has been found to be an effective inhibitor of perspiration.

Abstract: Novel alkylamine fluorophosphates of the formula: ##STR1## wherein R is a linear or branched alkyl group containing 1-20 carbon atoms; R.sub.1 is lower alkyl or hydrogen, R.sub.2 is alkyl or hydrogen; X is 1 or 2; Y is 1 when X=1; Y is 1 or 2 when X=2; m and n are positive whole integers whose sum is 3. When R, R.sub.1 and R.sub.2 are alkyl they can be substituted with an hydroxy group. The novel fluorophosphates have been found to be effective in reducing the acid solubility of tooth enamel.

Abstract: A valve-actuated aerosol package for separately storing and simultaneously dispensing in the form of a spray or stream a plurality of flowable materials. The package comprising a self-standing first container closed at one end with a dispensing valve at its opposite end and forming a first chamber. A piston diaphragm pressurably mated with the inner walls of the first chamber and dividing said chamber into an upper and lower chamber, a second coaxially mounted container within said upper chamber such that liquid cannot pass between said second container and said upper chamber. The valve-actuated aerosol package being operative to dispense flowable materials from said upper chamber and said second container separately and simultaneously or as a mixture through a dispensing nozzle.

Abstract: An apparatus and a method are provided for assembling micro-filter units having a barrel, a plug adapted to be inserted in the barrel, and a filter disc clamped between the barrel and the plug, which are characterized in that the filter disc is punched out and seated in the barrel in a single stroke of a punch.

Abstract: A plastic puck having a magnetic ring secured to its bottom is employed for magnetically conveying a can. The interior of the puck preferably includes deflectable plastic fins for securely holding the can within the puck.