Abstract: The invention provides a liquid crystal compound which has stability to heat, light and so forth, shows liquid crystal phases in a wide temperature range, and has a small viscosity, an appropriate optical anisotropy, a large dielectric anisotropy, and an excellent compatibility with other liquid crystal compounds. The invention provides a liquid crystal composition which has an appropriate optical anisotropy, an appropriate dielectric anisotropy, a low threshold voltage, and a high maximum temperature and a low minimum temperature of a nematic phase. The invention provides a liquid crystal display device which has a short response time, a small power consumption, a small driving voltage, and a large contrast, and can be used in a wide temperature range. The liquid crystal compound is a halogeno-benzene derivative having a trifluoropropenyl group or trifluoropropynyl group at a side chain, such as, for example, trans-4?-[3,5-difluoro-4-(3,3,3-trifluoropropenyl)phenyl]-trans-4-propylbicyclohexyl.

Abstract: The invention includes compounds represented by Formula (1): wherein R represents hydrogen or methyl; A represents alkylene having from 1 to 12 carbon atoms, wherein in the alkylene, arbitrary —CH2— may be replaced by —O—, —S—, —CH?CH—, —CO—, —COO— or —OCO—; X and Y each independently represent an aromatic ring or a cyclohexane ring, wherein in the rings, arbitrary hydrogen may be replaced by alkyl having from 1 to 3 carbon atoms; Z independently represents a single bond, —O—, —S—, —COO—, —OCO—, —CON(R1)— or —N(R1)CO—, wherein R1 represents hydrogen or methyl; and m represents an integer of from 0 to 3.

Abstract: A polymer containing: a constitutional unit A that is derived from fluorosilsesquioxane having one addition polymerizable functional group in a molecule; a constitutional unit B that is derived from organopolysiloxane having an addition polymerizable functional group; and a constitutional unit C that is derived from an addition polymerizable monomer and has a group having a polymerizable unsaturated bond on a side chain, and optionally containing a constitutional unit D that is derived from an addition polymerizable monomer other than the fluorosilsesquioxane having one addition polymerizable functional group in a molecule, the organopolysiloxane having an addition polymerizable functional group and the addition polymerizable monomer having a functional group capable of introducing a group having a polymerizable unsaturated bond.

Abstract: Disclosed are a detection/quantification kit and a detection/quantification method for detecting/quantifying an analyte rapidly at a low cost and in a simple manner. Specifically, disclosed is a kit for detecting an analyte in a sample, comprising a first conjugate and a second conjugate, wherein the first conjugate comprises a first substance comprising a stimuli-responsive polymer and a first affinity substance having affinity for the analyte and bound to the first substance, and the second conjugate comprises a second substance carrying an electrical charge and a second affinity substance having affinity for the analyte and bound to the second substance. The first and second affinity substances can bind to different sites on the analyte simultaneously.

Abstract: A liquid crystal composition is described, which satisfies at least one characteristic among high maximum temperature of a nematic phase, low minimum temperature of a nematic phase, small viscosity, large optical anisotropy, large dielectric anisotropy, large specific resistance, high stability to ultraviolet light, high stability to heat and so on, or is properly balanced regarding at least two of the characteristics. To provide an AM device having short response time, large voltage holding ratio, large contrast ratio, long service life and so forth, the liquid crystal composition has a nematic phase and contains a specific three-ring compound having a large optical anisotropy as a first component, a specific four-ring compound having a large dielectric anisotropy as a second component, and a specific two-ring compound having a particularly small viscosity as a third component. A liquid crystal display device containing the liquid crystal composition is also described.

Abstract: A liquid crystal composition having a nematic phase that includes two components, wherein the first component is at least one compound selected from the group of compounds represented by formulas (1-1) and (1-2), and the second component is at least one compound selected from the group of compounds having a group represented by formulas (2-1) and (2-2): wherein R1 is alkyl having 1 to 12 carbons; Z1 and Z2 are each independently a single bond or ethylene; X1 is independently fluorine, chlorine, OCF3 or OCF2H; Y1 is independently hydrogen or fluorine; and n is independently 1 or 2.

Abstract: A liquid crystal composition having a nematic phase that includes two components, wherein the first component is a specific four-membered ring compound having a large maximum temperature, and the second component is a specific four-membered ring compound having a large dielectric anisotropy and a large optical anisotropy, and a liquid crystal display device containing the composition.

Abstract: The invention provides an alkali soluble polymer including a specific vinylketone phenol and a derivative thereof as radical polymerizable monomers and a positive working photosensitive resin composition containing the alkali soluble polymer and a photosensitizing agent. According to the invention, there can be provided an alkali soluble resin having high solvent resistance, high water resistance, high acid resistance, high alkali resistance, high thermal resistance, high transparency, excellent adhesiveness with a substrate, and the like and useful for the formation of a patterned resin film obtained by developing in an aqueous alkali solution and a positive working photosensitive resin composition including such an alkali soluble resin.

Abstract: A protein according to the invention can be used to detect or measure calcium ions is provided. Further the protein is useful as a reporter protein or a luminescence marker. A polynucleotide according to the invention is also useful as a reporter gene.

Abstract: A nematic liquid crystal compound represented by any one of formulas (a-1) to (a-6): in formulas (a-1) to (a-6), Ra and Rb are each independently hydrogen or alkyl having 1 to 10 carbons, provided that in the alkyl, —CH2- may be replaced by —O—, —(CH2)2- may be replaced by —CH?CH—, and hydrogen may be replaced by a halogen; ring A1 and ring A2 are each independently trans-1,4-cyclohexylene or 1,4-phenylene, provided that in these rings hydrogen may be replaced by a halogen, and in the case where the ring is trans-1,4-cyclohexylene, —CH2- may be replaced by —O—, and —CH2CH— may be replaced by —CH?C—; and Z1 and Z2 are each independently a single bond, —COO—, —OCO—, —OCH2-, —CH2O— or —CH2CH2-, provided that in formula (a-3), in the case where ring A2 is trans-1,4-cyclohexylene, Z2 is a single bond, —COO—, —OCO—, —OCH2- or —CH2O—, in the case where Ra is —C3H7, Rb is —OC2H5, and Z2 is a single bond, ring A2 is trans-1,4-cyclohexylene, 1,3-dioxane-2,5-diyl, 2-fluoro-1,4-phenylene, 3-fluoro-1,4-phenylene, 2-fl

Abstract: A thrombin mutant in which at least serine at position 205 among amino acids in the active center of the thrombin B chain has been replaced with another amino acid, and further at least one of the following replacements have been introduced: (I) replacement of arginine at position 89 in the B-chain with another amino acid; (II) replacement of threonine at position 69 or serine at position 22 in the B-chain with another amino acid; (III) replacement of alanine at position 200 in the B-chain with another amino acid; and (IV) replacement of lysine at position 65 in the B-chain with threonine.

Abstract: A production process for a silicon compound represented by Formula (6), characterized by reacting a compound represented by Formula (4) with a compound represented by Formula (5): wherein all of the variables are defined in the specification.

Abstract: A platelet aggregation inducing substance containing as an active ingredient a polypeptide having a peptide fragment represented by formula (1) (component A): -(Pro-X-Gly)n- ??(1) wherein X represents Pro or Hyp; and n represents an integer of from 20 to 5,000.

Abstract: The invention is generally related to a polymer/liquid crystal composite, which includes a liquid crystal material which exhibits an optically isotropic liquid crystal phase in the temperature range of approximately 5° C. or more in the elevated temperature process but does not exhibit a nematic phase; and a polymer, and which is used for an element driven in a state of the optically isotropic liquid crystal phase.

Abstract: Disclosed is a modified electroconductive polymer material, which comprises a metal filled in a space between the chains of an electroconductive polymer. The metal is oxidized (partially formed as a hydroxide) through a chemical reaction between three substances consisting of the metal, a cation radical/dication, and absorbed water. The metal has a work function less than that of the electroconductive polymer. The contact between the metal and the electroconductive polymer is kept in the state of coexistence between three substances consisting of the metal, the cation radical/dication and the absorbed water. This allows an electroconductive polymer material to have enhanced durability against oxidation/reduction, and controlled conductivity.

Abstract: The invention provides a liquid crystal composition having an optically isotropic liquid crystal phase used in an element driven in a state of an optically isotropic liquid crystal phase, which comprises a compound I having the clearing point T1 and a compound 2 having the clearing point T2, and which has the clearing point Tx, wherein the liquid crystal composition comprises 10 to 80 wt % of compound 1 and 20 to 90 wt % of compound 2, and wherein the clearing point T1, the clearing point T2 and the clearing point Tx of the liquid crystal composition satisfy the following conditions: T1>T2 T1?Tx?100° C.

Abstract: The liquid crystal composition includes at least one compound selected from a group of compounds represented by formula (1) as a first component, has a positive dielectric anisotropy, and has a nematic phase, and a liquid crystal display element containing the composition: wherein R11 and R12 are alkyls having different carbon numbers.

Abstract: The liquid crystal composition includes at least one compound selected from a group of compounds represented by formula (1) as a first component, has a positive dielectric anisotropy, and has a nematic phase, and a liquid crystal display element containing the composition: wherein R11 and R12 are alkyls having different carbon numbers.

Abstract: A liquid crystal composition is provided that satisfies at least one characteristic among the characteristics such as a high maximum temperature of a nematic phase, a low minimum temperature of a nematic phase, a small viscosity, a large optical anisotropy, a large dielectric anisotropy, a large specific resistance, a high stability to ultraviolet light and a high stability to heat, or is properly balanced regarding at least two characteristics. An AM device is provided that has a short response time, a large voltage holding ratio, a large contrast ratio, a long service life and so forth. The liquid crystal composition having a nematic phase contains a specific five-ring compound having a large maximum temperature as the first component, a specific compound having a small viscosity as the second component, and a specific four-ring compound having a high maximum temperature as the third component. The liquid crystal display device contains the liquid crystal composition.

Abstract: A liquid crystal compound is provided that has excellent characteristics, such as a negatively large dielectric anisotropy. A liquid crystal composition containing the compound, and a liquid crystal display device containing the composition are also provided. A compound having the three factors, i.e., (1) a tetrahydropyran ring, (2) terminal alkenyl chain and (3) exhibits excellent characteristics including a negatively large dielectric anisotropy (??). The use of the compound having the characteristics provides an excellent liquid crystal composition and an excellent liquid crystal display device.