Patents Assigned to Chung Yuan Christian University
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Patent number: 10648903Abstract: A photothermal deflection measuring system includes a substrate, a detecting light source, a detecting unit, and a processor. The substrate includes a plurality of positioning structures, on each of which supports a cell emitting heat outside a surface thereof. The detecting light source is utilized to project a detecting light passing through a specific position outside the surface whereby the detecting light is deflected due to a thermal gradient caused by the emitted heat. The detecting unit is arranged at a side of the cell for receiving the deflected detecting light thereby generating an optical deflection signal corresponding to a deflection of the deflected detecting light. The processor is configured to receive the optical deflection signal, analyze the optical deflection signal and determine a heat value corresponding to the specific position out side the surface of the cell according to the optical deflection signal.Type: GrantFiled: July 26, 2018Date of Patent: May 12, 2020Assignee: CHUNG YUAN CHRISTIAN UNIVERSITYInventors: Tzong-Rong Ger, Shyh-Liang Lou, Szu-Yu Lin
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Patent number: 10644308Abstract: An electrode material of a sodium-ion battery, a method of manufacturing the same, and an electrode of the sodium-ion battery are provided. The electrode material of the sodium-ion battery includes an oxide comprising sodium, vanadium, and phosphorus represented by formula 2 below: Na3+x2?yV2(PO4?yFy)3, wherein 0.01?x2?0.99 and 0.01?y?0.3.Type: GrantFiled: April 2, 2018Date of Patent: May 5, 2020Assignee: Chung Yuan Christian UniversityInventors: Wei-Jen Liu, Yi-Tang Chiu, Rasu Muruganantham
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Patent number: 10639372Abstract: A medical nanoparticle includes a core, an outer lipid layer, an inner lipid layer, a photosensitizer, and a nucleic acid. The core includes a bio-degradable ionic precipitate (BIP). The inner lipid layer is between the core and the outer lipid layer. The photosensitizer is between the inner lipid layer and the outer lipid layer, and the nucleic acid is at the surface of the core.Type: GrantFiled: June 16, 2016Date of Patent: May 5, 2020Assignee: CHUNG YUAN CHRISTIAN UNIVERSITYInventors: Leaf Huang, Yih-Chih Hsu, Gang Zheng, Chia-Hsien Yeh
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Publication number: 20200126234Abstract: Disclosed herein are methods for predicting the reprogramming process of cells from a microscopic image of one or more cells. According to some embodiments, the method includes capturing an image of region of interest (ROI) of every pixel of the microscopic image, followed by processing the ROI image with a trained convolutional neural network (CNN) model and a trained long short-term memory (LSTM) network so as to obtain predicted probability maps. Also disclosed herein are a storage medium and a system for executing the present methods.Type: ApplicationFiled: December 18, 2019Publication date: April 23, 2020Applicants: Chung Yuan Christian University, RIKENInventors: Hideo Yokota, Kuniya Abe, Ming-Dar TSAI, Slo-Li CHU, Yuan-Hsiang CHANG
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Patent number: 10628639Abstract: A method of cable sensing data collection applicable to an electronic apparatus having a counter array is provided. The electronic apparatus is for detecting a cable including a plurality of sensors and a plurality of RFID tags, where each of the RFID tags is used to receive cable sensing data of the cable obtained by the sensors. The method includes: scanning each of the RFID tags to retrieve the cable sensing data, where the cable sensing data includes a tag identifier of the RFID tag; converting the tag identifier to a plurality of array addresses through a plurality of hash functions; and transmitting the cable sensing data to a cloud platform according to whether a plurality of elements of the array addresses in the counter array having a zero or not. In addition, an electronic and a chip using the method are also provided.Type: GrantFiled: December 4, 2018Date of Patent: April 21, 2020Assignee: Chung Yuan Christian UniversityInventors: Yu-Kuen Lai, Tzu-Hang Lin, Chung-Hsiang Cheng, Ku-Yeh Shih
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Patent number: 10615416Abstract: A negative electrode material applied to a lithium battery or a sodium battery is provided. The negative electrode material is composed of a first chemical element, a second chemical element and a third chemical element with an atomic ratio of x, 1?x, and 2, wherein 0<x<1, the first chemical element is selected from the group consisting of molybdenum (Mo), chromium (Cr), tungsten (W), manganese (Mn), technetium (Tc) and rhenium (Re), the second chemical element is selected from the group consisting of Mo, Cr and W, the third chemical element is selected from the group consisting of sulfur (S), selenium (Se) and tellurium (Te), and the first chemical element is different from the second chemical element.Type: GrantFiled: November 15, 2017Date of Patent: April 7, 2020Assignee: Chung-Yuan Christian UniversityInventors: Chun-Chuen Yang, Wei-Jen Liu, Yung-Hsiang Tung, Irish Valerie Buiser Maggay, Cheng-Wei Kao, Tung-Chi Tsai
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Patent number: 10598619Abstract: A thermal properties measuring device is for measuring a thermal property of an object to be measured. The thermal properties measuring device includes a heating element, a measurement window, and at least one thermometer. The heating element is configured to be heated to a first temperature. The measurement window and the heating element are disposed according to a specific geometric relationship. The measurement window is configured to provide a heat transfer path between the object and the heating element. The thermometer is configured to measure an initial temperature of the to-be-measured object, and to measure a measured temperature after the heating element is heated. The measured temperature of the object is different from the initial temperature of the object. The thermal property of the object is associated with the specific geometric relationship, the first temperature, the initial temperature, the measured temperature and an environment temperature.Type: GrantFiled: December 4, 2017Date of Patent: March 24, 2020Assignee: Chung Yuan Christian UniversityInventors: Po-Ting Lin, Shu-Ping Lin, Wei-Hao Lu, Yu-Hsien Tu
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Patent number: 10586327Abstract: Disclosed herein are methods for identifying cells undergoing reprogramming and reprogrammed cells from a fluorescence microscopic image of one or more cells. According to some embodiments, the method includes an image processing step, a cell detection step, and, optionally, a clustering step.Type: GrantFiled: February 13, 2018Date of Patent: March 10, 2020Assignees: CHUNG YUAN CHRISTIAN UNIVERSITY, RIKENInventors: Yuan-Hsiang Chang, Hideo Yokota, Kuniya Abe, Ming-Dar Tsai
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Patent number: 10564011Abstract: A linear piezoelectric motor and a slider drive system thereof are disclosed. The linear piezoelectric motor includes a piezoelectric ceramic element and a base structure. The piezoelectric ceramic element includes a first region, a second region and an interval region located between the first and the second region, wherein the first and the second region may be formed by a first and a second power signal supplied by a power supply to form a first and a second standing wave, respectively. The interval region is a quarter wavelengths. The first and the second standing wave have a phase difference so as to form a traveling wave. The base structure disposes the piezoelectric ceramic element and has a pectinate structure to increase the amplitude of the first and the second standing wave, thereby enabling the piezoelectric motor to be driven.Type: GrantFiled: January 24, 2018Date of Patent: February 18, 2020Assignee: CHUNG-YUAN CHRISTIAN UNIVERSITYInventors: Yung Ting, Sheuan-Perng Lin, Chien-Hsiang Wu
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Patent number: 10538545Abstract: Disclosed herein are novel compounds of formula (I) and (II), each of which may serve as a reagent to deliver nitric oxide (NO) and a therapeutic agent to treat NO-associated diseases. Also disclosed are a pharmaceutical composition comprising the compound of formula (I) or (II), a composite material comprising the compound of formula (I) or (II), and the uses thereof.Type: GrantFiled: January 24, 2017Date of Patent: January 21, 2020Assignee: Chung Yuan Christian UniversityInventors: Tsai-Te Lu, Hsiao-Wen Huang, Chia-Her Lin, Yu-Ting Tseng, Wen-Feng Liaw, Hsi-Ya Huang, Show-Jen Chiou
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Patent number: 10515619Abstract: Disclosures of the present invention describe a portable smart electronic device, which consists of several first reference microphones, a first loudspeaker, a first error microphone, several of second reference microphones, a second loudspeaker, a second error microphone, and a noise controlling module. Both the first error microphone and the second error microphone are set to have a noise detection direction and face to a first region near to a right ear and a second region near to a left ear, respectively. Therefore, the noise detection direction and an audio broadcasting direction of both the first loudspeaker and the second loudspeaker have a same progress direction. By such arrangement, this portable smart electronic device can be operated to adaptively provide an anti-noise audio to the first region and the second region for establishing a quiet zone in both the two regions by attenuating various environment noises.Type: GrantFiled: May 2, 2019Date of Patent: December 24, 2019Assignee: Chung Yuan Christian UniversityInventors: Cheng-Yuan Chang, Sen-Maw Kuo
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Publication number: 20190365852Abstract: Disclosed herein are recombinant baculoviruses suitable for introducing an exogenous gene into a pest insect, particularly, disease-transmitting mosquitos. The recombinant baculovirus is characterized in having a promotor that is any of a HzNV-1 viral early expressing gene pag1, a ceropin gene b1, a defensin gene a4, or hp70 gene; and an exogenous gene operably linked thereto the promoter. Also disclosed herein is a method of introducing an exogenous gene into a pest insect. The method includes transducing the pest insect with a recombinant baculovirus without suppressing the production of microRNAs (miRNAs) in the pest insect, wherein the recombinant baculovirus comprises a promoter of pag1, cecropin b1, defensin gene a, or hp70.Type: ApplicationFiled: May 30, 2018Publication date: December 5, 2019Applicants: Academia Sinica, Chung Yuan Christian University, National Defense Medical CenterInventors: Yu-Chan CHAO, Nenavath Gopal NAIK, Tzong-Yuan WU, Chang-Chi LIN, Szu-Cheng KUO
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Patent number: 10494557Abstract: The present invention relates to a method of preparing nitrogen-doped graphene, comprising: mixing at least one solid-state nitrogen containing precursor with a graphene to form a mixture, and sintering the mixture under a reducing atmosphere to obtain the nitrogen-doped graphene. The present invention further provides a method of producing a composite heat dispatching plate coated with nitrogen-doped graphene film, comprising: mixing a nitrogen-doped graphene obtained aforementioned with a polymer bonding agent to form a mixture slurry, coating the mixture slurry onto at least one surface of a metal substrate to form a composite material, drying the composite material, and obtaining the composite heat dispatching plate with a film of nitrogen-doped graphene. Structural defects of graphene lattices are reduced during doping process so that crystallinity and thermal conductivity are improved.Type: GrantFiled: May 30, 2016Date of Patent: December 3, 2019Assignee: Chung Yuan Christian UniversityInventors: Wei Jen Liu, Zheng Zhe Xie, Jun Shen
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Publication number: 20190352562Abstract: Disclosed herein are composite fluorescent gold nanoclusters with high quantum yield, as well as methods for manufacturing the same. According to some embodiments, the composite fluorescent gold nanocluster includes a gold nanocluster and a capping layer that encapsulates at least a portion of the outer surface of the gold nanocluster. The capping layer includes a matrix made of a benzene-based compound, and multiple phosphine-based compounds distributed across the matrix.Type: ApplicationFiled: May 17, 2018Publication date: November 21, 2019Applicant: Chung Yuan Christian UniversityInventors: Cheng-An LIN, Cheng-Yi HUANG, Chia-Hui LIN, Tzu-Yin HOU
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Publication number: 20190308354Abstract: An injection molding apparatus including a mold, an injection device and a specific volume sensing module is provided. The injection device is adapted to inject a material into the mold. At least parts of the specific volume sensing module are disposed at the mold, wherein the specific volume sensing module is adapted to sense an actual specific volume of the material in the mold. In addition, an injection molding method is also provided.Type: ApplicationFiled: June 25, 2018Publication date: October 10, 2019Applicant: Chung Yuan Christian UniversityInventors: Shia-Chung Chen, Yung-Hsiang Chang, Ying-Fan Lou
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Patent number: 10435425Abstract: Disclosed herein a sialyl donor and its use for the synthesis of gangliosides. The sialyl donor has the structure of, wherein, R1 and R2 are independently benzoyl, toluenesulfonyl, pivaloyl or acetyl optionally substituted with a halogen; and R3 is acetyl or —(O)CCH2OH. In one preferred embodiment, in the sialyl donor of formula (I), R is acetyl. Also disclosed herein is a method of synthesizing a sialoside. The method comprises steps of: coupling the sialyl donor of formula (I) with a glycosyl acceptor having a primary hydroxyl group in the presence of N-iodosuccinimide (NIS) and trifluoromethanesulfonic acid (TfOH) under suitable conditions; and isolating the sialoside, which has an ?-glycosidic linkage. According to preferred embodiments, the coupling is conducted in a solvent selected from the group consisting of, CH3CN, CH3Cl, and CH2Cl2 at a temperature between ?20° C. to ?60° C.Type: GrantFiled: July 14, 2018Date of Patent: October 8, 2019Assignee: Chung Yuan Christian UniversityInventors: Yow-Fu Tsai, Yu-Fa Wu
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Patent number: 10437205Abstract: A control system and a control method of manufacturing injection molding products are provided. The control system includes an injection molding machine, an information input interface, a computing server and a data conversion device. At first, product information is inputted through the information input interface. The product information is transmitted to the computing server, and then the computing server determines injection molding parameters according to the product information. The injection molding parameters are transmitted to the information input interface. After data conversion through the data conversion device, the injection molding machine is controlled to manufacture the injection molding products according to the converted injection molding parameters.Type: GrantFiled: October 2, 2015Date of Patent: October 8, 2019Assignee: CHUNG YUAN CHRISTIAN UNIVERSITYInventors: Shia-Chung Chen, Chia-Yen Tseng, Yung-Hsiang Chang, Kuan-Hua Lee
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Publication number: 20190296330Abstract: A method of fabricating an anode material for a secondary battery includes following steps. A carbon-containing biomass material is provided. The carbon-containing biomass material is mixed with a solid-state nitrogen-containing precursor via a solid-phase mixing method to form a mixture. A sintering process is performed on the mixture to form a nitrogen-doped biomass carbon.Type: ApplicationFiled: May 24, 2018Publication date: September 26, 2019Applicant: Chung Yuan Christian UniversityInventors: Wei-Jen Liu, Shing-Yu Tsai
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Patent number: 10423819Abstract: Disclosed herein are methods for analyzing cell kinematics in a nucleated cell culture from a time-series sequence of multiple fluorescence microscopic images of the nucleated cell culture. The method includes the steps of, (a) identifying every cell nucleus in each fluorescence microscopic image; (b) identifying every cell cluster using the cell nuclei identified in the step (a); and (c) tracking the cells and/or cell clusters using the cell nuclei and cell clusters identified for the fluorescence microscopic images in steps (a) and (b) respectively.Type: GrantFiled: October 31, 2017Date of Patent: September 24, 2019Assignee: Chung Yuan Christian UniversityInventors: Yuan-Hsiang Chang, Hideo Yokota, Kuniya Abe, Ming-Dar Tsai
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Publication number: 20190262799Abstract: A Mg-doped alumina aerogel and a manufacturing method thereof are provided. The Mg-doped alumina aerogel is a three-dimensional cross-linked network structure including a plurality of magnesium atoms, a plurality of aluminum atoms, a plurality of oxygen atoms, and a plurality of hydrogen atoms. The three-dimensional cross-linked network structure has a —Mg—O—Al— bond at least on the main chain.Type: ApplicationFiled: May 2, 2018Publication date: August 29, 2019Applicant: Chung Yuan Christian UniversityInventors: Yi-Feng Lin, Yong-Jie Lin