Abstract: Coating compositions having reproducible properties and high scratch resistance contain an ethylenically unsaturated binder and particles functionalized with an alkoxysilane, the silicon atom of which is spaced from an electron withdrawing group by a methylene group.

Abstract: The invention concerns a homoserine transsuccinylase having at least one mutation compared to a wild-type homoserine transsuccinylase and reduced sensitivity towards a L-methionine or SAM, compared to the wild-type enzyme. The latter comprises an amino acid sequence including a partial AspGlyXaaXaaXaaThrGlyAlaPro sequence between position 90 and position 115 and a partial TyrGlnXaaThrPro sequence between position 285 and position 310, position 1 of the amino acid sequence corresponding to the initial methionine. The invention is characterized in that the mutation is a substitution of the aspartate in the partial AspGlyXaaXaaXaaThrGlyAlaPro sequence, or a substitution of the tyrosine in the partial TyrGlnXaaThrPro sequence.

Abstract: Both flexible and rigid foams may be prepared by reacting di- or polyisocyanates with organopolysiloxanes which are prepared by reaction of silanol-terminated organopolysiloxanes with organosilicon compounds containing alkyleneoxy or alkylenamino groups bonded on both ends to silicon, thus resulting in organopolysiloxanes having 95% or more of aminoalkyl or hydroxyalkyl terminal groups.

Abstract: In the preparation of phosphonatosilanes by reaction of organophosphites with halocarbon-functional silanes, the safety of the reaction is markedly increased while increasing space/time yield by continuously or periodically withdrawing reaction mixture, freeing the withdrawn mixture of phosphonatosilane product, and recycling the product-depleted remainder back to the reaction. Operation at temperatures of 100° C. or lower is made possible by this process.

Abstract: Particles useful in curable coating systems are functionalized on their surface with a blocked isocyanate functionality. The blocked isocyanate is generated by reacting an organosilane having an oxygen, sulfur or nitrogen atom a to the silyl group, or having a cyclic structure containing N or O in the ring, attached directly to silicon.

Abstract: Compositions which are crosslinkable contain an alkoxysilyl or hydroxyl-functional binder and functionalized particles prepared by reacting a filler having reactive groups on its surface with an alkoxysilane in which an alkoxysilyl group is linked to a heteroatom by an optionally substituted methylene spacer. The particle may react with the alkoxy group of the alkoxysilane or with a group containing the heteroatom of the alkoxysilane to functionalize the particles.

Abstract: An enantioselective method for producing optically active 3-alkyl carboxylic acids comprises transforming an optically active secondary alcohol into an optically active, activated compound by introducing a leaving group; reacting the activated compound with a malonic acid derivative to obtain an optically active, alkylated malonic acid compound, the reaction taking place exclusively in ether and/or carboxylic acid ester solvents and one or more aprotic polar solvents or alcohols as a cosolvent in a maximum proportion of 30 volume percent of total solvent, wherein the added cosolvent is not hexamethyl phosphoric acid triamide; the malonic acid compound is hydrolyzed if necessary to obtain the corresponding acid; and the corresponding acid is decarboxylated.

Abstract: The invention relates to a novel process for hydroxymethylating noncyclic ?,?-dialkylcarboxylic acid derivatives with formaldehyde using amide bases at temperatures of from ?40° C. up to the boiling point of the solvent or solvent mixture used.

Abstract: Coating compositions exhibiting improved reproducibility and improved scratch resistance contain an ethylenically unsaturated binder and filler particles functionalized with an ethylenically unsaturated group-containing monoalkoxy silane.

Abstract: Alkoxysilyl-terminated preopolymers prepared by reacting an alkoxysilane with a prepolymer prepared by reacting a di- or polyisocyanate with both a low molecular weight diol or polyol and a high molecular weight polyol, the respective polyol components present within a specific ratio range, and giving rise to an increased content of urethane groups, and an inhomogenous distribution thereof exhibit high tensile strength and elongation, even without the use of fillers.

Abstract: The invention relates to a homoserine transsuccinylase, which exhibits reduced sensitivity towards L-methionine or SAM in comparison with a homoserine transsuccinylase wild-type enzyme, whereby the latter comprises an amino acid sequence containing a TyrGlnXaaThrPro sub-sequence, the Thr of said sub-sequence lying between positions 285 and 310 of the amino acid sequence and position 1 being filled by the starter methionine. The inventive homoserine transsuccinylase is characterized in that in comparison with the wild-type enzyme at least 2 amino acids are modified, said modification taking place in the Thr of the sub-sequence or in the C-terminal.

Abstract: Phosphonate-functional organosilicon compounds in which the phosphonate ester group is linked to silicon by an Si—C—P linkage are prepared rapidly and in high yield by the hydrolysis and polycondensation of phosphonate-functional alkoxysilanes with water.

Abstract: A method for the production of a chiral compound of the formula (I), R1 being identical or different and being H or an organic radical, where a biotransformation composition comprising a compound of the formula (II), an oxidoreductase, a redox cofactor and a cosubstrate are reacted forming the chiral compound of the formula (I) which is subsequently isolated.

Abstract: A process for preparing alkynecarboxylic acids includes the oxidation of an alkyne alcohol with a hypohalite in the presence of a nitroxyl compound at a pH of greater than 7 with continual addition of the alkyne alcohol and of the hypohalite to the reaction mixture.

Abstract: Phosphorous-modified organosilicon compounds containing silicon-bound methoxy groups and a methylene spacer linking silicon to the phosphorous moiety are easily prepared in high yield and exhibit excellent hydrolysis rates. The compounds are useful, inter alia, as stabilizers in anti-freeze compositions, as cohydrolysis reactants in preparation of modified silicone resins, and in coatings.

Abstract: Alkoxysilane-terminated polymers prepared by reacting an isocyanatoalkoxysilane, preferably an isocyanatodialkyalkoxysilane, with an isocyanate-reactive prepolymer, can provide chain extension even when a monoalkoxy-functional silane, while retaining suitable reactivity profiles. The products are useful in sealants, caulks, coatings, and moldings.

Abstract: Alkoxy-crosslinking one-component moisture curing compositions contain a polymer bearing (alkoxy)(methyl)silylalkyl-terminal groups, and specific silanes as described herein. The compositions exhibit improved shelf life and yet retain other desirable characteristics.

Abstract: A process for preparing ?-functionalized thiazolidines or oxazolidines, each of which are oxycarbonyl-functionalized in the 4-position, by adding a base to a reaction mixture comprising an oxycarbonyl-functionalized thiazolidine or oxazolidine and an electrophile at a temperature of greater than ?40° C.

Abstract: Non-proteinogenic L-amino acids produced by direct fermentation of a microorganism strain known per se having a deregulated cysteine metabolism in a manner known per se, which comprises adding, during the fermentation, a nucleophilic compound to the fermentation batch in a manner such that this leads to the production of non-proteinogenic L-amino acids by the microorganism strain.

Abstract: A pyrF gene is useful as a selection marker gene for an expression system for the production of proteins in mushrooms of the genus Trametes, Coriolus or Polyporus. The pyrF gene includes a DNA sequence SEQ ID NO: 1 from position 1133 up to and including position 1877 or DNA-sequence SEQ, ID NO: 2 from position 1 up to and including position 684 or a DNA-sequence with a sequence homology greater than 60% relative to the above-mentioned regions of sequence SEQ ID NO: 1 or SEQ ID NO: 2.