Patents Assigned to Debiotech S.A.
  • Publication number: 20120029937
    Abstract: A dialysis device comprising a prescriber interface and a programming means configured to allow, via the prescriber interface, input of a set of therapeutic objectives and a treatment plan and a re-evaluation means configured to, as a function of the therapeutic objectives and the treatment plan, suggest at least one treatment option comprising a set of settings of a treatment session to achieve said set of therapeutic objectives.
    Type: Application
    Filed: March 24, 2010
    Publication date: February 2, 2012
    Applicant: DEBIOTECH S.A.
    Inventors: Frédéric Neftel, Pascal Bernard, Thomas Hertz
  • Patent number: 8104352
    Abstract: The present invention relates to a pressure measurement unit to determine positive and negative fluid pressure within a disposable for medical devices. As part of the disposable, the invention consists of a rigid measurement chamber, which is covered by an elastic form part. This measurement chamber can be connected to a medical device, which is equipped with a pressure transducer. Specific shapes of the elastic form part and specific instrument interfaces ensure the connection between this elastic form part, the measurement chamber and the pressure transducer to exclude the influence of atmospheric pressure during measurements. The coupling and the sealing ability against atmospheric pressure is controllable. Such pressure measurement units can be used to measure fluid pressure in disposable to control for example fluid pumps.
    Type: Grant
    Filed: January 20, 2007
    Date of Patent: January 31, 2012
    Assignee: Debiotech S.A.
    Inventors: Hans-Gerd Evering, Didier Vecten, Florent Junod
  • Patent number: 7901727
    Abstract: The present invention relates to a process for manufacturing a porous coating with structures in the micro or nano-size domain characterized by the following steps: —providing a support having a surface, —depositing on said surface one mono-layer of temporary particles, —depositing a coating on said temporary particles in such a way that the thickness of said coating is less than the particle diameter, —eliminating said temporary particles and thereby obtaining a porous coating, the pores of said coating corresponding to the spaces previously occupied by the temporary particles and at least a part of the pores communicating with the external environment, —applying a coating fixation step, characterized by the fact that said temporary particles are deposited on said surface in such a way that, after particle deposition, more than 50% of the temporary particles are in contact with a maximum of two adjacent particles and otherwise are separated by an empty space.
    Type: Grant
    Filed: September 15, 2006
    Date of Patent: March 8, 2011
    Assignee: Debiotech S.A.
    Inventors: Heinrich Hofmann, Frederic Neftel, Laurent-Dominique Piveteau
  • Patent number: 7887509
    Abstract: Medical device for the delivery and/or the extraction of fluid to and/or from a patient, said medical device comprising a pumping unit (1) for pumping a fluid, a warming chamber (2) with an inlet (3) and an outlet (4) and containing a heating element (5) for warming said fluid, fluid volume measuring means (13-18) and a fluid line crossing said pumping and warming units (1, 2), characterized by the fact that said heating element (5) is adapted to be fully immersed in the fluid which is crossing said warming chamber (2) and by the fact that said fluid measuring means comprise temperature sensing means adapted to measure the fluid temperature on at least two separate points and electrical parameter measuring means for determining at least one electrical parameter such as current, power or frequency applied to said heating element (5). The invention also includes a method for using this device.
    Type: Grant
    Filed: December 29, 2006
    Date of Patent: February 15, 2011
    Assignee: Debiotech S.A.
    Inventors: Pierre Thiebaud, Didier Vecten, Yvan Favre, Hans-Gerd Evering
  • Publication number: 20100256569
    Abstract: The present invention relates to a medical injection device for delivering medium to a patient comprising at least two microneedles, wherein microneedle tips are arranged with a distance.
    Type: Application
    Filed: October 23, 2008
    Publication date: October 7, 2010
    Applicant: DEBIOTECH S.A.
    Inventors: Astrid Cachemaille, Francois Cannehan
  • Patent number: 7782467
    Abstract: A method of measuring a volume in a fluid flow micromechanical device includes: a) providing and positioning an optical apparatus for measuring the profile of a surface; b) providing a device for acquiring and processing the images coming from the optical apparatus for measuring a profile; c) placing the moving member in a first position and then in a second position, and activating the optical apparatus for measuring the profile of the surface to direct a light beam on the reference face, and activating the image acquisition and processor device to obtain a first image in the first position of the moving member and a second image in the second position; and d) comparing the second image with the first image of the reference face to determine the variation in the volume of the cavity generated by the deformation of the moving member.
    Type: Grant
    Filed: January 24, 2006
    Date of Patent: August 24, 2010
    Assignee: Debiotech S.A.
    Inventor: Eric Chappel
  • Publication number: 20090199917
    Abstract: The invention relates to a microfluidic device comprising a first plate forming the substrate and including at least one perforation and, on either side of said first plate, at several locations, a material for defining passage portions consisting, in at least one of said locations, of an activatable material varying in volume on activation, said material being disposed at said locations in an arrangement that, during a first phase and upon activation of at least one location consisting of said activatable material, transforms it from a first configuration to a second configuration, modifying a three-dimensional network corresponding, in the second configuration and depending on the selected location(s) that are activated in said first phase, to different liquid paths including passage portions in offset planes parallel to the plane of the first plate, at least on either side of said first plate, and between which at least one of said perforations is located.
    Type: Application
    Filed: May 29, 2007
    Publication date: August 13, 2009
    Applicant: DEBIOTECH S.A.
    Inventors: Veronique Vallet, Frederic Neftel, Laurent-Dominique Piveteau, Niklaus Schneeberger
  • Publication number: 20090187139
    Abstract: Peritoneal dialysis system comprising pumping means, therapy data receiving means and processing means, said processing means being designed to process said therapy data and to impart a switching sequence to said pumping means characterized by the fact that said processing means are furthermore designed to impart a specific exchange profile for each exchange cycle.
    Type: Application
    Filed: February 7, 2007
    Publication date: July 23, 2009
    Applicant: DEBIOTECH S.A.
    Inventors: Diego Mastalli, Alfio Quarteroni, Paolo Zunino
  • Publication number: 20090097037
    Abstract: The invention relates to a method of measuring a volume in a fluid flow micromechanical device (100) by optically measuring the profile of a surface therein, the method comprising the following steps: a) providing and positioning an optical apparatus (10; 50; 30; 70) for measuring the profile of a surface; b) providing means (24; 44; 64; 84) for acquiring and processing the images coming from the optical apparatus for measuring a profile; c) placing said moving member (133) in a first position and then in a second position, and activating said optical apparatus for measuring the profile of the surface to direct a light beam on said reference face, and activating the image acquisition and processor means to obtain a first image in said first position of the moving member (133) and a second image in said second position; and d) comparing said second image with said first image of said reference face to determine the variation in the volume of the cavity (138) generated by the deformation of the moving member
    Type: Application
    Filed: January 24, 2006
    Publication date: April 16, 2009
    Applicant: DEBIOTECH S.A.
    Inventor: Eric Chappel
  • Patent number: 7497840
    Abstract: The invention concerns a system and a method of use of said system for performing fluid administration on a patient, the system comprising: a liquid pump (1), a liquid distribution system (2) connected to said pump (1) in such a way that liquid can flow from the liquid distribution system (2) to the pump (1) and vice versa, liquid supply means (3) for supplying liquid to a patient (4) via said liquid distribution system (2) and said pump (1), a patient conduit (5) adapted for connecting said liquid distribution system (2) to a patient (4), the system being characterized by the fact that said liquid pump (1) is unidirectional and that said liquid distribution system (2) comprises switching means designed to alternatively connect the pump enter line (56) with the supply means (3) or with the patient conduit (5).
    Type: Grant
    Filed: August 2, 2004
    Date of Patent: March 3, 2009
    Assignee: Debiotech S.A.
    Inventors: Frederic Neftel, Florent Junod, Didier Vecten
  • Patent number: 7311503
    Abstract: The fluid-flow device (100) of the invention comprises a stack (30) covered by a closure wafer (20), said stack (30) comprising a support wafer (36), a layer of insulating material (34), and a silicon layer (32). The closure wafer (20) and/or said silicon layer (32) are machined so as to define a cavity (38) between said closure wafer (20) and said silicon layer (32), said support wafer (36) has at least one duct (102) passing right through it, said layer of insulating material (34) presenting at least one zone (35) that is entirely free of material placed at least in line with said duct (102) so as to co-operate with said cavity (38) to define a moving member (40) in said silicon layer (32), the moving member being suitable under the pressure of liquid in said cavity (38) for reversibly moving towards said support wafer (36) until contact is made between said moving member (40) and said support wafer (36).
    Type: Grant
    Filed: September 26, 2005
    Date of Patent: December 25, 2007
    Assignee: Debiotech S.A.
    Inventors: Harald T. Van Lintel, Didier Maillefer, Stephan Gamper
  • Publication number: 20040167495
    Abstract: The invention relates to a device for injecting liquid, comprising a piece of tubing on which there is situated at least a first liquid occlusion system. According to the invention, a regulation system (4) is situated upstream from the first occlusion system, the two systems defining an intermediate segment in which the pressure, in the absence of injection, is greater than the pressure that exists downstream from the first occlusion system so as to direct any leak of liquid from the first occlusion system downstream. The invention is applicable to a pump used for injecting contrast liquid for medical imaging.
    Type: Application
    Filed: February 12, 2004
    Publication date: August 26, 2004
    Applicant: DEBIOTECH S.A.
    Inventor: Frederic Neftel
  • Patent number: 6716193
    Abstract: The invention relates to a device for injecting liquid, comprising a piece of tubing on which there is situated at least a first liquid occlusion system. According to the invention, a regulation system (4) is situated upstream from the first occlusion system, the two systems defining an intermediate segment in which the pressure, in the absence of injection, is greater than the pressure that exists downstream from the first occlusion system so as to direct any leak of liquid from the first occlusion system downstream. The invention is applicable to a pump used for injecting contrast liquid for medical imaging.
    Type: Grant
    Filed: June 17, 1999
    Date of Patent: April 6, 2004
    Assignee: Debiotech S.A.
    Inventor: Frédéric Neftel
  • Patent number: 6558343
    Abstract: The present invention relates to the treatment of kidney insufficiency and more particularly to a peritoneal dialysis device. The device is adapted to function in tidal peritoneal dialysis (TPD) mode, the device being characterized by the fact that it is provided with a variation system for varying the parameters of dialysate exchange over time. The system is designed in such a manner as to vary the duration between two cycles for exchanging fractions of dialysate.
    Type: Grant
    Filed: September 29, 2000
    Date of Patent: May 6, 2003
    Assignee: Debiotech S.A.
    Inventor: Frédéric Neftel
  • Patent number: 6364279
    Abstract: The invention relates to a closure device for closing a hose by pinching, and in particular for closing a flexible tube or hose used in the medical field. Essentially, the device comprises a closure piece (62) provided with a circularly arcuate slot (70) which is extended by a circular orifice (76). The closure piece (62) can be rotated about a point O on a circle of radius (R) equal to the radius of the slot (70).
    Type: Grant
    Filed: October 5, 2000
    Date of Patent: April 2, 2002
    Assignee: Debiotech S.A.
    Inventors: Frédéric Neftel, Bernard Bouvier
  • Patent number: 6280430
    Abstract: An assembly comprising a flanged flask and a syringe device fixable thereto is provided. The syringe device includes a guide member for cooperating with the body of the flask. The guide member includes a first end with an internal guide surface at its terminal portion and a fastening mechanism set back from the internal guide surface. The internal guide surface cooperates with the cylindrical body of the flask and the fastening mechanism attached to the flange of the flask. A second end of the guide member provides translational guidance to a syringe.
    Type: Grant
    Filed: May 1, 1997
    Date of Patent: August 28, 2001
    Assignee: Debiotech S.A.
    Inventors: Frédéric Neftel, Bernard Bouvier
  • Patent number: 6120490
    Abstract: The invention relates to a piercing pin (10) for perfusion purposes to pierce the resilient capsule of a bottle and allow liquid to flow from the bottle (44) to a perfusion system. The piercing pin (10) for perfusion purposes is constituted by a pin body (30) having a longitudinal projection (36) including at least one internal duct (37a, 37b), and piercing means (20) including an internal duct (25) extending said internal duct (37a, 37b) of the longitudinal projection (36), said piercing means (20) are removable and are connected to said longitudinal projection (36) by temporary fastening means (28, 38) for transmitting piercing force to said longitudinal projection (36) and for coming apart from said longitudinal projection (36) when the pin is withdrawn from the bottle. The piercing pin can thus be used once only.
    Type: Grant
    Filed: January 9, 1998
    Date of Patent: September 19, 2000
    Assignee: Debiotech S.A.
    Inventor: Frederic Neftel
  • Patent number: 6085574
    Abstract: A device for sensing gas bubbles in a liquid flowing through a duct, particularly the outlet duct of a peristaltic pump, including two piezoelectric components shaped and excited so that they vibrate axially. One of the components is a transmitter and the other is a receiver. One of the piezoelectric components is secured to a movable support, and its displacement is detected in order to detect excess pressure in the liquid flowing through the duct.
    Type: Grant
    Filed: July 3, 1997
    Date of Patent: July 11, 2000
    Assignee: Debiotech S.A.
    Inventors: Frederic Neftel, Bernard Bouvier
  • Patent number: 5968014
    Abstract: The invention relates to injection apparatus that is capable of operating continuously. According to the invention, the apparatus comprises two independent injection bottles (12) of at least one liquid that is to be injected into a patient via a tube, each of the bottles including means (51) for detecting that injection of the liquid contained in the bottle has terminated, which means control means (53) for interrupting the flow of liquid. The apparatus comprises upstream injection apparatus (10) having two feeder tubes (50) connected to respective bottles (12), and downstream injection apparatus (70) with pump means (72, 84) for pumping the liquid and connected firstly to the patient via a downstream tube (78) and secondly to coupling means (54). An application is performing perfusion prior to radiological examination using an X-ray or an NMR scanner.
    Type: Grant
    Filed: February 24, 1998
    Date of Patent: October 19, 1999
    Assignee: DEBIOTECH S.A.
    Inventors: Frederic Neftel, Bernard Bouvier
  • Patent number: 5927885
    Abstract: A buffer reservoir suitable for absorbing surplus ink and a writing instrument including the buffer reservoir are provided. The buffer reservoir includes a mixture of microbeads that are hydrophobic relative to the ink and microbeads that are hydrophilic relative to the ink. The mixture of microbeads may either be uniform throughout the entire volume of the buffer reservoir, or non-uniform throughout the entire volume of the buffer reservoir, with the proportion of hydrophilic microbeads to hydrophobic microbeads being smaller in the zone immediately in contact with the feed tip and larger in the zone farthest away from the feed tip. Preferably, the proportion of hydrophilic microbeads is in the range of about 2% to about 10%, by weight, relative to the total weight of the buffer reservoir. The writing instrument includes a reservoir for liquid ink, a feed tip opening out into the reservoir, and a buffer reservoir.
    Type: Grant
    Filed: April 14, 1997
    Date of Patent: July 27, 1999
    Assignee: Debiotech S.A.
    Inventors: Jose Duez, Vincent Bedhome