Abstract: The present invention relates to a recombinant host cell which is capable of producing a dicarboxylic acid and which comprises a mutant malate dehydrogenase resulting in an increased production of the dicarboxylic acid. The invention also relates to a process for producing a dicarboxylic acid, which method comprises fermenting said recombinant host cell in a suitable fermentation medium and producing the dicarboxylic acid.
Type:
Grant
Filed:
August 21, 2020
Date of Patent:
May 24, 2022
Assignee:
DSM IP ASSETS B.V.
Inventors:
Alrik Pieter Los, Rene Marcel De Jong, Remko Tsjibbe Winter, Ben Den Dulk
Abstract: The present invention provides genetically engineered host organisms capable of producing terpenoids. The present invention also relates terpenoids obtained from such genetically engineered organisms. Examples of the produced terpenoids include carotenoids, ionones, abienol, and other isoprenoid derived compounds. In addition, the invention relates to a methods of for the preparation of terpenoids using such a genetically engineered organism.
Abstract: The present invention relates a heteropolysaccharide characterized in that it is substantially composed of the monosaccharides glucose and galactose and rhamnose and N-acetylgalactosamine and a process for the production thereof. The invention further relates to a bacterium capable of producing said heteropolysaccharide and to the use of the heteropolysaccharide and the bacterium for improving the texture of fermented milk products.
Type:
Grant
Filed:
November 3, 2014
Date of Patent:
May 10, 2022
Assignee:
DSM IP ASSETS B.V.
Inventors:
Cornelia Elizabeth Paulina Maljaars, Pim Van Hee
Abstract: The present invention relates to a yeast cell, in particular a recombinant yeast cell, the cell lacking enzymatic activity needed for the NADH-dependent glycerol synthesis or the cell having a reduced enzymatic activity with respect to the NADH-dependent glycerol synthesis compared to its corresponding wild-type yeast cell, the cell comprising one or more heterologous nucleic acid sequences encoding an NAD+-dependent acetylating acetaldehyde dehydrogenase (EC 1.2.1.10) activity. The invention further relates to the use of a cell according to the invention in the preparation of ethanol.
Type:
Grant
Filed:
February 15, 2021
Date of Patent:
May 10, 2022
Assignee:
DSM IP ASSETS B.V.
Inventors:
Jacobus Thomas Pronk, Antonius Jeroen Adriaan Van Maris, Victor Gabriel Guadalupe Medina
Abstract: The invention relates to a variant of a parent polypeptide which is preferably a hexose transporter, wherein the variant comprises an amino acid sequence which, when aligned with the amino acid sequence of SEQ ID NO: 1, comprises a substitution of amino acids N376 and T89, the positions of said amino acids being defined with reference to the amino acid sequence of SEQ ID NO: 1. Said polypeptide is suitable in the production of ethanol from arabinose-rich biomass such as corn stover and corn starch.
Type:
Grant
Filed:
November 12, 2018
Date of Patent:
May 10, 2022
Assignee:
DSM IP ASSETS B.V.
Inventors:
Antonius Jeroen Adriaan Van Maris, Jacobus Thomas Pronk, Maarten Dirk Verhoeven
Abstract: The present invention relates to topical compositions comprising erythrulose and a caprylate, characterized in that the amount of the caprylate in the composition is 5 higher than the amount of erythrulose.
Type:
Grant
Filed:
June 28, 2018
Date of Patent:
May 10, 2022
Assignee:
DSM IP ASSETS B.V.
Inventors:
Christine Mendrok-Edinger, Sebastien Mongiat, Thomas Rudolph
Abstract: The present invention relates to a yeast cell that is genetically modified comprising: a) a disruption of one or more aldehyde dehydrogenase (E.C:1.2.1.4) native to the yeast; b) one or more nucleotide sequence encoding a heterologous NAD+-dependent acetylating acetaldehyde dehydrogenase (E.C. 1.2.1.10); c) one or more nucleotide sequence encoding a homologous or heterologous acetyl-CoA synthetase (E.C. 6.2.1.1); and d) a modification that leads to reduction of glycerol 3-phosphate phosphohydrolase (E.C. 3.1.3.21) and/or glycerol 3-phosphate dehydrogenase (E.C. 1.1.1.8 or E.C. 1.1.5.3) activity, native to the yeast.
Type:
Grant
Filed:
May 18, 2016
Date of Patent:
May 3, 2022
Assignee:
DSM IP ASSETS B.V.
Inventors:
Paul Klaassen, Jozef Petrus Johannes Schmitz, Paulus Petrus De Waal, Arjen Bouma
Abstract: The present invention concerns a rope health monitoring system and a rope for such rope health monitoring system whereby the rope comprises objects which are remotely detectable, readable and programmable identification (ID) tags and whereby the rope monitoring system comprises said rope, at least one ID tag reader device mounted along said predetermined path of the rope, to detect at least the identity and optionally the historic health status and/or at least one physical rope parameters of the individual rope section provided with and identified by the at least one ID tag, at least one ID tag writing device, to write a new health status of the individual rope section to the at least one ID tag, at least one means to measure at least one rope operation parameter, a computing unit provided with data, whereby the computing unit is equipped with an algorithm capable to compute the relative longitudinal positioning of individual sections of the rope and the additional damage or damages suffered by individual sec
Abstract: The invention relates to an endless shaped article comprising at least one strip of material forming a plurality of convolutions of the strip of material, the strip having a longitudinal axis, wherein each convolution of said strip comprises a twist along the longitudinal axis of said strip, wherein said twist is an odd multiple of 180 degrees. The invention also relates to a method to manufacture said article, and its use as sling, loop, belt or chain link.
Type:
Grant
Filed:
June 11, 2013
Date of Patent:
April 26, 2022
Assignee:
DSM IP ASSETS B.V.
Inventors:
Rigobert Bosman, Dietrich Wienke, Johanna Gertruda Kersjes, Jozef Siegfried Johannes Homminga, Roelof Marissen, Christiaan Henri Peter Dirks
Abstract: The present invention relates to a process for preparing a granular nylon salt material, wherein an aqueous mixture, comprising at least 65 wt. % of salt components, and at most 35 wt. % of an aqueous medium, the weight percentages (wt. %) being relative to the total weight of the aqueous mixture, is flashed from a pressure vessel via a flash valve into a flash chamber, thereby evaporating the aqueous medium in an amount sufficient to result in a residual moisture content of at most 7.5 wt. %, and forming a granular nylon salt material. The invention also relates to a process for preparing a nylon polymer, comprising direct solid state polymerization of the granular salt material prepared by flash granulation.
Type:
Grant
Filed:
January 31, 2020
Date of Patent:
April 19, 2022
Assignee:
DSM IP ASSETS B.V.
Inventors:
Bas Van Laarhoven, Eric Grolman, Michiel Muyris
Abstract: The present invention relates to propanediol monoacetate mononitrate as well as the use thereof as antimicrobial agent, in particular for cosmetic applications.
Type:
Grant
Filed:
December 11, 2018
Date of Patent:
April 19, 2022
Assignee:
DSM IP ASSETS B.V.
Inventors:
Christine Mendrok-Edinger, Peter Riebel, Angela Wildermann
Abstract: The present invention relates to a method for producing a flavour composition comprising providing a slurry of yeast cell walls and contacting the slurry of yeast cell walls with a glucanase and with an endoprotease, followed by separating a liquid fraction by solid/liquid separation to provide the liquid flavour composition.
Type:
Grant
Filed:
September 15, 2016
Date of Patent:
April 12, 2022
Assignee:
DSM IP ASSETS B.V.
Inventors:
Bernadette Theresia Morel, Marco Alexander Van Den Berg
Abstract: A recombinant host capable of producing a steviol glycoside which overexpresses a polypeptide which mediates steviol glycoside transport and which polypeptide comprises the amino acid sequence set forth in SEQ ID NO: 29 or an amino acid sequence having at least about 50% sequence identity thereto. A recombinant host capable of producing a steviol glycoside which has been modified, preferably in its genome, to result in a deficiency in the production of a polypeptide which mediates steviol glycoside transport and which polypeptide comprises the amino acid sequence set forth in SEQ ID NO: 29 or an amino acid sequence having at least about 50% sequence identity thereto.
Type:
Grant
Filed:
August 15, 2016
Date of Patent:
April 12, 2022
Assignee:
DSM IP ASSETS B.V.
Inventors:
Viktor Marius Boer, Priscilla Zwartjens, Eric Van Den Berg
Abstract: Processes for preparing a polyamide, a polyamide material obtained by such processes, a nylon salt to be used therein, and processes for making the nylon salt are disclosed. The processes for preparing the polyamide include a direct solid state polymerization process. The salt used herein is a granulate material, prepared by a process, comprising spraying an aqueous solution comprising a diamine and a dicarboxylic acid dissolved in an aqueous medium, or an aqueous slurry comprising a diammonium dicarboxylate salt dispersed in an aqueous medium directly obtained from such an aqueous solution, onto or in a fluidized bed of diammonium dicarboxylate salt particles, while evaporating the aqueous medium, thereby forming a granulate salt material.
Type:
Grant
Filed:
January 31, 2020
Date of Patent:
April 12, 2022
Assignee:
DSM IP ASSETS B.V.
Inventors:
Bas Van Laarhoven, Christiaan Johannes Cornelis Stoelwinder, Mark Helmsing
Abstract: A recombinant host capable of producing a steviol glycoside which overexpresses a polypeptide which mediates steviol glycoside transport and which polypeptide comprises the amino acid sequence set forth in SEQ ID NO: 35 or SEQ ID NO: 38 or an amino acid sequence having at least about 50% sequence identity to either thereto. A recombinant host capable of producing a steviol glycoside which has been modified, preferably in its genome, to result in a deficiency in the production of a polypeptide which mediates steviol glycoside transport and which polypeptide comprises the amino acid sequence set forth in SEQ ID NO: 35 or SEQ ID NO: 38 or an amino acid sequence having at least about 50% sequence identity to either thereto.
Type:
Grant
Filed:
April 10, 2020
Date of Patent:
April 5, 2022
Assignee:
DSM IP ASSETS B.V.
Inventors:
Viktor Marius Boer, Priscilla Zwartjens, Eric Van Den Berg
Abstract: The present invention is directed to an iron fortified bouillon concentrate comprising fat, sodium chloride, monosodium glutamate, ferric pyrophosphate, and a citrate buffer. It is directed to a process to prepare an iron fortified bouillon concentrate. This bouillon concentrate allows easy iron supplementation at low cost, without affecting either the original taste or the colour of the bouillon after dissolving and cooking, it does not discolour during shelf life of the bouillon concentrate, and it provides an optimal source of bioavailable iron to the consumer of the food comprising said bouillon concentrate.
Abstract: Composite panel comprising at least one layer containing at least one tape comprising a thermoplastic polymer selected from the group consisting of polyolefins, polyesters, polyvinyl alcohols, polyacrylonitriles, polyamides or polyketone, wherein the tape has a tensile strength of at least 1.2 GPa and an areal density of between 5 and 150 g/m2, and an adhesive in contact with said layer, whereby the amount of the adhesive in contact with one side of the at least one layer is between 0.2 and 15 g/m2, wherein the adhesive is a plastomer wherein said plastomer is a random copolymer of ethylene or propylene and one or more C2 to C12 a-olefin co-monomers and wherein said plastomer has a density as measured according to 1801183 of between 860 and 930 kg/m3. In a preferred embodiment the tape comprises an ultra high molecular weight polyethylene. The composite panel is used in a ballistic resistant article.
Type:
Grant
Filed:
March 7, 2013
Date of Patent:
March 22, 2022
Assignee:
DSM IP ASSETS B.V.
Inventors:
David Michael Cummins, Dietrich Wienke, Roelof Marissen, Koen Van Putten, Joke Hendrix