Patents Assigned to DSM IP Assets B.V.
  • Patent number: 11193145
    Abstract: The invention relates to an enzyme composition, a process for the preparation thereof and the use of the enzyme composition in enzymatic hydrolysis.
    Type: Grant
    Filed: March 27, 2019
    Date of Patent: December 7, 2021
    Assignee: DSM IP ASSETS B.V.
    Inventors: Maaike Appeldoorn, Loes Elizabeth Bevers
  • Use
    Patent number: 11191772
    Abstract: The present invention relates to the use of erythrulose as antimicrobial agent as well as to composition comprising said agent.
    Type: Grant
    Filed: June 28, 2018
    Date of Patent: December 7, 2021
    Assignee: DSM IP ASSETS B.V.
    Inventors: Christine Mendrok-Edinger, Sebastien Mongiat, Thomas Rudolph
  • Patent number: 11186850
    Abstract: The present invention describes a recombinant yeast cell functionally expressing one or more heterologous nucleic acid sequences encoding for ribulose-1,5-phosphate carboxylase/oxygenase (EC4.1.1.39; Rubisco), and optionally one or more molecular chaperones for Rubisco, and one or more phosphoribulokinase (EC2.7.1.19; PRK), wherein the phosphoribulokinase is under control of a promoter (the “PRK promoter”) that enables higher expression under anaerobic conditions than under aerobic conditions.
    Type: Grant
    Filed: April 24, 2020
    Date of Patent: November 30, 2021
    Assignee: DSM IP ASSETS B.V.
    Inventors: Ioannis Papapetridis, Antonius Jeroen Adriaan Van Maris, Jacobus Thomas Pronk, Paulus Petrus De Waal, Niels Lauret, Maarten Dirk Verhoeven, Jozef Petrus Johannes Schmitz
  • Patent number: 11181169
    Abstract: A chain is provided which includes a plurality of interconnected chain-links. At least one chain-link of the chain has a braided core which includes a first primary strand having polymeric elongated elements having a tenacity of at least 1.0 N/tex. The braided core is braided from at least 2 consecutive turns of the primary strand. Also disclosed is a braided endless shaped element suitable as chain-link for the chain as well as a chain which has a tenacity (Ten) in N/Tex and a combined titer of the 2 legs of the chain-link having polymeric elongated elements (T) in MTex satisfying the relationship of Ten?0.50*T?0.05.
    Type: Grant
    Filed: March 6, 2017
    Date of Patent: November 23, 2021
    Assignee: DSM IP ASSETS B.V.
    Inventors: Karel Jozef Wetzels, Dietrich Wienke, Jozef Siegfried Johannes Homminga, Roelof Marissen, Rigobert Bosman
  • Patent number: 11178894
    Abstract: A recombinant host capable of producing a steviol glycoside which overexpresses a polypeptide which mediates steviol glycoside transport and which polypeptide comprises the amino acid sequence set forth in SEQ ID NO: 29 or an amino acid sequence having at least about 50% sequence identity thereto. A recombinant host capable of producing a steviol glycoside which has been modified, preferably in its genome, to result in a deficiency in the production of a polypeptide which mediates steviol glycoside transport and which polypeptide comprises the amino acid sequence set forth in SEQ ID NO: 29 or an amino acid sequence having at least about 50% sequence identity thereto.
    Type: Grant
    Filed: August 15, 2016
    Date of Patent: November 23, 2021
    Assignee: DSM IP ASSETS B.V.
    Inventors: Viktor Marius Boer, Priscilla Zwartjens, Eric Van Den Berg
  • Patent number: 11174489
    Abstract: The present invention relates to a yeast cell, in particular a recombinant yeast cell, the cell lacking enzymatic activity needed for the NADH-dependent glycerol synthesis or the cell having a reduced enzymatic activity with respect to the NADH-dependent glycerol synthesis compared to its corresponding wild-type yeast cell, the cell comprising one or more heterologous nucleic acid sequences encoding an NAD+-dependent acetylating acetaldehyde dehydrogenase (EC 1.2.1.10) activity. The invention further relates to the use of a cell according to the invention in the preparation of ethanol.
    Type: Grant
    Filed: February 15, 2021
    Date of Patent: November 16, 2021
    Assignee: DSM IP ASSETS B.V.
    Inventors: Jacobus Thomas Pronk, Antonius Jeroen Adriaan Van Maris, Victor Gabriel Guadalupe Medina
  • Patent number: 11174383
    Abstract: This invention relates to a method for preparing a composition having a melt viscosity of between 160 Pas and 400 Pas, as determined according to ISO-11443-2014 at 270° C. and a shear rate of 265 l/s, and a volume resistivity of at most 105 Ohm·cm, measured according to ASTM D257 on an injection molded test sample of 3 mm thickness and a diameter of 50 mm and coated with a gold layer on an upper and lower surface and, as well as the composition itself and painted parts comprising the composition.
    Type: Grant
    Filed: February 8, 2018
    Date of Patent: November 16, 2021
    Assignee: DSM IP ASSETS B.V.
    Inventors: Ronald Michaël Alexander Maria Schellekens, Michelle Elizabeth Seitz
  • Patent number: 11167270
    Abstract: The present invention is related to a new metal powder catalytic system (catalyst), its production and its use in hydrogenation processes.
    Type: Grant
    Filed: May 1, 2018
    Date of Patent: November 9, 2021
    Assignee: DSM IP ASSETS B.V.
    Inventors: Werner Bonrath, Roman Goy, Jonathan Alan Medlock
  • Patent number: 11167292
    Abstract: Centrifuges are useful to, among other things, remove red blood cells from whole blood and retain platelets and other factors in a reduced volume of plasma. Platelet rich plasma (PRP) and or platelet poor plasma (PPP) can be obtained rapidly and is ready for immediate injection into the host. Embodiments may include valves, operated manually or automatically, to open ports that discharge the excess red blood cells and the excess plasma into separate receivers while retaining the platelets and other factors in the centrifuge chamber. High speeds used allow simple and small embodiments to be used at the patient's side during surgical procedures. The embodiments can also be used for the separation of liquids or slurries in other fields such as, for example, the separation of pigments or lubricants.
    Type: Grant
    Filed: March 30, 2020
    Date of Patent: November 9, 2021
    Assignee: DSM IP Assets B.V.
    Inventors: John E. Nash, William T. Fisher, Douglas G. Evans
  • Patent number: 11168054
    Abstract: Novel biaromatic compounds, which are vitamin D analogs, processes for their preparation and cosmetic, dermatological and pharmaceutical preparations containing one or more of these compounds.
    Type: Grant
    Filed: December 14, 2016
    Date of Patent: November 9, 2021
    Assignee: DSM IP ASSETS B.V.
    Inventors: Igor Bendik, Piero Geotti-Bianchini, Marc Heidl, Eileen Jackson, Alexander Schlifke-Poschalko
  • Patent number: 11160743
    Abstract: The invention relates to an improved process for the manufacture of nano-sized organic UV absorbers having a mean particle size distribution (Dv50) determined by light scattering of less than 200 nm.
    Type: Grant
    Filed: October 9, 2017
    Date of Patent: November 2, 2021
    Assignee: DSM IP ASSETS B.V.
    Inventor: Bernd Schlegel
  • Patent number: 11154076
    Abstract: The present invention is directed to isolated microorganisms as well as strains and mutants thereof, biomasses, microbial oils, compositions, and cultures; methods of producing the microbial oils, biomasses, and mutants; and methods of using the isolated microorganisms, biomasses, and microbial oils.
    Type: Grant
    Filed: February 6, 2018
    Date of Patent: October 26, 2021
    Assignee: DSM IP Assets B.V.
    Inventors: Kirk E. Apt, Paul Warren Behrens, Jon Milton Hansen, Joseph W. Pfeifer, III, Tracey Lynn Stahl, Ross Zirkle
  • Patent number: 11149288
    Abstract: The present invention relates to the field of molecular biology and cell biology. More specifically, the present invention relates to a CRISPR-CAS system for a lipolytic yeast host cell.
    Type: Grant
    Filed: February 3, 2020
    Date of Patent: October 19, 2021
    Assignee: DSM IP ASSETS B.V.
    Inventors: Bernard Meijrink, René Verwaal, Bianca Elisabeth Maria Gielesen, Johannes Andries Roubos
  • Patent number: 11149268
    Abstract: The present invention is based on the advantageous use of single-stranded oligonucleotides in the in vivo (within a cell) assembly of double-stranded oligonucleotides into a single double-stranded nucleic acid construct. The present invention relates to the use of at least a first and a second single-stranded oligonucleotide in the assembly within a cell of at least two double-stranded nucleic acid molecules into a single double-stranded nucleic acid construct of pre-determined sequence, wherein the first and second single-stranded oligonucleotide are essentially complementary to each other.
    Type: Grant
    Filed: December 15, 2016
    Date of Patent: October 19, 2021
    Assignee: DSM IP ASSETS B.V.
    Inventors: Johannes Andries Roubos, René Verwaal, Bianca Elisabeth Maria Gielesen, Brenda Vonk
  • Patent number: 11149293
    Abstract: This invention provides a fermentation method of producing gellan gum, wherein a certain amount of fermentation broth is retained in the fermentor as a seed for next batch fermentation or transferred to another fermentor as a seed for next batch fermentation in that fermentor. The fermentation method of this invention reduces fermentation cost of gellan gum and lowers contamination risk during seed cultivation.
    Type: Grant
    Filed: November 1, 2018
    Date of Patent: October 19, 2021
    Assignees: Zhejiang DSM Zhongken Biotechnology Co. Ltd, DSM IP Assets B.V.
    Inventors: Jie Zhao, Wouter Adrianus Van Winden, Rogier Meulenberg, Zhihui Gao
  • Patent number: 11149122
    Abstract: The invention relates to a method for manufacturing a composite sheet comprising high performance polyethylene fibres and a polymeric resin comprising the steps of assembling HPPE fibres to a sheet, applying an aqueous suspension of a polymeric resin to the HPPE fibres, partially drying the aqueous suspension, optionally applying a temperature and/or a pressure treatment to the composite sheet wherein the polymeric resin is a homopolymer or copolymer of ethylene and/or propylene. The invention further relates to composite sheets obtainable by said method and articles comprising the composite sheet such as helmets, radomes or a tarpaulins.
    Type: Grant
    Filed: October 7, 2016
    Date of Patent: October 19, 2021
    Assignee: DSM IP ASSETS B.V.
    Inventors: Roelof Marissen, Johannes Wilms, Leonard Nielaba
  • Patent number: 11142783
    Abstract: The invention relates to an optimized seed train expansion process.
    Type: Grant
    Filed: June 8, 2017
    Date of Patent: October 12, 2021
    Assignee: DSM IP ASSETS B.V.
    Inventors: Andre De Castro Bizarro Duarte Canelas, Wouter Adrianus Van Winden
  • Patent number: 11136277
    Abstract: The present invention relates to a process for the production of ?-springene of formula (I) wherein a compound of formula (II) is heated in the presence of a catalyst.
    Type: Grant
    Filed: September 13, 2018
    Date of Patent: October 5, 2021
    Assignee: DSM IP ASSETS B.V.
    Inventors: Raphael Beumer, Werner Bonrath, Marc-André Mueller, Bettina Wüestenberg
  • Patent number: 11136600
    Abstract: The present invention relates to a eukaryotic cell that is genetically modified comprising one or more heterologous gene encoding: a) D-glucose-6-phosphate dehydrogenase and/or b) 6-phosphogluconate dehydrogenase; and/or c) glucose dehydrogenase, gluconolactonase and gluconate kinase, wherein a), b) and glucose dehydrogenase in c) are NAD+ dependent.
    Type: Grant
    Filed: October 3, 2016
    Date of Patent: October 5, 2021
    Assignee: DSM IP Assets B.V.
    Inventors: Ioannis Papapetridis, Jacobus Thomas Pronk, Antonius Jeroen Adriaan Van Maris, Paul Klaassen
  • Publication number: 20210304851
    Abstract: A computer-based method for determining a sunscreen composition comprising a plurality of UV filter substances, comprises the steps of selecting at least one constraint for at least one characteristic of the composition to be determined (step 30), the at least one constraint comprising a sunscreen performance target; selecting an optimization objective from a plurality of optimization objectives (step 50); and automatically determining the sunscreen composition as a composition of filter substances from a set of filter substances (step 100), the composition meeting the at least one constraint and being optimized with respect to the selected optimization objective. The automatic determination comprises the steps of generating a plurality of candidate compositions, determining a sunscreen performance of the candidate compositions using a performance simulation tool and comparing the determined sunscreen performance of the candidate compositions with the sunscreen performance target.
    Type: Application
    Filed: March 29, 2021
    Publication date: September 30, 2021
    Applicant: DSM IP Assets B.V.
    Inventor: Alexander SCHLIFKE