Patents Assigned to Endologix, Inc.
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Publication number: 20120016456Abstract: A system for treating an aneurysm comprises an elongate flexible shaft and an expandable member. An expandable scaffold is disposed over the expandable member and may be expanded from a collapsed configuration to an expanded configuration. A double-walled filling structure is disposed over the scaffold and has an outer wall and an inner wall. The filling structure is adapted to be filled with a hardenable fluid filing medium so that the outer wall conforms to an inside surface of the aneurysm and the inner wall forms a substantially tubular lumen to provide a path for blood flow. In the expanded configuration the scaffold engages the inner wall of the filling structure. A tether is releasably coupled with the filling structure and the flexible shaft thereby constraining axial movement of the structures relative to each other.Type: ApplicationFiled: September 23, 2011Publication date: January 19, 2012Applicant: Endologix, Inc.Inventors: Steven L. Herbowy, Michael A. Evans, Anant Kumar, K.T. Venkateswara Rao, Matthew R. Hellewell, Gil Laroya
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Patent number: 8048145Abstract: Aneurysms are treated by filling at least one double-walled filling structure with a curable medium within the aneurysm. The filling structures may be delivered over balloon deployment mechanisms in order to shape and open tubular lumens therethrough. Scaffolds are placed into the tubular lumens in order to help maintain the shape, anchor the filling structures in place, and provide improved blood flow transition into and out of the tubular lumens.Type: GrantFiled: April 28, 2006Date of Patent: November 1, 2011Assignee: Endologix, Inc.Inventors: Michael A. Evans, Gwendolyn A. Watanabe, Amy Lee, Steven L. Herbowy
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Patent number: 8034100Abstract: A graft deployment system, comprises an elongate, flexible catheter body, having a proximal end and a distal end and comprising an outer sheath and an inner core that is axially moveable with respect to the outer sheath. A main vessel graft restraint comprising a first peelable cover for restrains a main vessel portion of a graft. In a bifurcated graft, a first branch vessel graft restraint restrains a first branch vessel portion of the graft. A second branch vessel graft restraint restrains a second branch vessel portion of the graft. The first peelable cover is coupled to a main branch release element and wherein each of the main vessel graft restraint, first branch vessel graft restraint, and the second branch vessel graft restraint are positioned within the catheter body in a graft loaded condition.Type: GrantFiled: November 25, 2003Date of Patent: October 11, 2011Assignee: Endologix, Inc.Inventors: Samuel M. Shaolian, Gilbert Madrid, To Van Pham, Trinh Van Pham
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Publication number: 20110224782Abstract: Disclosed is a bifurcated tubular endoluminal vascular prosthesis, useful in treating, for example, an abdominal aortic aneurysm. The prosthesis comprises a self expandable wire support structure surrounded at least in part by a flexible tubular membrane. A delivery catheter and methods are also disclosed.Type: ApplicationFiled: February 14, 2011Publication date: September 15, 2011Applicant: Endologix, Inc.Inventors: Myles S. Douglas, Gilbert Madrid, Mehrdad M. Shokoohi
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Publication number: 20110224772Abstract: A method for deploying an endoluminal vascular prosthesis using a deployment catheter that has at least a main graft portion and a first branch graft portion. The deployment catheter preferably comprises an elongate, flexible catheter body having a proximal end and a distal end, and an outer sheath and an inner core that is axially moveable with respect to the outer sheath. The catheter preferably comprises a main graft restraint that has a main graft release mechanism comprising a main graft sheath and a suture threaded through a plurality of the openings in the main graft sheath. The catheter further comprises at least one branch graft restraint comprising at least one branch graft release mechanism.Type: ApplicationFiled: March 11, 2011Publication date: September 15, 2011Applicant: ENDOLOGIX, INC.Inventors: Kevin Mayberry, Trinh Pham, Stefan G. Schreck
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Publication number: 20110218617Abstract: Some embodiments of an endoluminal prosthesis comprise a graft having a first end and a second end, a first stent positioned at a first end of the graft, the first stent comprising a plurality of proximal apices and a plurality of distal apices, a second stent positioned axially adjacent to the first stent comprising a plurality of proximal apices positioned at a first end of the second stent. In some embodiments, the first stent can be partially covered by the graft such that the proximal apices of the first stent are not covered by the graft. The distal apices of the first stent can be positioned approximately on a first or a second plane offset from the first plane. The second stent can be positioned relative to the first stent such that the plurality of proximal apices of the second stent are spaced apart from the plurality of distal apices of the first stent. Further, one or more of the proximal apices of the second stent can be positioned approximately on a third or a fourth plane.Type: ApplicationFiled: March 2, 2011Publication date: September 8, 2011Applicant: ENDOLOGIX, INC.Inventors: Jonathon Nguyen, Jacqueline Macias, Elbert Tzeng, Stefan Schreck
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Publication number: 20110054586Abstract: Some embodiments relate to endoluminal prostheses having a first stent portion and a second stent portion, a main graft body comprising first, second, and third portions, the second portion having a cross-sectional size that is significantly larger than a cross-sectional size of the first or third portions, and also significantly larger than a cross-sectional size of the target vessel. In some embodiments, the first portion of the main graft body can be attached to the first stent portion and the third portion of the main graft body can be attached to the second stent portion. The prostheses can be configured such that the second portion of the main graft body is not directly attached to the first stent portion, the second stent portion, or any other internal support structure. In some embodiments, one or more openings can be formed in the second portion of the main graft body.Type: ApplicationFiled: April 28, 2010Publication date: March 3, 2011Applicant: Endologix, Inc.Inventors: Kevin Mayberry, Daniel Clair, Craig Welk, Stefan G. Schreck
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Publication number: 20110054587Abstract: Some embodiments of the present disclosure are directed to a method of deploying a graft in a patient's blood vessel having at least a first and a second branch blood vessel, comprising advancing a delivery catheter into a blood vessel, the delivery catheter supporting a fenestrated prosthesis therein, wherein the prosthesis comprises a main graft body, exposing at least one branch sheath, the branch sheath being positioned within the delivery catheter so as to project from a main lumen of the prosthesis through a first opening formed through a wall of the prosthesis, and advancing an angiographic catheter into the branch sheath and cannulating a first target branch vessel before expanding the main graft body of the prosthesis.Type: ApplicationFiled: April 28, 2010Publication date: March 3, 2011Applicant: Endologix, Inc.Inventors: Kevin Mayberry, Daniel Clair, Craig Welk, Stefan G. Schreck
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Publication number: 20110054594Abstract: Some embodiments of the present disclosure are directed to endoluminal prostheses having one or more reinforced fenestrations therein. The one or more reinforced fenestrations can have improved sealing capabilities with respect to branch grafts deployed within the fenestrations, improved tear resistance and expandability, and improved pull-out resistance for branch grafts. In some embodiments, the endoluminal prosthesis can have a main graft body defining a flow lumen therethrough, a first opening passing through a wall of the main graft body, and a first support member supported by the main graft body and overlapping an edge of the first opening, the first support member being configured to at least increase the tear resistance of the main graft body adjacent to the first opening. The support member can be stitched or otherwise attached to the main graft adjacent to the fenestration.Type: ApplicationFiled: April 28, 2010Publication date: March 3, 2011Applicant: Endologix, Inc.Inventors: Kevin Mayberry, Daniel Clair, Craig Welk, Stefan G. Schreck
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Patent number: 7892277Abstract: Disclosed is a bifurcated tubular endoluminal vascular prosthesis, useful in treating, for example, an abdominal aortic aneurysm. The prosthesis comprises a self expandable wire support structure surrounded at least in part by a flexible tubular membrane. A delivery catheter and methods are also disclosed.Type: GrantFiled: May 3, 2006Date of Patent: February 22, 2011Assignee: Endologix, Inc.Inventors: Myles S. Douglas, Gilbert Madrid, Mehrdad M. Shokoohi
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Publication number: 20110022153Abstract: Some embodiments are directed to a stent graft comprising a first stent graft having a first stent, a first inner graft supported by the first stent, a second inner graft supported by the first stent, and an outer graft. The second inner graft can be spaced apart from the first inner graft along the length of the first stent so that a portion of the first stent is not covered by either the first inner graft or the second inner graft. A first portion and a second portion of the outer graft can be attached to the first stent, the outer graft being unsupported by the stent between the first and second portions so as to form a fillable space between the outer graft, the first inner graft, and the second inner graft. Some embodiments further comprise a second stent graft deployable within the inside of the first stent graft to sealingly cover the uncovered portion of the first stent.Type: ApplicationFiled: July 27, 2010Publication date: January 27, 2011Applicant: Endologix, Inc.Inventors: Stefan Schreck, Daniel Hawkins
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Publication number: 20110015718Abstract: Some embodiments are directed to a deployment system for deploying a stent graft within a passageway, comprising a delivery catheter having an outer sheath, a proximal end, and a distal end, a stent having a first end and a second end, a graft having a first end and a second end, and at least one connecting element extending from the second end of the stent to the first end of the graft so as to connect the stent to the graft. In some embodiments, the stent can be supported within the outer sheath at a first axial position in a collapsed state, and the graft can be supported within the outer sheath at a second axial position different than the first axial position in a collapsed state, such that the stent does not overlap or substantially overlap the graft in the collapsed state within the deployment system.Type: ApplicationFiled: July 15, 2010Publication date: January 20, 2011Applicant: ENDOLOGIX, INC.Inventor: Stefan Schreck
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Publication number: 20100318174Abstract: Disclosed is a tubular endoluminal vascular prosthesis, useful in treating, for example, an abdominal aortic aneurysm. The prosthesis comprises a self-expandable wire support structure having a tubular main body support and first and second branch supports. The prosthesis can have a plurality of radially outwardly extending barbs. The branch supports may articulate with the main body to permit the branches to pivot laterally from the axis of the main body throughout a substantial range of motion.Type: ApplicationFiled: August 20, 2010Publication date: December 16, 2010Applicant: ENDOLOGIX, INC.Inventors: Samuel M. Shaolian, Frank M. Zeng
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Publication number: 20100318181Abstract: Disclosed is a tubular endoluminal vascular prosthesis, useful in treating, for example, an abdominal aortic aneurysm. The prosthesis comprises a self-expandable wire support structure having a tubular main body support and first and second branch supports. The prosthesis can have a plurality of radially outwardly extending barbs. The branch supports may articulate with the main body to permit the branches to pivot laterally from the axis of the main body throughout a substantial range of motion.Type: ApplicationFiled: August 20, 2010Publication date: December 16, 2010Applicant: ENDOLOGIX, INC.Inventors: Samuel M. Shaolian, Frank M. Zeng
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Publication number: 20100280588Abstract: Some embodiments of the present disclosure are directed to methods and systems for percutaneously treating dissections in a patient's vasculature, such as, without limitation, the aorta. The method can include deploying a catheter containing a collapsed anchoring element, frame, and cover through a first vessel to an entry point of the dissection. In some embodiments, the anchoring element can be secured to the second branch vessel. The frame can be expanded in the first branch vessel. The cover can be unfolded over at least a portion of the entry point. The cover then reduces blood flow into the entry point.Type: ApplicationFiled: April 30, 2010Publication date: November 4, 2010Applicant: ENDOLOGIX, INC.Inventor: Stefan G. Schreck
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Publication number: 20100261662Abstract: The present disclosure is directed to methods and systems for stabilizing an extracellular matrix in a wall of a blood vessel. The method comprises delivering a therapeutic agent into mural thrombus, which covers the wall of the blood vessel. The agent is transported from the mural thrombus into the extracellular matrix of the vessel wall by diffusion. The agent then acts to reduce the enzymatic degradation of protein in the extracellular matrix.Type: ApplicationFiled: April 9, 2010Publication date: October 14, 2010Applicant: ENDOLOGIX, INC.Inventors: Stefan G. Schreck, Charles S. Bankert, Kemal Schankereli
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Publication number: 20100179638Abstract: The present invention relates to the endoluminal repair of abdominal aortic aneurysms at the aortic and iliac bifurcation. In particular, a deployment system and graft are disclosed for deploying the bifurcated graft within both iliac branches, as well as the aortic trunk, from a single vascular access.Type: ApplicationFiled: March 25, 2010Publication date: July 15, 2010Applicant: ENDOLOGIX, INC.Inventors: Samuel M. Shaolian, Gilbert Madrid, To Van Pham, Trinh Van Pham, Thanh Van Nguyen
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Patent number: 7691135Abstract: The present invention relates to the endoluminal repair of abdominal aortic aneurysms at the aortic and iliac bifurcation. In particular, a deployment system and graft are disclosed for deploying the bifurcated graft within both iliac branches, as well as the aortic trunk, from a single vascular access.Type: GrantFiled: October 21, 2003Date of Patent: April 6, 2010Assignee: ENDOLOGIX, Inc.Inventors: Samuel M. Shaolian, Gilbert Madrid, To Van Pham, Trinh Van Pham, Thanh Van Nguyen
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Publication number: 20100004730Abstract: Some embodiments are directed to a catheter system comprising an introducer having a main body, an introducer sheath projecting from the main body, and a first seal supported within the introducer and a catheter having a main body, an outer sheath projecting from the main body, a second seal supported within the catheter, and an inner core configured to be advanced axially through the main body, the second seal, and the outer sheath. The introducer can be configured to be selectively engageable with the catheter so that the catheter can be selectively and removably linked with the introducer in the axial direction. The catheter system can also be configured such that, when the introducer and the catheter are linked, the catheter can be rotatable relative to the introducer. The introducer can be configured to radially restrain an endoluminal prosthesis.Type: ApplicationFiled: July 1, 2009Publication date: January 7, 2010Applicant: ENDOLOGIX, INC.Inventors: Joshua Benjamin, Stefan Schreck
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Publication number: 20090216315Abstract: An endoluminal prosthesis system deployable in a region of a patient's vasculature having one or more branch vessels, having a first main graft body having at least a first and second opening therein and a second main graft body having at least a first and a second opening therein. The first openings can be smaller than the second openings. The second main graft body can be expandable substantially within the first main graft body such that the second openings of each graft body do not substantially cover the first openings of the other graft body. The resulting graft system can have two openings therein, each being defined by the first openings in each of the first and second main graft bodies. One or more branch grafts can be attached to cover the openings in the main graft bodies, and the main graft bodies can have one or more cutouts therein.Type: ApplicationFiled: February 20, 2009Publication date: August 27, 2009Applicant: ENDOLOGIX, INC.Inventors: Stefan G. Schreck, Joshua Benjamin, Kevin Mayberry