Patents Assigned to Endologix, Inc.
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Publication number: 20090155337Abstract: A method for stabilizing an extra cellular matrix layer in the vascular system of the body is disclosed herein. The method can comprise placing a vascular catheter adjacent to the extra cellular matrix layer, delivering a solution containing a bioflavonoid to the extra cellular matrix layer with the vascular catheter, and cross-linking protein in the extra cellular matrix layer. The bioflavonoid can be a catechin, particularly epigallocatechin gallate (EGCG).Type: ApplicationFiled: November 12, 2008Publication date: June 18, 2009Applicant: ENDOLOGIX, INC.Inventors: Stefan G. Schreck, Kemal Schankereli
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Publication number: 20090105806Abstract: A tubular prosthesis can be formed by rolling a sheet of material about a longitudinal axis, thereby forming a plurality of annular rings that can be arranged so as to be longitudinally adjacent one another, thus forming a tubular prosthesis. Each annular member can expand and contract independent of the other annular members. A graft material can extend between the plurality of annular members.Type: ApplicationFiled: October 23, 2008Publication date: April 23, 2009Applicant: ENDOLOGIX, INCInventors: Joshua Benjamin, Stefan Schreck
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Patent number: 7520895Abstract: Disclosed is a bifurcated tubular endoluminal vascular prosthesis, useful in treating, for example, an abdominal aortic aneurysm. The prosthesis comprises a self expandable wire support structure surrounded at least in part by a flexible tubular membrane. A delivery catheter and methods are also disclosed.Type: GrantFiled: April 8, 2002Date of Patent: April 21, 2009Assignee: Endologix, Inc.Inventors: Myles S. Douglas, Gilbert Madrid, Mehrdad M. Shokoohi
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Publication number: 20070299497Abstract: Disclosed is a tubular endoluminal vascular prosthesis, useful in treating, for example, an abdominal aortic aneurysm. The prosthesis comprises a self-expandable wire support structure having a tubular main body support and first and second branch supports. The support structure may include one or more sliding links to permit axial movement while maintaining patency of the central lumen. The branch supports may articulate with the main body to permit the branches to pivot laterally from the axis of the main body throughout a substantial range of motion.Type: ApplicationFiled: June 18, 2007Publication date: December 27, 2007Applicant: ENDOLOGIX, INC.Inventors: Samuel Shaolian, Frank Zeng
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Publication number: 20070112412Abstract: Disclosed is a tubular endoluminal vascular prosthesis, useful in treating, for example, an abdominal aortic aneurysm. The prosthesis comprises a self expandable wire support structure surrounded by a flexible tubular membrane. A delivery catheter and methods are also disclosed.Type: ApplicationFiled: January 16, 2007Publication date: May 17, 2007Applicant: ENDOLOGIX, INC.Inventors: Mehrdad Shokoohi, Michael Henson, Gerad von Hoffmann
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Patent number: 6953475Abstract: Disclosed is a deployment catheter for deploying a tubular endoluminal vascular prosthesis, useful in treating, for example, an abdominal aortic aneurysm. The deployment catheter includes a proximal tubular section and a distal tubular section which are axially movable in opposite directions to deploy a prosthesis. A central core extends throughout the proximal tubular section and into the distal tubular section. A reinforcing structure is carried by the central core, spanning the junction between the proximal tubular section and distal tubular section, to improve flexibility characteristics of the catheter. In one embodiment, the proximal tubular section and/or distal tubular section are rotationally linked to the central core.Type: GrantFiled: September 30, 2003Date of Patent: October 11, 2005Assignee: Endologix, Inc.Inventors: Samuel M. Shaolian, Gilbert Madrid, Thanh Van Nguyen, Trinh Van Pham
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Patent number: 6951572Abstract: A structurally supported bifurcated vascular graft is described having a hollow cylindrical body graft with a top end and bottom end and two hollow cylindrical limb grafts which are attached to the hollow cylindrical body graft near the top end of the body graft. One or more structural supports or stents are attached to either the interior or exterior of the body graft and limb grafts. Further, an apparatus and method for delivering a one-piece bifurcated vascular graft is also described which includes first and second hollow limb tubes for containing the limbs of a bifurcated graft, a third hollow body tube for containing the body of a graft, and a hollow delivery tube capable of encompassing the limb tubes and graft body tube.Type: GrantFiled: August 12, 2003Date of Patent: October 4, 2005Assignee: Endologix, Inc.Inventor: Myles S. Douglas
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Patent number: 6733523Abstract: Disclosed is a tubular endoluminal vascular prosthesis, useful in treating, for example, an abdominal aortic aneurysm. The prosthesis comprises a self-expandable wire support structure having a tubular main body support and first and second branch supports. The support structure may include sliding links to permit flexibility while maintaining patency of the central lumen. The branch supports may articulate with the main body to permit the branches to pivot laterally from the axis of the main body throughout a substantial range of motion. Exoskeleton components or barbs may be provided to resist migration and endoleaks.Type: GrantFiled: June 26, 2001Date of Patent: May 11, 2004Assignee: Endologix, Inc.Inventors: Samuel M. Shaolian, Frank M. Zeng
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Patent number: 6699170Abstract: Disclosed is a balloon catheter having an inflatable balloon having a radiation carrier such as a radiation delivery layer thereon. In one embodiment, the radiation delivery layer comprises one or more layers of metal foil, such as gold. The foil is irradiated, and the balloon is thereafter positioned at a treatment site in a vessel and expanded to bring the metal foil layer into close proximity with the vessel wall. In another embodiment, the radiation carrier is in the form of a dopant in the balloon material. Methods of using the balloon include radiation dosing a site following a balloon dilatation or other procedure, and simultaneously performing balloon angioplasty and radiation dosing.Type: GrantFiled: October 16, 2000Date of Patent: March 2, 2004Assignee: Endologix, Inc.Inventors: Michael Crocker, George F. Kick, Mark A. Siminuk
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Patent number: 6689157Abstract: Disclosed is a dual lumen access catheter, for facilitating placement of two procedure wires across a treatment site. In one application, the catheter is used to place a first wire extending between a contralateral iliac and an ipsilateral iliac across the terminal bifurcation of the aorta, and a second wire extending through a portion of the ipsilateral iliac and into the aorta. Methods of placing the wires, such as for subsequent deployment of an abdominal aortic aneurysm bifurcation graft, are also disclosed.Type: GrantFiled: December 21, 2001Date of Patent: February 10, 2004Assignee: Endologix, Inc.Inventors: Gilbert Madrid, Myles Douglas, Samuel M. Shaolian
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Patent number: 6685618Abstract: Disclosed is a thin film radiation source, which may be used to deliver a radioactive dose to a site in a body lumen. The source comprises a thin flexible substrate, and a layer of radioisotope attached thereto. The source may further comprise additional layers such as one or more tie layers disposed between the substrate and the radioisotope layer and one or more outer coating layers. In one embodiment, the source is wrapped around an inflatable balloon. Inflation of the balloon at a treatment site positions the source directly adjacent to the vessel wall, and allows irradiation of the site following or simultaneously with a balloon angioplasty, stent implantation, or stent sizing procedure.Type: GrantFiled: August 31, 2001Date of Patent: February 3, 2004Assignee: Endologix, Inc.Inventors: Lisa A. Tam, Brett A. Trauthen
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Patent number: 6663665Abstract: The present invention relates to the endoluminal repair of abdominal aortic aneurysms at the aortic and iliac bifurcation. In particular, a deployment system and graft are disclosed for deploying the bifurcated graft within both iliac branches, as well as the aortic trunk, from a single vascular access.Type: GrantFiled: February 28, 2001Date of Patent: December 16, 2003Assignee: Endologix, Inc.Inventors: Samuel M. Shaolian, Gilbert Madrid, To Van Pham, Trinh Van Pham, Thanh Van Nguyen
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Patent number: 6660030Abstract: Disclosed is a deployment catheter for deploying a tubular endoluminal vascular prosthesis, useful in treating, for example, an abdominal aortic aneurysm. The deployment catheter includes a proximal tubular section and a distal tubular section which are axially movable in opposite directions to deploy a prosthesis. A central core extends throughout the proximal tubular section and into the distal tubular section. A reinforcing structure is carried by the central core, spanning the junction between the proximal tubular section and distal tubular section, to improve flexibility characteristics of the catheter. In one embodiment, the proximal tubular section and/or distal tubular section are rotationally linked to the central core.Type: GrantFiled: December 22, 2000Date of Patent: December 9, 2003Assignee: Endologix, Inc.Inventors: Samuel M. Shaolian, Gilbert Madrid, Thanh Van Nguyen, Trinh Van Pham
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Patent number: 6508835Abstract: Disclosed is a tubular endoluminal vascular prosthesis, useful in treating, for example, an abdominal aortic aneurysm. The prosthesis comprises a self expandable wire support structure surrounded by a flexible tubular membrane. A delivery catheter and methods are also disclosed.Type: GrantFiled: November 28, 2000Date of Patent: January 21, 2003Assignee: Endologix, Inc.Inventors: Samuel M. Shaolian, M. Frank Zeng
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Patent number: 6500202Abstract: A deployment catheter for deploying a tubular endoluminal vascular prosthesis includes a proximal tubular section and a distal tubular section which are axially movable in opposite directions to deploy the prosthesis. A central core extends throughout the proximal tubular section and into the distal tubular section. In one embodiment, a reinforcing structure is carried by the central core, spanning the junction between the proximal tubular section and distal tubular section. In another embodiment, the proximal tubular section and/or distal tubular section are rotationally linked to the central-core.Type: GrantFiled: March 15, 2000Date of Patent: December 31, 2002Assignee: Endologix, Inc.Inventors: Samuel M. Shaolian, Gilbert Madrid, Thanh Van Nguyen, Trinh Van Pham
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Patent number: 6491619Abstract: Disclosed are sources and methods for delivering a radioactive dose to a site in a body lumen. The sources are preferably mounted on a balloon or other expandable or deployable mechanical structure. The source and methods enable delivery of a clinically significant dose of radiation into a vessel wall in a relatively short time while using a relatively low activity. The sources also enable delivery of a substantially uniform dose into the vessel wall, whether or not such delivery is through the wall of a stent.Type: GrantFiled: August 25, 2000Date of Patent: December 10, 2002Assignee: Endologix, IncInventors: Brett Trauthen, Lisa Tam, Robert Fazio, Michael Crocker, Edward F. Smith, Gary Strathern
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Patent number: 6440161Abstract: Disclosed is a dual lumen access catheter, for facilitating placement of two procedure wires across a treatment site. In one application, the catheter is used to place a first wire extending between a contralateral iliac and an ipsilateral iliac across the terminal bifurcation of the aorta, and a second wire extending through a portion of the ipsilateral iliac and into the aorta. Methods of placing the wires, such as for subsequent deployment of an abdominal aortic aneurysm bifurcation graft, are also disclosed.Type: GrantFiled: July 7, 1999Date of Patent: August 27, 2002Assignee: Endologix, Inc.Inventors: Gilbert Madrid, Myles Douglas, Samuel M. Shaolian
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Patent number: 6331190Abstract: Disclosed is a tubular endoluminal vascular prosthesis, useful in treating, for example, an abdominal aortic aneurysm. The prosthesis comprises a self expandable wire support structure surrounded by a flexible tubular membrane. A delivery catheter and methods are also disclosed.Type: GrantFiled: January 14, 2000Date of Patent: December 18, 2001Assignee: Endologix, Inc.Inventors: Mehrdad M. Shokoohi, Michael R. Henson, Gerard von Hoffmann
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Patent number: 6261316Abstract: An endoluminal repair of abdominal aortic aneurysms at the aortic and iliac bifurcation. In particular, a deployment system and graft are disclosed for deploying the bifurcated graft within both iliac branches, as well as the aortic trunk, from a single vascular access. The disclosed deployment system includes a delivery catheter having a releasable restraint for the main body section of the graft and separate releasable restraints for each of the first and second branch sections of the graft.Type: GrantFiled: March 11, 1999Date of Patent: July 17, 2001Assignee: Endologix, Inc.Inventors: Samuel M. Shaolian, Gilbert Madrid, To Van Pham, Trinh Van Pham, Thanh Van Nguyen
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Publication number: 20010007954Abstract: The present invention relates to the endoluminal repair of abdominal aortic aneurysms at the aortic and iliac bifurcation. In particular, a deployment system and graft are disclosed for deploying the bifurcated graft within both iliac branches, as well as the aortic trunk, from a single vascular access.Type: ApplicationFiled: February 28, 2001Publication date: July 12, 2001Applicant: ENDOLOGIX, INC.Inventors: Samuel M. Shaolian, Gilbert Madrid, To Van Pham, Trinh Van Pham, Thanh Van Nguyen