Abstract: Methods are disclosed for reprogramming a somatic cell, including an adherent cell and a cell in suspension, into an induced pluripotent stem comprising expressing exogenous Sox-2, exogenous Klf-4, exogenous Oct3/4 from DNA that has not integrated into the genome of the somatic cell, suppressing p53 activity within the somatic cell, and exposing the somatic cell to reprogramming-assistance factors comprising an exogenous Alk-5 inhibitor, an exogenous histone deacetylase inhibitor, and an exogenous activator of glycolysis. Compositions and kits for use in such methods are also disclosed as are cells made by such a method.

Abstract: Methods are disclosed for reprogramming a somatic cell, including an adherent cell and a cell in suspension, into an induced pluripotent stem comprising expressing exogenous Sox-2, exogenous Klf-4, exogenous Oct3/4 from DNA that has not integrated into the genome of the somatic cell, suppressing p53 activity within the somatic cell, and exposing the somatic cell to reprogramming-assistance factors comprising an exogenous Alk-5 inhibitor, an exogenous histone deacetylase inhibitor, and an exogenous activator of glycolysis. Compositions and kits for use in such methods are also disclosed as are cells made by such a method.

Abstract: The present disclosure provides a method for transforming an arsenic sulfide slag and curing and stabilizing the resulting compound by means of microencapsulation, comprising the following steps: (1) preparing arsenic trioxide from the arsenic sulfide slag as a raw material; (2) preparing 4-hydroxy-3-nitrophenylarsonic acid from the arsenic trioxide as a raw material; (3) preparing an iron-manganese dinuclear cluster metal arsenate compound having a porous structure; (4) subjecting the iron-manganese dinuclear cluster metal arsenate compound having a porous structure to surface coating with silicon; (5) synthesizing an Fe(0)/Al-SBA-15 mesoporous composite stabilizer by a hydrothermal reaction; and (6) subjecting the silicon coated iron-manganese dinuclear cluster metal arsenate compound to curing and stabilizing treatment by means of microencapsulation.

Abstract: A vanity mirror assembly for a vehicle sun visor includes a cover assembly configured to be slideably supported within a frame and to cover a reflective element while in a closed position and to at least partially expose the reflective element to a vehicle interior while in an open position. The cover assembly includes a substantially rigid body portion, one or more flexible arms extending from the substantially rigid body, and a biasing member configured to drive the one or more flexible arms away from the substantially rigid body and into a corresponding groove of the frame.

Abstract: A lighting assembly for a vehicle interior includes an electrically conductive connector configured to couple to a circuit board and to electrically couple to a light-emitting diode (LED). The electrically conductive connector is configured to interface with a fuse bulb connector of a fuse bulb mount to couple the lighting assembly to the fuse bulb mount and to electrically couple the LED to the fuse bulb connector, and the electrically conductive connector comprises an interface configured to couple an electrical conductor, separate from the fuse bulb connector, to the electrically conductive connector.

Abstract: Methods are disclosed for reprogramming a somatic cell, including an adherent cell and a cell in suspension, into an induced pluripotent stem comprising expressing exogenous Sox-2, exogenous Klf-4, exogenous Oct3/4 from DNA that has not integrated into the genome of the somatic cell, suppressing p53 activity within the somatic cell, and exposing the somatic cell to reprogramming-assistance factors comprising an exogenous Alk-5 inhibitor, an exogenous histone deacetylase inhibitor, and an exogenous activator of glycolysis. Compositions and kits for use in such methods are also disclosed as are cells made by such a method.

Abstract: A slide-on-rod assembly includes a tube and a carriage configured to move within the tube. The carriage has a first contact surface, the carriage includes a wing rotatably coupled to a body of the carriage, the wing has a second contact surface, the first contact surface of the carriage is configured to contact a corresponding first contact surface of the tube, and the second contact surface of the wing is configured to contact a corresponding second contact surface of the tube. The slide-on-rod assembly also includes a biasing member coupled to the at least one wing and to the body of the carriage. The biasing member is configured to drive the first contact surface of the carriage into contact with the corresponding first contact surface of the tube and the second contact surface of the wing into contact with the corresponding second contact surface of the tube.

Abstract: A vanity mirror assembly for a vehicle sun visor includes a cover assembly configured to be slideably supported within a frame and to cover a reflective element while in a closed position and to at least partially expose the reflective element to a vehicle interior while in an open position. The cover assembly includes a substantially rigid body portion, one or more flexible arms extending from the substantially rigid body, and a biasing member configured to drive the one or more flexible arms away from the substantially rigid body and into a corresponding groove of the frame.

Abstract: A method and an apparatus using aqueous fixatives for fogging of ventilation ductwork, enclosures, or buildings containing dust, lint, and particulates that may be contaminated by radionuclides and other dangerous or unsafe particulate contaminants, which method and apparatus are capable of (1) obtaining full coverage within the ductwork and (2) penetrating and fixing the lint, dust and large particles present in the ductwork so that no airborne particles are released during or after the application of the fixative. New aqueous fogging solutions outperform conventional glycerin-based solutions. These aqueous solutions will fog using conventional methods of application and contain a surfactant to aid wetting and penetration of the lint and dust, a binder to stabilize loose or respirable particles, and an agent to aid in fogging and enhance adhesiveness. The solutions are safe and easy to use.

Abstract: An annular co-extrusion die for extruding multi-layer tubular plastic film has inner die mandrels stacked one upon another. Each die mandrel has a generally U-shaped cross-section with side walls extending substantially in parallel with the longitudinal axis of the die. The outer surfaces of the die side walls each have a series of helical shaped grooves formed therein. An annular outer die member surrounds the first inner die mandrel and the inner surface of the outer member and the outer surface of the first inner die mandrel form a longitudinally extending annular extrusion passage. Additional longitudinally extending annular extrusion passages are formed between outer and inner surfaces of nesting inner die mandrels.

Abstract: A composition comprising a synthetic growth factor analog comprising a non-growth factor heparin binding region, a linker and a sequence that binds specifically to a cell surface receptor and an osteoconductive material where the synthetic growth factor analog is attached to and can be released from the osteoconductive material and is an amplifier/co-activator of osteoinduction.

Abstract: Packaging containing a PVDC barrier layer is manufactured without any significant orientation, with the result that the PVDC harrier layer remains flexible at significantly greater thicknesses than when it is oriented. This increased thickness compensates for the reduced barrier properties resulting from less crystallinity of the PVDC, and hence multilayer plastic tubing can be manufactured in which PVDC is used as a barrier layer instead of aluminum.

Abstract: Stretch film is treated by passing a web of tackifier-containing, unbloomed thin polymer film through a heater so that the web is heated to a temperature sufficient to cause tackifier bloom prior to the web reaching a next stage in an in-line process. Also, a pattern can be applied to a thin polymer film. An oriented web of thin polymer film is passed across at least one heated roller having the pattern engraved thereon to define face regions and relief regions collectively conforming to the pattern. As the web contacts each roller surface, portions of the web positioned over the relief regions receive less heat than portions of the web positioned over the face regions, thereby causing the respective portions of the web to undergo differential, heat-induced shrinkage which imparts the pattern to the thin polymer film.

Abstract: Bags are formed from reclaimed plastic material. Each bag comprises two opposed sheet sections formed substantially entirely of a first polymer class, but also containing impurity particles of a different polymer class. The sheet sections comprise at least two distinct independent layers, with each layer in each sheet section being surface bonded to each adjacent layer in that sheet section. Although discontinuities in each layer resulting from the impurity particles create weak areas and in some cases apertures, the weakened portions of each layer are reinforced by portions of the other layer that are not weakened, since there is a minute likelihood that an impurity particle in one layer will be precisely co-located with an impurity particle in an adjacent layer. Thus, each layer reinforces the other layer to maintain structural integrity of the sheet section and of the bag. Methods for forming such bags are also described.

Abstract: The invention provides synthetic heparin-binding growth factor analogs having two peptide chains each branched from a branch moiety, such as trifunctional amino acid residues, the branch moieties separated by a first linker of from 3 to about 20 backbone atoms, which peptide chains bind a heparin-binding growth factor receptor and are covalently bound to a non-signaling peptide that includes a heparin-binding domain, preferably by a second linker, which may be a hydrophobic second linker. The synthetic heparin-binding growth factor analogs are useful as pharmaceutical agents, soluble biologics or as surface coatings for medical devices.

Abstract: A method of producing a multilayer plastic film from resin starting material includes irradiating a batch of plastic resin material and using irradiated resin from the batch to produce at least one layer of a multilayer plastic film.

Abstract: The present invention discloses a structure of package comprising: a substrate with a die receiving through hole, a connecting through hole structure and a first contact pad; a die disposed within the die receiving through hole; a surrounding material formed under the die and filled in the gap between the die and sidewall of the die receiving though hole; a dielectric layer formed on the die and the substrate; a re-distribution layer (RDL) formed on the dielectric layer and coupled to the first contact pad; a protection layer formed over the RDL; and a second contact pad formed at the lower surface of the substrate and under the connecting through hole structure.

Abstract: A structure of a semiconductor device package having a substrate with a die receiving through hole, a connecting through hole structure and a contact pad. A die is disposed within the die receiving through hole. A surrounding material is formed under the die and filled in the gap between the die and the sidewall of the die receiving though hole. Dielectric layers are formed on the both side surface of the die and the substrate. Re-distribution layers (RDL) are formed on the dielectric layers and coupled to the contact pads. Protection layers are formed over the RDLs.

Abstract: The invention provides synthetic heparin-binding growth factor analogs having two peptide chains each branched from a branch moiety, such as trifunctional amino acid residues, the branch moieties separated by a first linker of from 3 to about 20 backbone atoms, which peptide chains bind a heparin-binding growth factor receptor and are covalently bound to a non-signaling peptide that includes a heparin-binding domain, preferably by a second linker, which may be a hydrophobic second linker. The synthetic heparin-binding growth factor analogs are useful as pharmaceutical agents, soluble biologics or as surface coatings for medical devices.

Abstract: Stretch film is treated by passing a web of tackifier-containing, unbloomed thin polymer film through a heater so that the web is heated to a temperature sufficient to cause tackifier bloom prior to the web reaching a next stage in an in-line process. Also, a pattern can be applied to a thin polymer film. An oriented web of thin polymer film is passed across at least one heated roller having the pattern engraved thereon to define face regions and relief regions collectively conforming to the pattern. As the web contacts each roller surface, portions of the web positioned over the relief regions receive less heat than portions of the web positioned over the face regions, thereby causing the respective portions of the web to undergo differential, heat-induced shrinkage which imparts the pattern to the thin polymer film.