Patents Assigned to Fudan University
  • Patent number: 10980468
    Abstract: Disclosed is a vertigo diagnosis and treatment system including a frame, a revolution device, a rotation device and a seat, the frame comprising a primary frame and a secondary frame arranged oppositely. The revolution device includes a power mechanism and a slewing frame. The slewing frame is arranged between the primary frame and the secondary frame. The primary frame and the secondary frame provide slewing support for the slewing frame. The rotation device includes a power mechanism and a seat rotating frame. The vertigo diagnosis and treatment system further includes a seat biasing mechanism. Under the combined action of the revolution device and the rotation device, the vertigo diagnosis and treatment system according to the present invention can realize three-dimensional free rotation and hovering in any position, thus achieving vertigo diagnosis and treatment.
    Type: Grant
    Filed: February 20, 2020
    Date of Patent: April 20, 2021
    Assignees: EYE & ENT HOSPITAL OF FUDAN UNIVERSITY, SHENZHEN SECOND PEOPLE'S HOSPITAL, SHANGHAI ZEHNIT MEDICAL TECHNOLOGY CO., LTD.
    Inventors: Huawei Li, Guohui Nie, Yinhong Qu
  • Patent number: 10976800
    Abstract: An electronic device includes a processor, a volatile memory, and a non-volatile memory. The non-volatile memory stores a first operating system, and the electronic device works in a first working mode and a second working mode. When the electronic device is in the first working mode, a second operating system is run in the volatile memory. When the processor detects that the electronic device reaches a preset condition for entering the second working mode, the non-volatile memory is enabled, and non-system data in the volatile memory is moved to the non-volatile memory. The non-system data does not include the second operating system. After the movement of the non-system data is completed, the volatile memory is disabled, and the first operating system is run in the non-volatile memory, so that the electronic device enters the second working mode.
    Type: Grant
    Filed: January 29, 2018
    Date of Patent: April 13, 2021
    Assignees: Huawei Technologies Co., Ltd., Fudan University
    Inventors: RenHua Yang, Junfeng Zhao, Wei Yang, Shihai Xiao, Yinyin Lin, Yi Wei
  • Patent number: 10975188
    Abstract: The present invention relates to a rapid assembled small-sized block polymer material with low quenching temperature and the preparation and application thereof. In particular, the present invention discloses a block copolymer, and glass transition temperature of the block copolymer is less than 120° C. The present invention also discloses the preparation and application of the block copolymer. The block copolymer can achieve excellent phase separation and rapid patterning at a lower annealing temperature (e.g. 80° C.) and a shorter annealing time (e.g. 30 s), and a photolithographic pattern with a very high resolution (e.g. 5 nm half-pitch) can be further obtained by etching, which provides a new photolithographic mean for further extension of Moore's Law to achieve semiconductor photolithography with a resolution of less than 10 nm, or even 5 nm (half-pitch).
    Type: Grant
    Filed: June 5, 2017
    Date of Patent: April 13, 2021
    Assignee: FUDAN UNIVERSITY
    Inventors: Hai Deng, Xuemiao Li, Jie Li
  • Patent number: 10971204
    Abstract: Disclosed is a three-dimensional non-volatile ferroelectric memory including a ferroelectric memory array structure, wherein the ferroelectric memory array structure includes multiple layers of ferroelectric memory cell array disposed in a stacked way, and each layer of the ferroelectric memory cell array includes ferroelectric memory cells arranged in rows and columns; wherein word lines and bit lines which are substantially orthogonal to each other are oppositely disposed on two sides of the corresponding ferroelectric memory cell respectively, and a reference ferroelectric body is disposed adjacent to the corresponding ferroelectric memory cell. A polarization direction of an electric domain in the ferroelectric memory cell is not perpendicular to an electric field direction of a write voltage signal applied to the word line and the bit line; and when the write voltage signal is applied between the word line and the bit line.
    Type: Grant
    Filed: December 10, 2018
    Date of Patent: April 6, 2021
    Assignee: FUDAN UNIVERSITY
    Inventors: Anquan Jiang, Xiaojie Chai, Yan Zhang
  • Patent number: 10961515
    Abstract: Disclosed herein are a carbonyl reductase variant and its use in the preparation of (R)-4-chloro-3-hydroxybutyrate. The carbonyl reductase variant is obtained by mutating phenylalanine-85 in an amino acid sequence as shown in SEQ ID NO:4 to methionine. An amino acid or amino acids at one or more positions other than position 85 in the amino acid sequence of the carbonyl reductase may be further replaced. The application also provides a recombinant expression vector carrying the gene encoding the carbonyl reductase variant, a genetically-engineered bacterium carrying the carbonyl reductase variant gene and glucose dehydrogenase gene, and an application of this bacterium in the asymmetric reduction of 4-chloroacetoacetate to prepare (R)-4-chloro-3-hydroxybutyrate.
    Type: Grant
    Filed: June 17, 2020
    Date of Patent: March 30, 2021
    Assignee: Fudan University
    Inventors: Fener Chen, Zedu Huang, Zexu Wang, Minjie Liu
  • Patent number: 10927009
    Abstract: Provided are a method for directly preparing expanded graphite or graphene under normal temperature and normal pressure, a graphene material, and a product. The method comprises the following specific steps: firstly dispersing graphite in an acidic medium containing an oxidizing agent, and then enabling obtained suspension liquid to stand under normal temperature and normal pressure, thus obtaining expanded graphite. The method does not involve any high-temperature high-pressure reaction process, is safe in operation, low in energy consumption and high in efficiency, and is environmentally-friendly. Obtained expanded graphite can realize 50-1500 times of volume expansion, and an sp2 hybridization structure of a graphene sheet layer is basically not damaged; and the obtained expanded graphite can be widely applied to the fields of energy storage, heat management, photoelectronic devices, solar cells, anti-corrosive materials, various composite materials, and the like.
    Type: Grant
    Filed: November 17, 2016
    Date of Patent: February 23, 2021
    Assignee: FUDAN UNIVERSITY
    Inventors: Hongbin Lu, Jiajia Zhang, Yufei Chen
  • Patent number: 10885707
    Abstract: A network for generating 3D shape includes a perceptual network and a Graphic Convolutional Network (GCN). The GCN includes a coarse shape generation network for generating a coarse shape, and a Multi-View Deformation Network (MDN) for refining the coarse shape. The MDN further comprises at least one MDN unit, which in turn comprises a deformation hypothesis sampling module, a cross-view perceptual feature pooling module and a deformation reasoning module. Systems and methods are also provided.
    Type: Grant
    Filed: May 23, 2020
    Date of Patent: January 5, 2021
    Assignee: FUDAN UNIVERSITY
    Inventors: Yanwei Fu, Chao Wen, Yinda Zhang, Zhuwen Li
  • Patent number: 10859293
    Abstract: The present disclosure relates to the technical field of cryogenic cooling. In particular, the present disclosure relates to a mechanical vibration-isolated, liquid helium consumption-free cryogenic cooling device. The system according to some embodiments of the present disclosure comprises: a closed-cycle cryogenic cooling system, a helium heat exchange gas cooling and vibration isolation interface system, a cryogenic throttle valve cooling system, and a temperature feedback control system. The closed-cycle cooling system includes a cold head, a compressor, and a helium pipeline. The cryogenic throttle valve cooling system is thermally coupled to a low-temperature end of the cooling and vibration isolation interface.
    Type: Grant
    Filed: November 29, 2016
    Date of Patent: December 8, 2020
    Assignee: FUDAN UNIVERSITY
    Inventors: Shiwei Wu, Shengyu Zhou, Shuai Zhang, Di Huang, Lifeng Yin, Chunlei Gao, Jian Shen
  • Patent number: 10851050
    Abstract: The present disclosure discloses a biaryl urea ROR?t inhibitor, and specifically relates to a biaryl urea derivative, as represented by formula I, with an ROR?t inhibiting activity, and a preparation process thereof, and a pharmaceutical composition comprising the compound. Further disclosed is use of the compound for treating an ROR?t-related disease.
    Type: Grant
    Filed: April 16, 2020
    Date of Patent: December 1, 2020
    Assignee: FUDAN UNIVERSITY
    Inventors: Yonghui Wang, Yafei Huang, Fazhi Yu, Ting Tang
  • Patent number: 10844017
    Abstract: The present invention belongs to the technical field of chemical pharmaceuticals, and relates to a compound represented by general formula (I) or formula (II) and a preparation method thereof. The compounds are biaryl derivatives with ROR?t activation activity. The biaryl derivatives disclosed in this invention can effectively activate the ROR?t protein receptor, and thereby promote the differentiation of Th17 cells and increasing the production of IL-17, which can be used as an immune modulator for the treatment of various cancers or viral infection-related diseases.
    Type: Grant
    Filed: February 9, 2018
    Date of Patent: November 24, 2020
    Assignee: FUDAN UNIVERSITY
    Inventors: Yonghui Wang, Yafei Huang, Ruomeng Qiu, Ting Tang
  • Patent number: 10839223
    Abstract: A system for activity localization in videos is described, comprising a visual concept detection module, which produces a plurality of first visual concept vectors each representing a probability of containing visual concepts for one of a plurality of sampled frames sampled from an input video; wherein each of the plurality of first visual concept vectors dot-product with a second visual concept vector extracted from a given query sentence, resulting a visual-semantic correlation score; a semantic activity proposal generation module, which generates semantic activity proposals by temporally grouping frames with a high visual-semantic correlation score; and a proposal evaluation and refinement module, which takes the semantic activity proposals, the visual concept vectors and the query sentence as input, and outputs alignment scores and refined boundaries for the proposals. The disclosure also relates to methods thereof.
    Type: Grant
    Filed: November 14, 2019
    Date of Patent: November 17, 2020
    Assignee: FUDAN UNIVERSITY
    Inventors: Yugang Jiang, Shaoxiang Chen
  • Patent number: 10838119
    Abstract: The present disclosure relates to an retroreflective structural colour film and a preparation method thereof. The main steps are as follows: (1) assembling colloidal microspheres to form a monolayer of microspheres; and (2) transferring the monolayer of microspheres onto a transparent substrate which has an adhesive layer to make the monolayer of microspheres partially embedded in the adhesive layer to prepare the retroreflective structural colour film. The retroreflective material has the advantages of the simple preparation process, high reflective brightness and uniformity of reflection colour. Moreover, the retroreflective material can exhibit unique retroreflective structural colour under the illumination of a white light source.
    Type: Grant
    Filed: October 30, 2018
    Date of Patent: November 17, 2020
    Assignee: Fudan University
    Inventors: Li-Min Wu, Jing Zeng, Wen Fan, Qiao-Qiang Gan, Deng-Xin Ji, Hao-Min Song
  • Patent number: 10828359
    Abstract: Provided in the present application are a recombinant sendai virus vector vaccine expressing immunodominant antigens of Mycobacterium tuberculosis, and can be used as therapeutic and preventive antituberculosis vaccine.
    Type: Grant
    Filed: April 19, 2016
    Date of Patent: November 10, 2020
    Assignees: Shanghai Public Health Clinical Center, Fudan University, ID Pharma Co., Ltd.
    Inventors: Xiao-Yong Fan, Tsugumine Shu, Zhi-Dong Hu, Douglas B. Lowrie
  • Patent number: 10783401
    Abstract: A method for generating black-box adversarial attacks on video recognition models is provided, comprising a) passing input video frames into a public image model, to obtain pixel-wise tentative perturbations; b) partitioning the tentative perturbations into tentative perturbation patches; c) estimating the rectification weight required for each patch, via querying the target video model; d) applying the patch-wise rectification weight on the patches, to obtain the rectified pixel-wise perturbations; e) applying one step projected gradient descent (PGD) perturbation on the input video, according to the rectified pixel-wise perturbations; and f) iteratively performing steps a)-e) until an attack succeeds or a query limit is reached. Systems and networks therefor are also provided.
    Type: Grant
    Filed: February 23, 2020
    Date of Patent: September 22, 2020
    Assignee: FUDAN UNIVERSITY
    Inventors: Yugang Jiang, Linxi Jiang, Xingjun Ma
  • Patent number: 10783709
    Abstract: This invention is related to a network for generating 3D shape, including an image feature network, an initial ellipsoid mesh, and a cascaded mesh deformation network. The image feature network is a Visual Geometry Group Net (VGGN) containing five successive convolutional layer groups, and four pooling layers sandwiched by the five convolutional layer groups; and the cascaded mesh deformation network is a graph-based convolution network (GCN) containing three successive deformation blocks, and two graph unpooling layers sandwiched by the three successive deformation blocks. This invention is also related to a system and a method thereof.
    Type: Grant
    Filed: November 12, 2019
    Date of Patent: September 22, 2020
    Assignee: FUDAN UNIVERSITY
    Inventors: Yugang Jiang, Yanwei Fu, Nanyang Wang, Yinda Zhang, Zhuwen Li
  • Patent number: 10777003
    Abstract: This invention is related to a network for generating 3D shape, including an image feature network, an initial ellipsoid mesh, and a cascaded mesh deformation network. The image feature network is a Visual Geometry Group Net (VGGN) containing five successive convolutional layer groups, and four pooling layers sandwiched by the five convolutional layer groups; and the cascaded mesh deformation network is a graph-based convolution network (GCN) containing three successive deformation blocks, and two graph unpooling layers sandwiched by the three successive deformation blocks. This invention is also related to a system and a method thereof.
    Type: Grant
    Filed: July 23, 2019
    Date of Patent: September 15, 2020
    Assignee: FUDAN UNIVERSITY
    Inventors: Yugang Jiang, Yanwei Fu, Nanyang Wang, Yinda Zhang, Zhuwen Li
  • Patent number: 10699129
    Abstract: For video captioning, with an encoding module and a decoding module, the encoding module comprises a plurality of encoding units each receiving a set of video frames, wherein the sets of video frames received by two neighboring encoding units are in chronological order; and the encoding units each producing a spatially attended feature, so that the plurality of encoding units produce a spatially attended feature sequence; and the decoding module comprises a decoding unit chronologically receiving a temporally attended feature obtained from the spatially attended features sequence. Also disclosed is a method thereof.
    Type: Grant
    Filed: November 15, 2019
    Date of Patent: June 30, 2020
    Assignee: FUDAN UNIVERSITY
    Inventors: Yugang Jiang, Shaoxiang Chen
  • Patent number: 10676537
    Abstract: The present invention provides a tissue factor (TF) monoclonal antibody and a preparation method therefor. The monoclonal antibody provided by the present invention can specifically bind with a TF antigen, has high affinity and low immunogenicity, and has the activity of resisting tumors and the like.
    Type: Grant
    Filed: February 20, 2017
    Date of Patent: June 9, 2020
    Assignees: Fudan University, Shanghai Miracogen Inc.
    Inventors: Ke Yu, Xuesai Zhang, Qing Lin, Qingrou Li
  • Patent number: 10662145
    Abstract: The invention relates to the chemical synthesis of pharmaceutical API, and specifically to a method of synthesizing diclofenac sodium, which is a kind of nonsteroidal anti-inflammatory drug for relieving pain.
    Type: Grant
    Filed: February 27, 2019
    Date of Patent: May 26, 2020
    Assignee: FUDAN UNIVERSITY
    Inventors: Fener Chen, Lingdong Wang, Ge Meng, Zedu Huang, Dang Cheng, Haihui Peng, Guanfeng Liang
  • Patent number: 10647665
    Abstract: The present invention discloses a biaryl urea ROR?t inhibitor, and specifically relates to a biaryl urea derivative, as represented by formula I, with an ROR?t inhibiting activity, and a preparation process thereof, and a pharmaceutical composition comprising the compound. Further disclosed is use of the compound for treating an ROR?t-related disease.
    Type: Grant
    Filed: June 19, 2017
    Date of Patent: May 12, 2020
    Assignee: Fudan University
    Inventors: Yonghui Wang, Yafei Huang, Fazhi Yu, Ting Tang