Abstract: An optical measurement system includes a wearable device including a support assembly configured to be worn on a body of a user and a wearable assembly supported by the support assembly. The wearable assembly includes a plurality of light sources configured to emit a plurality of light pulses toward a target within the body of the user and a plurality of detectors each configured to receive a set of photons included in a light pulse included in the plurality of light pulses after the set of photons is scattered by the target. A position of the wearable assembly on the support assembly is adjustable.

Abstract: An illustrative system includes a brain interface system configured to be worn by a user and to output brain activity data representative of brain activity of the user while the user concurrently plays an electronic game and a computing device configured to obtain the brain activity data and modify, based on the brain activity data, an attribute of the electronic game.

Abstract: An exemplary system includes a photodetector configured to generate a plurality of photodetector output pulses over time as a plurality of light pulses are applied to and scattered by a target, a TPSF generation circuit configured to generate, based on the photodetector output pulses, a TPSF representative of a light pulse response of the target, and a control circuit configured to direct the TPSF generation circuit to selectively operate in different resolution modes.

Abstract: An active shield magnetometry system comprises at least one magnetic field actuator configured for generating an actuated magnetic field that at least partially cancels an outside magnetic field, thereby yielding a total residual magnetic field. The active shield magnetometry system further comprises a plurality of magnetometers respectively configured for measuring the total residual magnetic field and outputting a plurality of total residual magnetic field measurements. The active shield magnetometry system further comprises at least one feedback control loop comprising at least one optimal linear controller configured for controlling the actuated magnetic field at least partially based on at least one of the plurality of total residual magnetic field measurements respectively output by at least one of the plurality of magnetometers.

Abstract: A magnetic field measurement system includes a magnetometer having at least one vapor cell, at least one light source to direct at least two light beams through the vapor cell(s), and at least one detector; at least one magnetic field generator to modify an external magnetic field experienced by the vapor cell(s); and at least one processor configured for: applying a first modulation pattern, bmod(t), to the magnetic field generator(s) to modulate a magnetic field at the vapor cell(s), where bmod(t)=[cx cos(?t)+sx sin(?t), cy cos(?t)+sy sin(?t), cz cos(?t)+sz sin(?t)], where cx, sx, cy, sy, cz, and sz are amplitudes and ? is a frequency; directing the light source(s) to direct the light beams through the vapor cell(s); receiving signals from the detector(s); and determining three orthogonal components of the external magnetic field using the received signals. Multi-frequency modulation patterns can alternatively be used.

Abstract: A mental impairment detection system and non-invasive method of detecting mental impairment of a user are provided. A test (e.g., an inhibitory reflex test or a sustained attention test) is administered to the user, brain activity in a frontal lobe of the user is non-invasively detected while the test is administered to the user, and a level of mental impairment of the user is determined based on the brain activity detected in the frontal lobe of the user.

Abstract: A system for training a neurome that emulates a brain of a user comprises a non-invasive brain interface assembly configured for detecting neural activity of the user in response to analog instances of a plurality of stimuli peripherally input into the brain of the user from at least one source of content, memory configured for storing a neurome configured for outputting a plurality of determined brain states of an avatar in response to inputs of the digital instances of the plurality of stimuli, and a neurome training processor configured for determining a plurality of brain states of the user based on the detected neural activity of the user, and modifying the neurome based on the plurality of determined brain states of the user and the plurality of determined brain states of the avatar.

Abstract: An exemplary system includes a PLL circuit and a precision timing circuit connected to the PLL circuit. The PLL circuit has a PLL feedback period defined by a reference clock and includes a voltage controlled oscillator configured to lock to the reference clock and having a plurality of stages configured to output a plurality of fine phase signals each having a different phase, and a feedback divider configured to be clocked by a single fine phase signal included in the plurality of fine phase signals and have a plurality of feedback divider states during the PLL feedback period. The precision timing circuit is configured to generate a timing pulse and set, based on a first combination of one of the fine phase signals and one of the feedback divider states, a temporal position of the timing pulse within the PLL feedback period.

Abstract: The source light having a range of optical wavelengths is split into sample light and reference light. The sample light is delivered into a sample, such that the sample light is scattered by the sample, resulting in signal light that exits the sample. The signal light and the reference light are combined into an interference light pattern having optical modes having oscillation frequency components respectively corresponding to optical pathlengths extending through the sample. Different sets of the optical modes of the interference light pattern are respectively detected, and high-bandwidth analog signals representative of the optical modes of the interference light pattern are output. The high-bandwidth analog signals are parallel processed, and mid-bandwidth digital signals are output. The mid-bandwidth digital signals are processed over an i number of iterations, and a plurality of low-bandwidth digital signals are output on the ith iteration.

Abstract: An optical source sweeps a source light over an optical wavelength range. An interferometer splits the source light into sample light and reference light, delivers the sample light into an anatomical structure, such that the sample light is scattered by the anatomical structure, resulting in physiological-encoded signal light that exits the anatomical structure, and combines the signal light and the reference light into an interference light pattern having an array of spatial components and a plurality of oscillation frequency components. An optical detector array detects intensity values of the array of spatial components.

Abstract: An illustrative system includes a brain interface system configured to be worn by a user and to output brain measurement data representative of brain activity of the user while the user is engaged in an electronic messaging session provided by an electronic messaging platform and a computing device configured to obtain the brain measurement data, determine, based on the brain measurement data, a graphical emotion symbol representative of a mental state of the user while the user is engaged in the electronic messaging session, and provide the graphical emotion symbol for use during the electronic messaging session.

Abstract: An exemplary wearable brain interface system includes a head-mountable component and a control system. The head-mountable component includes an array of photodetectors that includes a photodetector comprising a single-photon avalanche diode (SPAD) and a fast-gating circuit configured to arm and disarm the SPAD. The control system is for controlling a current drawn by the array of photodetectors.

Abstract: An exemplary magnetic field measurement system includes a wearable sensor unit that includes a magnetometer and a twisted pair cable interface assembly electrically connected to the magnetometer.

Abstract: An illustrative research support computing system maintains subject data representative of attributes for research subjects included in a potential subject pool for potential research studies. The system receives, from a client device, an input dataset representative of: 1) a set of parameters defining a research study to be conducted with respect to a research subject group, and 2) a set of criteria for research subjects that are to be included in the research subject group. The system designates a research subject included in the potential subject pool for inclusion in the research subject group based on the set of criteria, and receives research data detected for the research subject in accordance with the set of parameters. The system also provides an output dataset generated based on the research data detected for the research subject in accordance with the set of parameters. Corresponding methods and systems are also disclosed.

Abstract: A magnetic field measurement system includes a wearable device having a plurality of wearable sensor units. Each wearable sensor unit includes a plurality of magnetometers and a magnetic field generator configured to generate a compensation magnetic field configured to actively shield the plurality magnetometers from ambient background magnetic fields. A strength of a fringe magnetic field generated by the magnetic field generator of each of the wearable sensor units is less than a predetermined value at the plurality of magnetometers of each wearable sensor unit included in the plurality of wearable sensor units.

Abstract: A non-invasive optical measurement system comprises a two-dimensional array of photonic integrated circuits (PICs) mechanically coupled to each other. Each PIC is configured for emitting sample light into an anatomical structure, such that the sample light is scattered by the anatomical structure, resulting in physiological-encoded signal light that exits the anatomical structure. Each PIC is further configured for detecting the signal light. The non-invasive optical measurement system further comprises processing circuitry configured for analyzing the detected signal light from each of the PICs, and based on this analysis, determining an occurrence and a three-dimensional spatial location of the physiological event in the anatomical structure.

Abstract: A magnetic field measurement system includes at least one magnetometer having a vapor cell, a light source to direct light through the vapor cell, and a detector to receive light directed through the vapor cell; at least one magnetic field generator disposed adjacent the vapor cell; and a feedback circuit coupled to the at least one magnetic field generator and the detector of the at least one magnetometer. The feedback circuit includes a first feedback loop that includes a first low pass filter with a first cutoff frequency and a second feedback loop that includes a second low pass filter with a second cutoff frequency. The first and second feedback loops are configured to compensate for magnetic field variations having a frequency lower than the first or second cutoff frequency, respectively.

Abstract: A method of making an array of vapor cells for an array of magnetometers includes providing a plurality of separate vapor cell elements, each vapor cell element including at least one vapor cell; arranging the vapor cell elements in an alignment jig to produce a selected arrangement of the vapor cells; attaching at least one alignment-maintaining film onto the vapor cell elements in the alignment jig; transferring the vapor cells elements and the at least one alignment-maintaining film from the alignment jig to a mold; injecting a bonding material into the mold and between the vapor cell elements to bond the vapor cell elements in the selected arrangement; removing the at least one alignment maintaining film from the vapor cell elements; and removing the bonded vapor cells elements in the selected arrangement from the mold to provide the array of vapor.

Abstract: An array of optically pumped magnetometers includes an array of vapor cells; and an array of beam splitters. The array of beam splitters is arranged into columns, including a first column, and rows. Each row and each column includes at least two of the beam splitters. The array of beam splitters is configured to receive light into the first column of the array and to distribute that light from the first column into each of the rows and to distribute the light from each of the rows into a plurality of individual light beams directed toward the vapor cells.

Abstract: An illustrative optical measurement device includes a light source configured to emit light pulses directed at a target. The optical measurement device further includes a detector configured to detect arrival times for photons of the light pulses after the photons are scattered by the target. The optical measurement device further includes a processing unit configured to generate, based on the arrival times of the photons at the detector, histogram data associated with the target. The processing unit is further configured to determine, based on the histogram data, an absolute optical property associated with the target. The processing unit is further configured to determine, based on the absolute optical property, a blood oxygenation level of the user, and perform an operation based on the blood oxygenation level.