Abstract: Disclosed here is a generally applicable framework that utilizes massively-parallel single-cell RNA-seq to compare cell types/states found in vivo to those of in vitro models. Furthermore, Applicants leverage identified discrepancies to improve model fidelity. Applicants uncover fundamental gene expression differences in lineage-defining genes between in vivo systems and in vitro systems. Using this information, molecular interventions are identified for rationally improving the physiological fidelity of the in vitro system. Applicants demonstrated functional (antimicrobial activity, niche support) improvements in Paneth cell physiology using the methods.

Abstract: In accordance with one aspect of the present disclosure, there is provided an apparatus for detecting rain using a wire mesh sensor including: a wire mesh which is configured to include a plurality of transmitters and a plurality of receivers; and a fixing part for fixing the wire mesh; wherein the plurality of transmitters supply electricity to the wire mesh, and wherein, in response to rain being positioned between a specific transmitter among the plurality of transmitters and a specific receiver among the plurality of receivers, the specific receiver is configured to receive the electricity from the specific transmitter and then transmit the electricity to a measuring part, to thereby allow the measuring part to measure conductivity. This hemispherical apparatus can detect rain accurately by making the incident angles of the rain to be vertical regardless of the directions of the rain.

Abstract: An identification method and an unmanned aerial vehicle (UAV) detection apparatus are provided. The identification method, as a method for preventing a collision that may occur in a process of detecting and identifying a plurality of UAVs flying in the air, detects a plurality of UAVs in the air and determines a legitimacy of flight of each of the plurality of UAVs using an identification information request message.

Abstract: Provided is an apparatus and method for predicting the remaining lifetime of an environment data collection sensor in a livestock house. The method for predicting the remaining lifetime of an environment data collection sensor in a livestock house includes (a) collecting livestock house environment information, (b) detecting an error of a sensor from the collected livestock house environment information, (c) generating a dataset for learning, (d) generating a sensor lifetime prediction model to performing learning, and (e) predicting a lifetime of the sensor using a result of the learning.

Abstract: Disclosed herein a disaggregation computing system. The disaggregation computing system comprising: a local computing device that comprises a local processor, a local memory bus, a local memory and a local disaggregation controller; a remote computing device that comprises a remote processor, a remote memory bus, a remote memory and a remote disaggregation controller; and a disaggregation network that connects the local computing device and the remote computing device, wherein the local disaggregation controller and the remote disaggregation controller are configured to: check a response delay for access of the remote memory, and control the access of the remote memory based on the response delay.

Abstract: The present invention relates to genomic informatics and gene-expression profiling. Gene-expression profiles provide complex molecular fingerprints regarding the relative state of a cell or tissue. Similarities in gene-expression profiles between organic states provide molecular taxonomies, classification, and diagnostics. Similarities in gene-expression profiles resulting from various external perturbations reveal functional similarities between these perturbagens, of value in pathway and mechanism-of-action elucidation. Similarities in gene-expression profiles between organic and induced states may identify clinically-effective therapies. Systems and methods herein provide for the measurement of relative gene abundances, including unbiased selection of and construction of probes and targets designed and methods for using known properties of sparsity of measurements to reach gene abundances.

Abstract: The present invention is a system guiding an evacuation route for occupants using an augmented reality of mobile devices. The system includes: an occupant's mobile device installed with an evacuation guidance application for showing an evacuation route from a current location of the occupant to an evacuation point in the occurrence of a disaster; and a server providing a plurality of evacuation route information to the mobile device, wherein the mobile device executes the evacuation guidance application to display an evacuation guidance interface, displays a captured landscape image on an image display area of the evacuation guidance interface, displays one of the plurality of evacuation routes set based on specific information related to the type of disaster, the user's exercise ability, and personal conditions on a map display area of the evacuation guidance interface.

Abstract: Provided are a method and apparatus for evaluating the control logic of an exoskeleton, wherein the method includes acquiring, by a human modeling module, characteristic data of a human model, acquiring, by a device modeling module, characteristic data of an exoskeleton, verifying, by a controllability determination module, a controllability that represents whether control is performable on a target body motion based on the characteristic data of the human model and the characteristic data of the exoskeleton, performing, by a simulation module, the target body motion based on a result verification of the controllability and acquiring simulation data generated during performance of the target body motion, and analyzing, by a performance evaluation module, the simulation data.

Abstract: The present invention provides peptides, salts thereof, peptide conjugates, and salts thereof having an anxiolytic-like effect, for example a peptide comprising any amino acid sequence selected from (i) an amino acid sequence SYLPPLTT (SEQ ID NO: 1), (ii) an amino acid sequence YHIEPV (SEQ ID NO: 2), (iii) an amino acid sequence YLLVK (SEQ ID NO: 3), (iv) an amino acid sequence SYLPPLT (SEQ ID NO: 4), (v) an amino acid sequence FLLVK (SEQ ID) NO. 5), and (vi) an amino acid sequence WLLVK (SEQ ID NO: 6).

Abstract: A method, system, and computer product for determining intracranial pressure (ICP) of a subject non-invasively. The method including: applying at least one selected controlled force to an eye of the subject; imaging retinal vascular pulsation of the eye of the subject over at least one cardiac cycle at the at least one selected controlled force; processing the retinal vascular pulsation images to produce retinal vascular pulsation amplitude data as a time-varying signal; decomposing the time-varying signal into at least two frequency components representing the time-varying signal; determining intracranial pressure from a data basis which includes at least information associated with the frequency components, and wherein the retinal vascular pulsation data includes at least retinal arterial pulsation data.

Abstract: A hydride ion conductor represented by a general formula: Ba2-x-mAxMg1-y-nByH6-x-y-2m-2n??(1), wherein A and B are each selected from at least one or more of the group consisting of Li, Na, K, Rb, and Cs, and 0?x?1, 0?y?1, 0?m?0.2, and 0?n?0.2, excluding a case where x=y=m=n=0.

Abstract: FRET-based analytes detection and related methods and systems are described where a pair of FRET labeled primers and/or oligonucleotides are used that are specific for target sequences located at a distance up to four time the Forster distance of the FRET chromophores presented on the FRET labeled primers and/or oligonucleotides one with respect to the other in one or more polynucleotide analyte; in particular the pair of FRET labeled primers and/or oligonucleotides is combined with a sample and subjected to one or more polynucleotide amplification reactions before measuring FRET signals from at least one FRET chromophore.

Abstract: The present invention relates to a method for reducing localized fat deposits in a subject in need thereof in need thereof by topically treating the subject with rare-earth element doped calcium carbonate particles in combination with low-intensity ultrasound. The rare-earth element doped calcium carbonate particles have good biocompatibility and can increase reactive oxygen species (ROS) production and produce carbon dioxide (CO2) and calcium ions (Ca2+) in the region of administration under the ultrasonic irradiation. The method of the present invention is effective in inducing adipocyte necrosis, inhibiting adipogenesis, and decreasing body weight and useful for body sculpture.

Abstract: A composition for inhibiting intestinal permeability, treating leaky gut related diseases and/or preventing leaky gut related diseases including a Chinese herbal compound material or a Chinese herbal compound extract is provided. The Chinese herbal compound material includes Ganoderma, red jujube, longan and lotus seed. Moreover, the Chinese herbal compound extract includes a Ganoderma extract, a red jujube extract, a longan extract and a lotus seed extract.

Abstract: Systems and methods for optical nanostructures that use the interference of high order Mie resonances to locally control wavefront with high quality factor in two dimensions are described. The high-order Mie-resonant metasurfaces can be used to create band-stop filters, beam deflectors, lenses, beam splitters and holograms with high quality factor.

Abstract: Compositions configured to interact with organic molecules, and related articles and methods, are generally described.

Abstract: Firearm discharge location systems and methods are described. According to one aspect, a firearm discharge location system includes a plurality of microphones spaced from one another, timing circuitry configured to generate a plurality of asynchronous timing references, wherein data capture operations with respect to the microphones of a first pair are synchronized with one another using a first of the timing references and data capture operations with respect to the microphones of a second pair are synchronized with one another using a second of the timing references, and processing circuitry configured to use outputs of the first and second pairs of the microphones to identify a location of a firearm discharge.

Abstract: Disclosed herein is an inspection robot system for the customs inspection of container-loaded cargo. The inspection robot system includes: an attachment-type mobile robot configured to drive in the state of being attached to the top surface of a container; and a flexible robot system configured to interface with the attachment-type mobile robot, to selectively accommodate and extend a flexible robot having multiple degrees of freedom, and to perform inspection on cargo.

Abstract: This disclosure relates to a glasses-type augmented reality apparatus, and system with compact dimensions. An aspect of the present embodiment provides an augmented reality apparatus which provides a wearer with a digital holographic image incident from the outside as a holographic image, the apparatus including a plurality of holographic optical elements (HOEs) arranged in the form of concentric circles having different radii inside an optical configuration worn by the wearer to diffract the incident digital holographic image and provide the diffracted digital holographic image to the wearer.

Abstract: The present invention relates to the technical field of composite materials, and in particular to a fiber composite material and a preparation method thereof. The preparation method comprises: A) uniformly dispersing nanoparticles in a solvent to obtain a nanoparticle dispersion; B) uniformly spray-coating the nanoparticle dispersion on a chopped fiber nonwoven fabric, and drying the fabric to obtain a nano-modified chopped fiber nonwoven fabric; C) intercalating the nano-modified chopped fiber nonwoven fabric between fiber preforms, and subjecting the obtained material and a resin matrix to composite molding by a molding process to obtain a fiber composite material. In the present invention, firstly nanoparticles are uniformly dispersed in a solvent to obtain a nanoparticle dispersion; secondly, the chopped fiber and the nanoparticles cooperate to construct a multi-scale interlaminar toughening phase, which significantly improves the interlaminar fracture toughness of the fiber composite material.