Patents Assigned to Labsystems Oy
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Patent number: 5942124Abstract: The invention relates to a means for separating magnetic particles from a composition and for transferring them into a liquid in a vessel. The means comprises an elongated body (1) that comprises a device which can be used to align the longitudinal magnetic field of a protective cover with the lower end of the cover and eliminate the effect of the field from the lower end, and a tip part (8) at the lower end of the body, which is tapered in a concave manner. The means is especially well-adapted for transferring particles to very small vessels. The invention can be used in different applications, especially in the fields of biotechnology, biochemistry, and biomedicine.Type: GrantFiled: June 6, 1997Date of Patent: August 24, 1999Assignee: Labsystems, OyInventor: Jukka Tuunanen
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Patent number: 5879633Abstract: The object of the invention is a ratchet wheel pipette having a body and in it a cylinder (3) and a piston (12) and a filling and dispensing arrangement to draw liquid into the cylinder and to dispense it in smaller portions with the aid of the piston.Type: GrantFiled: April 15, 1997Date of Patent: March 9, 1999Assignee: Labsystems OyInventors: Jukka Tervamaki, Tapani Pullinen, Jouko Mikkonen, Kari Jarvimaki
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Patent number: 5804144Abstract: A piston pipette having pulling equipment for moving a piston upward and pushing equipment for moving the piston downward. The pushing equipment has a movable gripping device (5), which when moving downward is attached to the piston and transfers the piston downward, and a movable transfer device (4) extending below the gripping device. According to the structure a pipette is obtained which is gripped a pen-shape handle and with which liquid can be dosed to a desired place as exactly as possible.Type: GrantFiled: June 6, 1997Date of Patent: September 8, 1998Assignee: Labsystems OYInventor: Jukka Tervamaki
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Patent number: 5660797Abstract: A pipette receptacle, or tip, which is applied to the `jet` or aspirate/blow tube of the pipette proper, wherein the receptacle has a top end with integral sections of a material different from the of the main body of the receptacle. These sections of different material can include an outer collar, an inner collar, or an entire upper portion. A color coding can be included. Additionally, methods of making the receptacle is disclosed.Type: GrantFiled: May 3, 1995Date of Patent: August 26, 1997Assignee: Labsystems OyInventor: Kari Jarvimaki
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Patent number: 5647994Abstract: The invention concerns a method and apparatus for separating magnetic particles from a solution and transferring them into another solution. The apparatus includes a pipette container, a separation wall defining a separation chamber, and a magnet disposed at one of a first location adjacent an outer side of the separation wall and a second location within the separation chamber. The magnet is adapted to be brought into such a state that a magnetic field is applied to the solution so that the particles will gather onto one of an inner side of the separation wall when disposed in the first location, or on a collection surface of the magnet when disposed in the second location, or so that the magnetic field no longer keeps the magnetic particles on the separation wall or collection surface. The pipette container includes a suction cylinder for drawing the solution into and solution from the pipette container via a jet channel.Type: GrantFiled: June 20, 1994Date of Patent: July 15, 1997Assignee: Labsystems OyInventors: Jukka Tuunanen, Matti Korpela
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Patent number: 5474742Abstract: An apparatus for removing solid bodies from an array of reaction vessels includes a frame and a plurality of lifters, each lifter for holding a solid body disposed within a reaction vessel for removal therefrom. The lifters are mounted on the frame in an array corresponding to the array of reaction vessels such that the array of lifters is positionable within the array of vessels in a manner which permits placement of a solid body in each vessel on each lifter while the lifters are positioned in the vessels.Type: GrantFiled: February 23, 1995Date of Patent: December 12, 1995Assignee: Labsystems OyInventor: Tamara Tuuminen
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Patent number: 5470536Abstract: A cuvette matrix, having a row of attached cuvettes, from which it is possible to detach one cuvette to be placed in an opening in a stand. On the outer surface of each cuvette, at an angle from the longitudinal direction of the row of cuvettes, there is a holder member, which facilitates the cuvette to adhere to the sides of an opening. The holder member is moved into contact with the stand when the cuvette is turned in the opening.Type: GrantFiled: October 25, 1993Date of Patent: November 28, 1995Assignee: Labsystems OyInventor: Kari Jarvimaki
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Patent number: 5435197Abstract: A pipette provided with a tip remover, which pipette has a lever mechanism, in which the tip is pressed off the pipette. In this way, it has been possible to decrease the force needed for the loosening.Type: GrantFiled: April 19, 1993Date of Patent: July 25, 1995Assignee: Labsystems OyInventors: Juha Telimaa, Jukka Tervamaki
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Patent number: 5403553Abstract: A jet part pipette includes a body having an upper end and a lower end, the body having a longitudinal opening therein. A jet part is connected at the lower end of the body, and has an upper portion and a lower end. A replaceable jet container is connected to the lower end of the jet part, and has a lower element having a longitudinal opening therein. A movable rod extends through the jet part and through the longitudinal opening in the body, and has a manually operable upper end and a lower end engaging the lower element of the replaceable jet container for drawing liquid therein. A replaceable cover surrounds the upper portion of the jet part, and has a first end portion and a second end portion, the first end portion of the replaceable cover being detachably connected to an outer periphery of the upper portion of the jet part. The lower end of the jet part extends beyond the second end of the replaceable cover.Type: GrantFiled: April 9, 1993Date of Patent: April 4, 1995Assignee: Labsystems OyInventor: Mauno Heinonen
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Patent number: 5389341Abstract: A motor-driven knob pipette, wherein the displacement of a slidably transferable knob controls the movement of a piston by means of an electronic control system. The pipette is light to use, and the user has continuosly a good motory feel with the pipette.Type: GrantFiled: June 22, 1993Date of Patent: February 14, 1995Assignee: Labsystems OyInventors: Jukka Tuunanen, Juhaa K. Telimaa, Antti J. Keipi, Ari K. Kukkonen
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Patent number: 5355738Abstract: A positive-displacement pipette is provided comprising a longitudinally extending body portion having a bore passing therethrough, a hand grip portion disposed at one end of the body, and a tip portion coupled to and coaxially extending from the hand-grip portion. A cylinder is employed connected to and extending coaxially from the tip portion of the pipette, wherein the cylinder has a jet at its bottom end and a piston rod extending through the cylinder to the jet. A gripping arm in the form of a slidable sleeve is movably supported within the bore of the body and is adapted for gripping the piston rod by force applied to the slidable sleeve to thereby cause the sleeve to attach itself to the piston rod by friction. A device located on the hand grip portion of the body is provided for applying force to the slidable sleeve and hence to the piston rod extending through the cylinder to the jet.Type: GrantFiled: January 9, 1992Date of Patent: October 18, 1994Assignee: Labsystems OYInventor: Mauno Heinonen
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Patent number: 5216488Abstract: The invention relates to a method and apparatus for conducting light onto cuvettes in a photometer. Onto each cuvette in a row, there is successively conducted light through a moving light-cutting disc (8), which is provided with a slot (10) at each light path. Thus the light passing through the adjacent cuvette does not disturb the measurement.Type: GrantFiled: October 23, 1991Date of Patent: June 1, 1993Assignee: Labsystems OYInventors: Jukka Tguunanen, Aimo Kainiemi
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Patent number: 5192665Abstract: A method of determining the presence of epithelial lesions is provided wherein a sample of a body of fluid taken from an epithelial region suspected to have said lesions is tested for the presence of a proteolytic activity. The lesion is then treated by applying a therapeutically effective amount of a proteinase inhibitor in the form of a physiologically acceptable preparation, a pharmaceutical preparation of aprotinin being particularly preferred. A method for detecting allergic sensitivity is also disclosed.Type: GrantFiled: April 11, 1989Date of Patent: March 9, 1993Assignee: Labsystems, OyInventor: Eeva-Marjatta Salonen
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Patent number: 5160378Abstract: The invention concerns a washing device for treatment of rods attached to a plate with a solution. According to the invention the rods (6) are placed in ducts (4) through which the solution is passed. The invention can be used in particular in peptide syntheses and in immunological assay methods.Type: GrantFiled: September 21, 1990Date of Patent: November 3, 1992Assignee: Labsystems OyInventors: Jukka Tuunanen, Ale Narvanen, Mario Geysen
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Pharmaceutical preparation for promoting epithelial healing and prevention of epithelial destruction
Patent number: 5112805Abstract: A method of determining the presence of epithelial lesions is provided wherein a sample of a body fluid taken from an epithelial region suspected to have said lesions is tested for the presence of a proteolytic activity. The lesion is then treated by applying a therapeutically effective amount of a proteinase inhibitor in the form of a physiologically acceptable preparation, a pharmaceutical preparation of aprotinin being particularly preferred.Type: GrantFiled: April 11, 1989Date of Patent: May 12, 1992Assignee: Labsystems, OyInventor: Eeva-Marjatta Salonen -
Patent number: 5096672Abstract: The invention concerns a cuvette matrix and its tray. The matrix comprises adjacent cuvettes (2) connected with one another by flexible connecting elements (3). The tray has an aperture (8) for each well, with a flexible clamping element (9).Type: GrantFiled: August 24, 1990Date of Patent: March 17, 1992Assignee: Labsystems OyInventors: Jukka Tervamaki, Kari Vauramo
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Patent number: 5073346Abstract: The invention concerns an immunological assay system, wherein the inner face of the cuvettes is used as the solid phase. The equipment includes a displaceable carriage (8) for the cuvette set as well as, above the carriage, a dosage head (9), to which the liquid dosimeter (11) and the measurement device (19) are attached. All the operations take place automatically.Type: GrantFiled: July 13, 1989Date of Patent: December 17, 1991Assignee: Labsystems OYInventors: Paul Partanen, Helena Seppanen, Hannu Harjunmaa
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Patent number: 5063024Abstract: The invention concerns an immunological assay system, wherein the inner face of the cuvettes is used as the solid phase. The equipment includes a displaceable carriage (8) for the cuvette set as well as, above the carriage, a dosage head (9), to which the liquid dosimeter (11) and the measurement device (19) are attached. All the operations take place automatically.Type: GrantFiled: July 10, 1989Date of Patent: November 5, 1991Assignee: Labsystems OYInventors: Paul Partanen, Helena Seppanen, Hannu Harjunmaa
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Patent number: 5002737Abstract: The invention relates to an electrically operable pipette comprising a body member with upper and lower portions and a removable flanged cylinder assembly coupled to the lower portion of the body member via its flange. The cylinder assembly has confined in it, a piston which is vertically displaced by a motor confined in the body member, an adjustable limiter being provided for varying the stroke length of the piston and hence the volume of liquid displaced.Type: GrantFiled: November 15, 1988Date of Patent: March 26, 1991Assignee: Labsystems OyInventor: Jukka Tervamaki
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Patent number: RE34841Abstract: There is disclosed a micro-cuvette unit comprising a plurality of components in the form of a matrix which is arranged so that the cuvettes may be handled as one unit. The structural body of the micro-cuvette unit comprises a rectangular frame which is designed so that a plurality of cuvette components may be fitted to the frame, one after another. Each cuvette component comprises a plurality of cuvettes arranged in the form of a line or matrix and connected to each other directly or by means of support discs. The frame part of the micro-cuvette unit is open in the middle, at least within the area covered by the cuvettes in the cuvette components. The frame part contains two opposite sides which are provided with connecting means for joining the cuvette components to the frame part.Type: GrantFiled: September 25, 1992Date of Patent: January 31, 1995Assignee: Labsystems OyInventors: Osmo A. Suovaniemi, Pertti Ekholm, Paul Partanen