Abstract: Examples relate to an optical system and to an apparatus, method and computer program for an optical system. The optical imaging system comprises a camera for providing a camera image of a surface of an object. The optical imaging system further comprises one or more measurement modules for performing one or more measurements at one or more points of the surface of the object. The optical imaging system further comprises a display module. The optical imaging system further comprises a processing module configured to obtain the camera image of the surface of the object from the camera. The processing module is configured to obtain the one or more measurements at the one or more points of the surface of the object from the one or more measurement modules. The processing module is configured to determine a spatial location of the one or more points of the surface relative to the camera image.

Abstract: The present invention relates to an illumination filter system (2) for medical imaging, in particular multispectral fluorescence imaging, as performed e.g. in a microscope (1) or endoscope, such as a surgical microscope, in particular a surgical multispectral fluorescence microscope, comprising a first optical filter (35). The present invention also relates to an observation system (3) for medical imaging, in particular multispectral fluorescence imaging, as performed e.g. in a microscope (1) or endoscope, in particular a multispectral fluorescence microscope, comprising a beam splitter (21) adapted to split a light image (13) into a first light portion (16, 17) along a first light path (18) and a second light portion (20) along a second light path (19).

Abstract: A system for a microscope includes a display and an input interface. The system is configured to reproduce, in response to a user input to the input interface, a virtual tour of use of the microscope via the display. The system can be applied, for example, for teaching of microscopy at schools and universities.

Abstract: A microscope system for imaging at least one region of a sample includes: an image generating unit for microscopic imaging of a section of a sample region to be imaged acquired in an observation beam path; a movement unit for moving the section to be imaged into the observation beam path of the image generating unit; a graphic user interface displayed on a display for establishing a movement range corresponding to the sample region to be imaged by way of at least one user input, the graphic user interface displaying a coordinate system and, after input of at least one point in the displayed coordinate system, the movement range is established as a defined movement volume; and a control unit for activating the movement unit as a function of the defined movement volume so as to approach a set of sections corresponding to the defined movement volume in succession.

Abstract: The invention relates to a method, an image processor (26) and a medical observation device (1), such as a microscope or endoscope, for observing an object (4) containing a bolus of at least one fluorophore (12). The object (4) is preferably live tissue comprising several types (16, 18, 20) of tissue. According to the method, a set (34) of component signals (36) is provided. Each component signal (36) represents a fluorescence intensity development of the fluorophore (12) over time in a different type of tissue. A time series (8) of input frames (10) is accessed, one input frame (10) after the other. The input frames (10) represent electronically coded still images of the object (4) at subsequent time. Each input frame (10) contains at least one observation area (22) comprising at least one pixel (23).

Abstract: Examples relate to an illumination system for a microscope system, and to a system, method and computer program for a microscope system. The illumination system includes an illumination module for providing a spatially modulated illumination of a sample. The illumination system further includes one or more processors configured to determine a depth characteristic of the sample. The one or more processors is configured to control the illumination module based on the depth characteristic of the sample.

Abstract: Examples relate to a Light-Emitting Diode-based illumination system for a microscope, to a system, method and computer program for a microscope, and to a microscope system. The illumination system comprises one or more first LED-based light sources. The one or more first LED-based light sources are configured to emit light across a white light color spectrum. The illumination system comprises at least one optical filter. The at least one optical filter is arranged to filter the light emitted by the one or more first LED-based light sources. The illumination system comprises one or more second LED-based light sources. The one or more second LED-based light sources are configured to provide light having at least one peak at a wavelength that is tuned to an excitation wavelength of at least one fluorescent material.

Abstract: A module for a microscope stand comprises a control device with at least one computer hardware component being configured to control the microscope stand. The module further comprises a locating device configured to interact with another locating device formed in a housing of the microscope stand for mounting the module at a predetermined installation site within the housing.

Abstract: The invention relates to an augmented reality surgical microscope (1) having a camera (2), preferably a multispectral or hyperspectral camera. The augmented reality surgical microscope (1) retrieves input image data (22) of an object (8) comprising in particular live tissue (10). The input image data (22) comprise visible-light image data (26) as well as fluorescent-light image data (24) of at least one fluorophore (14). The augmented reality surgical microscope (1) permits the automatic identification and marking in pseudo-color (86) of various types of vascular plexus structures (54a 54b, 54c) and/or of blood flow direction (56) depending on the fluorescent-light image data (24). A pre-operative three-dimensional atlas (36) and/or ultrasound image data (39) may be elastically matched to the visible-light image data (26). The augmented reality surgical microscope (1) allows different combinations of the various image data to be output simultaneously to different displays (75).

Abstract: The invention relates to a medical device for the observation of a partly fluorescent object such as tissue comprising at least one fluorophore. The fluorophore absorbs light in at least one spectral excitation waveband and emits fluorescent light in at least one spectral emission waveband. In order to be able to observe also non-fluorescent regions in the tissue without complicated filter arrangement, the medical device according to the invention comprises at least one filter system which comprises, in a filter plane, comprises a filter area and a transmission window. The filter area comprises a band pass filter having at least one passband comprising the at least one excitation waveband. The transmission window has a passband which is wider than the passband of the filter area and is cross-shaped. The at least one filter system is configured to simultaneously receive light through the filter area and the entire transmission window.

Abstract: The present invention relates to a surgical microscope with a field of view and comprising an optical imaging system which images an inspection area which is at least partially located in the field of view, and to a method for a gesture control of a surgical microscope having an optical imaging system. The surgical microscope further comprises a gesture detection unit for detection of a movement of a surgical instrument, the gesture detection unit having a detection zone which is located between the inspection area and the optical imaging system and is spaced apart from the inspection area, and the gesture detection unit being configured to output a control signal to the optical imaging system depending on the movement of the surgical instrument in the detection zone, the optical imaging system being configured to alter its state depending on the control signal.

Abstract: A system comprises one or more processors and one or more storage devices. The system is configured to receive first image data of a first image of an object from a first image sensor and receive second image data of a fluorescence image of the object from a second image sensor. Further, the system is configured to process the first image data and the second image data and generate combined image data of an output image of the object in a linear color space based on the processed first image data and the processed second image data. Additionally, the system is configured to convert the combined image data to a non-linear color space representation of the output image.

Abstract: A digital microscope system comprises an imaging device configured to generate digital image data representing a target region of an object, the target region being determined by a changeable setting of the imaging device; and a controller configured to generate monitor image data corresponding to the digital image data generated in accordance with the setting, the monitor image data being configured to be displayed as a monitor image; wherein the controller is further configured to change the setting in response to a user input; and wherein the controller is further configured to compensate for a delay in updating the monitor image data in accordance with the changed setting by storing the digital image data generated in accordance with the unchanged setting in response to the user input and generating simulation monitor image data by performing digital image processing on the stored digital image data taking into account the changed setting, the simulation monitor image data being configured to be displayed

Abstract: Examples relate to an optical imaging system, and to a corresponding apparatus, method and computer program for an optical imaging system. The optical imaging system comprises one or more information sources for providing information about a current orientation of the optical imaging system towards at least a part of an object of interest. The optical imaging system comprises one or more output modules for providing guidance information for a user of the optical imaging system. The optical imaging system comprises a processing module configured to determine information on a desired orientation of the optical imaging system towards at least a part of the object of interest.

Abstract: Examples relate to apparatuses, methods and computer programs for a microscope system, more specifically, but not exclusively, to the use of two optical imaging modules to obtain image data having a first and a second field of view. The apparatus comprises an interface. The interface is suitable for obtaining first image data of a sample from a first optical imaging module. The first image data has a first field of view. The interface is suitable for obtaining second image data of the sample from a second optical imaging module. The second image data has a second field of view. The first field of view comprises the second field of view. The apparatus comprises a processing module. The processing module is configured to generate an image output signal for a display of the microscope system. In some embodiments, the processing module is configured to process the first image data to detect an abnormality outside the second field of view.

Abstract: Examples relate to a microscope system comprising a Light-Emitting Diode (LED)-based illumination system and at least one image sensor assembly, and to a corresponding system, method and computer program. The LED-based illumination system is configured to emit radiation power having at least one peak at a wavelength that is tuned to an excitation wavelength of at least one fluorescent material and/or to emit radiation power across a white light spectrum, with the light emitted across the white light spectrum being filtered such that light having a wavelength spectrum that coincides with at least one fluorescence emission wavelength spectrum of the at least one fluorescent material is attenuated or blocked. The at least one image sensor assembly is configured to generate image data, with the image data (at least) representing light reflected by a sample that is illuminated by the LED-based illumination system.

Abstract: Method for automatically setting at least a unit parameter for a medical unit or unit part with parameter values relating to a particular user. According to the method, a user is identified, a corresponding parameter set is selected and unit parameters are set with the selected parameter set. The preceding steps are only implemented when an authentication signal for activating the identification, selection and setting processes is received or present. The authentication signal can be based on use of a user priority database. The invention also relates to a corresponding medical unit and medical system.

Abstract: The invention relates to a medical device (1) for the observation of a partly fluorescent object (2) such as tissue (3) comprising at least one fluorophore (4). The fluorophore (4) absorbs light in at least one spectral excitation waveband (46) and emits fluorescent light in at least one spectral emission waveband (54). In order to be able to observe also non-fluorescent regions in the tissue (3) without complicated filter arrangement, the medical device (1) according to the invention comprises at least one filter system (16, 38) which comprises, in a filter plane (18), comprises a filter area (20) and a transmission window (22). The filter area (20) comprises a band pass filter (24) having at least one passband (44) comprising the at least one excitation waveband. The transmission window has a passband (48) which is wider than the passband (44) of the filter area (20). In particular, a filter layer (64) of the filter area (20) may be missing in the transmission window (20).

Abstract: A medical imaging apparatus (1) and method for imaging a light-sensitive object (2), such as tissue (3) of the eye (4), displays the object (2) in spectral bands (30) of the visible light range (37) in which the object is sensitive and cannot be illuminated. The apparatus (1) has a camera (8) for capturing input images (10) in which a spectral signature (36) of the object is represented by an input set (15) of spectral bands (16). The apparatus generates output images (22) in which the spectral signature (60) in the visible light range (37) is represented by an output set (29) of spectral bands (30). Replacing at least one input-only spectral band (38) in the input set (15) by at least one output-only spectral band (39) in the output set (29) enables capture of input images (10) in spectral bands (16) where the object (2) has less sensitivity, such as in the non-visible light-range (18), and display of the object (2) in spectral bands (30) where the object would be too sensitive for illumination (40).

Abstract: Examples relate to an optical system and to a corresponding apparatus, method and computer program. The optical system comprises a display module for providing a visual overlay to be overlaid over an object in an augmented reality or mixed reality environment. The optical system comprises at least one sensor for sensing at least one optical property of the object. The optical system comprises a processing module configured to determine the at least one optical property of the object using the at least one sensor. The processing module is configured to determine a visual contrast between the visual overlay to be overlaid over the object and the object, as perceived within a field of view of the augmented reality or mixed reality environment, based on the at least one optical property of the object.