Patents Assigned to Leisure, Inc.
  • Patent number: 11808776
    Abstract: There is provided a method of analyzing a biological sample component that allows easy and accurate quantification and counting of any of a plasma component and a blood cell component in a trace and unknown amount of a whole blood sample collected from a finger, for example. The method of the present invention is a method of analyzing a biological sample component in a trace amount of blood, comprising analyzing a diluent buffer into which the blood has been mixed and an internal standard substance and/or an external standard substance contained in the diluent buffer, calculating a dilution ratio, and analyzing a biological component in a plasma or serum component in the blood.
    Type: Grant
    Filed: April 28, 2020
    Date of Patent: November 7, 2023
    Assignee: Leisure, Inc.
    Inventors: Susumu Osawa, Shinya Sugimoto, Isao Yonekubo
  • Patent number: 11808777
    Abstract: There is provided a method of analyzing a biological sample component that allows easy and accurate quantification and counting of any of a plasma component and a blood cell component in a trace and unknown amount of a whole blood sample collected from a finger, for example. The method of the present invention is a method of analyzing a biological sample component in a trace amount of blood, comprising analyzing a diluent buffer into which the blood has been mixed and an internal standard substance and/or an external standard substance contained in the diluent buffer, calculating a dilution ratio, and analyzing a biological component in a plasma or serum component in the blood.
    Type: Grant
    Filed: April 28, 2020
    Date of Patent: November 7, 2023
    Assignee: Leisure, Inc.
    Inventors: Susumu Osawa, Shinya Sugimoto, Isao Yonekubo
  • Patent number: 11234479
    Abstract: A footwear device is provided having a deformable heel contact member. The heel contact member extends above a top portion of the footwear's sole and deforms into a cavity formed in the sole when the user's heel applies a force against the heel contact member. The heel contact member is resilient and returns to its original shape when the force against the heel contact member is eliminated. The heel contact member is particularly well suited to reduce heel slap of open heeled footwear.
    Type: Grant
    Filed: October 14, 2019
    Date of Patent: February 1, 2022
    Assignee: Leisure, Inc.
    Inventor: Louis F. Polk
  • Publication number: 20210073918
    Abstract: There are included: an examination result acquisition unit configured to acquire a result of a specimen examination using a specimen examination kit for a specimen examination subject; a health degree computation unit configured to derive a health degree of the specimen examination subject based on the result of the specimen examination, the health degree indicating a health state related to insurance subscription; an insurance information acquisition unit configured to acquire insurance information including an insurance premium based on the health degree of the specimen examination subject, from an insurance premium calculation device configured to calculate the insurance premium based on the health degree; an insurance proposition creation unit configured to create an insurance proposition including the insurance information; and an insurance proposition output unit configured to output the insurance proposition.
    Type: Application
    Filed: November 10, 2020
    Publication date: March 11, 2021
    Applicants: FUJIFILM Corporation, LEISURE, INC.
    Inventors: Yasuhisa KANEKO, Masakazu SUZUKI
  • Publication number: 20200319215
    Abstract: There is provided a method of analyzing a biological sample component that allows easy and accurate quantification and counting of any of a plasma component and a blood cell component in a trace and unknown amount of a whole blood sample collected from a finger, for example. The method of the present invention is a method of analyzing a biological sample component in a trace amount of blood, comprising analyzing a diluent buffer into which the blood has been mixed and an internal standard substance and/or an external standard substance contained in the diluent buffer, calculating a dilution ratio, and analyzing a biological component in a plasma or serum component in the blood.
    Type: Application
    Filed: April 28, 2020
    Publication date: October 8, 2020
    Applicant: Leisure, Inc.
    Inventors: Susumu Osawa, Shinya Sugimoto, Isao Yonekubo
  • Publication number: 20200319216
    Abstract: There is provided a method of analyzing a biological sample component that allows easy and accurate quantification and counting of any of a plasma component and a blood cell component in a trace and unknown amount of a whole blood sample collected from a finger, for example. The method of the present invention is a method of analyzing a biological sample component in a trace amount of blood, comprising analyzing a diluent buffer into which the blood has been mixed and an internal standard substance and/or an external standard substance contained in the diluent buffer, calculating a dilution ratio, and analyzing a biological component in a plasma or serum component in the blood.
    Type: Application
    Filed: April 28, 2020
    Publication date: October 8, 2020
    Applicant: Leisure, Inc.
    Inventors: Susumu Osawa, Shinya Sugimoto, Isao Yonekubo
  • Patent number: 10712354
    Abstract: There is provided a method of analyzing a biological sample component that allows easy and accurate quantification and counting of any of a plasma component and a blood cell component in a trace and unknown amount of a whole blood sample collected from a finger, for example. The method of the present invention is a method of analyzing a biological sample component in a trace amount of blood, comprising analyzing a diluent buffer into which the blood has been mixed and an internal standard substance and/or an external standard substance contained in the diluent buffer, calculating a dilution ratio, and analyzing a biological component in a plasma or serum component in the blood.
    Type: Grant
    Filed: July 6, 2015
    Date of Patent: July 14, 2020
    Assignee: Leisure, Inc.
    Inventors: Susumu Osawa, Shinya Sugimoto, Isao Yonekubo
  • Publication number: 20200037695
    Abstract: A footwear device is provided having a deformable heel contact member. The heel contact member extends above a top portion of the footwear's sole and deforms into a cavity formed in the sole when the user's heel applies a force against the heel contact member. The heel contact member is resilient and returns to its original shape when the force against the heel contact member is eliminated. The heel contact member is particularly well suited to reduce heel slap of open heeled footwear.
    Type: Application
    Filed: October 14, 2019
    Publication date: February 6, 2020
    Applicant: Leisure, Inc.
    Inventor: Louis F. Polk
  • Patent number: 10441021
    Abstract: A footwear device is provided having a deformable heel contact member. The heel contact member extends above a top portion of the footwear's sole and deforms into a cavity formed in the sole when the user's heel applies a force against the heel contact member. The heel contact member is resilient and returns to its original shape when the force against the heel contact member is eliminated. The heel contact member is particularly well suited to reduce heel slap of open heeled footwear.
    Type: Grant
    Filed: June 22, 2017
    Date of Patent: October 15, 2019
    Assignee: Leisure, Inc.
    Inventor: Louis F. Polk
  • Patent number: 10241012
    Abstract: A method for separating plasma in a minute amount of a blood sample diluted with a blood dilution buffer is provided. When a blood dilution buffer is added to a minute amount of blood (about 20 to 100 ?L) so as to assay the biological blood components in the resulting diluted plasma, it is necessary to separately store and transfer the diluted blood cell component and the diluted plasma component. The present inventors found that it is possible to separate diluted plasma from diluted blood cells using a polymer gelling agent for plasma separation by means of putting a polymer gel for plasma separation in the container with a blood dilution buffer. In such case, diluted blood cells are transferred to the lower portion of the polymer gelling agent and dilute plasma is transferred to the upper portion of the same. Assay of the biological blood components using a minute amount of blood can be utilized for early detection of health status, diseases, and presymptomatic states.
    Type: Grant
    Filed: June 12, 2014
    Date of Patent: March 26, 2019
    Assignee: Leisure, Inc.
    Inventors: Shinya Sugimoto, Isao Yonekubo, Masato Kawaguchi, Susumu Osawa
  • Patent number: 10238983
    Abstract: A wobbling toy is configured to spontaneously re-orient itself in an upright position solely under the force of gravity. The self-righting toy includes a weight that is confined to and movable along a pathway such that the weight defines a dynamic mass that is sufficient to cause the housing to spontaneously pivot along a convex outer surface profile in coordination with a position of the weight in the pathway. The self-righting toy is configured to maintain a positional relationship of the weight so that the housing is spontaneously pivotable along the convex surface without external force supplied by a user.
    Type: Grant
    Filed: January 13, 2017
    Date of Patent: March 26, 2019
    Assignee: Leisure, Inc.
    Inventor: Louis Frederick Polk
  • Publication number: 20170205433
    Abstract: There is provided a method of analyzing a biological sample component that allows easy and accurate quantification and counting of any of a plasma component and a blood cell component in a trace and unknown amount of a whole blood sample collected from a finger, for example. The method of the present invention is a method of analyzing a biological sample component in a trace amount of blood, comprising analyzing a diluent buffer into which the blood has been mixed and an internal standard substance and/or an external standard substance contained in the diluent buffer, calculating a dilution ratio, and analyzing a biological component in a plasma or serum component in the blood.
    Type: Application
    Filed: July 6, 2015
    Publication date: July 20, 2017
    Applicant: Leisure, Inc.
    Inventors: Susumu Osawa, Shinya Sugimoto, Isao Yonekubo
  • Publication number: 20170131189
    Abstract: A method for separating plasma in a minute amount of a blood sample diluted with a blood dilution buffer is provided. When a blood dilution buffer is added to a minute amount of blood (about 20 to 100 ?L) so as to assay the biological blood components in the resulting diluted plasma, it is necessary to separately store and transfer the diluted blood cell component and the diluted plasma component. The present inventors found that it is possible to separate diluted plasma from diluted blood cells using a polymer gelling agent for plasma separation by means of putting a polymer gel for plasma separation in the container with a blood dilution buffer. In such case, diluted blood cells are transferred to the lower portion of the polymer gelling agent and dilute plasma is transferred to the upper portion of the same. Assay of the biological blood components using a minute amount of blood can be utilized for early detection of health status, diseases, and presymptomatic states.
    Type: Application
    Filed: June 12, 2014
    Publication date: May 11, 2017
    Applicant: Leisure, Inc.
    Inventors: Shinya Sugimoto, Isao Yonekubo, Masato Kawaguchi, Susumu Osawa
  • Patent number: 7549430
    Abstract: A table and umbrella assembly capable of withstanding lateral forces by providing an overall center of gravity below its top. Two collar lock assemblies are removably mounted to a pole assembly that passes through the top center. The umbrella pole assembly, when tubular, may include a weight introduced to the lowermost member. The weight may be either solid or liquid and does not extend above the top.
    Type: Grant
    Filed: February 15, 2007
    Date of Patent: June 23, 2009
    Assignee: Furniture Leisure, Inc.
    Inventor: John Gravlee
  • Patent number: 7340832
    Abstract: A method of fabricating a motorhome, wherein the motorhome comprises a chassis, a vehicle frame, and a coach body. In one embodiment, the method begins by prefabricating the frame by joining a plurality of parallel elongate members with cross-tie members. The frame is prefabricated separate from the chassis, and in one embodiment, the frame is prefabricated upside down such that the underside of the frame is accessible for attachment of a plurality of bulkheads. Then, the frame is rotated upright and positioned atop the chassis. In one embodiment, the rails of the chassis lie inside a channel defined by the plurality of bulkheads. Next, additional bulkheads are joined to the frame and chassis to further interconnect the frame and chassis. Preferably, the additional bulkheads comprise an opening such that the additional bulkheads can surround the chassis on all sides. Finally, the coach body is assembled on the frame.
    Type: Grant
    Filed: October 26, 2004
    Date of Patent: March 11, 2008
    Assignee: Alfa Leisure, Inc.
    Inventor: Johnnie Crean
  • Patent number: 7338109
    Abstract: A vehicle frame with a low profile is designed to be suitable for attaching directly to an incomplete, preassembled motorized chassis to construct a motorhome. The vehicle frame includes planar bulkheads and a storage area floor that are attached to the frame and to the chassis so as to create a three-dimensional space frame that is highly resistant to bending and twisting forces as well as storage areas that extend the width of the motorhome. The motorhome with the frame mounts a heating, ventilation, and air conditioning (HVAC) system as well as heavy holding tanks within or below the plane of the vehicle frame so as to lower the center of mass of the motorhome to thereby improve vehicle handling and safety. Placement of the HVAC system within and/or below the vehicle frame obviates the need to position HVAC components on the roof of the motorhome thereby further lowering the center of mass and eliminating a source of liquid water condensation above the living space of the motorhome.
    Type: Grant
    Filed: April 4, 2006
    Date of Patent: March 4, 2008
    Assignee: Alfa Leisure, Inc.
    Inventor: Johnnie Robert Crean
  • Patent number: 7334827
    Abstract: The present teachings describe a method and system for deploying and retracting recreational vehicle slide-outs. The recreational vehicle includes a vertical movement member positioned in a recessed region formed in an exterior wall of the recreational vehicle so as to be adjacent the lower portion of an opening formed therein. At least a portion of the floor of the slide-out glides along the vertical movement member during retraction so as to lift the slide-out housing to the second level and glides along the vertical movement member during deployment so as to lower the slide-out housing to the third level.
    Type: Grant
    Filed: January 19, 2006
    Date of Patent: February 26, 2008
    Assignee: Alfa Leisure, Inc.
    Inventor: Johnnie R. Crean
  • Patent number: 7328927
    Abstract: A securing mechanism for use with a recreational vehicle (RV) slide out assembly. The securing mechanism structurally interconnects the slide out assembly to the RV when the slide out assembly is in a retracted position and when it is in an extended position. Specifically, loads in the RV induced from the road, from passengers, from equipment, and other various sources are distributed through the slide out assembly. Advantageously, flexure of the RV walls around the slide out opening is reduced. As a result, walls and their fixtures are less likely to be damaged due to flexure, seals between the RV walls and the slide out are more likely to stay intact, and the size of slide outs can be increased without compromising the structural integrity of the RV.
    Type: Grant
    Filed: August 1, 2006
    Date of Patent: February 12, 2008
    Assignee: Alfa Leisure, Inc.
    Inventor: Johnnie R. Crean
  • Patent number: 7323144
    Abstract: A simplified collecting operation of a biological sample is provided, which enables reduction of the examination cost.
    Type: Grant
    Filed: March 7, 2003
    Date of Patent: January 29, 2008
    Assignee: Leisure, Inc.
    Inventors: Kousuke Arai, Noriyuki Nomura
  • Patent number: D813524
    Type: Grant
    Filed: November 20, 2013
    Date of Patent: March 27, 2018
    Assignee: Active Leisure Inc.
    Inventor: Oliver Joen-an Ma