Patents Assigned to Leisure, Inc.
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Patent number: 11808776Abstract: There is provided a method of analyzing a biological sample component that allows easy and accurate quantification and counting of any of a plasma component and a blood cell component in a trace and unknown amount of a whole blood sample collected from a finger, for example. The method of the present invention is a method of analyzing a biological sample component in a trace amount of blood, comprising analyzing a diluent buffer into which the blood has been mixed and an internal standard substance and/or an external standard substance contained in the diluent buffer, calculating a dilution ratio, and analyzing a biological component in a plasma or serum component in the blood.Type: GrantFiled: April 28, 2020Date of Patent: November 7, 2023Assignee: Leisure, Inc.Inventors: Susumu Osawa, Shinya Sugimoto, Isao Yonekubo
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Patent number: 11808777Abstract: There is provided a method of analyzing a biological sample component that allows easy and accurate quantification and counting of any of a plasma component and a blood cell component in a trace and unknown amount of a whole blood sample collected from a finger, for example. The method of the present invention is a method of analyzing a biological sample component in a trace amount of blood, comprising analyzing a diluent buffer into which the blood has been mixed and an internal standard substance and/or an external standard substance contained in the diluent buffer, calculating a dilution ratio, and analyzing a biological component in a plasma or serum component in the blood.Type: GrantFiled: April 28, 2020Date of Patent: November 7, 2023Assignee: Leisure, Inc.Inventors: Susumu Osawa, Shinya Sugimoto, Isao Yonekubo
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Patent number: 11234479Abstract: A footwear device is provided having a deformable heel contact member. The heel contact member extends above a top portion of the footwear's sole and deforms into a cavity formed in the sole when the user's heel applies a force against the heel contact member. The heel contact member is resilient and returns to its original shape when the force against the heel contact member is eliminated. The heel contact member is particularly well suited to reduce heel slap of open heeled footwear.Type: GrantFiled: October 14, 2019Date of Patent: February 1, 2022Assignee: Leisure, Inc.Inventor: Louis F. Polk
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Publication number: 20210073918Abstract: There are included: an examination result acquisition unit configured to acquire a result of a specimen examination using a specimen examination kit for a specimen examination subject; a health degree computation unit configured to derive a health degree of the specimen examination subject based on the result of the specimen examination, the health degree indicating a health state related to insurance subscription; an insurance information acquisition unit configured to acquire insurance information including an insurance premium based on the health degree of the specimen examination subject, from an insurance premium calculation device configured to calculate the insurance premium based on the health degree; an insurance proposition creation unit configured to create an insurance proposition including the insurance information; and an insurance proposition output unit configured to output the insurance proposition.Type: ApplicationFiled: November 10, 2020Publication date: March 11, 2021Applicants: FUJIFILM Corporation, LEISURE, INC.Inventors: Yasuhisa KANEKO, Masakazu SUZUKI
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Publication number: 20200319215Abstract: There is provided a method of analyzing a biological sample component that allows easy and accurate quantification and counting of any of a plasma component and a blood cell component in a trace and unknown amount of a whole blood sample collected from a finger, for example. The method of the present invention is a method of analyzing a biological sample component in a trace amount of blood, comprising analyzing a diluent buffer into which the blood has been mixed and an internal standard substance and/or an external standard substance contained in the diluent buffer, calculating a dilution ratio, and analyzing a biological component in a plasma or serum component in the blood.Type: ApplicationFiled: April 28, 2020Publication date: October 8, 2020Applicant: Leisure, Inc.Inventors: Susumu Osawa, Shinya Sugimoto, Isao Yonekubo
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Publication number: 20200319216Abstract: There is provided a method of analyzing a biological sample component that allows easy and accurate quantification and counting of any of a plasma component and a blood cell component in a trace and unknown amount of a whole blood sample collected from a finger, for example. The method of the present invention is a method of analyzing a biological sample component in a trace amount of blood, comprising analyzing a diluent buffer into which the blood has been mixed and an internal standard substance and/or an external standard substance contained in the diluent buffer, calculating a dilution ratio, and analyzing a biological component in a plasma or serum component in the blood.Type: ApplicationFiled: April 28, 2020Publication date: October 8, 2020Applicant: Leisure, Inc.Inventors: Susumu Osawa, Shinya Sugimoto, Isao Yonekubo
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Patent number: 10712354Abstract: There is provided a method of analyzing a biological sample component that allows easy and accurate quantification and counting of any of a plasma component and a blood cell component in a trace and unknown amount of a whole blood sample collected from a finger, for example. The method of the present invention is a method of analyzing a biological sample component in a trace amount of blood, comprising analyzing a diluent buffer into which the blood has been mixed and an internal standard substance and/or an external standard substance contained in the diluent buffer, calculating a dilution ratio, and analyzing a biological component in a plasma or serum component in the blood.Type: GrantFiled: July 6, 2015Date of Patent: July 14, 2020Assignee: Leisure, Inc.Inventors: Susumu Osawa, Shinya Sugimoto, Isao Yonekubo
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Publication number: 20200037695Abstract: A footwear device is provided having a deformable heel contact member. The heel contact member extends above a top portion of the footwear's sole and deforms into a cavity formed in the sole when the user's heel applies a force against the heel contact member. The heel contact member is resilient and returns to its original shape when the force against the heel contact member is eliminated. The heel contact member is particularly well suited to reduce heel slap of open heeled footwear.Type: ApplicationFiled: October 14, 2019Publication date: February 6, 2020Applicant: Leisure, Inc.Inventor: Louis F. Polk
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Patent number: 10441021Abstract: A footwear device is provided having a deformable heel contact member. The heel contact member extends above a top portion of the footwear's sole and deforms into a cavity formed in the sole when the user's heel applies a force against the heel contact member. The heel contact member is resilient and returns to its original shape when the force against the heel contact member is eliminated. The heel contact member is particularly well suited to reduce heel slap of open heeled footwear.Type: GrantFiled: June 22, 2017Date of Patent: October 15, 2019Assignee: Leisure, Inc.Inventor: Louis F. Polk
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Patent number: 10241012Abstract: A method for separating plasma in a minute amount of a blood sample diluted with a blood dilution buffer is provided. When a blood dilution buffer is added to a minute amount of blood (about 20 to 100 ?L) so as to assay the biological blood components in the resulting diluted plasma, it is necessary to separately store and transfer the diluted blood cell component and the diluted plasma component. The present inventors found that it is possible to separate diluted plasma from diluted blood cells using a polymer gelling agent for plasma separation by means of putting a polymer gel for plasma separation in the container with a blood dilution buffer. In such case, diluted blood cells are transferred to the lower portion of the polymer gelling agent and dilute plasma is transferred to the upper portion of the same. Assay of the biological blood components using a minute amount of blood can be utilized for early detection of health status, diseases, and presymptomatic states.Type: GrantFiled: June 12, 2014Date of Patent: March 26, 2019Assignee: Leisure, Inc.Inventors: Shinya Sugimoto, Isao Yonekubo, Masato Kawaguchi, Susumu Osawa
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Patent number: 10238983Abstract: A wobbling toy is configured to spontaneously re-orient itself in an upright position solely under the force of gravity. The self-righting toy includes a weight that is confined to and movable along a pathway such that the weight defines a dynamic mass that is sufficient to cause the housing to spontaneously pivot along a convex outer surface profile in coordination with a position of the weight in the pathway. The self-righting toy is configured to maintain a positional relationship of the weight so that the housing is spontaneously pivotable along the convex surface without external force supplied by a user.Type: GrantFiled: January 13, 2017Date of Patent: March 26, 2019Assignee: Leisure, Inc.Inventor: Louis Frederick Polk
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Publication number: 20170205433Abstract: There is provided a method of analyzing a biological sample component that allows easy and accurate quantification and counting of any of a plasma component and a blood cell component in a trace and unknown amount of a whole blood sample collected from a finger, for example. The method of the present invention is a method of analyzing a biological sample component in a trace amount of blood, comprising analyzing a diluent buffer into which the blood has been mixed and an internal standard substance and/or an external standard substance contained in the diluent buffer, calculating a dilution ratio, and analyzing a biological component in a plasma or serum component in the blood.Type: ApplicationFiled: July 6, 2015Publication date: July 20, 2017Applicant: Leisure, Inc.Inventors: Susumu Osawa, Shinya Sugimoto, Isao Yonekubo
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Publication number: 20170131189Abstract: A method for separating plasma in a minute amount of a blood sample diluted with a blood dilution buffer is provided. When a blood dilution buffer is added to a minute amount of blood (about 20 to 100 ?L) so as to assay the biological blood components in the resulting diluted plasma, it is necessary to separately store and transfer the diluted blood cell component and the diluted plasma component. The present inventors found that it is possible to separate diluted plasma from diluted blood cells using a polymer gelling agent for plasma separation by means of putting a polymer gel for plasma separation in the container with a blood dilution buffer. In such case, diluted blood cells are transferred to the lower portion of the polymer gelling agent and dilute plasma is transferred to the upper portion of the same. Assay of the biological blood components using a minute amount of blood can be utilized for early detection of health status, diseases, and presymptomatic states.Type: ApplicationFiled: June 12, 2014Publication date: May 11, 2017Applicant: Leisure, Inc.Inventors: Shinya Sugimoto, Isao Yonekubo, Masato Kawaguchi, Susumu Osawa
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Patent number: 7549430Abstract: A table and umbrella assembly capable of withstanding lateral forces by providing an overall center of gravity below its top. Two collar lock assemblies are removably mounted to a pole assembly that passes through the top center. The umbrella pole assembly, when tubular, may include a weight introduced to the lowermost member. The weight may be either solid or liquid and does not extend above the top.Type: GrantFiled: February 15, 2007Date of Patent: June 23, 2009Assignee: Furniture Leisure, Inc.Inventor: John Gravlee
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Patent number: 7340832Abstract: A method of fabricating a motorhome, wherein the motorhome comprises a chassis, a vehicle frame, and a coach body. In one embodiment, the method begins by prefabricating the frame by joining a plurality of parallel elongate members with cross-tie members. The frame is prefabricated separate from the chassis, and in one embodiment, the frame is prefabricated upside down such that the underside of the frame is accessible for attachment of a plurality of bulkheads. Then, the frame is rotated upright and positioned atop the chassis. In one embodiment, the rails of the chassis lie inside a channel defined by the plurality of bulkheads. Next, additional bulkheads are joined to the frame and chassis to further interconnect the frame and chassis. Preferably, the additional bulkheads comprise an opening such that the additional bulkheads can surround the chassis on all sides. Finally, the coach body is assembled on the frame.Type: GrantFiled: October 26, 2004Date of Patent: March 11, 2008Assignee: Alfa Leisure, Inc.Inventor: Johnnie Crean
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Patent number: 7338109Abstract: A vehicle frame with a low profile is designed to be suitable for attaching directly to an incomplete, preassembled motorized chassis to construct a motorhome. The vehicle frame includes planar bulkheads and a storage area floor that are attached to the frame and to the chassis so as to create a three-dimensional space frame that is highly resistant to bending and twisting forces as well as storage areas that extend the width of the motorhome. The motorhome with the frame mounts a heating, ventilation, and air conditioning (HVAC) system as well as heavy holding tanks within or below the plane of the vehicle frame so as to lower the center of mass of the motorhome to thereby improve vehicle handling and safety. Placement of the HVAC system within and/or below the vehicle frame obviates the need to position HVAC components on the roof of the motorhome thereby further lowering the center of mass and eliminating a source of liquid water condensation above the living space of the motorhome.Type: GrantFiled: April 4, 2006Date of Patent: March 4, 2008Assignee: Alfa Leisure, Inc.Inventor: Johnnie Robert Crean
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Patent number: 7334827Abstract: The present teachings describe a method and system for deploying and retracting recreational vehicle slide-outs. The recreational vehicle includes a vertical movement member positioned in a recessed region formed in an exterior wall of the recreational vehicle so as to be adjacent the lower portion of an opening formed therein. At least a portion of the floor of the slide-out glides along the vertical movement member during retraction so as to lift the slide-out housing to the second level and glides along the vertical movement member during deployment so as to lower the slide-out housing to the third level.Type: GrantFiled: January 19, 2006Date of Patent: February 26, 2008Assignee: Alfa Leisure, Inc.Inventor: Johnnie R. Crean
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Patent number: 7328927Abstract: A securing mechanism for use with a recreational vehicle (RV) slide out assembly. The securing mechanism structurally interconnects the slide out assembly to the RV when the slide out assembly is in a retracted position and when it is in an extended position. Specifically, loads in the RV induced from the road, from passengers, from equipment, and other various sources are distributed through the slide out assembly. Advantageously, flexure of the RV walls around the slide out opening is reduced. As a result, walls and their fixtures are less likely to be damaged due to flexure, seals between the RV walls and the slide out are more likely to stay intact, and the size of slide outs can be increased without compromising the structural integrity of the RV.Type: GrantFiled: August 1, 2006Date of Patent: February 12, 2008Assignee: Alfa Leisure, Inc.Inventor: Johnnie R. Crean
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Patent number: 7323144Abstract: A simplified collecting operation of a biological sample is provided, which enables reduction of the examination cost.Type: GrantFiled: March 7, 2003Date of Patent: January 29, 2008Assignee: Leisure, Inc.Inventors: Kousuke Arai, Noriyuki Nomura
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Patent number: D813524Type: GrantFiled: November 20, 2013Date of Patent: March 27, 2018Assignee: Active Leisure Inc.Inventor: Oliver Joen-an Ma