Abstract: The electrolysis water-making apparatus (A) which is an apparatus for making electrolysis water (W5) by electrolyzing a raw material solution (W1, W3) including a chlorine ion includes: an electrolytic cell (2); a raw material solution feed pump (3) used to supply the raw material solution (W1, W3) to the electrolytic cell (2); and a pipe (32, 36) connecting an outlet (3b) of the raw material solution feed pump (3) allowing the raw material solution (W1, W3) to be discharged therefrom and an inlet (26) allowing the raw material solution (W1, W3) to flow into the electrolytic cell (2). In addition, the raw material solution feed pump (3) is provided so that the outlet (3b) is disposed on a lower side of the inlet (26).

Abstract: Live cells of microorganism in a test sample are detected by distinguishing the live cells from dead cells or injured cells by the following steps of: a) adding an agent capable of covalently binding to DNA or RNA by irradiation with light having a wavelength of 350 nm to 700 nm to the test sample; b) irradiating the test sample to which the cross-linking agent is added with light having a wavelength of 350 nm to 700 nm; c) amplifying a target region of DNA or RNA of the microorganism contained in the test sample by a nucleic acid amplification method in the presence of an agent for suppressing an action of a nucleic acid amplification inhibitory substance, without extracting nucleic acids from the cells; and d) analyzing the amplified product.

Abstract: The electrolysis water-making apparatus (A) includes: an electrolytic cell (2); a raw material solution feed pump (3) used to supply the raw material solution (W1, W3) to the electrolytic cell (2); a raw material solution pipe (32, 36) connecting an outlet (3b) of the raw material solution feed pump (3) and an inlet (26) of the electrolytic cell (2); and an electrolyzed solution advection-deterring portion (40) formed in the raw material solution pipe (32, 36) between the outlet (3b) and the inlet (26). The raw material solution feed pump (3) is provided so that the outlet (3b) is disposed on an upper side of the inlet (26). A pitched pipe (32c) in which an end thereof near the inlet (26) is disposed on an upper side of another end thereof near the outlet (3b) is provided in at least a part of the electrolyzed solution advection-deterring portion (40).

Abstract: A peptide dimer comprising a peptide consisting of the amino acid sequence of SEQ ID NO: 1 and a peptide consisting of any one of the amino acid sequences of SEQ ID NOS: 2 to 4, wherein the peptide consisting of the amino acid sequence of SEQ ID NO: 1 and the peptide consisting of any one of the amino acid sequences of SEQ ID NOS: 2 to 4 are bound through a disulfide bond between a cysteine residue of each peptide is used as an active ingredient of an agent for promoting proliferation of one or more bacterium selected from the group consisting of Bifidobacterium infantis and Bifidobacterium breve.

Abstract: A power control device supplies electrolysis voltage and electrolysis current, based on input direct-current power, to an electrolytic cell for manufacturing electrolysis water by electrolysis on a raw material solution by means of electric current applied between an anode and a cathode.

Abstract: The Lactobacillus paracasei MCC1849 (NITE BP-01633) strain, which has a high IL-12 production-promoting action, is used as an ingredient of a drug, food or drink, or feed used for promotion of IL-12 production, immunostimulation, antivirus, or the like.

Abstract: The invention is a bipolar-electrode electrolytic cell (1) which includes a chassis (2), an electrode plate (3) and a plate-shape spacer (4) having a concavity (25) disposing the electrode plate (3), wherein an unit cell (C), which is formed by connecting a plurality of spacers (4) in which the electrode plate (3) is disposed on the concavity (25) so that one plate surface of the electrode plate (3) is directed to one direction, is disposed inside the chassis (2). The bipolar-electrode electrolytic cell (1) includes engaged portions (35, 50 and 51) which are provided on any one of the concavity (25) of the spacer (4) or the electrode plate (3) and engaging portions (10A and 10B) which are formed the other portion with respect to the one portion.

Abstract: A packaging material 1 is configured to pack a viscous product having one surface, an opposite surface, and side surfaces. The packaging material 1 includes a sheet 2 having a first surface portion 7 configured to cover the one surface of the viscous product, side surface portions 8-1 to 8-4 configured to cover the side surfaces, and second surface portions 9-1 to 9-4 disposed at the opposite surface, and tear tape 3 adhered to the sheet to cut the sheet. The tear tape is provided to start from the side surface portion or the second surface portion and to be branched into a first branched tape 3a and a second branched tape 3b across the first surface portion.

Abstract: An extract of Citrus depressa, preferably a water and/or organic solvent extract of a fruit of leaf of Citrus depressa, a supercritical extract of a fruit of leaf of Citrus depressa, or a subcritical extract of a fruit of leaf of Citrus depressa, which comprise 0.3 mass % or more of a polymethoxyflavonoid more than in terms of solid matter, for example, an extract of Citrus depressa comprising 0.2 mass % or more of nobiletin and/or 0.1 mass % or more of tangeretin in terms of solid matter, or a polymethoxyflavonoid such as nobiletin or tangeretin is used as an active ingredient of an IGF-1 production-promoting agent.

Abstract: A processed cheese is produced by producing a natural cheese (N) via an acidification step, a coagulation step and a dehydration step described below, and then using the obtained natural cheese (N) for at least 5% by mass of an ingredient cheese. The acidification step is a step of acidifying a milk to obtain an acidified milk having a pH of 5.8 to 6.4, in which an acid component is added to the milk to achieve the required pH for the acidified milk, the coagulation step is a step of obtaining a curd by adding a milk coagulating enzyme to the acidified milk to cause coagulation, without adding a lactic acid bacterium starter, and the dehydration step is a step of obtaining the natural cheese (N) by separating whey from the curd, and includes an enzyme inactivation step of inactivating the milk coagulating enzyme by cooking the curd to at least 55° C. at a rate of temperature increase of not more than 1° C. per minute.

Abstract: An electrolysis water-making apparatus (1A) includes a casing (20), an electrolytic cell (4) installed in the casing (20) and configured to perform electrolysis on a raw material solution, a raw material solution feed pump (10) configured to pump the raw material solution to the electrolytic cell (4), and a diluting unit (26) configured to dilute electrolyzed products extracted from the electrolytic cell (4) with dilution water; and provided with a bracket (30) configured to integrally attach the electrolytic cell (4) and the raw material solution feed pump (10), and detachably fixed to the inside of the casing (20) in a state in which the electrolytic cell (4) and the raw material solution feed pump (10) are attached thereto.

Abstract: Live cells of a microorganism in a test sample are detected by the following steps: a) the step of treating the test sample with a topoisomerase poison and/or a DNA gyrase poison, b) the step of extracting DNA from the test sample, and amplifying a target region of the extracted DNA by PCR, and c) the step of analyzing an amplification product.

Abstract: This electrolyzed water production device (1A) includes an electrolytic bath (3) that discharges electrolyzed products generated by electrolysis of a raw material solution from an outlet (2); a mixing section (4) that mixes the electrolyzed products with dilution water to generate electrolyzed water; and a mounting section (6) that has a connecting section (19) where a hole section (20) connected to the outlet (2) is formed and that allows the electrolytic bath (3) to be detachably mounted thereto. By moving either the electrolytic bath (3) or the connecting section (6) relative to the other, the communication between the outlet (2) and the hole section (20) is allowed or released. Additionally, the electrolytic bath (3) is mounted on the mounting section (6) in a state where the inside of the electrolytic bath (3) is filled with a predetermined amount of the raw material solution and sealed in advance and an additional raw material solution cannot be injected thereinto.

Abstract: An antimicrobial activity enhancing agent for lactoferrin or a lactoferrin hydrolysate, which contains ribonuclease-4 as an active ingredient, and a method for producing an antimicrobial activity enhancing agent for lactoferrin or a lactoferrin hydrolysate, which comprises (a) the step of contacting raw milk with a cation exchange resin to adsorb proteins in the raw milk to the cation exchange resin, (b) the step of washing the cation exchange resin having undergone the adsorption treatment, and flowing an elution solvent to elute a protein fraction having an isoelectric point of 8.0 to 10.0, and (c) the step of subjecting the eluted protein fraction to gel filtration using a gel filtration carrier to collect a fraction of a molecular weight of 30 kDa or less.

Abstract: An excellent peptidyl peptidase-IV inhibitor and the like are provided. A peptide consisting of Val-Pro-X wherein X represents an amino acid residue (except for L-proline residue); the aforementioned X is preferably one selected from a basic amino acid residue, an aliphatic neutral amino acid residue, an amide group-carrying neutral amino acid residue, or an aromatic group-carrying neutral amino acid residue; the aforementioned X is preferably one selected from an alanine residue, a glutamine residue, a methionine residue, an asparagine residue, a glycine residue, a valine residue, a tyrosine residue, a serine residue, and a lysine residue; a dipeptidyl peptidase-IV inhibitor, a blood sugar rise suppressing agent, a vascular endothelial disorder suppressing agent, and an angiotensin converting enzyme inhibitor containing the aforementioned peptide as an active ingredient.

Abstract: The present invention relates to a method of treating a liquid composition containing lacto-N-biose, the method including: preparing a liquid composition containing lacto-N-biose having a pH at 25° C. of not less than 2.0 and not more than 5.5, and heating the liquid composition at a temperature of 65° C. or higher. The present invention can provide a treatment method that enables thermal decomposition of lacto-N-biose to be suppressed when a liquid composition containing lacto-N-biose is heated at a temperature of 65° C. or higher, a liquid preparation containing lacto-N-biose that is treated using the treatment method, a dried product produced from such a liquid preparation containing lacto-N-biose, and a method of producing a product containing lacto-N-biose.

Abstract: A peptide dimer comprising a peptide consisting of the amino acid sequence of SEQ ID NO: 1 and a peptide consisting of any one of the amino acid sequences of SEQ ID NOS: 2 to 4, wherein the peptide consisting of the amino acid sequence of SEQ ID NO: 1 and the peptide consisting of any one of the amino acid sequences of SEQ ID NOS: 2 to 4 are bound through a disulfide bond between a cysteine residue of each peptide is used as an active ingredient of an agent for promoting proliferation of one or more bacterium selected from the group consisting of Bifidobacterium infantis and Bifidobacterium breve.

Abstract: By accurately estimating the survival cell count in a probiotic product, the time for developing the product can be shortened. In a device (1) for estimating survival cell count, a calculation unit (14) calculates an estimated result of the survival cell count nt (CFU/g) of a specific strain contained in a composition after storage, in accordance with the following equation (I). (I) Log10nt=Log10n0?t×EXP{(AT×T+BT)w+(CT×T+DT)}, provided that t stands for the storage period (days)× 1/30, nt stands for the survival cell count (CFU/g) of the strain contained in the composition after the storage period t (days), n0 stands for the viable cell count (CFU/g) of the strain contained in the composition at the initiation of storage, T stands for the storage temperature (° C.), w stands for the water activity value of the composition, AT and CT stand for experimentally determined coefficients specific to the strain, and BT and DT stand for experimentally determined constants specific to the strain.

Abstract: The present invention relates to an agent for improving lipid metabolism, a food/drink, and a feed, containing ?s-casein as an active ingredient thereof. In addition, the present invention relates to an agent for suppressing body weight gain, an agent for reducing body fat, and an agent for reducing blood lipid, containing the agent for improving lipid metabolism.

Abstract: The present invention provides: an Aloe vera extract that can be safely ingested, can be used as a material of food for preventing lifestyle diseases, contains an extremely low level of an anthraquinone (anthraquinone-based compound), and can be added to foods; and a method of producing the Aloe vera extract. A supercritical fluid extraction method can produce an Aloe vera extract containing a mixture that consists of a cyclolanostane compound and a lophenol compound in an amount of 1.0% by mass or more and having the following properties (1) and/or (2): (1) the mass mixing ratio of the cyclolanostane compound and lophenol compound is as follows: cyclolanostane compound:lophenol compound=6.3:2.7 to 5.1:4.9; and/or (2) the content of an anthraquinone-based compound is 0.001% by mass or less.