Abstract: A method for detecting albumin based on a colorimetric assay and a system thereof are disclosed. Gold nanoparticles are added into the sample preparing device having a sample without spectroscopic tags, wherein the sample without spectroscopic tags is formed as the alkaline solution to avoid the interference substances adhering on the gold nanoparticles. The gold nanoparticles are concentrated by using the microfluidic concentrator with the circular ion exchange membrane by applying an external electric field across two electrodes. The image of the concentrated gold nanoparticles is captured by the image capturing device for measuring the saturation intensities of the image, wherein there is a relation between the saturation intensities and the concentration of the albumin in the sample without spectroscopic tags. The concentration of the albumin of the sample without spectroscopic tags is obtained by the relation and the measured saturation intensities.

Abstract: A double nut ball screw capable of sensing preload includes a screw rod, two nuts, a connection key, multiple balls, a deformable annular platform having a U-shaped cross section with a bottom wall portion and two sidewall portions integrally connected with two opposite lateral sides of the bottom wall portion, and an annular force sensor mounted on the bottom wall portion of the deformable annular platform and located between the two sidewall portions. The deformable annular platform has a protruded portion located at the outer surface of the bottom wall portion opposite to the force sensor, and is disposed in the gap between the two nuts and wedged between two mating surfaces of the two nuts with the distal ends of the sidewall portions abutted against the mating surface of one nut and the protruded portion abutted against the mating surface of the other nut.

Abstract: A cancerous lesion identifying method via hyper-spectral imaging technique comprises steps of: acquiring a plurality of first pathology images via an endoscopy, wherein the first pathology images are cancerous lesion images respectively; importing the first pathology images into an image processing module to acquire a plurality of first simulating spectra of the first pathology images so as to generate a principle component score diagram in accordance with the first simulating spectra; defining a plurality of triangle areas in the principle component score diagram in accordance with the first simulating spectra; determining whether a principle component score of a second simulating spectrum of a second pathology image is within any one of the triangle areas; and confirming the second pathology image belongs to one of the cancerous lesion images when the principle component score of the second simulating spectrum is within any one of the triangle areas.

Abstract: Disclosed is a microfluidic biosensing system including a processor, in which a Raman barcode database corresponding to at least one Raman spectrum signal is stored, a plurality of Raman barcode beads mixed with a target fluid and coupled to at least one target bioparticle in the target fluid, a microfluidic channel disposed to make the target fluid mixed with the Raman barcode beads flow therethrough, a light source disposed on the microfluidic channel, and a spectral detection device connected to the processor and disposed to correspond to the light source. The spectral detection device receives the Raman spectrum signal generated when the target bioparticle coupled with the Raman barcode bead is irradiated, and transfers the received Raman spectrum signal to the processor. The processor determines a type of the bioparticle(s) and calculates the number of bioparticle(s) by matching the Raman spectrum signal(s) to the Raman barcode database.

Abstract: A modular transmission line device includes a power input module, a transmission line module, a load module and a plurality of LED modules. The power input module, the transmission line module and the load module are sequentially electrically connected and assembled. The power input module transmits an AC voltage to the transmission line module and the load module. The AC voltage is used to generate an electromagnetic wave in the transmission line module according to a loading impedance of the load module and a characteristic impedance of the transmission line module. Each LED module is electrically connected with and assembled with the transmission line module. The LED modules radiates according to the electromagnetic wave.

Abstract: A device for detecting and correcting timing error and a method for designing typical-case timing using the same is disclosed. The device includes two datapath units connected with first and second multiplexers and two transition detectors. Each datapath unit receives and calculates an input signal to generate a speculation value and a correct value. Then, the speculation value and the correct value are transmitted to the first and second multiplexers and the transition detectors determine whether transition of the outputted speculation value is unstable. If yes, the datapath unit outputting the speculation value is stalled for a period of time for correction, whereby the second multiplexer outputs the correct value. If no, the datapath unit outputs the speculation value, then the present invention uses the undertaken timing as a setting specification to complete a circuit design. The present invention can improve system efficiency and power of the whole circuit.

Abstract: A method of manufacturing nitrone compounds is provided. The method includes: providing a nitro compound; and performing a photoreaction of the nitro compound, a catalyst and an additive under visible light to obtain the nitrone compound.

Abstract: A reflection-based tubular waveguide particle plasmon resonance sensing system and a sensing device thereof are provided. The sensing device includes a hollow tubular waveguide element having wall, a reflection layer disposed on one end of the wall (distal end), and a noble metal nanoparticle layer distributed on the surface of the wall. An incident light enters the wall through another end of the tubular waveguide element (proximal end) and being total internal reflected many times along the wall, then is reflected by the reflection layer and being total internal reflected many times along the wall again, and finally, the incident light exits the proximal end. Wherein, when the sample contacts the noble metal nanoparticle layer of the tubular waveguide element, the particle plasmon resonance condition is altered and hence the signal intensity of the light exiting the tubular waveguide element changes.

Abstract: A springless voice coil actuator is provided. The springless voice coil includes a base, a coil, a guiding rod, a slidable base, a main magnetic component and a balance magnetic component. The coil is disposed on the base. The guiding rod is disposed on the base. The slidable base is for sliding along the guiding rod to a predetermined direction. The main magnetic component is connected to the slidable base. The balance magnetic component is coupled with the main magnetic component for generating a magnetic induction.

Abstract: A method of making a calcium-fluoride layer formed on an object surface for more wear resistance includes the steps of coating sodium fluoride to a surface of an object having calcium, whereby the calcium fluoride and the calcium are inverted to become a calcium-fluoride layer on the surface of the object after a chemistry reaction; preparing a CO2 laser device having a CO2 laser emitter for emitting CO2 laser; and applying irradiation of the CO2 laser via the CO2 laser emitter to the calcium-fluoride layer for at least five seconds. In light of this, the wear resistance of the calcium-fluoride layer is enhanced for at least 34%, the absorption rate of the fluoride is increased for at least 23%, and the surface of the object has aesthetic and integral appearance.

Abstract: A method for obtaining the binding kinetic rate constants using fiber optic particle plasmon resonance (FOPPR) sensor, suitable for a test solution with two or more concentrations, which employs the following major steps: providing one FOPPR sensor instrument system, obtaining optical time-resolved signal intensities starting at the initial time to the steady state of the two or more regions, substituting the measured signal intensity values into the formula which is derived by using the pseudo-first order rate equation model. In addition, this method measures the temporal signal intensity evolution under static conditions as the samples are quickly loaded. As a result, unlike the conventional device where the sample is continuously infused, the method is able to measure the association and dissociation rate constants of which the upper bounds are not limited by the sample flow rate.

Abstract: A method of examining the purity of dendrimers is revealed. It comprises steps of measuring a light scattering intensity of a set of pure standards having a specific molecular weight with a static laser light scattering detector by use of flow injection polymer analysis; establishing a scaling relation by doing a regression of a ratio of the light scattering intensity per concentration (I/c) against molecular weight (M.W.); measuring the light scattering intensity of a dendrimer to be tested having the same unit and surface-modified functional group as the set of pure standards, and examining the purity of the dendrimer to be tested according to the scaling relation.

Abstract: A multiplex fiber optic biosensor including an optical fiber, a plurality of noble metal nanoparticle layers, a plurality of light sources and a light source function generator is disclosed. The optical fiber includes a plurality of sensing regions which are unclad regions of the optical fiber so that the fiber core is exposed, wherein the noble metal nanoparticle layers are set in each sensing regions. The light sources emit light with different wavelengths, and the noble metal nanoparticle layers absorb the lights with different wavelengths, respectively. The light sources emit the lights in different timing sequences or different carrier frequencies, wherein when the lights propagate along the optical fiber in accordance with the different timing sequences or the different carrier frequencies, a detection unit detects particle plasmon resonance signals produced by interactions between the different noble metal nanoparticle layers and the corresponding analytes.

Abstract: A ball screw capable of sensing a preload is formed of a nut having an internal thread surrounding an imaginary central axis, a screw inserted into the nut and having an external thread surrounding the imaginary central axis, and a plurality of balls are mounted between the internal and external threads in a way that the balls roll therebetween. A mounting hole having a mounting surface therein is formed in the nut. The mounting surface corresponds to the internal thread in a way that it is substantially perpendicular to the imaginary central axis. A force sensor is mounted to the mounting surface. The force sensor can directly sense the preload in real time, so it is uneasily adversely affected by any environmental factor to have more accurate sensing result relatively.

Abstract: A color degradation compensation method includes the steps as follows. Two images are captured by an image capturing device, wherein the two images have an overlapped area. A semi-Gaussian model is constructed. At least one position in the overlapped area is selected and color values of a plurality of points in the position on each of the two images are read, wherein the points of each image are corresponded to the same position in the overlapped area. A degradation standard deviation of the two color values is calculated by the semi-Gaussian model. The color values of the two images are calibrated to compensated color values through the semi-Gaussian model again in accordance with the degradation standard deviation.

Abstract: An all-digital spread spectrum clock generating circuit with EMI reduction effect and a method for controlling the same utilize a digital spread-spectrum clock controlling unit to control a digital controlled oscillator, so that it can directly modulates an output clock frequency. Accordingly, the spectrum of the output clock frequency is spread, and the EMI effect due to the output clock signal is reduced. A spread-spectrum clock controller receives a reference clock counting signal and a dividing clock counting signal generated by a frequency detecting unit. After detecting and judging, the spread-spectrum clock controlling unit modulates and maintains a central frequency of the spread-spectrum clock periodically according to the two counting signals, thereby keeping a stability of the central frequency of the spread-spectrum clock signal and decreasing the complexity of the circuit design.

Abstract: A method for fixing metal onto a surface of the substrate. The present method includes steps of: providing a substrate and a mercaptoalkylsilatrane compound; dissolving the mercaptoalkylsilatrane compound in a solvent; performing a condensation reaction of the substrate with and the dissolved mercaptoalkylsilatrane compound to complete the surface modification of the substrate; and performing a covalent bonding process to metal with the mercaptoalkylsilatrane compound already modified onto the surface of the substrate to fix the metal onto the surface of the substrate.

Abstract: A light-mixing flashlight has a body, three light-emitting diodes, three first reflectors, and three second reflectors. The body has a mounting surface formed in the body, a body opening opposite to the mounting surface, and three light recesses formed in an interior of the body. The light-emitting diodes are mounted in the light recesses, and are respectively a red light, a green light, and a blue light light-emitting diode. The first reflectors are formed as parabolic mirrors and are respectively mounted in the light recesses via a working angle. An opening of each first reflector faces toward the corresponding light-emitting diode. The second reflectors are formed as spherical mirrors, are mounted on the mounting surface, and respectively correspond in position to the first reflectors. Therefore, the light-mixing flashlight has an improved emitting efficiency.

Abstract: Provided are a system and a method for detecting a number of layers of few-layer graphene employing multispectral image reproduction process to provide rapid detection of numbers of layers of few-layer graphenes on transparent or non-transparent substrates. The application of the system and method in relevant industries expedites validation and/or verification of the number of layers of an FLG product and improves the quality control efficiency thereof.

Abstract: A single-inductor multi-output (SIMO) conversion device for enlarging load range is disclosed. The SIMO conversion device comprises a power stage comprising a first switch and a second switch and receiving a direct-current (DC) current. A DC voltage source inputs the DC current to an inductor by timing of the first and second switches. Each control output circuit has a third switch connected with the inductor in series to receive an immediate current. The control output circuit sends out an output voltage selectively by the third switch. A control stage circuit receives a plurality of feedback voltage signals and selectively controls the order of adjusting energy of the output voltages by order control signals. The present invention uses a current sensing circuit to obtain the immediate current and switches control signals to establish the best order thereof according to different loads.