Patents Assigned to National Taiwan University
  • Patent number: 11859176
    Abstract: A method for in vitro activation and/or expansion of immune cells is provided, including the steps of: a) providing magnetic particles having multi-protrusive surface modified with at least one type of immuno-inducing substance, in which each magnetic particle includes a copolymer core, a polymer layer, a magnetic substance layer, and a silicon-based layer from the inside to the outside; b) providing a cell solution including at least one type of immune cell in the cell solution; and c) bringing the magnetic particles in contact with the cell solution, in which the at least one type of immuno-inducing substance on the surface of the magnetic particle activates and/or expands the at least one type of immune cell in the cell solution.
    Type: Grant
    Filed: December 21, 2018
    Date of Patent: January 2, 2024
    Assignees: Industrial Technology Research Institute, National Taiwan University Hospital
    Inventors: Cheng-Tai Chen, Chien-An Chen, Wen-Ting Chiang, Su-Feng Chiu, Pei-Shin Jiang, Jih-Luh Tang, Chien-Ting Lin, Xuan-Hui Lin
  • Patent number: 11864369
    Abstract: A device includes a first horizontal-gate-all-around (HGAA) transistor, a second HGAA transistor, a first vertical-gate-all-around (VGAA) transistor, and a second VGAA transistor. The first HGAA transistor and the second HGAA transistor are adjacent to each other. The first VGAA transistor is over the first HGAA transistor. The second VGAA transistor is over the second HGAA transistor. A top surface of the first VGAA transistor is substantially coplanar with a top surface of the second VGAA transistor.
    Type: Grant
    Filed: March 10, 2022
    Date of Patent: January 2, 2024
    Assignees: TAIWAN SEMICONDUCTOR MANUFACTURING CO., LTD., NATIONAL TAIWAN UNIVERSITY
    Inventors: Hung-Yu Ye, Chung-Yi Lin, Yun-Ju Pan, Chee-Wee Liu
  • Publication number: 20230422515
    Abstract: An integrated circuit device includes a substrate and a memory device. The memory device is over the substrate. The memory device includes a bottom electrode, a dielectric layer, an antiferroelectric layer, and a top electrode. The dielectric layer is over the bottom electrode. The antiferroelectric layer is over the dielectric layer. The top electrode is over the antiferroelectric layer.
    Type: Application
    Filed: June 24, 2022
    Publication date: December 28, 2023
    Applicants: TAIWAN SEMICONDUCTOR MANUFACTURING COMPANY, LTD., NATIONAL TAIWAN UNIVERSITY, National Taiwan Normal University
    Inventors: Kuo-Yu HSIANG, Chun-Yu LIAO, Jen-Ho LIU, Min-Hung LEE
  • Patent number: 11855171
    Abstract: A method includes forming source/drain regions in a semiconductor substrate; depositing a zirconium-containing oxide layer over a channel region in the semiconductor substrate and between the source/drain region; forming a titanium oxide layer in contact with the zirconium-containing oxide layer; forming a top electrode over the zirconium-containing oxide layer, wherein no annealing is performed after depositing the zirconium-containing oxide layer and prior to forming the top electrode.
    Type: Grant
    Filed: August 12, 2021
    Date of Patent: December 26, 2023
    Assignees: TAIWAN SEMICONDUCTOR MANUFACTURING CO., LTD., NATIONAL TAIWAN UNIVERSITY
    Inventors: Miin-Jang Chen, Sheng-Han Yi, Chen-Hsuan Lu
  • Patent number: 11856694
    Abstract: The disclosure provides a circuit substrate and a method for manufacturing the same. The circuit substrate includes a wiring and a substrate having a base region and a circuit region. The base region having a first pattern is constituted by a first thermoplastic material. The circuit region having a second pattern is constituted by a second thermoplastic material. The first pattern has a portion opposite to the second pattern. The wiring is formed on the circuit region along the second pattern. The first thermoplastic material is different from the second thermoplastic material, and the second thermoplastic material includes a catalyst particle.
    Type: Grant
    Filed: August 31, 2020
    Date of Patent: December 26, 2023
    Assignee: National Taiwan University of Science and Technology
    Inventors: Chen-Hao Wang, Hsueh-Yu Chen, Guan-Cheng Tong
  • Patent number: 11855099
    Abstract: A method includes forming a first dielectric layer over the substrate and covering first, second, third, fourth, fifth and sixth protrusion regions; forming first, second, and third gate conductors over the first, fourth, and fifth protrusion regions, respectively; performing a first implantation process to form a second source region and a second drain region in the fourth protrusion region; performing a second implantation process to form a first source region and a first drain region in the first protrusion region, and to form a third source region and a third drain region in the fifth protrusion region; forming a metal layer over the third protrusion region; patterning the metal layer to form an inner circular electrode and an outer ring electrode encircling the inner circular electrode; forming a word line; and forming a bit line.
    Type: Grant
    Filed: January 24, 2022
    Date of Patent: December 26, 2023
    Assignees: TAIWAN SEMICONDUCTOR MANUFACTURING COMPANY, LTD., NATIONAL TAIWAN UNIVERSITY
    Inventors: Jenn-Gwo Hwu, Ting-Hao Hsu
  • Patent number: 11855150
    Abstract: A device includes a substrate, a channel layer, a barrier layer, a gate electrode, and source/drain contacts. The channel layer is made of transition metal dichalcogenide. The barrier layer is over the channel layer. The gate electrode is over the barrier layer. The source/drain contacts are on opposite sides of the gate electrode and over the barrier layer.
    Type: Grant
    Filed: May 27, 2022
    Date of Patent: December 26, 2023
    Assignees: TAIWAN SEMICONDUCTOR MANUFACTURING CO., LTD., NATIONAL TAIWAN UNIVERSITY
    Inventors: Yun-Yuan Wang, Chih-Hsiang Hsiao, I-Chih Ni, Chih-I Wu
  • Patent number: 11851435
    Abstract: Disclosed are compounds of formula (I) as follows: in which each of R1, R2, R3, R4, R5, L1, W, and Het is defined herein. Also provides are a method of inhibiting prostaglandin reductase 2 (“PTGR2”) using such a compound and a pharmaceutical composition containing same.
    Type: Grant
    Filed: March 7, 2022
    Date of Patent: December 26, 2023
    Assignees: National Health Research Institutes, National Taiwan University
    Inventors: Lun Kelvin Tsou, Ming-Shiu Hung, Chieh Wen Chen, Meng-Lun Hsieh, Yi-Cheng Chang, Lee Ming Chuang
  • Patent number: 11855190
    Abstract: A method for forming a semiconductor device is provided. A first patterned mask is formed on the substrate, the first patterned mask having a first opening therein. A second patterned mask is formed on the substrate in the first opening, the first patterned mask and the second patterned mask forming a combined patterned mask. The combined patterned mask is formed having one or more second openings, wherein one or more unmasked portions of the substrate are exposed. Trenches that correspond to the one or more unmasked portions of the substrate are formed in the substrate in the one or more second openings.
    Type: Grant
    Filed: December 13, 2022
    Date of Patent: December 26, 2023
    Assignees: TAIWAN SEMICONDUCTOR MANUFACTURING COMPANY, COMPANY NATIONAL TAIWAN UNIVERSITY
    Inventors: Miin-Jang Chen, Kuen-Yu Tsai, Chee-Wee Liu
  • Patent number: 11848628
    Abstract: A flexible clean energy power generation device with high power efficiency, which is a multi-film structure, includes an internal conductive support layer and an ion transport layer. The internal conductive support layer is formed by coating a conductive material onto a hydrophilic substrate; the ion transport layer is formed by coating a polyelectrolyte onto an outer side of the internal conductive support layer. After a solution is dropped on the device, the solution produces a capillary pressure difference by capillary action and evaporation phenomena to drive water molecules and counterions of the solution to move from a wet side to a dry side, thus producing a potential difference. Without an external pressure, the device uses a layered two-dimensional conductive material together with a polyelectrolyte, realizing a self-electrokinetic power generation with high energy output and long-life by capillary action and evaporation phenomena with using pure aqueous solution or other electrolyte solutions.
    Type: Grant
    Filed: August 25, 2021
    Date of Patent: December 19, 2023
    Assignee: NATIONAL TAIWAN UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Li-Hsien Yeh, Mengyao Gao, Jie-Yu Yang
  • Patent number: 11846972
    Abstract: A method and an apparatus for generating software test reports are provided. The method includes following steps: providing a testing platform that supports retrieving one or more documents such as screenshots or DOM-like documents related to screen content of an application under test (AuT) and analyzing the documents to obtain description data of the screen content; selecting to execute a test report generator, and querying the description data, multiple test scripts ever executed on a system under test (SuT) and multiple test actionables from the testing platform by the test report generator, so as to evaluate a test trace of the AuT, calculate at least one test actionable and test data adapted for the AuT, and return the calculated test actionable to the testing platform; and executing the test actionable on the AuT in the SuT by the testing platform, so as to generate test reports of the AuT.
    Type: Grant
    Filed: April 11, 2022
    Date of Patent: December 19, 2023
    Assignee: National Taiwan University
    Inventor: Farn Wang
  • Patent number: 11848444
    Abstract: A preparation method of a positive electrode material of a lithium battery is provided, including mixing a compound containing at least one ethylenically-unsaturated group and one carbonyl group or a derivative thereof and a Ni-rich oxide of lithium and transition metal to react. The compound containing at least one ethylenically-unsaturated group and one carbonyl group is selected from a group consisting of a maleimide-based compound, an acrylate-based compound, a methacrylate-based compound, an acrylamide-based compound, a vinylamide-based compound, and a combination thereof, and the Ni-rich oxide of lithium and transition metal is represented by formula I, LiNixMyO2 ??Formula I wherein x+y=1, 1>x?0.5, and M is at least one transition metal element except Ni.
    Type: Grant
    Filed: March 13, 2020
    Date of Patent: December 19, 2023
    Assignee: National Taiwan University of Science and Technology
    Inventors: Fu-Ming Wang, Nan-Hung Yeh, Laurien Merinda, Xing-Chun Wang
  • Publication number: 20230398142
    Abstract: Provided is a method for preventing or treating urological chronic pelvic pain syndrome (UCPPS) in a subject that includes administering an effective amount of cerium oxide nanoparticles (CeNPs) to the subject. Also provided is a method for preventing or treating an UCPPS in a subject that includes administering to the subject a pharmaceutical composition comprising an effective amount of the CeNPs and a pharmaceutically acceptable carrier thereof.
    Type: Application
    Filed: June 8, 2022
    Publication date: December 14, 2023
    Applicants: National Health Research Institutes, National Taiwan University, National Chung Hsing University, National Cheng Kung University
    Inventors: Wei-Chih LIEN, Feng-Huei Lin, Hui-Min Wang, Tak Shing Ching, Xin-Ran Zhou, Ya-Jyun Liang, Chia-Yih Wang, Fu-I Lu, Huei-Cih Chang
  • Publication number: 20230402921
    Abstract: An adjustable voltage regulator circuit, including a voltage conversion circuit, a voltage conversion controller, and a clock generator, is provided. The voltage conversion circuit receives an input voltage to generate an output voltage. The voltage conversion controller detects the output voltage, compares the output voltage with a reference voltage value, and outputs an enable signal based on a comparison result to control the voltage conversion circuit to adjust the output voltage. The clock generator generates a first clock signal and a second clock signal to respectively drive the voltage conversion circuit and the voltage conversion controller. The voltage conversion controller adjusts the enable signal to gradually adjust the output voltage to a predetermined voltage range.
    Type: Application
    Filed: June 13, 2022
    Publication date: December 14, 2023
    Applicant: National Taiwan University
    Inventors: Bing-Chen Wu, Tsung-Te Liu
  • Patent number: 11840729
    Abstract: A portable genome sequencing and genotyping device includes a sample processing module, a sequencing module, an analyzing module, and a communication module. The sample processing module is configured to process a sample so as to generate at least one DNA segment of the sample. The sequencing module is connected to the sample processing module, and is configured to generate a number of base sequences corresponding to the at least one DNA segment. The analyzing module is coupled to the sequencing module, and is configured to generate a genotyping analysis result based on the base sequences. The communication module is configured to receive the genotyping analysis result and transmit the genotyping analysis result to a user terminal.
    Type: Grant
    Filed: December 7, 2020
    Date of Patent: December 12, 2023
    Assignees: NATIONAL CHIAO TUNG UNIVERSITY, NATIONAL TAIWAN UNIVERSITY
    Inventors: Jui-Hung Hung, Chia-Hsiang Yang
  • Patent number: 11839452
    Abstract: A non-contact blood pressure measurement system and a non-contact blood pressure value calculation method thereof are disclosed. The non-contact blood pressure measurement system includes a measurement module, a signal processing module, and a calculation module. The measurement module measures a physiological signal of a subject being tested in a non-contact manner. The signal processing module is used to obtain a forward pressure wave and a backward pressure wave according to the physiological signal of the subject being tested. The calculation module is used to find out a reflected pulse transit time between the forward pressure wave and the backward pressure wave so as to substitute the reflected pulse transit time and a plurality of correction parameters into a blood pressure algorithm formula to calculate an estimated diastolic blood pressure and an estimated systolic blood pressure of the subject being tested.
    Type: Grant
    Filed: May 20, 2021
    Date of Patent: December 12, 2023
    Assignee: NATIONAL TAIWAN UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Chao-Hsiung Tseng, Tzu-Jung Tseng
  • Publication number: 20230395379
    Abstract: A method of forming a semiconductor device includes forming a semiconductor strip extending above a semiconductor substrate, forming shallow trench isolation (STI) regions on opposite sides of the semiconductor strip, recessing a portion of the semiconductor strip, etching the STI regions to form a recess in the STI regions, forming a first thermal conductive layer in the recess, forming a source/drain epitaxy structure on the first thermal conductive layer, and forming a gate stack across the semiconductor strip and extending over the STI regions.
    Type: Application
    Filed: June 7, 2022
    Publication date: December 7, 2023
    Applicants: TAIWAN SEMICONDUCTOR MANUFACTURING COMPANY, LTD., NATIONAL TAIWAN UNIVERSITY
    Inventors: Chia-Che CHUNG, Chia-Jung TSEN, Chee-Wee LIU
  • Publication number: 20230397501
    Abstract: A method of forming a memory device including forming a bottom electrode via (BEVA) in a dielectric layer, forming a magnetic tunnel junction (MTJ) multilayer structure over the BEVA, forming a top electrode on the MTJ multilayer structure, patterning the MTJ multilayer structure using the top electrode as an etch mask to form a MTJ stack, forming a first interlayer dielectric (ILD) layer over the MTJ stack, and after forming the first ILD layer, forming a ferromagnetic metal that exerts a magnetic field on the MTJ stack.
    Type: Application
    Filed: June 2, 2022
    Publication date: December 7, 2023
    Applicants: TAIWAN SEMICONDUCTOR MANUFACTURING COMPANY, LTD., NATIONAL TAIWAN UNIVERSITY
    Inventors: Ya-Jui TSOU, Jih-Chao CHIU, Huan-Chi SHIH, Chee-Wee LIU, Shao-Yu LIN, Chih-Lin WANG
  • Publication number: 20230395693
    Abstract: A method includes forming a semiconductor structure on a substrate; performing a first etching process on the semiconductor structure to form a fin structure upwardly extending above the substrate; performing a second etching process to trim the fin structure to have a reverse-trapezoidal cross-sectional profile; forming source/drain regions on opposite regions of the fin structure; forming a gate structure between the source/drain regions.
    Type: Application
    Filed: June 1, 2022
    Publication date: December 7, 2023
    Applicants: TAIWAN SEMICONDUCTOR MANUFACTURING COMPANY, LTD., NATIONAL TAIWAN UNIVERSITY
    Inventors: Chien-Te TU, Chee-Wee LIU
  • Publication number: 20230395725
    Abstract: A method includes forming a fin over a substrate, the fin comprising alternately stacking first oxide-based semiconductor layers and second oxide-based semiconductor layers, removing the second oxide-based semiconductor layers to form a plurality of spaces each between corresponding ones of the first oxide-based semiconductor layers, and depositing in sequence a gate dielectric layer and a gate metal into the plurality of spaces each between corresponding ones of the second oxide-based semiconductor layers.
    Type: Application
    Filed: June 1, 2022
    Publication date: December 7, 2023
    Applicants: TAIWAN SEMICONDUCTOR MANUFACTURING COMPANY, LTD., NATIONAL TAIWAN UNIVERSITY
    Inventors: Jih-Chao CHIU, Song-Ling LI, Chee-Wee LIU