Abstract: Provided is a material for preventing bone cement from leaking out from bone during packing of the bone cement into a bone fracture site. The bone cement can be prevented from leaking out from the bone by employing a three-dimensional structure produced from a material containing a polyhydroxyalkanoate, when packing the bone cement into the bone fracture site.

Abstract: A micromachining method, a die manufacturing method, and a micromachining apparatus performing accurate micromachining on a surface of a workpiece at high speed. A micromachining apparatus having a cutting tool and a vibration unit for vibrating the cutting tool in a first direction is used. The angle formed between an average cutting direction of the cutting tool and the first direction is set to fall within a range of 20° to 120°. Recesses and protrusions are formed on a surface of a workpiece as a result of machining by the cutting tool which is vibrating in the first direction.

Abstract: In a load sensor detecting a magnitude of an external load applied in a direction parallel to a sheet shape of a sheet-shaped quartz crystal resonator, the load sensor comprising: a quartz crystal resonator layer including the sheet-shaped quartz crystal resonator and a pair of electrode portions on a pair of surfaces opposite to each other in a plate thickness direction of the quartz crystal resonator; and a pair of holding layers disposed to sandwich both sides of the sheet shape of the quartz crystal resonator layer and causing a displacement in substantially the same amount as the quartz crystal resonator layer when the external load is applied to the quartz crystal resonator layer, the holding layers and the quartz crystal resonator layer are made of materials having substantially equivalent rates of thermal expansion.

Abstract: Provided are a communication control device and a communication system capable of detecting message transmission in the case where an invalid device transmits a message to a common communication line. A monitoring device decides a reference time point t0 for periodical message transmission by an ECU, decides multiple scheduled transmission time points t1, t2, . . . obtained by adding a period corresponding to an integer multiple of a transmission cycle T of a message to the reference time point t0, and decides that a predetermined period including each of the scheduled transmission time points is a permission period for message transmission. The monitoring device determines whether or not a detected message on a CAN bus has been transmitted during the permission period. If determined that transmission of an invalid message is not permitted, the monitoring device performs processing of causing the ECU which receives the message to discard the message.

Abstract: The present invention addresses the problem of providing a novel use of pluripotent stem cells (Muse cells) for medical purposes in regenerative medicine. The present invention provides a cell preparation and a pharmaceutical composition both for ameliorating and treating perinatal brain damage including learning disability and motor disability, each of the cell preparation and the pharmaceutical composition containing SSEA-3-positive pluripotent stem cells isolated from a mesenchymal tissue collected from a living body or cultured mesenchymal cells. The cell preparation according to the present invention relies on a mechanism that Muse cells are administered to a subject having the above-mentioned damage to cause the engraftment of the Muse cells in a damaged brain tissue, thereby ameliorating and treating the damage.

Abstract: Provided is a method, a device and a kit for detecting childhood cancer, predicting the risk of childhood cancer, determining the stage of the childhood cancer, determining the prognosis of the childhood cancer, and/or monitoring the effect of a treatment for the childhood cancer in a subject by measuring ae urinary metabolite of the subject.

Abstract: A communication device capable of detecting transmission of an improper message to a network. A CAN controller in the gateway transmits and receives a message attached with a priority level (ID) to/from an ECU through a communication line, and counts, by the consecutive block number counter, the number of transmitted messages that are consecutively blocked as a result of arbitration processing as the number of consecutive blocks and stores the number as the number of allowed blocks into an allowed block number table in the storage unit in association with a priority level attached to the message received at the communication line. Every time a message is received, the controller compares the number of consecutive blocks with the number of allowed blocks for this message, and detects abnormality if the number of consecutive blocks is larger than the number of allowed blocks.

Abstract: Provided are a knockout mouse, a method for screening a substance for suppressing mesial temporal lobe epilepsy, and a method for selecting a technique for suppressing mesial temporal lobe epilepsy. A knockout mouse 30 or more days of age that has lost the function of the Girdin gene in at least the nervous tissues and exhibits the phenotypes of (1), (2), and (3) below. (1) hippocampal sclerosis should be present, (2) extrahippocampal brain damage should be limited, and (3) spontaneous epilepsy that can be said to be of hippocampal origin should be present.

Abstract: The present invention aims at providing a novel indocyanine compound solving problems of conventionally used indocyanine green, such as solubility in water or physiological saline, a synthesis method and a purification method thereof, and a diagnostic composition including the novel indocyanine compound. Further, provided are a method for evaluating biokinetics of the novel indocyanine compound and a device for measuring biokinetics, and a method and a device for visualizing circulation of fluid such as blood in a living body, which utilize the diagnostic composition. Also, found are a novel indocyanine compound in which a hydrophobic moiety in a near-infrared fluorescent indocyanine molecule is included in a cavity of a cyclic sugar chain cyclodextrin to cover the hydrophobic moiety in the indocyanine molecule with the glucose, and a synthesis method and a purification method thereof.

Abstract: Provided are a communication device and a communication restriction program capable of suppressing invalid message transmission to a network by injecting an invalid program. The ECU includes a CAN controller having a register group storing a value concerning communication with a different ECU and a processing unit processing a value for the register group. The ECU switches the mode between the full control mode in which writing and reading are allowed for the register group in the CAN controller and the restriction mode wherein writing and reading are restricted for a part of the registers in the register group. The ECU sets a predetermined period from activation corresponding to the full control mode, and switches the full control mode to the restriction mode after the predetermined period elapses. After switching to the restriction mode, the ECU will not switch the mode to the full control mode.

Abstract: A carbon isotope analyzer 1 includes a carbon dioxide isotope generator 40 that includes a combustion unit that generates gas containing carbon dioxide isotope from carbon isotope, and a carbon dioxide isotope purifying unit; a spectrometer 10 including an optical resonator 11 having a pair of mirrors 12, and a photodetector 15 that determines the intensity of light transmitted from the optical resonator 11; and a light generator 20 including a light source 23, a first optical fiber 21 to transmit a light beam from the light source 23, a second optical fiber 22 for wavelength conversion, the second optical fiber 22 splitting from the first optical fiber 21 at a point and combining with the first optical fiber 21 at another point downstream of the splitting point, and a non-linear optical crystal 25 that generates light having the absorption wavelength of the carbon dioxide isotope on the basis of the difference in frequency between light beams transmitted through the optical crystal 25.

Abstract: Electrons excited by irradiation of a visible light to a sample is at an energy level lower than a vacuum level, thus photoelectrons are not emitted from the sample and energy of excited electrons cannot be measured. The visible light is irradiated to the sample through a mesh electrode. A surface film for reducing the vacuum level is formed on a surface of the sample. With the surface film being formed, photoelectrons are obtained by the visible light, and these photoelectrons are accelerated by the mesh electrode toward a photoelectron spectrometer. Ultraviolet light may be irradiated to the sample and metal having same potential therewith. In this case, the mesh electrode is set at a retracted position to prohibit interaction of the mesh electrode and the ultraviolet light. A difference between the valence band and the Fermi level of the sample can be measured.

Abstract: The purpose of the present invention is to provide a novel medical use of pluripotent stem cells (Muse cells) in the regenerative medicine area. Provided are a cell preparation and a medicinal composition for ameliorating and treating chronic lung disease in newborns, said cell preparation and medicinal composition comprising SSEA-3-positive pluripotent stem cells isolated from a mesenchymal tissue in a living body or cultured mesenchymal cells. The cell preparation according to the present invention is based on a mechanism whereby the aforesaid disease is ameliorated and treated by administering Muse cells to a subject suffering from the disease and engrafting the cells in lung tissues.

Abstract: The purpose of the present invention is to identify a migratory factor that guides pluripotent stem cells (Muse cells) useful in new medical applications to damage, and to provide a pharmaceutical composition that includes the migratory factor for promoting tissue regeneration in regenerative medicine that makes use of Muse cells. In the present invention, a receptor that is specifically expressed in Muse cells rather than non-Muse cells was identified, and it was confirmed that a ligand for this receptor can function as a migratory factor. In the present invention, sphingosine-1-phosphate (S1P) was identified as a migratory factor, and thus, the present invention pertains to a pharmaceutical composition for guiding pluripotent stem cells to damage, the composition including S1P as an active ingredient.

Abstract: A phosphor is represented by the general formula aMIX·MII1-xMIMVO4:(Re)x where MI is at least one atomic element selected from the group consisting of K, Li, Na, Rb, Cs, Fr, Cu, and Ag, with K being essential; MII is at least one atomic element selected from the group consisting of Mg, Ca, Sr, Ba, Ra, Mn, Zn, Cd, and Sn; MV is at least one atomic element selected from the group consisting of P, V, Nb, Ta, As, Sb, and Bi; X is at least one halogen element, with F being essential; Re is at least one atomic element selected from the group consisting of rare earth elements, with Eu being essential; and a is in the range 0.6?a?1.4.

Abstract: The present invention aims at providing a novel indocyanine compound solving problems of conventionally used indocyanine green, such as solubility in water or physiological saline, a synthesis method and a purification method thereof, and a diagnostic composition including the novel indocyanine compound. Further, provided are a method for evaluating biokinetics of the novel indocyanine compound and a device for measuring biokinetics, and a method and a device for visualizing circulation of fluid such as blood in a living body, which utilize the diagnostic composition. Also, found are a novel indocyanine compound in which a hydrophobic moiety in a near-infrared fluorescent indocyanine molecule is included in a cavity of a cyclic sugar chain cyclodextrin to cover the hydrophobic moiety in the indocyanine molecule with the glucose, and a synthesis method and a purification method thereof.

Abstract: A second-time collision position estimator section estimates a second-time collision position that is a position at which an occupant on a two-wheel mobile object has a second-time collision, based on a relative vector estimated by a relative vector estimator section and a first-time collision position identified by a first-time collision position identifier section. An operation instructor section operates an external protection device, which is determined to be able to protect the occupant on the two-wheel mobile object based on the second-time collision position estimated by the second-time collision position estimator section.

Abstract: A driving assistance device includes a driving situation acquisition unit that acquires driving situations of vehicles that may collide with each other, a driving characteristics acquisition unit that acquires driving characteristics of drivers of the vehicles, a driving action determination unit that determines driving actions that allow the vehicles to avoid collision with each other in the driving situation acquired by the driving situation acquisition unit and that match the driving characteristics acquired by the driving characteristics acquisition unit, and a driving action instruction unit that instructs the vehicles about the driving actions determined by the driving action determination unit.

Abstract: In an on-vehicle system, on-vehicle device and gateway are connected via a first network, and the gateway and relay are connected via a second network. The relay performs open-close control of a gate, using a TAS standard of Ethernet TSN. The gateway receives first and second packets including given data, generates a third packet including the first and second packets, and sends the third packets at the transmission timing that is a timing the gate is placed in from closed state to open state to the relay. The relay receives the third packet from the gateway. The relay switches timing to transfer data, for each type of data, and transfer the third packet to the other relay, during a period in which the gate for the type of data is in an open state.

Abstract: Disclosed is a method comprising acquiring a value relating to VEGF-A of a subject, wherein the value is a measured value of total VEGF-A in a blood sample, or a value obtained by dividing a measured value of VEGF-A165b in the blood sample by a measured value of total VEGF-A in the blood sample (VEGF-A165b/total VEGF-A), and the value suggests prognosis of myocardial infarction of the subject or severity of coronary artery disease of the subject.