Patents Assigned to Old Dominion University Research Foundation
  • Publication number: 20110311639
    Abstract: Described is a direct method for the fabrication of resorcinarene nanocapsules by photopolymerization of compounds of formula (I), such as resorcinarene tetraalkene tetrathiol (RTATT), in the absence of any template or preorganization. Further, by varying the polymerization media, a variety of other polymeric architectures like lattices, fibrous networks, and nanoparticles were obtained. The morphology and structure were characterized by transmission electron microscopy, energy dispersive spectroscopy, scanning electron microscopy, dynamic light scattering, infrared and nuclear magnetic resonance spectroscopy. These morphologically distinct resorcinarene polymeric architectures contain residual thiol and ene functional groups offering potential functionalization opportunities.
    Type: Application
    Filed: June 21, 2011
    Publication date: December 22, 2011
    Applicant: Old Dominion University Research Foundation
    Inventors: Ramjee Balasubramanian, Zaharoula M. Kalaitzis, Srujana Prayakarao
  • Patent number: 8080679
    Abstract: Disclosed is the direct conversion process for producing biodiesel from a biomass. The direct conversion process for producing biodiesel from a biomass comprises reacting a feed stock comprising a biomass and an alkylation reagent in a substantially oxygen free environment at a temperature sufficient to hydrolyze one or more lipid glycerides in the biomass and alkylated one or more fatty acids in the reaction. The process may comprise reacting a feed stock comprising an algal biomass and tetramethylammonium hydroxide in a substantially oxygen free environment at a temperature between 250° C. and 500° C. The direct conversion process for producing biodiesel may further comprise reacting oil containing lipid glycerides with an alkylation reagent at a sufficient temperature to esterify the oil. The fatty acid alkyl esters produced from the reacted feed stock are recovered. The recovered fatty acid alkyl esters, as an essential component of biodiesel, may be formulated into biodiesel.
    Type: Grant
    Filed: December 17, 2008
    Date of Patent: December 20, 2011
    Assignee: Old Dominion University Research Foundation
    Inventors: Patrick G. Hatcher, Zhanfei Liu
  • Publication number: 20110306962
    Abstract: A method and device for treating a condition aggravated by the presence of amyloid fibrils is disclosed. The method includes applying a plurality of ultra-short pulses to target tissue comprising amyloid fibrils. The plurality of ultra-short pulses produce an electric field in the target tissue sufficient to change a molecular structure of the amyloid fibrils without causing the death, destruction, or serious injury of healthy cells surrounding the target tissue. For example, the plurality of ultra-short pulses can be sufficient to change the molecular structure of amyloid fibrils without causing apoptosis or necrosis of surrounding cells. The ultra-short pulses can be applied using an electrode device or a wideband antenna. The ultra-short pulses can have a duration ranging from 1 ps to 10 ns, an amplitude ranging from 100 V to 1 MV, and can apply an electrical field to the target tissue ranging from 1 kV/cm to 1 MV/cm.
    Type: Application
    Filed: June 15, 2011
    Publication date: December 15, 2011
    Applicant: OLD DOMINION UNIVERSITY RESEARCH FOUNDATION
    Inventors: Karl H. Schoenbach, Lesley Greene
  • Publication number: 20110292208
    Abstract: A method, system, and computer readable medium for producing orthoimages of the images of a (typically) high-resolution imager of an urban area, the orthoimages of high buildings being imaged with improved accuracy by increasing constraint conditions on the building edges, such as perpendicularity, collinearity. These constraint conditions are merged into an orthorectification model for orthorectifying the images captured at a predetermined elevation, whether by airborne or spaceborne. Constraint conditions may be formed by the building edge points, such as corners, and may be used with a digital building model. Thus, an aspect of embodiments is that the constraint conditions may be directly formed from the building themselves. The higher the buildings, the more effective the constraint controls.
    Type: Application
    Filed: November 23, 2010
    Publication date: December 1, 2011
    Applicant: Old Dominion University Research Foundation
    Inventors: Guoqing Zhou, Wenhan Xie
  • Publication number: 20110289830
    Abstract: Disclosed are processes for producing glycerol related products. One process comprises introducing a biomass and an alkylation reagent to a substantially oxygen free environment, hydrolyzing at a temperature at or above 200° C. one or more lipid glycerides in the biomass, methylating one or more fatty acids in the biomass with methyl groups from the alkylation reagent, wherein the hydrolyzing and methylating occur contemporaneously and separating resulting biodiesel and methylated glycerol-related products from a residue of the biomass by condensation.
    Type: Application
    Filed: August 8, 2011
    Publication date: December 1, 2011
    Applicant: OLD DOMINION UNIVERSITY RESEARCH FOUNDATION
    Inventors: Patrick G. Hatcher, Zhanfei Liu, Elodie Salmon
  • Publication number: 20110288545
    Abstract: Methods and devices designed to eliminate and/or ablate cancer or other abnormal growths of cells or tissues or eliminate and/or ablate cells or tissue with abnormal functions. In particular, using sub-microsecond electric pulses to treat cancer cells by, inter alia, inducing programmed cell death or other type of cell death. These methods and devices are expected to greatly improve the prevention, treatment and management of cancer by increasing the effectiveness of cancer treatments and development of resistance to new cancer growth.
    Type: Application
    Filed: April 22, 2011
    Publication date: November 24, 2011
    Applicant: OLD DOMINION UNIVERSITY RESEARCH FOUNDATION
    Inventors: Stephen J. Beebe, Xinhua Chen, Karl H. Schoenbach
  • Patent number: 8000813
    Abstract: Method and apparatus for cellular and intracellular manipulation of cell functions with ultrashort electrical pulses and for targeted delivery of the electrical pulses into cell cultures, patients, and tissues.
    Type: Grant
    Filed: August 21, 2006
    Date of Patent: August 16, 2011
    Assignee: Old Dominion University Research Foundation
    Inventors: Karl H. Schoenbach, Stephen Beebe
  • Publication number: 20110184411
    Abstract: A pectus bar extraction tool for removing a pectus bar having posterior and anterior sides includes a handle, an engagement member fixed to and extending from the handle for extending from the anterior to the posterior sides of the pectus bar to engage the posterior side of the pectus bar, and a lever arm fixed to and extending from the handle opposite to the engagement member for engaging the pectus bar on the anterior side of the pectus bar. A system and method for removing a pectus bar are also disclosed.
    Type: Application
    Filed: January 22, 2010
    Publication date: July 28, 2011
    Applicants: Old Dominion University Research Foundation, Children's Surgical Specialty Group, Inc.
    Inventors: Frederic McKenzie, Sebastian Bawab, Krzysztof Rechowicz, Robert Obermeyer
  • Publication number: 20110003350
    Abstract: A method and device for aggregating algae in an aqueous solution is disclosed. The method can include providing an algae feed comprising a liquid and algae dispersed therein. The algae feed can be aggregated by applying a nanosecond pulsed electric field to the algae feed. The nanosecond pulsed electric field can include a plurality of electric pulses having a pulse duration ranging from 1 to 1,000 nanoseconds. The method can also include separating an aggregated algae stream from the algae feed and feeding the aggregated algae stream to a lipid extraction operation.
    Type: Application
    Filed: June 25, 2010
    Publication date: January 6, 2011
    Applicant: Old Dominion University Research Foundation
    Inventors: Gary C. Schafran, Juergen F. Kolb, Aron Stubbins, Karl H. Schoenbach
  • Patent number: 7855513
    Abstract: A plasma reactor is provided, which includes a discharge chamber with dimensional characteristics and configuration of dielectric and electrodes so as to enhance efficiency based on the characteristics of the corona discharge streamers generated. Upon application of a pulsed high voltage potential, the discharge chamber enables formation of plasma where surface streamers play a greater role in the overall energy density of the discharge chamber than gas streamers. The formation of gas streamers is constrained. Because surface streamers have a higher energy density, the present invention is able to achieve improved energy efficiency while preserving effectiveness for gas treatment.
    Type: Grant
    Filed: October 5, 2007
    Date of Patent: December 21, 2010
    Assignee: Old Dominion University Research Foundation
    Inventors: Muhammed Arif Malik, Karl H. Schoenbach
  • Publication number: 20100286573
    Abstract: A method of inducing local hyperthermia in patient tissue is provided. The method includes generating ultra-wide-band radiation, conveying the ultra-wideband radiation to a focusing element, and focusing the ultra-wideband radiation on a target with the focusing element. A system for inducing local hyperthermia in patient tissue is also provided. The system includes a power source for generating ultra-wideband radiation, and a focusing element for focusing the ultra-wideband radiation on a target.
    Type: Application
    Filed: October 3, 2008
    Publication date: November 11, 2010
    Applicant: Old Dominion University Research Foundation
    Inventor: Karl H. Schoenbach
  • Publication number: 20100280513
    Abstract: A pulse delivery system for producing a spark in tissue is disclosed. The system can include at least two electrodes having sharp surface features, where the at least two electrodes are electrically isolated from one another. The sharp features of the electrodes can be separated by a distance of about 2 to 20 mm. The system can also include a pulse generator for delivering pulsed voltage differences between the at least two electrodes. The pulsed voltage differences can producing a voltage difference ranging from about 2.5 kV to about 35 kV for a duration of about 50 ns to 3 ?s. The system can include a controller for determining whether the plurality of pulsed voltage differences produced a spark between the at least two electrodes. A method of producing a spark in tissue for both therapeutic and cosmetic, i.e., non-therapeutic, applications is also disclosed.
    Type: Application
    Filed: April 14, 2010
    Publication date: November 4, 2010
    Applicant: Old Dominion University Research Foundation
    Inventors: Kolb F. Juergen, Scully Noah, Schoenbach H. Karl, Paithankar Dilip
  • Publication number: 20100278401
    Abstract: An imaging and recordation system is provided. The system includes a high-power, focusing antenna for illuminating biological tissue. The system further includes a power source for powering the antenna. The system further includes a data acquisition module, for recording the dielectric properties of tissues illuminated by the high-power, focusing antenna. The system illuminates the tissues using ultrashort electrical pulses.
    Type: Application
    Filed: December 19, 2008
    Publication date: November 4, 2010
    Applicant: Old Dominion University Research Foundation
    Inventors: Karl H. Schoenbach, Shu Xiao
  • Publication number: 20100211331
    Abstract: A system for measuring normal load and deflection of a material that includes a portable load deflection device and a method of using the same is disclosed. The system includes a support arm having a first end and a second end opposite said first end. The first end can be attached to a base surface. The support arm can provides at least three degrees of freedom of movement and includes at least one sensor for determining a position of the second end. A uniaxial load cell can be operably attached to the second end. The system can also include a processing system operable to receive position data and corresponding force data when the support arm is used to apply a non-normal compression force to the test surface. The data can be used to calculate normal force versus deflection data for the test surface.
    Type: Application
    Filed: February 17, 2010
    Publication date: August 19, 2010
    Applicant: Old Dominion University Research Foundation
    Inventors: Sebastian Bawab, Stacie Ringleb, Manish G. Kalmegh
  • Publication number: 20100031561
    Abstract: A raceway for cultivating algae in a liquid medium, comprising one or more precipitators positioned along the raceway, and at which precipitators the algal biomass produced in the raceway is precipitated from the liquid medium and concentrated.
    Type: Application
    Filed: July 10, 2009
    Publication date: February 11, 2010
    Applicant: OLD DOMINION UNIVERSITY RESEARCH FOUNDATION
    Inventors: Patrick G. Hatcher, Aron Stubbins, Elodie Salmon
  • Publication number: 20090158638
    Abstract: Disclosed is the direct conversion process for producing biodiesel from a biomass. The direct conversion process for producing biodiesel from a biomass comprises reacting a feed stock comprising a biomass and an alkylation reagent in a substantially oxygen free environment at a temperature sufficient to hydrolyze one or more lipid glycerides in the biomass and alkylated one or more fatty acids in the reaction. The process may comprise reacting a feed stock comprising an algal biomass and tetramethylammonium hydroxide in a substantially oxygen free environment at a temperature between 250° C. and 500° C. The direct conversion process for producing biodiesel may further comprise reacting oil containing lipid glycerides with an alkylation reagent at a sufficient temperature to esterify the oil. The fatty acid alkyl esters produced from the reacted feed stock are recovered. The recovered fatty acid alkyl esters, as an essential component of biodiesel, may be formulated into biodiesel.
    Type: Application
    Filed: December 17, 2008
    Publication date: June 25, 2009
    Applicants: OLD DOMINION UNIVERSITY, OLD DOMINION UNIVERSITY RESEARCH FOUNDATION
    Inventors: Patrick G. Hatcher, Zhanfei Liu
  • Patent number: 7362910
    Abstract: A method of characterizing and enhancing the pixels in an image, which is captured at all lighting conditions. The method enable dynamically enhancement of images captured at extremely low lighting conditions. Each pixel of the image, represented by I SUB (x, y) where x is the horizontal axis coordinate value and y is the vertical axis coordinate value, contains three color-components. Each pixel is characterized by defining a relationship between the three color-components of that pixel in its initial state. A nonlinear expansion function, which adaptively adjusts the expansion rate with respect to the statistical property of the original image, is used for enhancing the brightness of the image so that the poorly lighted pixels are enhanced in intensity more as compared to the amount of enhancement for the brighter pixels. The color property of each pixel in the enhanced image is then restored using the characteristic features previously defined by the relationship of the color components.
    Type: Grant
    Filed: January 21, 2005
    Date of Patent: April 22, 2008
    Assignee: Old Dominion University Research Foundation
    Inventors: Vijayan K. Asari, Ming-Jung Seow
  • Patent number: 7298092
    Abstract: A novel plasma reactor is provided that includes a discharge chamber with dimensional characteristics and configuration of dielectric and electrodes that optimize efficiency based on the characteristics of the corona discharge streamers generated. Upon application of a pulsed high voltage potential, the discharge chamber enables formation of plasma where surface streamers play a greater role in the overall energy density of the discharge chamber than gas streamers. The formation of gas streamers is constrained. Because surface streamers have a higher energy density, the present invention is able to achieve improved energy efficiency while preserving effectiveness for gas treatment.
    Type: Grant
    Filed: September 28, 2005
    Date of Patent: November 20, 2007
    Assignee: Old Dominion University Research Foundation
    Inventors: Muhammad Arif Malik, Karl J. Schoenbach
  • Patent number: 6858988
    Abstract: An electrodeless excimer UV lamp, comprising an enclosed chamber with a gas sealed within the enclosed chamber, wherein the gas is capable of being used to generate a plasma discharge, a first electrode wrapped around the outer surface of the chamber at a first location, a second electrode wrapped around the outer surface of the chamber at second location, and a power supply configured to apply a voltage to the first electrode and the second electrode. During operation of the UV lamp, a plasma discharge is generated by applying a voltage to the electrodes wrapped around the outer surface of the chamber to ignite the gas or gas mixture inside the chamber and generate a plasma discharge within the chamber, such that a specific wavelength of UV radiation will be generated by the particular gas within the chamber.
    Type: Grant
    Filed: October 30, 2002
    Date of Patent: February 22, 2005
    Assignee: Old Dominion University Research Foundation
    Inventor: Mounir Laroussi
  • Patent number: 6707556
    Abstract: A method and apparatus for determining the concentration of a constituent in a fluid by directing a beam of light into the fluid and sensing the intensity of components of the light emerging from the fluid at various wavelengths. The light emerging from the fluid can be light that has been attenuated by absorption or induced by fluorescent radiation. The effect of scattering on the light is minimized by normalizing the component intensities, which are then applied to an algorithm incorporating weighting factors that weighs the influence that the intensity at each wavelength has on the determination of the concentration of the constituent for which the algorithm was developed. The algorithm is developed by a regression analysis based upon a plurality of known mixtures containing various concentrations of the constituent of interest.
    Type: Grant
    Filed: September 19, 2002
    Date of Patent: March 16, 2004
    Assignees: APS Technology, Inc., Old Dominion University Research Foundation
    Inventors: William Edward Turner, Denis P. Biglin, Jr., John B. Cooper, Jeffrey F. Aust