Abstract: An embodiment of the invention is directed to a bone marrow aspiration device comprising a plurality of syringes, each of which operates in a series of sequential steps to obtain bone marrow of high quality and therapeutic value, i.e., having a high MSC/ml number. An embodiment of the invention preferably comprises three syringes, wherein a first syringe is used to aspirate bone marrow from a subject, a second syringe contains an anticoagulant, and the third syringe contains a mixture of the bone marrow aspirate and the anticoagulant.

Abstract: An apparatus and method is provided relating to artificial discs. An artificial disc is provided that facilitates simultaneous and independent articulation of flexion/extension, lateral bending, anterior/posterior translation, and axial rotation. The artificial disc provides these four simultaneous and independent articulations by independently addressing each type of articulation in the design of the artificial disc. In one example, an artificial disc is comprised of a bearing disposed between first and second end plates. The bearing is movable relative to each end plate, independent of the other end plate. The end plates are affixed to adjacent vertebrae.

Abstract: The invention is directed to an anchor for fixing a tendon or a ligament in a bone comprising: an elongated tubular body having a bore extending along a longitudinal axis, said tubular body comprising first and second independent parts slidably contacting each other, the first and second independent parts each having an outer circumferential surface along a length thereof parallel to the longitudinal axis, and each having an elongated partial inner bore, such that the tubular body is capable of mounting a tendon or ligament within the partial inner bore.

Abstract: The invention is directed to a spinal fusion device, comprising a load bearing component and an anterior component, wherein the load bearing component and the anterior component are configured to mate together by complimentary coupling members, and further comprising an external outer plate configured to span two vertebrae, wherein the outer plate includes bores configured to receive bone screws for coupling to vertebrae.

Abstract: An interbody fusion device for fusion of vertebrae, and methods thereof. The device includes a first piece made of titanium having upper and lower surfaces configured to engage the endplates of two opposing vertebrae. The upper and lower surfaces include a plurality of barbed teeth configured to engage an endplate. The first piece includes an inner void area configured to receive a second piece. The second piece is configured to engage the first piece to slide over inner surfaces of the first piece become seated and mated in the first piece. The first and second pieces mate to form an assembled interbody fusion device that fits between two vertebrae.

Abstract: A method and apparatus is provided for use in spinal fusion procedures. An interbody fusion device has a first piece that is a load bearing device designed to bear the axial loading from the end plates of adjacent vertebrae. A second piece of the interbody fusion device is a retention component whose primary functions are to prevent migration of the load bearing device and loss or migration of graft material from within the load bearing device. A secondary function of the retention component is to address fixation of fasteners when the surgeon is confronted with a challenging access to adequate boney structures due to excessive curvature/angulation of the vertebrae column, minimal invasive surgery techniques, danger to surrounding vascular or neurological tissues, poor bone quality, or similar surgical complications. A tertiary function of the retention component is to provide better alignment and stabilization of misaligned vertebrae when spondylolisthesis is a significant factor.

Abstract: A method and apparatus is provided for use in spinal fusion procedures. An interbody fusion device has a first piece that is a load bearing device designed to bear the axial loading from the end plates of adjacent vertebrae. A second piece of the interbody fusion device is a retention device whose function is to prevent migration of the load bearing device. One or more fasteners secure the retention device to the vertebrae above and below the load bearing device. The fasteners cause the end plates of the vertebrae to compress the end plates to the load bearing device to facilitate proper fusion. The device includes a snap in mechanism for coupling the first piece to the second piece.

Abstract: Aspects of the claimed invention relate generally to devices for delivering bone graft compositions to implants that have been positioned between vertebral bodies during surgery and methods of using such devices. Embodiments of the invention provide ease of bone graft delivery in situ while providing an environment for the mixing of bone graft, insertion of the bone graft, and packing of the graft into the voids above and below the implant.

Abstract: A lipoaspirate collection device to aid in the collection and processing of human tissue and fluid obtained during liposuction for use in point-of-care cell therapy. The collection device includes a collection body and a collection cap. The collection cap may have a fluid port, a lipoaspirate port, a vacuum port, and a relief valve. Within the central cavity of the collection device, a cone shaped may be positioned such that the apex of the cone is positioned underneath the lipoaspirate inlet through which the lipoaspirate fluid and tissue are introduced.

Abstract: A method and apparatus is provided for use with a surgical implant to secure fasteners, such as bone screws or pins. An anti-backout mechanism is used to preventing migration of the fasteners after the implant is installed. In one example, an anti-backout mechanism includes a locking plate having a locked position and an unlocked position. The locking plate has one or more protrusions that are configured to prevent migration the fasteners when the locking plate is in the locked position.

Abstract: Embodiments of the claimed invention are directed to to a screw and screw driver which provides for a screw that is held in position on the driver for use in a variety of applications including surgery, auto mechanics, carpentry or any field where a screw driver instrument could be used. After the screw is driven into place, the driver is easily released and removed from the screw.

Abstract: A method and apparatus is provided for use in spinal fusion procedures. A one or two piece interbody fusion device has a fusion bearing component designed to bear the axial loading from the end plates of adjacent vertebrae. An optional retention piece prevents migration of the load bearing device. One or more fasteners secure the retention device to the vertebrae above and below the load bearing device. The fasteners cause the end plates of the vertebrae to compress the end plates to the load bearing device to facilitate proper fusion. An anti-backout mechanism prevents the fasteners backing out.

Abstract: The invention features an implant assembly for stabilization of a facet joint including an implant having a U-shaped body. The U-shaped body comprises a rounded front end, an open back end, first and second elongated components extending from the rounded front end, forming the U-shaped body and ending at the open back end and a helical structure extending within the U-shaped body that serves as a locking mechanism.

Abstract: The invention is directed to a method for therapeutic repair of an injury to bone or tissue comprising providing a structural component, wherein the structural component repairs the injury; and providing a therapeutic fluid, wherein the therapeutic fluid is located within the structural component.

Abstract: The invention comprises a combination of biological elements that will naturally remodel in vivo based on applied mechanical forces. The final composition will possess mechanical properties similar to cartilage or a disc, and significantly less stiff than bone or implants comprised of metals or plastics. The equilibrium stress conduction will minimize unnatural forces on neighboring healthy discs.

Abstract: The invention is directed to an anchor for fixing a tendon or a ligament in a bone comprising: an elongated tubular body having a bore extending along a longitudinal axis, said tubular body comprising first and second independent parts slidably contacting each other, the first and second independent parts each having an outer circumferential surface along a length thereof parallel to the longitudinal axis, and each having an elongated partial inner bore, such that the tubular body is capable of mounting a tendon or ligament within the partial inner bore.

Abstract: An embodiment of the invention is directed to a bone marrow aspiration device comprising a plurality of syringes, each of which operates in a series of sequential steps to obtain bone marrow of high quality and therapeutic value, i.e., having a high MSC/ml number. An embodiment of the invention preferably comprises three syringes, wherein a first syringe is used to aspirate bone marrow from a subject, a second syringe contains an anticoagulant, and the third syringe contains a mixture of the bone marrow aspirate and the anticoagulant.

Abstract: The invention is directed to a device for the concentration of fluids comprising a donor receptacle containing a fluid to be concentrated, the donor receptacle comprising a plunger; a receiving receptacle to receive the concentrated fluid, the receiving receptacle comprising a plunger; a concentrator device that is connected to the donor receptacle and the receiving receptacle; and a housing that encloses the donor and receiving receptacles and the concentrator device that the plungers of the donor and receiving receptacles are enclosed within chambers that are gas tight.

Abstract: The invention is directed to a work station for use in performing processing of patient samples, storing equipment and drugs in a hospital and the like, the cart having a lower housing having caster wheels mounted on the bottom thereof, the lower housing having angular-shaped side panels therearound which may be opened for entrance into all sides of the housing, and one or more of the side panels; an upper housing mounted on top of the lower housing, the upper housing having one or more side panels therearound; and one or more work areas mounted on top of the upper housing, the shelf adapted for receiving point-of-care equipment.

Abstract: An embodiment of the claimed invention is a therapeutic delivery device having a plurality of fenestrations located around the circumference of its distal portion and an opening at the tip. The opening at the tip and the plurality of fenestrations reduce the injection resistance, making it easy to use, and ensure an even distribution of the injected material at the recipient location.