Abstract: The invention is directed to concentrating autologously-derived plasma, using the concentrated plasma fluid to dilute the patient's cells and applying the combination of concentrated fluid with cells at a site of pathology or mixing the combination of concentrated fluid with cells with a particulate material like a bone void filler prior to placing the mixture at a site of pathology.

Abstract: The invention is directed to a method for isolating stromal cells to form a therapeutic composition; and administering said therapeutic composition to the subject. A further embodiment of the invention is directed to therapeutic compositions comprising isolated stromal cells.

Abstract: The invention is directed to an interbody fusion device comprises a fusion bearing device and a retention device and further comprises two bone screws that pass through the retention device and into the vertebral bodies. When implanted, the construct is flush with the anterior face of the vertebras and provides support and temporary fixation for the ultimate fusion of the vertebral bodies.

Abstract: The invention is directed to a spinal fusion device, comprising a load bearing component and an anterior component, wherein the load bearing component and the anterior component are configured to mate together by complimentary coupling members, and further comprising an external outer plate configured to span two vertebrae, wherein the outer plate includes bores configured to receive bone screws for coupling to vertebrae.

Abstract: A method and apparatus is provided for use in spinal fusion procedures. An interbody fusion device has a first piece that is a load bearing device designed to bear the axial loading from the end plates of adjacent vertebrae. A second piece of the interbody fusion device is a retention component whose primary functions are to prevent migration of the load bearing device and loss or migration of graft material from within the load bearing device. A secondary function of the retention component is to address fixation of fasteners when the surgeon is confronted with a challenging access to adequate boney structures due to excessive curvature/angulation of the vertebrae column, minimal invasive surgery techniques, danger to surrounding vascular or neurological tissues, poor bone quality, or similar surgical complications. A tertiary function of the retention component is to provide better alignment and stabilization of misaligned vertebrae when spondylolisthesis is a significant factor.

Abstract: A medical device comprising a non-enclosed housing configured to fit between two adjacent vertebrae; one or more housing fasteners extending at least partially through the housing, one or more driving mechanisms operationally positioned in relationship to at least one housing fastener, such that activation of at least one driving mechanism engages and drives at least one housing fastener to compress into at least one adjacent vertebrae and one or more plates removably coupled to the housing.

Abstract: A method of securing a portion of a spine is disclosed that includes preparing a first tunnel through a first spinous process and a second tunnel through a second spinous process of a spine, affixing one pair of complementary plates to each tunnel on each side of the spinous process, and affixing a rod into troughs in plates on one side of the spinous process.

Abstract: Aspects of the claimed invention relate generally to devices for delivering bone graft compositions to implants that have been positioned between vertebral bodies during surgery and methods of using such devices. Embodiments of the invention provide ease of bone graft delivery in situ while providing an environment for the mixing of bone graft, insertion of the bone graft, and packing of the graft into the voids above and below the implant.

Abstract: A system and method for isolating and separating lipoaspirate particles. The system includes a generally cylindrical container having a lid and a bottom wherein the container includes at least one input port positioned to permit a lipoaspirate fluid to enter the container above the bottom; and a source of a vacuum coupled to the container to provide a partial vacuum during use of the system.

Abstract: A method and apparatus is provided for use in spinal fusion procedures. An interbody fusion device has a first piece that is a load bearing device designed to bear the axial loading from the end plates of adjacent vertebrae. A second piece of the interbody fusion device is a retention device whose function is to prevent migration of the load bearing device. One or more fasteners secure the retention device to the vertebrae above and below the load bearing device. The fasteners cause the end plates of the vertebrae to compress the end plates to the load bearing device to facilitate proper fusion.