Patents Assigned to Stellenbosch University
  • Publication number: 20150292773
    Abstract: A support structure (10) for carrying a plurality of heliostats (12) is provided. The support structure (10) includes a frame (20) formed from a number of girders (22). The frame has a triangular outer perimeter and a plurality of mountings (26) for carrying the heliostats (12) are provided along the perimeter. At least one mounting (26) is provided at or near each vertex (16) of the triangular outer perimeter of the frame (20), and at least one additional mounting (26) is provided part-way along each side (17) of the triangular outer perimeter of the frame (20).
    Type: Application
    Filed: November 6, 2013
    Publication date: October 15, 2015
    Applicant: STELLENBOSCH UNIVERSITY
    Inventors: Karel Johan Malan, Paul Gauché
  • Patent number: 9072704
    Abstract: A new use for paracetamol in a method of treating glaucoma, which method comprises administering to a patient in need of such treatment 500 mg to 1000 mg of paracetamol in oral format 4 to 6 hourly. An ophthalmic solution is also provided containing between 0.1 to 5% of paracetamol which is administered as one to two drops in each eye 4 to 6 hourly. The ophthalmic solution further includes one or more of the following excipients: hydroxypropylmethylcellulose, benzalconium chloride, polyacrylic acid such as Teargel®.
    Type: Grant
    Filed: October 2, 2013
    Date of Patent: July 7, 2015
    Assignee: Stellenbosch University
    Inventor: David Meyer
  • Publication number: 20150141279
    Abstract: A method of diagnosing tuberculosis (TB) disease and distinguishing between active TB and latent TB infection in a subject is described herein. A sample from the subject is stimulated with at least one Mycobacterium tuberculosis (M.tb) infection phase-dependent antigen selected from Rv0081, Rv2032, Rv1737c, Rv2389c, Rv0867c, TB18.2, Rv2099c, Rv1733c, M.tb PPD, PHA and ESAT-6/CFP-10 and the presence of at least one host marker in the sample is detected, the host marker being selected from EGF, TGF-?, TNF-?, VEGF, RANTES, IL-12(p40), IL-12(p70), IL-10, IP-10, IFN-?2, fractalkine, IFN-?, IL-13, IL-1Ra, IL-3, IL-4, IL-5, MIP-1?, ENA-78, BCA-1, TARC, X6-Ckine, eotaxin, eotaxin-2, SCF, APOA-1, APOE, HPALBN, HCF, Serum amyloid protein A (SAA), C-reactive protein (CRP), serum amyloid protein P (SAP), TIMP-1, MIP-1?, IL-6, GM-CSF, IL-1?, MMP-9, MMP-2, MCP-1, TRAIL, IL-15, IL-17F, IL-22, TNF-?, MCP-2 and MCP-4. Additional host markers may also be detected in an unstimulated sample from the subject.
    Type: Application
    Filed: May 27, 2013
    Publication date: May 21, 2015
    Applicant: Stellenbosch University
    Inventors: Gerhard Walzl, Novel Njweipi Chegou, Paulin Essone Ndong
  • Publication number: 20150120567
    Abstract: A system and method for monitoring third party access to a restricted item is provided. Key data is embedded in the restricted item, the key data being associated with a store of value and usable to conduct a transaction against the store of value. A record of the transaction becomes visible in a transaction ledger. The transaction ledger is monitored to determine whether a transaction against the store of value has occurred, and the restricted item is designated as accessed by a third party in the event that a transaction against the store of value has occurred.
    Type: Application
    Filed: May 22, 2014
    Publication date: April 30, 2015
    Applicant: Stellenbosch University
    Inventors: Gert-Jan VAN ROOYEN, Frederick Johannes LUTZ, Herman Arnold ENGELBRECHT
  • Patent number: 8916086
    Abstract: A process is provided for producing fibers which includes forming a plurality of bubbles on the surface of a fiber spinning solution, applying a voltage between the solution and a counter-electrode spaced apart therefrom to cause jets to extend from the bubbles to the counter-electrode, and treating the solution with a surfactant to stabilize the bubbles.
    Type: Grant
    Filed: April 17, 2008
    Date of Patent: December 23, 2014
    Assignee: Stellenbosch University
    Inventors: Anton Eugene Smit, Ronald Douglas Sanderson
  • Publication number: 20140367243
    Abstract: A dephlegmator is provided comprising two stages connected in series wherein a first stage includes an air-cooled reflux condenser and a second stage includes a generally horizontal tube bundle of smooth or finned tubes that can be operated selectively in either an air-cooled (dry) mode under selected ambient conditions or in a wet evaporatively cooled mode under other selected ambient conditions including that of elevated ambient temperature. Spray nozzles may be installed above the tube bundle whereby water can be sprayed onto the tube bundle. One or more collection troughs are preferably provided beneath the tube bundle for collecting run-off water and enabling recycling of excess deluge water. Preferably, the tube bundle comprises at least two, and preferably three groups of tubes communicating with each other wherein the second group of tubes has appreciably fewer tubes in it than the first group of tubes and any third group of tubes has appreciably fewer tubes in it than the second group of tubes.
    Type: Application
    Filed: July 10, 2012
    Publication date: December 18, 2014
    Applicant: STELLENBOSCH UNIVERSITY
    Inventors: Detlev G. Kröger, Hanno Carl Rudolf Reuter
  • Publication number: 20140308724
    Abstract: The present invention is directed to a yeast strain, or strains, secreting a full suite, or any subset of that full suite, of enzymes to hydrolyze corn starch, corn fiber, lignocellulose, (including enzymes that hydrolyze linkages in cellulose, hemicellulose, and between lignin and carbohydrates) and to utilize pentose sugars (xylose and arabinose). The invention is also directed to the set of proteins that are well expressed in yeast for each category of enzymatic activity. The resulting strain, or strains can be used to hydrolyze starch and cellulose simultaneously. The resulting strain, or strains can be also metabolically engineered to produce less glycerol and uptake acetate. The resulting strain, or strains can also be used to produce ethanol from granular starch without liquefaction.
    Type: Application
    Filed: February 12, 2014
    Publication date: October 16, 2014
    Applicants: Stellenbosch University, Mascoma Corporation
    Inventors: Elena BREVNOVA, John E. McBride, Erin Wiswall, Kevin S. Wenger, Nicky Caiazza, Heidi Hau, Aaron Argyros, Frank Agbogbo, Charles F. Rice, Trisha Barrett, John S. Bardsley, Abigail Foster, Anne K. Warner, Mark Mellon, Ryan Skinner, Indraneel Shikhare, Riaan Den Haan, Chhayal V. Gandhi, Alan Belcher, Vineet B. Rajgarhia, Allan C. Froehlich, Kristen M. Deleault, Emily Stonehouse, Shital A. Tripathi, Jennifer Gosselin, Yin-Ying Chiu, Haowen Xu
  • Patent number: 8778254
    Abstract: A method and apparatus provided for the production of fine fibers by electrospinning fibers by applying an electrical field between a primary electrode and a counter electrode (5) spaced apart from the primary electrode and extending generally parallel thereto wherein at least an operative surface of the primary electrode is coated with a polymer solution (3) and an electric field of sufficient magnitude is generated between the primary electrode and counter electrode to cause the formation of fine fibers (9) in the space between the electrodes. The operative surface of the primary electrode that is coated with polymer solution is made up of appropriate portions of the surfaces of a multitude of operatively semi-submerged, loose (unattached) elements (1, 11, 17, 21) supported on the bottom of a trough (2) or tray or another support member or members (12, 18, 22).
    Type: Grant
    Filed: June 23, 2009
    Date of Patent: July 15, 2014
    Assignee: Stellenbosch University
    Inventors: Anton Eugene Smit, Ronald Douglas Sanderson
  • Publication number: 20140151910
    Abstract: A splash grid is provided for installation in a rain zone of liquid gas contacting industrial equipment. The splash grid has a supporting frame assembly and multiple generally parallel elongate elements supported by the frame assembly. The elongate elements each has a transverse dimension, in plan view, not exceeding 3 mm, and a spacing in plan view not exceeding 10 mm. The elongate elements may be of a molded plastic material that is optionally integral with a surround that forms, or is attached to, the supporting frame assembly. Alternatively, the elongate elements may be separately manufactured flexible filament or cord supported by a surround that forms or is attached to the supporting frame assembly. The elongate elements may be staggered in the vertical direction and gaps may be provided for larger objects to pass through the splash grid. A liquid cooling installation having a rain zone fitted with a splash grid is also provided.
    Type: Application
    Filed: July 10, 2012
    Publication date: June 5, 2014
    Applicant: STELLENBOSCH UNIVERSITY
    Inventors: Hanno Carl Rudolf Reuter, Detlev Gustav Kröger
  • Patent number: 8729338
    Abstract: A method of modifying at least one carbohydrate in a tissue of a plant is described. The method is typically applied to a sugarcane plant of the genus Saccharum method and includes the steps of inserting into a plant cell a gene silencing cassette which includes nucleic acid operably linked to transcription elements such as a monocotyledonous promoter for transcribing the nucleic acid in a plant cell, wherein transcription of the nucleic acid decreases activity of UMP synthase. The method further includes the steps of regenerating a transgenic plant from the plant cell and producing the tissue with increased carbohydrate content. Vectors for use therefor, as well as a transformed plant cell and a transgenic plant or plant part containing or derived from a transformed plant cell are also described.
    Type: Grant
    Filed: September 17, 2010
    Date of Patent: May 20, 2014
    Assignees: Stellenbosch University, South African Sugarcane Research Institute
    Inventors: Gino Boussiengui-Boussiengui, Jens Kossmann
  • Publication number: 20140045946
    Abstract: A new use for paracetamol in a method of treating glaucoma, which method comprises administering to a patient in need of such treatment 500 mg to 1000 mg of paracetamol in oral format 4 to 6 hourly. An ophthalmic solution is also provided containing between 0.1 to 5% of paracetamol which is administered as one to two drops in each eye 4 to 6 hourly. The ophthalmic solution further includes one or more of the following excipients: hydroxypropylmethylcellulose, benzalconium chloride, polyacrylic acid such as Teargel®.
    Type: Application
    Filed: October 2, 2013
    Publication date: February 13, 2014
    Applicant: Stellenbosch University
    Inventor: David Meyer
  • Publication number: 20140000583
    Abstract: A thermal storage facility stores thermal energy at elevated temperature. The facility includes an enclosure for retaining a thermal storage medium; primary heat transfer surfaces for transferring heat from a circulating heat transfer fluid; and secondary heat transfer surfaces for transferring heat from the thermal storage medium to steam pipes associated with a power generation facility. The thermal storage medium is a metallic phase change material, preferably having a melting temperature above 500° C., interposed between the primary heat transfer surfaces and the secondary heat transfer surfaces. Solar power installations can incorporate one or more of the thermal storage facilities.
    Type: Application
    Filed: March 6, 2012
    Publication date: January 2, 2014
    Applicant: STELLENBOSCH UNIVERSITY
    Inventor: Johannes Paulus Kotze
  • Publication number: 20130244295
    Abstract: The invention relates to the combination of the TLG1 glucoamylase from Thermomyces lanuginoses with: (i) the SFA1 alpha-amylase from Saccharomycopsis fibuligera; and/or (ii) the LKA alpha-amylase. The enzyme combinations may be expressed in a host cell (e.g. in Saccharomyces cerevisiae) or provided as an enzyme composition. Methods for making the enzyme combinations of the invention are provided. The invention also relates to a yeast strain which exhibits amylolytic activity and promising fermentative abilities. Processes for producing a fermentation product (in particular alcohol) from starch-containing material are described.
    Type: Application
    Filed: April 12, 2010
    Publication date: September 19, 2013
    Applicants: Universita Degli Studi Di Padova, Stellenbosch University
    Inventors: Willem Heber Van Zyl, Tania Jooste, Johann Ferdinand Gorgens, Maryna Saayman, Lorenzo Favaro, Marina Basaglia, Sergio Casella
  • Publication number: 20130233501
    Abstract: The invention provides a method of modifying soluble xylan which contains glucuronic acid and/or arabinose side chains so that it can be adsorbed onto other substrates. The method includes the steps of enzymatically modifying the xylan by selectively removing glucuronic acid and/or arabinose side chains from the xylan with ?-D-glucuronidase and/or ?-L-arabinofuranosidase, and allowing the modified xylan to adsorb onto the substrate. The substrate may be a cellulosic substrate like pulp or paper or a non-cellulosic substrate. The enzymes are able to remove a sufficient number of the xylan side chains so as to decrease water solubility of the xylan, induce xylan precipitation and allow adsorption of the xylan onto other substrates. A pulping process which incorporates modification of xylan and adsorption onto cellulosic material is also provided, as are products which contain the modified xylan.
    Type: Application
    Filed: June 7, 2011
    Publication date: September 12, 2013
    Applicant: STELLENBOSCH UNIVERSITY
    Inventors: Willem Heber Van Zyl, Annie Fabian Abel Chimphango, Johann Ferdinand Gorgens
  • Patent number: 8522520
    Abstract: A yarn spun from a plurality of nano-fibers is provided and is characterized in that at least some of the nano-fibers are folded with the folds occurring at predeterminable distances which are integer multiples of a specific spacing. The folds result from spinning the nano-fibers onto a plurality of moving conductive strips which are inclined to their direction of movement. A process and apparatus for producing such yarn is also provided.
    Type: Grant
    Filed: October 23, 2007
    Date of Patent: September 3, 2013
    Assignee: Stellenbosch University
    Inventors: Anton Eugene Smit, Ronald Douglas Sanderson
  • Publication number: 20130214541
    Abstract: The invention relates to an electrical energy conversion system (11) which is particularly suited for use in wind energy conversion systems. The system includes two magnetically separated permanent magnet machines (25, 27) linked by a freely rotating rotor (19) housing permanent magnets (39). The first machine is typically a synchronous generator, and the second an induction generator. The synchronous generator (25) has a stationary stator (21) which is connectable to an electrical system such as an electricity grid, and the induction generator (27) has a rotor (17) which is connectable to a mechanical drive system such as, for example, a wind turbine.
    Type: Application
    Filed: August 4, 2011
    Publication date: August 22, 2013
    Applicant: STELLENBOSCH UNIVERSITY
    Inventors: Maarten Jan Kamper, Johannes Hendrik Jacob Potgieter, Johan Nico Stander
  • Publication number: 20130185037
    Abstract: A system for modelling the conversion of crystalline insoluble cellulose to ethanol is provided which includes a processor configured to calculate the production rate for ethanol based on a number of inputs and as a function of specific equations. The system can form part of a control system for controlling the operation of a plant which produces ethanol from cellulose.
    Type: Application
    Filed: July 8, 2011
    Publication date: July 18, 2013
    Applicant: STELLENBOSCH UNIVERSITY
    Inventors: Willem Heber Van Zyl, Josebus Maree Van Zyl, Thomas Michael Harms, Engene Van Rensburg, Lee Rybeck Lynd
  • Publication number: 20130089592
    Abstract: The invention provides a method of enzymatically modifying xylan by selectively removing glucuronic acid and/or arabinose side chains from the xylan with a-D-glucuronidase and/or a-L-arabinofuranosidase, and allowing the modified xylan to form into a hydrogel when the xylan becomes insoluble. A bioactive substance, such as a protein, enzyme, antimicrobial agent, bactericide or pharmaceutical compound can be added to the xylan so that the substance is encapsulated within the hydrogel or incorporated onto its surface. The hydrogel can be used as a drug delivery agent, such as for sustained-release or targeted drug delivery, rectal drug delivery or a dressing for a wound, burn or scar. The hydrogel can also be used as a coating, such as on medical gloves, catheters, surgical drainage systems, utensils or the like, or can be used in a scaffold for tissue engineering.
    Type: Application
    Filed: June 7, 2011
    Publication date: April 11, 2013
    Applicant: STELLENBOSCH UNIVERSITY
    Inventors: Willem Heber Van Zyl, Annie Fabian Abel Chimphango, Johann Ferdinand Gorgens
  • Publication number: 20120180161
    Abstract: A method of modifying at least one carbohydrate in a tissue of a plant is described. The method is typically applied to a sugarcane plant of the genus Saccharum method and includes the steps of inserting into a plant cell a gene silencing cassette which includes nucleic acid operably linked to transcription elements such as a monocotyledonous promoter for transcribing the nucleic acid in a plant cell, wherein transcription of the nucleic acid decreases activity of UMP synthase. The method further includes the steps of regenerating a transgenic plant from the plant cell and producing the tissue with increased carbohydrate content. Vectors for use therefor, as well as a transformed plant cell and a transgenic plant or plant part containing or derived from a transformed plant cell are also described.
    Type: Application
    Filed: September 17, 2010
    Publication date: July 12, 2012
    Applicants: South African Sugarcane Research Institute, Stellenbosch University South African Sugarcane Research Institute
    Inventors: Gino Boussiengui-Boussiengui, Jens Kossmann
  • Publication number: 20120169063
    Abstract: A new configuration for a double-sided rotor, radial flux, air-cored, permanent magnet electric generator (1) is disclosed. The generator (1) includes two radially spaced apart rotor portions (33, 35) defining an air gap between them and each having a plurality of alternating polarity permanent magnets (41) arranged on their inner surfaces, mounted for rotation in the air gap. A modular stator (43) is positioned in the air gap and includes a base (45) having attachment formations (60) spaced apart about its surface and a plurality of individually moulded, polymeric resin stator modules (53). Each stator module (53) has complementary attachment formations (59) for attachment to the base (45) and includes at least one non-overlapping compact wound coil (61) which is embedded within the resin.
    Type: Application
    Filed: September 17, 2010
    Publication date: July 5, 2012
    Applicant: Stellenbosch University
    Inventors: Johannes Abraham Stegmann, Maarten Jan Kamper