Abstract: A method for simulating a stochastic phenomenon, particularly one employing a Monte Carlo method, includes a step for generating random numbers having a nonuniform density function &rgr;(x) based on an ideal model of a chaotic dynamic system in the form Xn+1=f(Xn). The ideal model of chaotic map F(x) is a class of an algebraic map derived from an addition theorem of an elliptic function. The nonuniform density function &rgr;(x) is expressed by an algebraic function of a dynamical variable x. Examples of the ideal model of the chaotic map F(x) include a generalized Ulam-von Neumann map and a generalized cubic map. The nonuniform density function &rgr;(x) of the chaotic maps has the form Xn+1=F(Xn). The class of chaotic dynamical systems is ideal in the sense that the invariant measure &rgr;(x)dx satisfies the ergodic property required by the Monte Carlo method. Thus, a statistical simulation can be performed in the same manner as the conventional Monte Carlo method.

Abstract: A method for judging a possibility of the onset of bovine leukemia caused by bovine leukemia virus BLV, wherein a bovine individual, in which an amino acid sequence defined by the amino acid numbers 75 to 78 of the &bgr;1 domain of the bovine MHC Class II DR&bgr; chain is Val-Asp-Thr-Tyr, is judged to have a possibility of the onset of the leukemia; and a method for judging a resistance to the onset of bovine leukemia caused by the bovine leukemia virus BLV, wherein a bovine individual, in which an amino acid defined by the amino acid number 78 of the &bgr;1 domain of the bovine MHC Class II DR&bgr; chain is Val, is judged to have a resistance to the onset of the leukemia.

Abstract: A composition for prevention and extermination of plant disease which comprises a biocidal inorganic compound, an amphoteric surfactant, and at least one member selected from the group consisting of a nonionic surfactant and an anionic surfactant. The composition exhibits residual activity for a long period of time without phytotoxicity.

Abstract: The invention provides a method for selectively amplifying a cDNA synthesized from an mRNA expressed only in an extremely small quantity. The method comprises synthesizing a cDNA from a target mRNA using an oligonucleotide primer complementary to at least a part of the 3′ untranslated region of the mRNA and amplifying the resultant cDNA using a 5′ primer and a 3′ primer which is located 5′ upstream of the oligonucleotide primer for synthesizing a cDNA.

Abstract: The present invention relates to a site-specific endonuclease which recognizes a specific nucleotide sequence, to a gene coding for the endonuclease, to a recombinant vector containing the gene, to a transformant containing the vector, and to a process for producing the endonuclease.

Abstract: A neurogenesis inducing gene coding for the following protein (a) or (b): (a) a protein consisting of the amino acid sequence shown in SEQ ID NO: 2 (b) a protein which consists of the amino acid sequence shown in SEQ ID NO: 2 having deletion, substitution or addition of at least one amino acid and which has neurogenesis inducing activity.

Abstract: Disclosed are peptides represented by IVC1SLC2SC3TAW and C1SLC2SC3 wherein I stands for isoleucine, V for valine, C1 for cysteine, C2 for cysteinesulfinic acid, C3 for cysteinesulfenic acid, S for serine, L for leucine, T for threonine, A for alanine, and W for tryptophan. These peptides can impart photoreactivity to a protein by binding to a non-heme iron. Also disclosed are methods for imparting photoreactivity to cells by introducing the peptide sequences into at least one protein which is involved in a metabolic system and/or energy metabolic system of the cells. There can be provided peptide sequences with a shorter peptide chain capable of imparting photoreactivity, which can be easily introduced into a protein with a little risk in degrading original function of the protein. There are also provided methods enabling control of metabolic reactions by imparting photoreactivity to cells with the peptides.

Abstract: Disclosed are 3′-deoxyribonucleotide derivatives represented by the following general formula [I]: Q—V—(CH2)n—NH—R  [I] wherein Q represents a 3′-deoxyribonucleotide residue, n represents an integer not less than 4, V represents —C≡C— or —CH═CH—, and R represents a fluorescent group. The above 3′-deoxyribonucleotide derivatives are derivatives with improved rates for incorporation using RNA polymerases, which are useful as terminators in the DNA sequence determination methods utilizing RNA polymerases.

Abstract: An anti-tumor composition containing cytotrienin (I), (II), (III) or (IV) as the active ingredient, which compounds are produced by culturing a bacterium which produces cytotrienin (I), (II), (III) or (IV), in a medium and accumulating cytotrienin (I), (II), (III) or (IV) in the medium and harvesting the product.

Abstract: A phase-shift digital holographic apparatus shifts the phase of a reference wave by a phase shifting means, produces holographic image data by a holographic image pickup means having an image forming surface on which an object wave and the reference wave fall simultaneously, processes a plurality of holographic image data produced by the object wave and a plurality of reference waves of different phases determined by shifting the phase of the reference wave by the phase shifting means by an object wave calculating means to calculate phase data on the phase of the object wave and amplitude data on the amplitude of the object wave, and constitutes object wave data of the phase data on the phase of the object wave and the amplitude data on the amplitude of the object wave calculated by the object wave calculating means by a reproduced image calculating means and subjects the object wave data to a predetermined transformation process to calculate a reproduced image.

Abstract: A method and a system for magnetic resonance imaging using echo planar method enable obtaining MRI images reduced in ghost artifacts. The magnetic resonance imaging system realizing the magnetic resonance imaging method includes a gradient coil for fast switching (inverting) a gradient magnetic field in a magnetostatic field applied to an object to be analyzed by a magnetostatic field generator, a receiver for receiving magnetic resonant signals from atomic nuclei of the object to be analyzed as echo signals necessary for filling a k-space, k-space data developer for developing the signals converted into a digital form over the a k-space as echo data, data collector for collecting echo data of the same phase encoding data in two frequency encoding directions for about half the k-space, and imager for making an image by classifying the echo data by frequency encoding direction, performing Fourier transformation separately to obtain images, and adding absolute number processed images to improve S/N.

Abstract: An amino acid composition comprising the following amino acids at the following molar ratio: proline (12.6 to 23.4), alanine (8.4 to 15.6), glycine (13.3 to 24.9), valine (8.2 to 15.4), threonine (5.0 to 9.4), eucine (4.3 to 8.1), histidine (1.8 to 11.9), serine (1.7 to 3.3), lysine (6.0 to 11.2), isoleucine (3.1 to 5.9), glutamic acid (2.2 to 10.4), arginine (2.4 to 4.6), phenylalanine (2.6 to 5.0), tyrosine (4.2 to 7.8) and trypsin (1.5 to 2.9). The composition supplements blood amino acids reduced during hard exercise and shows effects to improve motor function, to reduce fatigue after exercise and to help recovery from the fatigue.

Abstract: A tool is constructed by a plurality of diamond columns 22 arranged so as to protrude from a working surface and a conductive bond member 24 for integrally fixing the diamond columns. The conductive bond member is electrolytically dressed while a conductive liquid is supplied between the bond member and an electrode 4 which faces the bond member at a distance, thereby enabling the diamond columns 22 to protrude. By this construction, the tool can be applied to both an efficient rough cutting for a ductile material and a precise grinding for a brittle material without detaching or re-attaching a workpiece, the relatively soft ductile material such as aluminum, copper, or plastic can be worked with a deep cut, the brittle material such as monocrystal silicon, glass, or tungsten carbide can be efficiently and stably ground, so that a fluctuation of a working position due to wear can be compensated.

Abstract: A method for preparing a cDNA from a mRNA using a reverse transcriptase wherein reverse transcription is performed at a temperature at which the mRNA does not take a secondary structure, for example, at a temperature of 45° C. or more. The method is performed, for example, using a heat-labile reverse transcriptase in the presence of a substance exhibiting chaperone function having chaperone function such as saccharides. The method is performed, for example, in the presence of metal ions necessary for activation of the reverse transcriptase and a chelating agent for the metal ions such as a deoxynucleotide triphosphate. The method is capable of reverse transcription over the full length of mRNA template even if the mRNA is a long chain mRNA and, as a result, producing a full length cDNA.

Abstract: Novel GalNAc&agr;2,6-sialyltransferases P-B1 and P-B3; GalNAc&agr;2,6-sialyltransferase genes encoding the above GalNAc&agr;2,6-sialyltransferases P-B1 and P-B3; and an extracellularly releasable protein catalyzing GalNAc&agr;2,6-sialic acid transfer which comprises a polypeptide portion as being an active domain of the GalNAc&agr;2,6-sialyltransferase P-B1 or P-B3 together with a signal peptide are provided. Also provided is a process for preparing a sialyltransferases which enables efficient recovery of a sialyltransferase expressed in a large quantity in microorganisms.

Abstract: A metal bond grinding wheel 12 having a horizontal working surface 12a, a holding and rotating means 14 for a workpiece having a horizontal supporting surface 14a opposite to said working surface 12a, a voltage applying means 16 having the metal bond grinding wheels and an electrode 16a installed oppositely to the working surfaces in an uncontacted state and applying a pulsed voltage between them, a grinding fluid feeding means 18 for feeding an electroconductive grinding fluid to the working surfaces are installed.

Abstract: An EL element and a laser luminescent element are capable of emitting ultraviolet rays with high wavelength purity. The ultraviolet electroluminescent element includes a thin film made from one of a polymer and an oligomer in which the elements, selected from Si, Ge, Sn, and Pb, and directly bonded. The elements selected may be the same as or different from each other. The film is disposed between two electrodes. At least one of the electrodes is transparent. The laser luminescent element includes a thin film made from one of a polymer and an oligomer in which the elements selected from Si, Ge, Sn, and Pb, are directly bonded, and is disposed between two electrodes. The elements may be the same as or different from each other.

Abstract: Embryonic stem cell lines C-6 and C-2, Cr/A-3, DB1, and B6-26 have been derived from the inbred mice strains C3H/HeN, BALB/c, DBA/1J, and C57BL/6N, respectively. The embryonic stem cells are alkaline phosphatase positive and express a C3H specific antigen. The embryonic stem cell lines are useful in genetic research and the production of knockout mice.

Abstract: In order to form a fine pattern at high speed with respect to a material such as quartz glass exhibiting a remarkable band gap, having a short wavelength at absorption edge of light, and having high bond energy between constituent atoms, laser beam being transparent as to a material to be worked is irradiated thereupon, at the same time, plasma is produced at a place close to an objective surface of the material to be worked, and ablation is generated on the objective surface of the material to be worked by means of interactions between the plasma and laser beam irradiated upon the material to be worked, thereby to work the material.

Abstract: The purpose of the invention is to provide a solid model creation apparatus that is small in size and inexpensive. A multiplicity of blue LEDs are prepared, optical fibers are connected thereto, and GRIN lenses are arranged at the ends of the tips of the respective optical fibers to constitute an exposing head 23. The exposing head 23 forms images of the end faces of the respective optical fibers in a photocurable resin exposure region 24 as light spots 55. The diameter of a light spot 55 is, for example, 0.5 mm, but the size of a pixel 71 within the exposure region 24 is much smaller; for example, 62.5&mgr;. The multiplicity of optical fibers at the exposing head 23 are arrayed in a matrix such that they are displaced in staggered fashion so that respective light spots 55 are lined up at the pitch 62.5&mgr; of the pixels 71 in the primary scan (Y-axis) direction.