Patents Assigned to The University of Tokyo
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Publication number: 20230211539Abstract: An object of the present invention is to provide a method for producing a polymeric molded product, the method enabling expansion of a temperature range that can be used for partial melting. The present invention provides a method for producing a polymeric molded product, which comprises subjecting a crystalline polyhydroxyalkanoate to a heating treatment at a temperature equal to or higher than a glass transition temperature; and melt-molding a polyhydroxyalkanoate yielded by the heating treatment, which comprises lamellar crystals that are different in lamellar thickness, in a temperature range where some of the lamellar crystals undergo melting and flowing, and the other balance lamellar crystals remain unmelted.Type: ApplicationFiled: June 2, 2021Publication date: July 6, 2023Applicants: Mitsubishi Gas Chemical Company, Inc., The University of TokyoInventors: Akira MAEHARA, Tadahisa IWATA, Taku OMURA, Taizo KABE
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Publication number: 20230212306Abstract: The present invention provides a pharmaceutical composition comprising an antibody which binds specifically to human TLR7 or monkey TLR7 and does not bind to mouse TLR7 or rat TLR7, and has an activity of inhibiting a function of human TLR7 or monkey TLR7, and the like.Type: ApplicationFiled: December 27, 2022Publication date: July 6, 2023Applicants: Daiichi Sankyo Company, Limited, The University of TokyoInventors: Kensuke Miyake, Yusuke Murakami, Yuji Motoi, Atsuo Kanno, Toshiyuki Shimizu, Umeharu Ohto, Takaichi Shimozato, Atsushi Manno, Takashi Kagari, Jun Ishiguro, Kensuke Nakamura, Takashi Isobe
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Patent number: 11683985Abstract: A thermoelectric conversion element is made of a material with a band structure having Weyl points in the vicinity of Fermi energy. The thermoelectric conversion element has a thermoelectric mechanism for generating electromotive force by the anomalous Nernst effect. A thermoelectric conversion device includes a substrate; and a power generator provided on the substrate and including a plurality of thermoelectric conversion elements. Each of the plurality of thermoelectric conversion elements has a shape extending in one direction, and is made of a material identical to that of the above-mentioned thermoelectric conversion element. The plurality of thermoelectric conversion elements is arranged in parallel to one another in a direction perpendicular to the one direction and electrically connected in series to one another in a serpentine shape.Type: GrantFiled: July 3, 2018Date of Patent: June 20, 2023Assignee: THE UNIVERSITY OF TOKYOInventors: Satoru Nakatsuji, Akito Sakai
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Patent number: 11674180Abstract: A method for determining a hyperexcitability in a subject comprising detecting a repeat expansion of TTTCA, TTTTA, or a complementary sequence thereof in a nucleic acid sample from the subject.Type: GrantFiled: February 12, 2019Date of Patent: June 13, 2023Assignee: The University of TokyoInventors: Shoji Tsuji, Hiroyuki Ishiura
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Publication number: 20230174767Abstract: A composition includes a thermoplastic polymer and a polyrotaxane. The polyrotaxane includes a plurality of cyclic molecules and a chain polymer passing through the plurality of the cyclic molecules in a skewering manner, at least a part of the hydroxyl groups of the plurality of cyclic molecules being substituted with a hydrophobic group. A group that enhances miscibility of the polyrotaxane to the thermoplastic polymeris bound to at least a part of the hydrophobic groups of each of the plurality of cyclic molecules.Type: ApplicationFiled: August 28, 2020Publication date: June 8, 2023Applicants: The Texas A&M University System, The University of TokyoInventors: Hung-Jue Sue, Chia-Ying Tsai, Glendimar S. Molero, Kohzo Ito, Koichi Mayumi, Shuntaro Uenuma, Shota Ando
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Publication number: 20230178735Abstract: An electrode active material has a high energy density, high output, and a superior cycle property with little decrease in capacity even after repeated charge and discharge. An electrode and a secondary battery can include the electrode active material. An electrode active material which contains a compound having a dithiadiazine group, and is used as an active material of a secondary battery that repeats charge and discharge by a battery electrode reaction, and electrode containing the electrode active material and a conductive material. In addition, a secondary battery wherein the electrode active material is contained in any one of a reaction starting material, a product, and an intermediate product of at least a discharge reaction of the battery electrode reaction.Type: ApplicationFiled: March 15, 2021Publication date: June 8, 2023Applicant: THE UNIVERSITY OF TOKYOInventors: Masaharu SATO, Hiroshi NISHIHARA, Ying WANG
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Publication number: 20230175949Abstract: An imaging flow cytometer includes: a flow channel in which an observation object flows and a length in a width direction is longer than a length in a height direction; an acoustic element configured to apply acoustic waves as standing waves to the flow channel; a light source that irradiates the flow channel with illumination light; an image sensor configured to image at least a line included in a cross section of the observation object crossing a flow line direction which is a direction in which the observation object flows in the flow channel by measuring or imaging the observation object passing through a position irradiated with the illumination light; and circuitry configured to generate an image in which the observation object is scanned in the flow line direction on the basis of a plurality of captured images acquired by the imaging unit imaging the line in a time series.Type: ApplicationFiled: September 10, 2021Publication date: June 8, 2023Applicant: The University of TokyoInventors: Sadao OTA, Masashi UGAWA
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Publication number: 20230173020Abstract: Establishment of pancreatic islet-like insulin producing cells by inducing differentiation of ES/iPS cells has been reported. However, no technique has been developed so far for producing functional pancreatic islet insulin-positive cells in a large amount. In addition, there are concerns regarding rejection responses, accidental immune responses, etc. The present invention provides pancreatic islet-like cells having Mycl gene introduced thereinto and a method that comprises inducing proliferation of pancreatic islet-like cells by transient expression of Mycl gene and then inducing degradation thereof into insulin producing cells.Type: ApplicationFiled: December 10, 2020Publication date: June 8, 2023Applicant: THE UNIVERSITY OF TOKYOInventors: YASUHIRO YAMADA, MICHITADA HIRANO
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Patent number: 11670756Abstract: To provide a negative electrode for a secondary battery and a secondary battery having a large energy density and a capacity less likely to reduce even after repeated charging and discharging, and manufacturing methods thereof. The above-described problem is solved by a negative electrode for a secondary battery (3) comprising a negative electrode active material layer (3?) including at least a silicon-based active material and a binder, and a negative electrode current collector (14) having a structural form in which the silicon-based active material has an amorphous region including lithium and island-shaped lithium carbonate is distributed in the amorphous region.Type: GrantFiled: October 31, 2018Date of Patent: June 6, 2023Assignee: THE UNIVERSITY OF TOKYOInventors: Hiroshi Nishihara, Mariko Miyachi, Masaharu Sato
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Patent number: 11666244Abstract: A foot sole pressure measurement instrument includes a measurement unit which is installed on a foot sole part of a subject and measures a pressure applied to the foot sole part of the subject, and an output unit configured to output data of the measured pressure.Type: GrantFiled: August 13, 2018Date of Patent: June 6, 2023Assignees: NIPPON TELEGRAPH AND TELEPHONE CORPORATION, THE UNIVERSITY OF TOKYOInventors: Shingo Tsukada, Hiroshi Nakashima, Nahoko Kasai, Hideo Hatta
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Publication number: 20230170107Abstract: Provided is a conductor material having high conductivity. The conductor material according to an embodiment of the present disclosure has a configuration in which a conjugated polymeric compound having an electron donating group containing a heteroatom in a side chain is doped with a dopant containing an anion selected from a nitrogen anion, a boron anion, a phosphorus anion and an antimony anion, and a counter cation. The anion is preferably an anion represented by Formula (1) below: where R1 and R2 are identical or different, and each represent an electron withdrawing group; and R1 and R2 may be bonded to each other to form a ring with an adjacent nitrogen atom.Type: ApplicationFiled: April 27, 2021Publication date: June 1, 2023Applicants: THE UNIVERSITY OF TOKYO, DAICEL CORPORATIONInventors: Toshihiro OKAMOTO, Tadanori KUROSAWA, Yu YAMASHITA, Junichi TAKEYA, Daiji IKEDA, Takeshi YOKOO, Yasuyuki AKAI
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Patent number: 11664749Abstract: A power supply circuit that outputs an electric power input from a vibration-driven energy harvesting element to an external load includes a rectifying circuit that rectifies an alternating current power input from the vibration-driven energy harvesting element; a first capacitor that accumulates a power output from the rectifying circuit; a chopper circuit that has a switching element controlling a chopper timing and has an input terminal connected to the first capacitor; and a control signal generation unit that supplies a control signal to the switching element, wherein: the control signal generation unit generates the control signal without referring to a voltage of the first capacitor.Type: GrantFiled: May 30, 2019Date of Patent: May 30, 2023Assignees: The University of Tokyo, Saginomiya Seisakusho, Inc.Inventors: Hiroshi Toshiyoshi, Hisayuki Ashizawa, Masahiro Morita
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Patent number: 11662148Abstract: In a heat exchanger, each of a plurality of heat exchange members includes: a flat pipe; and a heat transfer plate integrated with the flat pipe along a longitudinal direction of the flat pipe. A width direction of each of the flat pipes intersects with a direction in which the plurality of heat exchange members are arranged side by side. Each of the heat transfer plates includes an extending portion extending outward in the width direction of each of the flat pipes from at least one of one end of a corresponding one of the flat pipes in the width direction and another end of the corresponding one of the flat pipes in the width direction. Each of the flat pipes has one or more flat pipe bent portions, each forming a groove extending along the longitudinal direction of the flat pipes.Type: GrantFiled: August 3, 2017Date of Patent: May 30, 2023Assignees: Mitsubishi Electric Corporation, The University of TokyoInventors: Akira Ishibashi, Tsuyoshi Maeda, Shinya Higashiiue, Daisuke Ito, Shin Nakamura, Ryota Akaiwa, Akira Yatsuyanagi, Ryuichi Nagata, Eiji Hihara, Chaobin Dang, Jiyang Li
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Patent number: 11658309Abstract: A fuel cell is an ammonia fuel cell using an ammonia-containing fuel. A catalyst used for an anode of the fuel cell is a ruthenium complex having two first ligands and one second ligand, and the first ligand is pyridine or a condensed cyclic pyridine compound with or without a substituent, and the second ligand is 2,2?-bipyridyl-6,6?-dicarboxylic acid with or without a substituent on a pyridine ring.Type: GrantFiled: March 2, 2020Date of Patent: May 23, 2023Assignees: THE UNIVERSITY OF TOKYO, NISSAN CHEMICAL CORPORATIONInventors: Yoshiaki Nishibayashi, Kazunari Nakajima, Hiroki Toda, Shoichi Kondo, Takamasa Kikuchi
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Patent number: 11655269Abstract: To provide novel compounds that are promising as prodrug-type anticancer agents, a compound represented by general formula (I) or a salt thereof is provided.Type: GrantFiled: March 4, 2019Date of Patent: May 23, 2023Assignee: THE UNIVERSITY OF TOKYOInventors: Yasuteru Urano, Mako Kamiya, Kento Hayashi
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Patent number: 11655046Abstract: A safety management system to prevent unauthorized use, accident, resale, theft, and so forth of a flying object. The safety management system includes changing, at a motor controller, a power feeding amount to each drive unit based on an instruction from a main control unit, an authentication information storage unit which records registered identification information for performing operator authentication, an authentication accepting unit which accepts an input of input identification information, an operator authentication unit which performs operator authentication of an operator of the flying object based on the input identification information and the registered identification information, and a safety managing unit connected between a power source of the flying object and the motor controller of the flying object. The safety managing unit includes a switch which controls electrical connection between the motor controller and the power source based on the result of the operator authentication.Type: GrantFiled: April 21, 2016Date of Patent: May 23, 2023Assignees: The University of Tokyo, Blue Innovation Co., Ltd.Inventors: Shinji Suzuki, Takeshi Tsuchiya, Masayuki Kumada
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Publication number: 20230149558Abstract: It is an object of the present invention to provide a conjugate of a duocarmycin derivative and a biotin-modified dimer, which is useful for pretargeting methods. According to the present invention, a compound represented by the following formula (1) or formula (2) is provided: wherein R1 and R2 each independently represent a hydrogen atom, a lower alkyl group, or a lower alkoxycarbonyl group; one of R3, R4, and R5 represents —O-L7-(Xaa)m-L6-N3, and the remaining two each independently represent a hydrogen atom, a lower alkyl group, or a lower alkoxycarbonyl group; X represents a reactive group; L6 and L7 each independently represent a divalent linking group; Xaa represents an amino acid residue; m represents an integer of 2 to 10; and Me represents a methyl group.Type: ApplicationFiled: April 23, 2021Publication date: May 18, 2023Applicants: The University of Tokyo, SAVID THERAPEUTICS INC., TOHOKU UNIVERSITYInventors: Motomu KANAI, Kenzo YAMATSUGU, Toshifumi TATSUMI, Tatsuhiko KODAMA, Akira SUGIYAMA, Masanobu TSUKAGOSHI, Hidetoshi TOKUYAMA, Juri SAKATA
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Publication number: 20230148933Abstract: An electric signal transmission device including an electrode 11, disposed to be opposed to an electrogenic cell, and for sending and receiving electric signals to and from the electrogenic cell via the electrode 11.Type: ApplicationFiled: April 1, 2021Publication date: May 18, 2023Applicant: The University of TokyoInventor: Masataka WATANABE
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Publication number: 20230151141Abstract: Provided is a dopant with which a conductor material having high electrical conductivity can be formed. The present disclosure relates to a dopant containing a radical cation represented by Formula (1) and a counter anion. In Formula (1), R1 to R3 may be the same or different, and each denotes a monovalent aromatic group or a group represented by Formula (r). at least one of R1 to R3 is a group represented by Formula (r), and n indicates the valence of the radical cation and is equal to the quantity (n) of nitrogen atoms in the formula. In Formula (r), Ar1, Ar2, and Ar3 may be the same or different, and each denotes a divalent aromatic group, and Ar4, Ar5, Ar6, and Ar7 may be the same or different, and each denotes a monovalent aromatic group optionally having a substituent represented by Formula (sb) below. Furthermore, m and n may be the same or different, and each represents an integer of 0 or greater.Type: ApplicationFiled: April 15, 2021Publication date: May 18, 2023Applicants: THE UNIVERSITY OF TOKYO, DAICEL CORPORATIONInventors: Toshihiro OKAMOTO, Tadanori KUROSAWA, Junichi TAKEYA, Daiji IKEDA, Takeshi YOKOO, Yasuyuki AKAI
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Patent number: 11650988Abstract: The database management system (DBMS) receives a first instruction specifying anonymization rule information corresponding to a column of the relation table, among anonymization rule information that is present for each column included in the relation table and shows a plurality of generalization rules. The DBMS reads the column from the relation table in response to the first instruction, and generates a temporary result obtained by generalizing each attribute value of the column based on any of a plurality of generalization rules. The DBMS generates an aggregate result obtained by aggregating the temporary result. The DBMS generates an anonymization method including generalization information indicating a correspondence relationship of each attribute value of the column and any of the plurality of generalization rules when the aggregate result satisfies a disclosure rule. The DBMS generates anonymization information as a result of processing the relation table based on the first anonymization method.Type: GrantFiled: September 23, 2020Date of Patent: May 16, 2023Assignees: HITACHI, LTD., THE UNIVERSITY OF TOKYOInventors: Yuya Isoda, Kazuhiko Mogi, Norifuml Nishikawa, Kazuo Goda, Yuto Hayamizu, Masaru Kitsuregawa