Abstract: An object is to provide a shape measurement system and a shape measurement method that allow deriving a three-dimensional shape of a linear object to be measured over a long distance and with high resolution.

Abstract: A small transistor type sensor capable of detecting a specific compound such as oxytocin is provided. The transistor type sensor includes a detection electrode that detects a compound by capturing the compound, and a field effect transistor that has a gate electrode connected to the detection electrode, wherein a surface of the detection electrode is provided with a film of a molecularly imprinted polymer having a space to which the compound is allowed to bond.

Abstract: The present invention is to provide a novel adsorbent which is low in cost, has versatility and has high adsorption ability. Specifically, the present invention is to provide an adsorbent containing a metal salt of a cyanometallic acid obtained by a reaction of a salt of a cyanometallic acid and a compound containing a metal element, wherein the reaction is carried out using the compound containing a metal element in an amount of less than 100 mol % of the theoretical amount relative to 1 mol of the salt of a cyanometallic acid, a method of producing the same, and a method for removing harmful ions from water using such an adsorbent.

Abstract: A monitoring system according to one aspect of the present disclosure includes: a sensor to measure physical quantities at one or a plurality of measurement points of a structural body; processing circuitry configured to acquire measured values from the measurer; a memory to store the measured values acquired from the measurer; and a data storage that, when one or some of the measured values stored in the memory satisfy a predetermined trigger condition, and as a result, it is determined that the structural body has received impact, records a group of data of the measured values which are within a certain time range and include the measured value based on which it is determined that the trigger condition is satisfied.

Abstract: An object of the present invention is to provide an information processing apparatus capable of more easily evaluating a depression state. The present invention is an information processing apparatus including: means for inputting voice data uttered by a subject; means for acquiring time-series data of sound pressure in the input voice data; and means for obtaining a Sound Pressure Change acceleration index that is an index based on a force toward a center and a force away from the center of the acquired time-series data of the sound pressure.

Abstract: A configuration of the present disclosure specifies a signal point of a specific component and a background point, based on time series two-dimensional spectroscopic image data of a gas; calculates a correlation coefficient between a time series detection signal at the signal point and a time series detection signal at the background point; and generates a time series detection signal of the specific component, based on a corrected time series detection signal obtained by subtracting a product of the correlation coefficient and the time series detection signal at the background point from the time series detection signal at the signal point.

Abstract: An adhesion-preventing material having a high adhesion-preventing effect has been demanded. An adhesion-preventing material including a sterilized biocompatible sponge-like laminate, wherein the sponge-like laminate comprises a sponge-like first layer and a sponge-like second layer each of which is at least partially crosslinked with a curing agent and comprises a low-endotoxin alginic acid monovalent metal salt, the alginic acid monovalent metal salt in the first layer has a weight average molecular weight of 10,000 to 2,000,000, the alginic acid monovalent metal salt in the second layer has a weight average molecular weight of 1,000 to 1,000,000, the weight average molecular weights are measured by a GPC-MALS method after a decrosslinking treatment, and the weight average molecular weight of the alginic acid monovalent metal salt in the first layer is higher than that in the second layer.

Abstract: A current interrupting device includes a current limiting element on a power supply path from a predetermined power supply to a load device. The current limiting element is configured to exhibit a current limiting action when current flowing in the power supply path exceeds a first current threshold value. The current interrupting device further includes a current diversion path switch, and a controller programmed to control on and off of the current diversion path switch. The controller is programmed to switch a current diversion path switch on from an off state when it is detected that current flowing in the current limiting element is limited to a second current threshold value after the current flowing in the current limiting element has exceeded the first current threshold value, and switch the switch off again after a predetermined switched-on holding time has elapsed since the switch has been switched on.

Abstract: The present disclosure provides a method for screening cells, the method including a step of preparing a plurality of cells which are tagged with a first barcode nucleic acid associated with a test target and treated with the test target, a step of sorting the plurality of cells based on cellular phenotype using an imaging cell sorter, and a step of identifying the test target used to treat each cell using the first barcode nucleic acid as an indicator.

Abstract: An analysis device configured to analyze a correlation between feature values in a cell in response to a stimulus includes: a cell-image acquiring unit configured to acquire a plurality of cell images in which the cell that is stimulated is captured; a feature value calculating unit configured to calculate a feature value for constituent elements that form the cell, based on the plurality of cell images acquired by the cell-image acquiring unit; a correlation calculating unit configured to use the feature value calculated by the feature value calculating unit and to calculate correlations between the constituent elements; a correlation selecting unit configured to select a first correlation from the correlations calculated by the correlation calculating unit; and an image selecting unit configured to select a first cell image from the plurality of cell images that are captured, based on the first correlation that is selected.

Abstract: A solution mixer comprising: a main flow path in which a solution circulates; at least one solution introduction flow path connected to the main flow path; and at least one solution discharge flow path connected to the main flow path, wherein the solution discharge flow path has at least one solution discharge flow path valve, and wherein the main flow path has at least one main flow path valve.

Abstract: The present invention aims to provide a warming composition showing a favorable dispersion stability after long-term storage, a high warming impact, and improvement of zeolite-specific deterioration of feeling of use, and to provide an aerosol formulation containing the warming composition. This object is achieved with a warming composition containing zeolite nanoparticles having an average particle size of not more than 500 nm, wherein the temperature of the composition is rapidly increased by heat generated by hydration reaction between the zeolite and water.

Abstract: The present invention relates to an inhibitory agent of membrane fusion between a virus envelope and a cell membrane of a host cell for the virus, wherein the inhibitory agent comprises a serine protease inhibitor, and a therapeutic agent or a therapeutic composition, comprising the inhibitory agent. More specifically, the present invention relates to the inhibitory agent, wherein the serine protease inhibitor is one or more of a compound represented by the following general formula (I) or a salt thereof, or a solvate or hydrate thereof, and a therapeutic agent or a therapeutic composition, comprising the inhibitory agent: wherein R1 represents a substituted or unsubstituted lower alkyl group, a substituted or unsubstituted lower alkenyl group, a substituted or unsubstituted aromatic hydrocarbon group, or a substituted or unsubstituted aromatic heterocyclic group, each of which may optionally comprise a heteroatom.

Abstract: [Problem] To develop a group of novel compounds with an inhibitory activity against the function of Pin1 so as to use them as candidate compounds for medicaments.

Abstract: The present invention is directed to a cyclic polypeptide having ubiquitin binding affinity (KD) of 0.1-100 nM. Further provided are methods for reducing deubiquitination activity of a cell, and for treating cancer in a subject in need thereof.

Abstract: Provided is a compound that is excellent in chemical stability, has a high solubility in a solvent, and exhibits an excellent carrier mobility. A compound represented by Formula (1): where in Formula (1), X1, X2, X3, and R1 to R10 are as defined in the specification.

Abstract: Objects of the present invention are to provide a novel phthalocyanine dye for use in photoimmunotherapy, and a method for producing the same, and to provide a conjugate of the above-described phthalocyanine dye and an antibody or a peptide. According to the present invention, a compound represented by the following formula (1) or a salt thereof is provided: wherein X represents a substituent having a hydrophilic group at the terminus thereof; L3, L4, L5, and L6 each independently represent a divalent linking group; Y represents a group capable of binding to an antibody or a peptide; R3 represents a substituent, such as an alkyl group containing 1 to 6 carbon atoms, an alkoxy group containing 1 to 6 carbon atoms, a halogen atom, —SR11, —SOR12, an aryl group containing 6 to 10 carbon atoms, —N(R13)(R14), or —NO2, wherein when a plurality of R3s are present, the plurality of R3s may be identical to or different from one another; and s represents an integer of 0 to 4.

Abstract: Provided herein are compositions and methods for the induction and/or proliferation of CD8+ T-cells. The disclosure also provides methods of treatment of diseases that can be treated by the induction and/or proliferation of CD8+ T-cells.

Abstract: A database management system (DBMS) generates a query execution plan including information representing one or more database (DB) operations necessary for executing a query and executes the query based on the query execution plan. In the execution of the query, the DBMS dynamically generates a task for executing a DB operation and executes the dynamically generated task. The DBMS executes a task in a plurality of threads executed by a processor core.

Abstract: [Problem] To provide a fluorescent probe that detects calpain activity in cells at high sensitivity. [Solution] A compound represented by the following general formula (I) or a salt thereof.