Patents Assigned to Tomei Sangyo Kabushiki Kaisha
  • Patent number: 5487788
    Abstract: A method of cleaning and disinfecting a contact lens comprising immersing a contact lens in a treating solution, applying a direct current to the treating solution with repeatedly reversing a positive electrode and a negative electrode of a pair of electrodes plural times to generate peroxide and raise the temperature of the treating solution so that the interval of time before reversing is different from or equal to the interval of time after reversing to 50.degree. to 100.degree. C., and bringing the contact lens into direct contact with bubbles generated on the electrodes. Since this method is excellent in electrical safety and cleaning and disinfecting effects, contact lenses can be easily cleaned and disinfected.
    Type: Grant
    Filed: May 9, 1994
    Date of Patent: January 30, 1996
    Assignee: Tomei Sangyo Kabushiki Kaisha
    Inventors: Hideaki Kamiya, Satoshi Hashimoto, Satoru Matumoto
  • Patent number: 5460658
    Abstract: A liquid composition for contact lenses, which comprises from 0.01 to 5% (W/V) of a protease, from 5 to 30% (W/V) of a polyhydric alcohol, from 1 to 5% (W/V) of an alkali metal salt and from 0.5 to 20% (W/V) of a surfactant.
    Type: Grant
    Filed: June 17, 1994
    Date of Patent: October 24, 1995
    Assignee: Tomei Sangyo Kabushiki Kaisha
    Inventors: Akira Nakagawa, Kaoru Kamiya
  • Patent number: 5409731
    Abstract: A method for imparting a hydrophilic nature to a contact lens, which comprises dipping a contact lens in a solution containing a water-soluble amino group-containing polymer in an amount effective to impart a hydrophilic nature to the contact lens and a crosslinking agent in an amount effective to crosslink the amino group-containing polymer, and forming a hydrophilic layer of the amino group-containing polymer crosslinked on the surface of the contact lens.
    Type: Grant
    Filed: October 8, 1992
    Date of Patent: April 25, 1995
    Assignee: Tomei Sangyo Kabushiki Kaisha
    Inventors: Akira Nakagawa, Teruyo Komura
  • Patent number: 5409546
    Abstract: A method for cleaning and preserving a contact lens, characterized by using a treating solution containing an effective amount of a serine protease derived from bacteria belonging to genus Bacillus, a metal chelating agent, and boric acid and/or borax which stabilizes the serine protease at room temperature and having the osmotic pressure adjusted to a level of from 200 to 600 mOsm/kg-water, which method comprises dispensing the treating solution at the time of treatment, and immersing a contact lens in the dispensed treating solution.
    Type: Grant
    Filed: October 8, 1993
    Date of Patent: April 25, 1995
    Assignee: Tomei Sangyo Kabushiki Kaisha
    Inventors: Akira Nakagawa, Yoshiko Oi
  • Patent number: 5401431
    Abstract: A cleaning-preserving aqueous solution for contact lenses, which contains, as a surfactant, a tetra-fatty acid polyoxyethylene sorbitol of the formula 1: ##STR1## wherein a+b+c+d+e+f=20 to 50, and four among R.sub.1 to R.sub.6 are C.sub.12-18 saturated or unsaturated fatty acid residues and the remaining two are hydrogen atoms, and which has a physiological osmotic pressure and has a pH adjusted to a level of from 4 to 9.
    Type: Grant
    Filed: September 29, 1993
    Date of Patent: March 28, 1995
    Assignee: Tomei Sangyo Kabushiki Kaisha
    Inventors: Akira Nakagawa, Kisaki Maezawa
  • Patent number: 5314590
    Abstract: An method for cleaning and disinfecting a soft contact lens, characterized by immersing the soft contact lens in a treating solution which does not generate any hypohalite during electrolysis, supplying a direct current, and raising the temperature of the treating solution; and a treating solution for a soft contact lens, characterized by containing a treating agent mainly composed of boric acid and borax in a concentration of at most 2.2 w/v % and having an electrical conductivity of at most 8 mS/cm are disclosed.
    Type: Grant
    Filed: March 29, 1993
    Date of Patent: May 24, 1994
    Assignee: Tomei Sangyo Kabushiki Kaisha
    Inventors: Hideaki Kamiya, Makoto Nakagawa
  • Patent number: 5314823
    Abstract: A method for cleaning a contact lens, which comprises diluting an enzyme-containing aqueous solution containing an effective amount of serine protease and from 30 to 95% by weight of glycerol with a diluting solution containing from 0.05 to 5% by weight of an anionic surfactant having no polyoxyethylene glycol unit and from 0.005 to 0.1% by weight of ethylenediamine tetraacetate to a glycerol concentration of not higher than 5% by weight, to obtain a treating solution, and immersing a contact lens in the treating solution.
    Type: Grant
    Filed: October 20, 1992
    Date of Patent: May 24, 1994
    Assignee: Tomei Sangyo Kabushiki Kaisha
    Inventor: Akira Nakagawa
  • Patent number: 5302312
    Abstract: A detergent for a contact lens comprising 40 to 80% by weight of fine particles of a water-soluble compound which has a salt value of at most 0.65 and a solubility in water of 3 to 30 at 30.degree. C. and at most 40 at 60.degree. C., with the product of the salt value and the solubility at 30.degree. C. being at most 10, and 100% of which passes a JIS standard sieve of a nominal size of 75 .mu.m, and 60 to 20% by weight of a pasting agent containing as a major component an aqueous dispersion of a gel composed of an acrylic acid compound having a recurring unit represented by the general formula (I): ##STR1## wherein R.sub.1 represents hydrogen atom and/or methyl group, R.sub.2 represents at least one member selected from hydrogen atom, sodium atom, potassium atom, lithium atom, NH.sub.
    Type: Grant
    Filed: November 27, 1991
    Date of Patent: April 12, 1994
    Assignee: Tomei Sangyo Kabushiki Kaisha
    Inventors: Atsushi Kawai, Megumi Nozawa, Shoko Kanda, Kenji Kodama, Hidetake Sendai
  • Patent number: 5283053
    Abstract: A contact lens treating vessel equipped with an electromagnetic induction coil and a rectifier for converting an alternating current into a direct current, and an apparatus for treating contact lenses comprising a treating apparatus body for supplying electric power and the vessel which can be attached to or detached from the apparatus body, wherein the apparatus body is equipped with a magnet-generating coil and the vessel is equipped with an electromagnetic induction coil.
    Type: Grant
    Filed: October 21, 1992
    Date of Patent: February 1, 1994
    Assignee: Tomei Sangyo Kabushiki Kaisha
    Inventors: Hideaki Kamiya, Makoto Nakagawa, Masashi Endo, Masakatsu Yamauchi
  • Patent number: 5281277
    Abstract: A liquid composition for contact lenses, having from 5 to 40% (w/v) of glycerol and from 4 to 20% (w/v) of boric acid and/or a borate incorporated to a solution containing an effective amount of a protease, in such a ratio that the boric acid and/or the borate is from 10 to 100 parts, preferably 10-20 parts, by weight per 100 parts by weight of the glycerol.
    Type: Grant
    Filed: April 8, 1992
    Date of Patent: January 25, 1994
    Assignee: Tomei Sangyo Kabushiki Kaisha
    Inventors: Akira Nakagawa, Satoko Kondo, Yoshiko Oi
  • Patent number: 5246552
    Abstract: An method for cleaning and disinfecting a soft contact lens, characterized by immersing the soft contact lens in a treating solution which does not generate any hypohalite during electrolysis, supplying a direct current, and raising the temperature of the treating solution; and a treating solution for a soft contact lens, characterized by containing a treating agent mainly composed of boric acid and borax in a concentration of at most 2.2 w/v % and having an electrical conductivity of at most 8 mS/cm are disclosed.
    Type: Grant
    Filed: May 20, 1991
    Date of Patent: September 21, 1993
    Assignee: Tomei Sangyo Kabushiki Kaisha
    Inventors: Hideaki Kamiya, Makoto Nakagawa
  • Patent number: 5244470
    Abstract: A method for tinting a water-absorptive contact lens to have a mark tinted thereon, which comprises superimposing on a water-absorptive contact lens in the dry state a screen provided with a tinting pattern corresponding to the mark to be tinted on the contact lens, applying to the contact lens through the tinting pattern of the screen a dye solution containing a vat dye and an alkaline reducing agent, followed by insolubilizing the vat dye.
    Type: Grant
    Filed: January 28, 1992
    Date of Patent: September 14, 1993
    Assignees: Menicon Co., Ltd., Tomei Sangyo Kabushiki Kaisha
    Inventors: Koji Onda, Toshihisa Sakai, Yasuhiro Yokoyama, Takanori Shibata, Yasuyuki Kato
  • Patent number: 5206298
    Abstract: A graft copolymer produced by polymerizing 2-hydroxyethyl methacrylate, or monomer mixture containing the monomer, by using initiator produced by copolymerizing (A) N-vinyllactam or styrene and (B) peroxy-fumarate or combination of the peroxy-fumarate and diester of fumaric acid, the peroxy-fumarate being represented by the formula (I): ##STR1## wherein R1 is a linear alkyl, branched alkyl or cycloalkyl group containing not more than 18 carbon atoms, or an aromatic hydrocarbon group containing 6 to carbon atoms; and R2 is a linear alkyl, branched alkyl or cycloalkyl group containing not more than 13 carbon atoms, or a phenyl group.A solution for treating a contact lens, including the above graft copolymer and a solvent dissolving the copolymer.
    Type: Grant
    Filed: December 14, 1990
    Date of Patent: April 27, 1993
    Assignee: Tomei Sangyo Kabushiki Kaisha
    Inventor: Toru Kawaguchi
  • Patent number: 5142009
    Abstract: A hard contact lens material comprising a copolymer made of at least two kinds of fumaric acid diester at least one of which is a dialkyl fumarate as main components. The hard contact lens material has high oxygen permeability, transparance and excellent physical properties.
    Type: Grant
    Filed: June 22, 1988
    Date of Patent: August 25, 1992
    Assignee: Tomei Sangyo Kabushiki Kaisha
    Inventor: Toru Kawaguchi
  • Patent number: 5134213
    Abstract: A polymer-type polymerization initiator produced by copolymerizing (A) 40 to 60 mole % of an N-vinyllactam and (B) 60 to 40 mole % of at least one fumarate containing a peroxy group, the peroxy-fumarate (B) being represented by the following formula: ##STR1## wherein R1 is a linear alkyl, branched alkyl or cycloalkyl group containing not more than 18 carbon atoms, or an aromatic hydrocarbon group containing 6 to 18 carbon atoms; and R2 is a linear alkyl, branched alkyl or cycloalkyl group containing not more than 13 carbon atoms, or a phenyl group.The peroxy-fumarate (b1) may be used in combination with (b2) at least one diester of fumaric acid selected from the group consisting of alkyl fluoroalkyl fumarate, alkyl silicon-containing-alkyl fumarate, fluoroalkyl silicon-containing-alkyl fumarate, bis(fluoroalkyl) fumarate, and bis(silicon-containing-alkyl) fumarate, a mole ratio of the peroxy-fumarate to the diester of fumaric acid falling within a range of 9 to 1 to 1 to 9.
    Type: Grant
    Filed: September 3, 1991
    Date of Patent: July 28, 1992
    Assignee: Tomei Sangyo Kabushiki Kaisha
    Inventor: Toru Kawaguchi
  • Patent number: 5082912
    Abstract: A polymer-type polymerization initiator produced by copolymerizing (A) 40 to 60 mole % of an N-vinyllactam and (B) 60 to 40 mole % of at least one fumarate containing a peroxy group, the peroxy-fumarate (B) being represented by the following formula: ##STR1## wherein R1 is a linear alkyl, branched alkyl or cycloalkyl group containing not more than 18 carbon atoms, or an aromatic hydrocarbon group containing 6 to 18 carbon atoms; and R2 is a linear alkyl, branched alkyl or cycloalkyl group containing not more than 13 carbon atoms, or a phenyl group.The peroxy-fumarate (b1) may be used in combination with (b2) at least one diester of fumaric acid selected from the group consisting of alkyl fluoroalkyl fumarate, alkyl silicon-containing-alkyl fumarate, fluoroalkyl, silicon-containing-alkyl fumarate, bis(fluoroalkyl) fumarate, and bis(silicon-containing-alkyl) fumarate, a mole ratio of the peroxy-fumarate to the diester of fumaric acid falling within a range of 9 to 1 to 1 to 9.
    Type: Grant
    Filed: December 11, 1990
    Date of Patent: January 21, 1992
    Assignee: Tomei Sangyo Kabushiki Kaisha
    Inventor: Toru Kawaguchi
  • Patent number: 4940542
    Abstract: A device for dispensing a liquid, including a container having an interior space accommodating the liquid, a first valve attached to the container, a delivery path having one end submerged in the liquid and extending through the container such that the other end is outside the container, and a second valve disposed in the delivery path for closing and opening the delivery path. The first valve permits a pressurized gas to flow therethrough into the container to raise the pressure within the container, but inhibits a discharge flow of the pressurized gas and the liquid therethrough out of the interior space. The liquid is delivered out of the container through the delivery path, due to the raised pressure within the interior space. The device has a micro-porous membrane filter disposed in a portion of the delivery path which is located upstream of the second valve, as viewed in the direction of delivery of the liquid.
    Type: Grant
    Filed: October 27, 1989
    Date of Patent: July 10, 1990
    Assignees: Tomei Sangyo Kabushiki Kaisha, Mitsubishi Rayon Co., Ltd.
    Inventors: Kazuo Simizu, Shin Sakai, Satoru Matsumoto, Osamu Yamamoto, Hisao Tanaka
  • Patent number: 4904421
    Abstract: A method for preparing a soft ocular lens, which comprises machining a machinably hard polymer blend body composed essentially of a soft lens material and a hard polymer into an ocular lens shape, and removing the hard polymer from the shaped product.
    Type: Grant
    Filed: November 12, 1987
    Date of Patent: February 27, 1990
    Assignee: Tomei Sangyo Kabushiki Kaisha
    Inventors: Ichiro Ando, Toru Kawaguchi
  • Patent number: 4868260
    Abstract: A hard contact lens material comprising a copolymer made of at least two kinds of fumaric acid diester at least one of which is a dialkyl fumarate as main components. The hard contact lens material has high oxygen permeability, transparance and excellent physical properties.
    Type: Grant
    Filed: October 24, 1986
    Date of Patent: September 19, 1989
    Assignee: Tomei Sangyo Kabushiki Kaisha
    Inventor: Toru Kawaguchi
  • Patent number: 4788227
    Abstract: An optically transparent hydrogen forming material comprising a copolymer of an optically transparent polyester having a molecular weight of 1,000 to 100,000 and at least one of polymerizable group in its molecule and N-vinyllactam. The hydrogel forming material has an excellent optical property, high gas-permeability and excellent mechanical property.
    Type: Grant
    Filed: March 18, 1987
    Date of Patent: November 29, 1988
    Assignee: Tomei Sangyo Kabushiki Kaisha
    Inventors: Yasukichi Yanagihara, Takuo Kato