Abstract: The present application discloses modified release mucoadhesive formulations of mycophenolate mofetil and pharmaceutical compositions thereof useful in the treatment of, for example, post-transplant organ rejection. Method of preparing the formulations is also disclosed.

Abstract: Described are methods and uses employing metabolomic data to diagnose an asthma disease state or a Chronic Obstructive Pulmonary Disease (COPD) state. Further described are methods of uses of employing metabolomic data to distinguish between asthma and COPD. In particular, urinary metabolomic profiles are employed to enable differential diagnosis of asthma and COPD.

Abstract: Arrays of low permittivity Polymer-based Resonator Antenna elements with different configurations. Individual array elements can be fabricated with complicated geometries; these elements can be assembled into complicated patterns as a single monolithic fabricated structure using narrow wall connecting structures, which removes the requirement to position and assemble the array elements. Monolithic array structures can be assembled as sub-arrays in larger array structures. Elements, sub-arrays, and arrays can also be formed by inserting dielectric materials into cavities defining their lateral geometries, and fabricated in polymer templates. The polymer templates can be removed or retained to function as part of the antenna.

Abstract: Methods of detecting pipeline weakening are described herein. The methods include creating a pressure wave in a fluid flowing in a pipeline using an input transducer located at a first position along the pipeline; measuring the pressure wave using an output transducer positioned at a second position along the pipeline that is spaced from the first position, and generating an output signal based on the pressure wave; analyzing the output signal to determine a stiffness of a sidewall of the pipeline positioned between the input transducer and output transducer; and determining if the sidewall includes a defect based on the stiffness of the sidewall, including analyzing a frequency response of the output signal to detect the defect.

Abstract: Nucleic acid molecules encoding polypeptides having polyketide synthase activity have been identified and characterized. Expression or over-expression of the nucleic acids alters levels of cannabinoid compounds in organisms. The polypeptides may be used in vivo or in vitro to produce cannabinoid compounds.

Abstract: The present application discloses modified release mucoadhesive formulations of mycophenolate mofetil and pharmaceutical compositions thereof useful in the treatment of, for example, post-transplant organ rejection. Method of preparing the formulations is also disclosed.

Abstract: Dielectric resonator antennas suitable for use in compact radiofrequency (RF) antennas and devices, and methods of fabrication thereof. Described are dielectric resonator antennas fabricated using polymer-based materials, such as those commonly used in lithographic fabrication of integrated circuits and microsystems. Accordingly, lithographic fabrication techniques can be employed in fabrication. The polymer-based dielectric resonator antennas can be excited using tall metal vertical structures, which are also fabricated using techniques adapted from integrated circuit and microsystems fabrication.

Abstract: Antennas suitable for use in compact radio frequency (RF) applications and devices, and methods of fabrication thereof. Described are resonator antennas, for example dielectric resonator antennas fabricated using polymer-based materials, such as those commonly used in lithographic fabrication of integrated circuits and microsystems. Accordingly, lithographic fabrication techniques can be employed in fabrication. The antennas have metal inclusions embedded in the resonator body which can be configured to control electromagnetic field patterns, which serves to enhance the effective permittivity of the resonator body, while creating an anisotropic material with different effective permittivity and polarizations in different orientations.

Abstract: An energy exchanger is provided. The exchanger includes a housing having a front and a back. A plurality of panels forming desiccant channels extend from the front to the back of the housing. Air channels are formed between adjacent panels. The air channels are configured to direct an air stream in a direction from the front of the housing to the back of the housing. A desiccant inlet is provided in flow communication with the desiccant channels. A desiccant outlet is provided in flow communication with the desiccant channels. The desiccant channels are configured to channel desiccant from the desiccant inlet to the desiccant outlet in at least one of a counter-flow or cross-flow direction with respect to the direction of the air stream.

Abstract: The present application includes iron catalysts promoted with Mo, K and optionally Cu on a multi-walled carbon nanotube (MWCNT) support for high molecular weight hydrocarbon synthesis from synthesis gas.

Abstract: The present disclosure provides novel endophyte strains or cultures thereof that have a symbiotic relationship with plants. The present disclosure further provides methods of improving seed vitality, biotic and abiotic stress resistance, plant health and yield under both stressed and unstressed environmental conditions, comprising inoculating a seed with the novel endophyte strains and cultivating a plant therefrom.

Abstract: The present application relates to topical formulations in the form of an oil-in-water emulsion comprising nifedipine and a photostabilizing effective amount of quercetin or a photostabilizing effective amount of a combination of quercetin and butyl methoxydibenzoylmethane (BMDBM). Such topical formulations may, for example, be used for the treatment of diseases, disorders or conditions that benefit from topical administration of nifedipine such as but not limited to Raynaud phenomenon, chilblains or wound healing.

Abstract: Immunogens, compositions and methods for treating, preventing and/or diagnosing PEDV infection in pigs are disclosed. The compositions and methods use inactivated or attenuated virus-containing vaccines, or subunit vaccines, including immunogens and mixtures of immunogens derived from PEDV isolates.

Abstract: The present disclosure provides compositions comprising novel endophytes capable of promoting germination endophytes that have a symbiotic relationship with plants. The present disclosure further provides methods of improving seed vitality, biotic and abiotic stress resistance, plant health and yield under both stressed and unstressed environmental conditions, comprising inoculating a seed with the novel endophyte strains and cultivating a plant therefrom.

Abstract: The disclosure relates to immunogenic and vaccine compositions comprising Streptococcus exotoxins and/or bacterial thermolysins from M4 protease family. Also provided are kits, methods and uses of said compositions for treating or preventing laminitis in a hooved animal.

Abstract: Recombinant, chimeric porcine influenza viruses are disclosed that include hemagglutinin segments from more than one influenza virus subtype. Also described are methods of producing the recombinant influenza viruses, immunogenic compositions comprising the recombinant influenza viruses, methods of stimulating an immune response against influenza virus, and methods of treating and preventing influenza virus infection.

Abstract: Nucleic acid molecules encoding polypeptides having polyketide synthase activity have been identified and characterized. Expression or over-expression of the nucleic acids alters levels of cannabinoid compounds in organisms. The polypeptides may be used in vivo or in vitro to produce cannabinoid compounds.

Abstract: An intravaginal device that provides biologically active circulating concentrations of an aromatase inhibitor for at least about of 4 days. Liposome-based and a wax-based formulations were used to assess letrozole diffusion through bovine vaginal mucosa in a diffusion chamber study. The wax-based vehicle was selected for further development of a letrozole intravaginal device based on its steady release rate. The addition of a letrozole-containing gel coating improved initial absorption and hastened the increase on plasma concentrations of the active ingredient, while the letrozole-containing wax-based vehicle maintained prolonged delivery from the intravaginal device.

Abstract: The present applications relates to methods for the simultaneous leaching and extraction of precious metals. For example, the present application relates to methods of leaching and extracting gold and/or palladium from a substance comprising gold and/or palladium such as a gold- and/or palladium-containing ore in one step using a compound of Formula I:(I).

Abstract: The present invention is directed to lentil plants having increased resistance to an imidaizolinone herbicide. One such plant described herein is the RH44 lentil variety. The present invention also includes seeds produced by these lentil plants and methods of controlling weeds in the vicinity of these lentil plants.