Patents Assigned to Valeritas, Inc.
  • Publication number: 20180028743
    Abstract: A fluid delivery device for administering a first medicament and a second medicament includes a first fluid reservoir configured to contain the first medicament and a second fluid reservoir configured to contain the second medicament. The fluid delivery device may include one or more basal drive mechanisms to provide a basal delivery of one or more of the first and second medicaments. The fluid delivery device may further include one or more bolus drive mechanisms to provide a bolus delivery of one or more of the first and second medicaments.
    Type: Application
    Filed: May 17, 2017
    Publication date: February 1, 2018
    Applicant: Valeritas, Inc.
    Inventors: Robert R. GONNELLI, Steven F. LEVESQUE, Ronald V. NARDI
  • Publication number: 20170361016
    Abstract: A fluid delivery device includes an automatic needle retraction mechanism configured to automatically retract a delivery end of a needle into a housing. In one embodiment, the needle assembly is configured to automatically withdraw the delivery end of the needle into the housing upon an actuator moving from the first position to the second position. In one embodiment, the needle assembly is configured to automatically withdraw the delivery end of the needle into the housing upon decoupling a bottom surface of the housing from a skin surface.
    Type: Application
    Filed: September 6, 2017
    Publication date: December 21, 2017
    Applicant: Valeritas, Inc.
    Inventors: Steven F. Levesque, Geoffrey H. Jenkins, Robert L. Standley, Matthew P. Johnson, Daniel A. Dube, Jr.
  • Patent number: 9833383
    Abstract: A fluid transfer device for transferring fluid between a supply reservoir and a fill reservoir includes a metering reservoir and a manifold that forms at least part of a first channel that is fluidly connected with the metering reservoir. The first channel comprises a first cannula extending from the manifold. The manifold forms at least part of a second channel fluidly connected with the metering reservoir. The second channel comprises a second cannula extending from the manifold. A third channel extends through the manifold and comprises a third cannula having a first end proximate a distal end of the first cannula and a second end proximate a distal end of the second cannula. A first check valve is disposed within the first channel and a second check valve is disposed within the second channel.
    Type: Grant
    Filed: May 26, 2016
    Date of Patent: December 5, 2017
    Assignee: VALERITAS, INC.
    Inventors: Robert R. Gonnelli, Robert L. Standley, Steven F. Levesque
  • Patent number: 9814831
    Abstract: A fluid delivery device comprises a fluid reservoir for containing medicament. The fluid reservoir is sealed proximate one end with a sliding seal piston. A delivery path is configured to fluidly couple the fluid reservoir and a patient wearing the fluid delivery device. A basal engine mechanism is configured to directly or indirectly move the sliding seal piston in the fluid reservoir at a controlled basal rate. A bolus mechanism configured to move the basal engine relative to the fluid reservoir and directly or indirectly move the sliding seal piston in the fluid reservoir a discrete bolus amount at a time.
    Type: Grant
    Filed: January 28, 2015
    Date of Patent: November 14, 2017
    Assignee: VALERITAS, INC.
    Inventor: Robert R. Gonnelli
  • Patent number: 9795735
    Abstract: A fluid delivery device includes an automatic needle retraction mechanism configured to automatically retract a delivery end of a needle into a housing. In one embodiment, the needle assembly is configured to automatically withdraw the delivery end of the needle into the housing upon an actuator moving from the first position to the second position. In one embodiment, the needle assembly is configured to automatically withdraw the delivery end of the needle into the housing upon decoupling a bottom surface of the housing from a skin surface.
    Type: Grant
    Filed: April 23, 2014
    Date of Patent: October 24, 2017
    Assignee: VALERITAS, INC.
    Inventors: Steven F. Levesque, Geoffrey H. Jenkins, Robert L. Standley, Matthew P. Johnson, Daniel A. Dube, Jr.
  • Publication number: 20170296741
    Abstract: A fluid delivery device comprises a drive unit including an actuator and one or more first features and a cartridge filled with a fluid prior to being inserted into the housing. The cartridge having a fluid reservoir sealed at one end by a movable piston and sealed at another end by a pierceable septum. The cartridge includes one or more second features that are configured to align and mate with the one or more first features allowing the cartridge to be inserted into the drive unit. The piston is moveable by the actuator once the cartridge is inserted into the drive unit.
    Type: Application
    Filed: October 12, 2015
    Publication date: October 19, 2017
    Applicant: Valeritas, Inc.
    Inventor: Christopher C. Gregory
  • Publication number: 20170189610
    Abstract: Fluid delivery and measurement systems and methods are disclosed.
    Type: Application
    Filed: March 21, 2017
    Publication date: July 6, 2017
    Applicant: Valeritas, Inc.
    Inventors: Robert R. Gonnelli, Steven F. Levesque, David Lipson, Peter F. Marshall
  • Patent number: 9687599
    Abstract: A fluid delivery device for administering a first medicament and a second medicament includes a first fluid reservoir configured to contain the first medicament and a second fluid reservoir configured to contain the second medicament. The fluid delivery device may include one or more basal drive mechanisms to provide a basal delivery of one or more of the first and second medicaments. The fluid delivery device may further include one or more bolus drive mechanisms to provide a bolus delivery of one or more of the first and second medicaments.
    Type: Grant
    Filed: July 28, 2014
    Date of Patent: June 27, 2017
    Assignee: VALERITAS, INC.
    Inventors: Robert R. Gonnelli, Steven F. Levesque, Ronald V. Nardi
  • Patent number: 9636451
    Abstract: Fluid delivery and measurement systems and methods are disclosed.
    Type: Grant
    Filed: February 24, 2015
    Date of Patent: May 2, 2017
    Assignee: VALERITAS, INC.
    Inventors: Robert R. Gonnelli, Steven F. Levesque, David Lipson, Peter F. Marshall
  • Publication number: 20170035966
    Abstract: A fluid delivery device comprises a hydraulic pump chamber having a hydraulic fluid. A fluid reservoir is coupled to the hydraulic pump chamber and is configured to contain a fluid deliverable to a patient. A first actuator is coupled to the hydraulic pump chamber and is configured to pressurize the hydraulic pump chamber and configured to transfer energy through the hydraulic pump chamber to the fluid reservoir. A second actuator is coupled to the hydraulic pump chamber and is configured to pressurize the hydraulic pump chamber and configured to transfer energy through the hydraulic pump chamber to the fluid reservoir.
    Type: Application
    Filed: October 21, 2016
    Publication date: February 9, 2017
    Applicant: Valeritas, Inc.
    Inventors: Robert R. Gonnelli, Devin V. McAllister, Steven F. Levesque
  • Patent number: 9561042
    Abstract: The invention provides for microneedle devices for delivering agents across biological barriers. The microneedles include agent reservoirs integrated into the bodies of the microneedles, themselves.
    Type: Grant
    Filed: November 12, 2009
    Date of Patent: February 7, 2017
    Assignee: Valeritas, Inc.
    Inventors: Devin V. McAllister, Ciro DiMeglio
  • Publication number: 20170000942
    Abstract: A fluid delivery device comprises a fluid reservoir for containing medicament. The fluid reservoir is sealed proximate one end with a sliding seal piston. A delivery path is configured to fluidly couple the fluid reservoir and a patient wearing the fluid delivery device. A basal engine mechanism is configured to directly or indirectly move the sliding seal piston in the fluid reservoir at a controlled basal rate. A bolus mechanism configured to move the basal engine relative to the fluid reservoir and directly or indirectly move the sliding seal piston in the fluid reservoir a discrete bolus amount at a time.
    Type: Application
    Filed: January 28, 2015
    Publication date: January 5, 2017
    Applicant: Valeritas, Inc.
    Inventor: Robert R. Gonnelli
  • Patent number: 9511187
    Abstract: A fluid delivery device comprises a hydraulic pump chamber having a hydraulic fluid. A fluid reservoir is coupled to the hydraulic pump chamber and is configured to contain a fluid deliverable to a patient. A first actuator is coupled to the hydraulic pump chamber and is configured to pressurize the hydraulic pump chamber and configured to transfer energy through the hydraulic pump chamber to the fluid reservoir. A second actuator is coupled to the hydraulic pump chamber and is configured to pressurize the hydraulic pump chamber and configured to transfer energy through the hydraulic pump chamber to the fluid reservoir.
    Type: Grant
    Filed: July 27, 2015
    Date of Patent: December 6, 2016
    Assignee: VALERITAS, INC.
    Inventors: Robert R. Gonnelli, Devin V. McAllister, Steven F. Levesque
  • Publication number: 20160262983
    Abstract: A fluid transfer device for transferring fluid between a supply reservoir and a fill reservoir includes a metering reservoir and a manifold that forms at least part of a first channel that is fluidly connected with the metering reservoir. The first channel comprises a first cannula extending from the manifold. The manifold forms at least part of a second channel fluidly connected with the metering reservoir. The second channel comprises a second cannula extending from the manifold. A third channel extends through the manifold and comprises a third cannula having a first end proximate a distal end of the first cannula and a second end proximate a distal end of the second cannula. A first check valve is disposed within the first channel and a second check valve is disposed within the second channel.
    Type: Application
    Filed: May 26, 2016
    Publication date: September 15, 2016
    Applicant: Valeritas, Inc.
    Inventors: Robert R. Gonnelli, Robert L. Standley, Steven F. Levesque
  • Patent number: 9415198
    Abstract: A method and apparatus for application of a microneedle patch to a skin surface of a patient includes use of an applicator. The applicator includes a housing, a slidably disposed applicator plate, and a compression spring. The applicator plate is moveable between a retracted position and a deployed position, and has an engaging surface suitable for mashing up against a microneedle patch and pressing it against a skin surface. A docking system transfers the microneedle patch from a support to the applicator without requiring a user to handle the microneedle patch directly. Once mounted in the applicator, the microneedle patch is deployed against a skin surface of a patient for delivery of a desired agent via a microneedle array contained on the patch.
    Type: Grant
    Filed: October 9, 2015
    Date of Patent: August 16, 2016
    Assignee: Valeritas, Inc.
    Inventor: Devin V. McAllister
  • Patent number: 9376224
    Abstract: A fluid transfer device for transferring fluid between a supply reservoir and a fill reservoir includes a metering reservoir and a manifold that forms at least part of a first channel that is fluidly connected with the metering reservoir. The first channel comprises a first cannula extending from the manifold. The manifold forms at least part of a second channel fluidly connected with the metering reservoir. The second channel comprises a second cannula extending from the manifold. A third channel extends through the manifold and comprises a third cannula having a first end proximate a distal end of the first cannula and a second end proximate a distal end of the second cannula. A first check valve is disposed within the first channel and a second check valve is disposed within the second channel.
    Type: Grant
    Filed: January 16, 2014
    Date of Patent: June 28, 2016
    Assignee: VALERITAS, INC.
    Inventors: Robert R. Gonnelli, Robert L. Standley, Steven F. Levesque
  • Publication number: 20160082182
    Abstract: A fluid delivery device comprises a housing having a bottom surface configured to be coupled to the skin surface. The fluid delivery device includes a cartridge prefilled with a fluid and configured to be inserted into the housing. The cartridge has a septum configured to be generally perpendicular to the bottom surface when the cartridge is inserted in the housing. The fluid delivery device includes a needle assembly that has a needle that includes a fluid coupling end and a delivery end. The fluid coupling end of the needle is fluidly disengaged from the cartridge in an initial position. The delivery end of the needle extends past the plane of the bottom surface and the fluid coupling end of the needle extends through the septum in a deployed position.
    Type: Application
    Filed: May 30, 2014
    Publication date: March 24, 2016
    Applicant: VALERITAS, INC.
    Inventors: Christopher C. Gregory, Matthew P. Johnson, Roberl L. Standley
  • Publication number: 20150328400
    Abstract: A fluid delivery device comprises a hydraulic pump chamber having a hydraulic fluid. A fluid reservoir is coupled to the hydraulic pump chamber and is configured to contain a fluid deliverable to a patient. A first actuator is coupled to the hydraulic pump chamber and is configured to pressurize the hydraulic pump chamber and configured to transfer energy through the hydraulic pump chamber to the fluid reservoir. A second actuator is coupled to the hydraulic pump chamber and is configured to pressurize the hydraulic pump chamber and configured to transfer energy through the hydraulic pump chamber to the fluid reservoir.
    Type: Application
    Filed: July 27, 2015
    Publication date: November 19, 2015
    Applicant: VALERITAS, INC.
    Inventors: Robert R. Gonnelli, Devin V. McAllister, Steven F. Levesque
  • Publication number: 20150314065
    Abstract: The invention provides various devices for delivering Glucagon-Like Peptide-1 (7-36), in various infusion patterns and rates, to optimally stimulate carbohydrate metabolism, to inhibit gastropancreatic secretion and gastric motility, and to treat various disease conditions (including diabete) as described in the instant specification. The devices and methods of the invention provide various ways to deliver doses (escalating, constant, on demand, etc.) of GLP-1 in response to different patient need.
    Type: Application
    Filed: June 15, 2015
    Publication date: November 5, 2015
    Applicant: VALERITAS, INC.
    Inventor: Robert R. Gonnelli
  • Publication number: 20150306306
    Abstract: A fluid delivery device comprises a housing having a fluid reservoir. A needle is in fluid communication with the fluid reservoir in an engaged position and out of fluid communication with the fluid reservoir in armed and storage positions. A proximal end of a biasing member is coupled to the housing and a distal end of the biasing member is configured to deliver a force to the fluid reservoir. A piston member extends through the biasing member and is coupled to the distal end of the biasing member. The piston member is fixed with respect to the housing in a locked position such that the biasing member does not deliver the force to the fluid reservoir and moveable with respect to the housing in a released position such that the biasing member delivers the force to the fluid reservoir. Transitioning the needle from the storage position to the armed position transitions the piston from the locked position to the released position.
    Type: Application
    Filed: July 2, 2015
    Publication date: October 29, 2015
    Applicant: VALERITAS, INC.
    Inventors: Robert R. Gonnelli, Steven F. Levesque