Abstract: An injection system includes a handle assembly with a handle body having an outer surface surrounding a handle body interior and a plunger extending therethrough. A tubular handle collar is telescopically received in the handle body exterior and is axially movable with respect to the handle body. A syringe housing assembly is selectively connectable to the handle assembly and includes a syringe housing and a tubular syringe sleeve telescopically received through a distal end of the syringe housing and axially movable with respect thereto. The syringe housing has an exterior side surface surrounding a syringe housing interior configured to receive at least a portion of a syringe. The syringe sleeve has a proximal end, a distal end with a skin contact surface, and a generally cylindrically-shaped outer surface.

Abstract: A needle shield remover for removing a needle shield covering a needle on a syringe includes a body having a proximal portion and a distal portion. The distal portion is moveable between a contracted configuration and an expanded configuration in response to opposite movement of the proximal portion. The distal portion includes an internal opening for receiving and at least partially surrounding a needle shield therein. An anchor extends inwardly from the distal portion into engagement with the needle shield when the distal portion is in the contracted configuration to secure the body to the needle shield. A sleeve is in fixed axial arrangement with the proximal portion of the body. The axial engagement maintains the distal portion of the body in the contracted configuration such that force applied to the sleeve away from the body removes the needle shield and body from a syringe.

Abstract: A syringe includes a plunger having multiple sections of differing diameters or materials, and a barrel with a cavity into which the plunger is inserted. The barrel includes a first probe and a second probe opposite to one another such that an interior volume of the barrel is radially between the first and second probes. A microcontroller is configured to measure a capacitance between the first and second probes, with the measured capacitance having a first capacitance value when the first section of the plunger shaft is between the first and second probes and a second capacitance value different from the first capacitance value when a second section of the plunger shaft is between the first and second probes. The microcontroller is configured to determine that an injection has been completed when the second capacitance value is measured.

Abstract: A method of detecting and/or tracking use of a drug delivery device is disclosed. The drug delivery device includes a machine readable code and a visual indicator, and has pre-use and used states, such that use of the drug delivery device triggers a transition from the pre-use to the used state. The visual indicator has a first state when the drug delivery device is in the pre-use state and a different second state when the drug delivery device is in the used state. The method includes enabling a user device having an image sensor to capture an image of the drug delivery device, determining, by the user device processor from the captured image, whether the visual indicator of the drug delivery device is in the second state, and obtaining, by the processor, information from the machine readable code when the visual indicator is determined to be in the second state.

Abstract: A barrel is provided having open proximal end and a closed distal end, and at least one groove in an interior wall thereof. The groove(s) define a length extending a distance from the open end of the barrel toward the distal end of the barrel and defining a substantially constant depth and width along the length thereof. A piston is in sealing engagement with the interior wall of the barrel. The groove(s) permits fluid to bypass the piston when positioned along the groove(s). At least a portion of the piston is positioned distally from the groove(s), thereby sealing substance within the barrel.

Abstract: An injection system, including an injector having a dispensing mechanism configured to dispense a medicament, and a ready-to-use indicator. The ready-to-use indicator includes a controller configured to interact with the ready-to-use indicator and an audio and/or visual indicator, a temperature sensor, and a temperature analog having similar thermodynamic properties of the medicament. The temperature sensor is configured to detect a temperature of the temperature analog which represents the dynamic temperature of medicament as the medicament is heated or cooled. The temperature sensor is configured to communicate the detected temperature to the controller and to alert the controller when a preset temperature is reached. The ready-to-use indicator is configured to alert a user when the preset temperature is reached, signifying the medicament is thermally ready to be delivered by the dispensing mechanism. The audio and/or visual indicator is configured to display indicate one or more notifications to the user.

Abstract: A needle safety device has an outer tube within which a syringe barrel is slideably receivable. A collar in the outer tube is moveable relative thereto and rotatably attachable to the distal end of the barrel. A force member biases the outer tube in a distal direction. A track is formed in the inner surface of the outer tube. A pin extending radially outwardly from the collar slidingly engages the track. In a staging position, the barrel is inspectable. In a pre-injection position, the cannula extends a first length beyond the outer tube. In a full-insertion position, the cannula extends a second length greater than the first length beyond the outer tube. In a locked position, the cannula is entirely within the outer tube.

Abstract: A cover for a drug container piston array includes a plurality of cover sections configured for positioning over the drug container piston array. Each cover section includes an elongated cover section body having an open base end and a closed capped end, and a plurality of base sections or a web positioned between the plurality of cover sections and coupled to each base end. Packaging assemblies including a cover and a piston nest are also disclosed.

Abstract: An adapter for a syringe has a base portion having an insertion hole configured to surround and engage at least a portion of a barrel of the syringe. The base portion includes a top surface and an opposing bottom surface. At least one projection extends upwardly from the top surface of the base portion. At least one ramp portion is located proximate the at least one projection. A flange portion extends laterally outwardly from the base portion. The flange portion includes a top surface and an opposing bottom surface. The top surface of the base portion extends generally parallel to and is spaced between the top and bottom surfaces of the flange portion.

Abstract: A needle shield puller has a deformable tubular body including a proximal end having a proximal opening and a distal end. An opening extends from the proximal opening toward the distal end. The opening is shaped to accommodate a portion of a needle shield. The body has initial and tension states and the opening diameter is greater in the initial state. A cinch is secured to the body at the proximal opening to secure the needle shield puller to the needle shield. The cinch biases the cinch diameter to a relaxed cinch diameter less than the needle shield diameter. A handle at a distal end of the body allows a user to place the body in the tension state. An installation aid comprises an arm releasably engageable with the cinch and the proximal opening to expand the cinch diameter toward a maximum cinch diameter greater than the needle shield diameter.

Abstract: A tamper-evident closure for containers includes a closure shell having a top surface and a depending skirt. The top surface defines a first aperture therethrough and a frangible portion. The skirt defines an open lower end for engaging a container. A tamper-evident tearable member overlies the top surface of the closure shell and defines a second aperture overlying the first aperture. A removable closure cap overlies the top surface of the closure shell and the tearable member. The closure cap has an annular ring projecting downwardly from an underside of the closure cap and extending through the first and second apertures. The annular ring attaches to an underside of the frangible portion. At least partial removal of the closure cap from the top surface of the closure shell peels the frangible portion away from the top surface of the closure shell along the scoring, and tears the tamper-evident member.